Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 303 products for "Microtubule Associated".
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99%Color and Shape:Yellow SolidMolecular weight:527.632TTBK1-IN-2
CAS:TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.Formula:C18H13ClN4OPurity:99.81%Color and Shape:SolidMolecular weight:336.775Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Purity:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.92 kDa (Predicted)Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Purity:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.73kDa (Predicted)Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.849BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.3686Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purity:> 95% - >95.0% (SDS-PAGE)Color and Shape:Transparent LiquidMolecular weight:145.3 kDa (Predicted)Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.893T-900607
CAS:T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.Formula:C14H10F5N3O4SPurity:99.98%Color and Shape:White SolidMolecular weight:411.30410-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.8633Tubulin polymerization-IN-62
Tubulin polymerization-IN-62 (Compound 14b) is a microtubule polymerization inhibitor (IC50 of 7.5 μM) that also functions as a degradation agent for α-/β-tubulin. This compound suppresses the proliferation of cancer cells MCF-7, A549, and HCT-116 with IC50 values of 32, 60, and 29 nM, respectively. It induces G2/M phase cell cycle arrest and inhibits the migration of MCF-7 cells. In a 4T1 syngeneic mouse model, Tubulin polymerization-IN-62 demonstrates antitumor efficacy with a tumor growth inhibition rate (TGI) of 74.27%.Formula:C37H44N4O4Color and Shape:SolidMolecular weight:608.33626(2S,3R)-Dap-NE hydrochloride
(2S,3R)-Dap-NE hydrochloride is an amino acid residue of the pentapeptide Dolastatin 10. Dolastatin 10 inhibits tubulin polymerization and mitosis, exhibiting anticancer properties.Formula:C18H29ClN2O3Color and Shape:SolidMolecular weight:356.186672-Methylthiophenothiazine
CAS:2-Methylthiophenothiazine, with CAS No. 7643-08-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Methylthiophenothiazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C13H11NS2Purity:99.89%Color and Shape:SolidMolecular weight:245.363Microtubule destabilizing agent-3, negative control
CAS:Microtubule destabilizing agent-3, negative control, is an analog of B32B3 and serves as the negative control for Microtubule destabilizing agent-3. This agent functions as a microtubule destabilizer by disrupting microtubule stability, which promotes mitotic arrest and exhibits an anti-myeloma phenotype, ultimately leading to cell death. It can also induce G2/M phase arrest and caspase-dependent apoptosis.Formula:C17H18N4SMolecular weight:310.42Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cellFormula:C24H20FN3O3Color and Shape:SolidMolecular weight:417.43Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83E7130
E7130 is a microtubule inhibitor that enhances the tumor microenvironment by inhibiting cancer-associated fibroblasts and facilitating the remodeling of the tumor vasculature system.Formula:C58H83NO17Color and Shape:SolidMolecular weight:1065.5661Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formula:C22H21N3O3Purity:99.99%Color and Shape:SolidMolecular weight:375.4204Katanin-IN-1
Katanin-IN-1 (122589735) is an effective inhibitor of katanin, and it holds potential for cancer research.Formula:C24H33N9O3Color and Shape:SolidMolecular weight:495.58
