Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 274 products of "Microtubule Associated"
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Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formula:C20H14ClNO2SPurity:99.05%Color and Shape:SolidMolecular weight:367.85Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.89Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99%Color and Shape:SolidMolecular weight:527.63Ref: TM-T15675
2mg35.00€5mg52.00€10mg66.00€25mg119.00€50mg230.00€100mg394.00€200mg532.00€1mL*10mM (DMSO)62.00€Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Purity:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.92 kDaZagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purity:> 95% - >95.0% (SDS-PAGE)Color and Shape:LiquidMolecular weight:145.3 kDaVerubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Ref: TM-T13298
5mg52.00€10mg73.00€25mg138.00€50mg200.00€100mg284.00€200mg411.00€1mL*10mM (DMSO)52.00€BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formula:C20H20O7Purity:96.57%Color and Shape:SolidMolecular weight:372.37Ref: TM-T14694
1mg79.00€5mg152.00€10mg215.00€25mg351.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)167.00€Anticancer agent 270
Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.Color and Shape:Odour SolidAnti-α-Tubulin Antibody, AF555 conjugate
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for theColor and Shape:SolidDiminutol
CAS:Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Formula:C19H26N6OSColor and Shape:SolidMolecular weight:386.51N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS:N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFormula:C24H18ClN3OPurity:99.93%Color and Shape:SoildMolecular weight:399.87Ref: TM-T60041
1mg109.00€5mg241.00€10mg355.00€25mg532.00€50mg745.00€100mg1,018.00€200mg1,378.00€1mL*10mM (DMSO)264.00€Tubulin polymerization-IN-47
CAS:Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancerFormula:C22H21N3O3Purity:99.64%Color and Shape:SoildMolecular weight:375.42Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formula:C22H21N3O3Purity:99.99%Color and Shape:SolidMolecular weight:375.42cis-trismethoxy Resveratrol
CAS:cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.
Formula:C17H18O3Purity:99.88%Color and Shape:SolidMolecular weight:270.32Trimethylcolchicinic acid
CAS:Trimethylcolchicinic acid is an orally available colchicine analog that binds to tubulin and inhibits its polymerization into microtubules,potential antitumor.Formula:C19H21NO5Purity:>99.99%Color and Shape:SoildMolecular weight:343.377-Epi-10-oxo-docetaxel
CAS:7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.86MT189
CAS:MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.Formula:C21H18FN3O2Purity:98.52%Color and Shape:SoildMolecular weight:363.38Dihydrocephalomannine
CAS:Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.Formula:C45H55NO14Purity:98%Color and Shape:SolidMolecular weight:833.928Vinflunine
CAS:Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.Formula:C45H54F2N4O8Color and Shape:SolidMolecular weight:816.93ER-076349
CAS:ER-076349 is a microtubule polymerization inhibitor that induces G2-M cell cycle arrest and disrupts mitotic spindles. This compound inhibits the growth of cancer cells and suppresses tumor growth in various human tumor xenograft mouse models. Additionally, ER-076349 is an analog of Halichondrin B.Formula:C40H58O12Color and Shape:SolidMolecular weight:730.88Epothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68Tubulin polymerization-IN-55
CAS:Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.Formula:C22H24N2O4Purity:98.68%Color and Shape:SoildMolecular weight:380.4410-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.874Aβ-IN-1 TFA
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.Formula:C37H50F3NO2Purity:99.82%Color and Shape:SoildMolecular weight:597.79Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cellFormula:C24H20FN3O3Color and Shape:SolidMolecular weight:417.43Microtubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
Formula:C83H127N25O34SPurity:98%Color and Shape:SolidMolecular weight:2051.11Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83Breast cancer targeting peptide 18-4
CAS:Breastcancertargeting peptide 18–4 is a keratin 1 (KRT1) receptor-targeting peptide with a dissociation constant (Kd) of 0.98 μM. Its amino acid sequence is WxEAAYQrFL, and it is an analogue of the P160 peptide. When covalently bonded with the anticancer peptide MccJ25, it significantly enhances MccJ25 uptake in breast cancer cells and boosts its anticancer efficacy. The IC50 values for this covalent compound are 14.2, 20, and 25 μM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR, respectively.Formula:C63H89N15O15Color and Shape:SolidMolecular weight:1296.47P160 peptide
CAS:P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor in breast cancer cells, with a Kd of approximately 1.1 μM. It shows significant potential for targeted drug delivery to breast cancer cells. P160 peptide enhances the cellular uptake and anticancer activity of the pro-apoptotic antimicrobial peptide MccJ25 (microcin J25). It is applicable in cancer research studies.Formula:C74H105N17O17SColor and Shape:SolidMolecular weight:1536.79Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFormula:C22H25NO6Color and Shape:SolidMolecular weight:399.44RI-AG03
RI-AG03 is an orally active peptide inhibitor capable of crossing the blood-brain barrier, targeting Tau aggregation. It effectively inhibits Tau aggregation in both in vivo and in vitro models, improving associated neurodegenerative and behavioral phenotypes. RI-AG03 is applicable in research on Tauopathies such as Alzheimer's disease.Formula:C104H189N49O22Color and Shape:SolidMolecular weight:2477.93Indicine N-oxide
CAS:Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.Formula:C15H25NO6Color and Shape:SolidMolecular weight:315.37Plecstatin-1 hydrochloride
Plecstatin-1 hydrochloride, an organoeuropium-containing anticancer agent, selectively targets the scaffolding protein plectin within tumor spheroids [1].Color and Shape:Odour SolidTubulin polymerization-IN-51
Tubulin Polymerization-IN-51 (compound 7u) serves as a tubulin polymerization inhibitor, exhibiting an IC50 range of 2.55 - 17.89μM against SK-Mel-28 cells, andColor and Shape:Odour SolidCeratamine A
CAS:Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.
Formula:C17H16Br2N4O2Purity:98%Color and Shape:SolidMolecular weight:468.14THK5351 (R enantiomer)
CAS:THK5351 R enantiomer is an R enantiomer of THK5351.Formula:C18H18FN3O2Color and Shape:SolidMolecular weight:327.35Tubulin polymerization-IN-49
Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cellFormula:C20H24O5Color and Shape:SolidMolecular weight:344.4Tubulin inhibitor 37
Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cellFormula:C16H10Cl2N6OColor and Shape:SolidMolecular weight:373.2Microtubule destabilizing agent-1
CAS:Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Formula:C22H26N4O4Color and Shape:SolidMolecular weight:410.47Modified MMAF
CAS:Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.Formula:C45H73N7O8Color and Shape:SolidMolecular weight:840.1Phomopsinamine
CAS:Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Formula:C32H43ClN6O8Color and Shape:SolidMolecular weight:675.17PM050489
CAS:PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.Formula:C31H44ClN3O7Color and Shape:SolidMolecular weight:606.15Tubulin inhibitor 21
Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.Formula:C28H25N3O4SColor and Shape:SolidMolecular weight:499.58TBL-100
TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.Color and Shape:Odour LiquidAntiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Formula:C18H15N3SColor and Shape:SolidMolecular weight:305.397Tubulin inhibitor 50
Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.Formula:C16H10ClFN2O2Color and Shape:SolidMolecular weight:316.04148Vinzolidine
CAS:Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.Formula:C48H58ClN5O9Color and Shape:SolidMolecular weight:884.46PROTAC tubulin-Degrader-1
PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.Color and Shape:Odour SolidCys-McMMAF
CAS:Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.Formula:C52H83N7O13SColor and Shape:SolidMolecular weight:1046.32Microtubule stabilizing agent-1
Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [Formula:C45H55NO13Color and Shape:SolidMolecular weight:817.92Anticancer agent 139
Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating highFormula:C16H12F3N3OColor and Shape:SolidMolecular weight:319.28Tubulin polymerization-IN-53
Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.Color and Shape:Odour SolidTubulin polymerization-IN-48
Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.Formula:C20H15Cl2N3OColor and Shape:SolidMolecular weight:384.26Deac-SS-Biotin
Deac-SS-Biotin is a potent antitumor compound that enters cells via biotin-mediated internalization.Color and Shape:Odour SolidColchicine, N-deacetyl-10-thio-
CAS:Colchicine, N-deacetyl-10-thio- is a biochemical.Formula:C20H23NO4SColor and Shape:SolidMolecular weight:373.47Pironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45Sudocetaxel
CAS:Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.Formula:C48H59NO16Color and Shape:SolidMolecular weight:905.98OncoFAP-GlyPro-MMAE
CAS:OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. It is composed of the FAP ligand OncoFAP, a microtubule inhibitor (MMAE), and a linker. OncoFAP-GlyPro-MMAE can be utilized in cancer research, including studies on renal cancer.Formula:C102H141F2N19O27SColor and Shape:SolidMolecular weight:2135.38Tubulin polymerization-IN-44
Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making itFormula:C19H15Cl2N3O3SColor and Shape:SolidMolecular weight:436.31T-900607
CAS:T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.
Formula:C14H10F5N3O4SPurity:98.84%Color and Shape:SolidMolecular weight:411.3Cy5-Paclitaxel
Cy5-Paclitaxel is a Cy5-labeled paclitaxel conjugate. Cy5 is a cyanine dye (with an approximate wavelength of 662 nm) utilized in molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization, causing mitotic arrest and apoptotic death. It also induces autophagy.Formula:C93H104N4O16Color and Shape:SolidMolecular weight:1533.847-Epi-docetaxel
CAS:7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.Formula:C43H53NO14Purity:98%Color and Shape:SolidMolecular weight:807.88Bifidenone
CAS:Bifidenone is an effective tubulin polymerization inhibitor.Formula:C21H26O5Color and Shape:SolidMolecular weight:358.43SPA107
CAS:SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.Formula:C31H48N4O4Color and Shape:SolidMolecular weight:540.74Tubulin Polymerization-IN-1 prodrug
CAS:Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.Formula:C22H23FN2O4Color and Shape:SolidMolecular weight:398.43TTBK1-IN-2
CAS:TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.
Formula:C18H13ClN4OPurity:99.83%Color and Shape:SoildMolecular weight:336.77Tubulin inhibitor 48
CAS:Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.Formula:C21H22N4OColor and Shape:SolidMolecular weight:346.43Larotaxel dihydrate
CAS:Larotaxel dihydrate possesses antineoplastic activity.Formula:C45H57NO16Purity:98%Color and Shape:SolidMolecular weight:867.93TNIR7-1A
CAS:TNIR7-1A is a fused cycloheptatriene-BODIPY derivative that is optimized for near-infrared (NIR) imaging characteristics (Ex/Em = 600/774 nm in PBS) and exhibits high affinity and specificity for neurofibrillary tangles (NFT) in vitro. Additionally, TNIR7-1A can effectively penetrate the blood-brain barrier.Formula:C23H20BF2N3Color and Shape:SolidMolecular weight:387.23Tubulin polymerization-IN-69
Tubulin polymerization-IN-69 (compound 6c) exhibits significant inhibition of microtubule assembly in vitro, with an inhibition rate of 78.3% and an IC50 value of 6.53 μM. It rapidly induces apoptosis and G2/M phase cell cycle arrest in MCF-7 cells.Color and Shape:Odour SolidALB-109564 dihydrochloride
CAS:ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.Formula:C47H62Cl2N4O9SPurity:98%Color and Shape:SolidMolecular weight:929.99T-808
CAS:T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.Formula:C17H19FN4Color and Shape:SolidMolecular weight:298.36KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structureFormula:C24H21NO5Color and Shape:SolidMolecular weight:403.43Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Formula:C18H18Na4O12P2Color and Shape:SolidMolecular weight:580.24Alestramustine
CAS:Alestramustine: a cancer drug that targets microtubules in estrogen receptor-positive cells, impeding cell division.Formula:C26H36Cl2N2O4Color and Shape:SolidMolecular weight:511.48Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formula:C45H54F2N4O8·xC4H6O6Purity:98%Color and Shape:SolidMolecular weight:967.02Ref: TM-T6722
2mgTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire1mL*10mM (DMSO)To inquireAADvac 1 TFA
AADvac 1 TFA is an active tau peptide vaccine utilized in Alzheimer's disease research. It is formed by conjugating the regulatory peptide 294KDNIKHVPGGGS305, which drives tau oligomerization, with keyhole limpet hemocyanin (KLH), and is formulated with aluminum hydroxide.Tubulin/PARP-IN-1
Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 μM for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.Formula:C19H13FO3Molecular weight:308.08487Tubulin inhibitor 45
Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.Formula:C19H18N2O2SMolecular weight:338.108920-O-Demethyl-AP3
CAS:20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.Formula:C31H41ClN2O9Color and Shape:SolidMolecular weight:621.12Anhydrovinblastine sulfate
Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.Formula:C46H60N4O16S2Molecular weight:988.34457Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFormula:C17H13ClN6OSColor and Shape:SolidMolecular weight:384.84Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Formula:C36H45ClN6O12Purity:98%Color and Shape:SolidMolecular weight:789.23Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Color and Shape:Odour Solidcolchiceine
CAS:colchiceine has a wide range of applications in life science related research.Formula:C21H23NO6Purity:99.38%Color and Shape:SolidMolecular weight:385.41Trifluralin
CAS:Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.Formula:C13H16F3N3O4Purity:99.84%Color and Shape:Yellow-Orange Crystalline SolidMolecular weight:335.28PhosTAC7
CAS:PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.Formula:C58H87ClN2O17Purity:98.96%Color and Shape:SolidMolecular weight:1119.77Avanbulin
CAS:Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.Formula:C20H17N7O2Color and Shape:SolidMolecular weight:387.39BSc3094
CAS:BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.Formula:C17H12N6O3SColor and Shape:SolidMolecular weight:380.38Amiprofos methyl
CAS:Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Formula:C11H17N2O4PSPurity:99.66%Color and Shape:SolidMolecular weight:304.30TTBK1-IN-1
CAS:TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.Formula:C18H19N5O2Color and Shape:SolidMolecular weight:337.38Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C26H31Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:504.45Oryzalin
CAS:Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.Formula:C12H18N4O6SPurity:99.86%Color and Shape:SolidMolecular weight:346.36Ombrabulin hydrochloride
CAS:Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells andFormula:C21H27ClN2O6Purity:98%Color and Shape:SolidMolecular weight:438.9Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Ref: TM-T6345
1mg34.00€5mg60.00€10mg73.00€25mg142.00€50mg253.00€100mg424.00€200mg605.00€1mL*10mM (DMSO)63.00€TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Formula:C19H18N2O2Purity:99.54%Color and Shape:SolidMolecular weight:306.364-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Formula:C10H12O3Purity:99.88%Color and Shape:White To Off-White PowderMolecular weight:180.2MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formula:C22H34O2Purity:97.024%Color and Shape:SolidMolecular weight:330.5N-Phenylbenzylamine
CAS:A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerizationFormula:C13H13NPurity:98.75%Color and Shape:Colorless To Pale Yellow Crystalline PowderMolecular weight:183.25Valecobulin
CAS:Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.Formula:C26H28N6O5SPurity:98%Color and Shape:SolidMolecular weight:536.6Vindesine sulfate
CAS:Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.Formula:C43H57N5O11SPurity:97.51%Color and Shape:Amorphous SolidMolecular weight:852Tau protein (592-597), Human TFA
Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.Formula:C36H63F3N10O11Purity:>99.99%Color and Shape:SolidMolecular weight:868.94Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formula:C12H15N3O3SPurity:97.29%Color and Shape:White To Off-White PowderMolecular weight:281.33Clanfenur
CAS:Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.Formula:C16H15ClFN3O2Purity:99.93%Color and Shape:SolidMolecular weight:335.76Ref: TM-T5448
1mg37.00€5mg81.00€10mg116.00€25mg188.00€50mg284.00€100mg395.00€200mg560.00€1mL*10mM (DMSO)92.00€Suprafenacine
CAS:Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces
Formula:C16H18N4OPurity:99.91%Color and Shape:SolidMolecular weight:282.34D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Formula:C16H13NO2Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:251.28LP-261
CAS:LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.Formula:C22H19N3O4SPurity:99.91%Color and Shape:SolidMolecular weight:421.47Ref: TM-T9595
1mg35.00€2mg50.00€5mg74.00€10mg113.00€25mg177.00€50mg334.00€100mg500.00€1mL*10mM (DMSO)82.00€Plinabulin
CAS:Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).Formula:C19H20N4O2Purity:98.69% - >99.99%Color and Shape:SolidMolecular weight:336.39Spastazoline
CAS:Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).Formula:C20H30N8Purity:99.23%Color and Shape:SolidMolecular weight:382.51Ref: TM-T8513
1mg34.00€5mg71.00€10mg105.00€25mg205.00€50mg306.00€100mg440.00€200mg612.00€1mL*10mM (DMSO)78.00€Parbendazole
CAS:Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.Formula:C13H17N3O2Purity:99.60%Color and Shape:Physical Description Crystals Or Fine White Powder (Ntp 1992)Molecular weight:247.29T807
CAS:T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).Formula:C16H10FN3Purity:99.72%Color and Shape:SolidMolecular weight:263.27Ref: TM-T19573
2mg47.00€5mg70.00€10mg107.00€25mg187.00€50mg323.00€100mg550.00€200mg758.00€500mg1,159.00€MMAD
CAS:MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).Formula:C41H66N6O6SPurity:99.25% - 99.91%Color and Shape:SolidMolecular weight:771.06Soblidotin
CAS:Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.Formula:C39H67N5O6Purity:99.89%Color and Shape:SolidMolecular weight:701.98Curvulin
CAS:Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.Formula:C12H14O5Purity:98.65%Color and Shape:SolidMolecular weight:238.24Ref: TM-T36850
1mg145.00€5mg319.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€1mL*10mM (DMSO)284.00€Estramustine
CAS:Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Formula:C23H31Cl2NO3Purity:98.09%Color and Shape:SolidMolecular weight:440.4Ref: TM-T20681
5mg44.00€10mg66.00€25mg119.00€50mg192.00€100mg313.00€200mg460.00€1mL*10mM (DMSO)52.00€NQTrp
CAS:NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.Formula:C21H16N2O4Purity:98.35%Color and Shape:SolidMolecular weight:360.36Posdinemab
CAS:Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].
Color and Shape:LiquidGosuranemab
CAS:Gosuranemab (BIIB092) is a humanised monoclonal antibody targeting N-terminal tau, inhibiting the propagation and aggregation of pathological tau protein.Purity:95% - 97.5% (SDS-PAGE); 95.2% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.93 kDa4-Desacetylvinblastine hydrazide
CAS:Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.Formula:C43H56N6O7Color and Shape:SolidMolecular weight:768.94ST-401
CAS:ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.Formula:C24H20N2OColor and Shape:SolidMolecular weight:352.43Tubulin polymerization-IN-2
CAS:Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.Formula:C17H12F2N2O2Color and Shape:SolidMolecular weight:314.29Centmitor-1
CAS:Centmitor-1 is a novel mitotic inducer that modulates the positive end of microtubules and reduces microtubule dynamics.Formula:C22H16BrN3O3Color and Shape:SolidMolecular weight:450.28CHM-1-P-Na
CAS:CHM-1-P-Na is used as a hydrophilic prodrug of CHM-1.Formula:C16H11FNNaO6PColor and Shape:SolidMolecular weight:386.227THK-5117
CAS:THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36CAY10701
CAS:CAY10701, a 7-deazahypoxanthine, impedes cell growth (GI50: 9-38 nM) while sparing normal fibroblasts (>1,500-fold), and shrinks mouse colorectal tumors.Formula:C24H19N3O2Color and Shape:SolidMolecular weight:381.43Cevipabulin fumarate
CAS:Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).Formula:C22H22ClF5N6O5Purity:98%Color and Shape:SolidMolecular weight:580.89OXi8007
CAS:OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.Formula:C26H24NNa2O10PColor and Shape:SolidMolecular weight:587.428Hydromethylthionine HBr
CAS:Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.Formula:C16H21Br2N3SColor and Shape:SolidMolecular weight:447.233Synstab A
CAS:Synstab A is a microtubule stabilizer.Formula:C15H13BrCl3N3O3SColor and Shape:SolidMolecular weight:501.61(S)-Dolaphenine hydrochloride
CAS:(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.Formula:C11H13ClN2SPurity:98%Color and Shape:SolidMolecular weight:240.75Tubulin polymerization-IN-7
CAS:Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.Formula:C28H24N4O6SColor and Shape:SolidMolecular weight:544.58Tubulin inhibitor 31
Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.Formula:C22H19NO2Color and Shape:SolidMolecular weight:329.39Deox B 7,4
CAS:Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.Formula:C18H18O5Color and Shape:SolidMolecular weight:314.33(R)-TTBK1-IN-1
CAS:(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.Formula:C18H19N5O2Color and Shape:SolidMolecular weight:337.38Tubulin polymerization-IN-25
CAS:Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.Formula:C24H18N2O3SColor and Shape:SolidMolecular weight:414.48Microtubule inhibitor 6
CAS:Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.Formula:C24H19FN2O5Color and Shape:SolidMolecular weight:434.42Tubulin polymerization-IN-15
CAS:Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].Formula:C18H17N3O4Color and Shape:SolidMolecular weight:339.35Tubulin polymerization-IN-20
CAS:Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.Formula:C25H24FNO5Color and Shape:SolidMolecular weight:437.46Tubulin inhibitor 18
CAS:"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."Formula:C22H26O5Color and Shape:SolidMolecular weight:370.44Tubulin/MMP-IN-1
Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.Formula:C38H44NO9PColor and Shape:SolidMolecular weight:689.73Tubulin polymerization-IN-18
CAS:Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.Formula:C25H25NO6Color and Shape:SolidMolecular weight:435.47Tubulin inhibitor 12
CAS:New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.Formula:C24H20N2OColor and Shape:SolidMolecular weight:352.43Tau tracer 1
CAS:Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.Formula:C34H23N5O2Color and Shape:SolidMolecular weight:533.591Tubulin inhibitor 29
CAS:Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.Formula:C12H8F2O2S2Color and Shape:SolidMolecular weight:286.32Tubulin polymerization-IN-30
CAS:Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.Formula:C22H25N5O3Color and Shape:SolidMolecular weight:407.47Iso-Fludelone
CAS:Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.Formula:C27H36F3NO6Color and Shape:SolidMolecular weight:527.57OSIP-486823
CAS:OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Formula:C29H28FNO4Purity:98.59%Color and Shape:SolidMolecular weight:473.54Sabeluzole
CAS:Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.Formula:C22H26FN3O2SPurity:98.51%Color and Shape:SolidMolecular weight:415.52Tau-aggregation and neuroinflammation-IN-1
CAS:Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Formula:C25H20N2O7Purity:99.85%Color and Shape:SolidMolecular weight:460.44SB26019
CAS:SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.Formula:C24H20O4Color and Shape:SolidMolecular weight:372.41O-GlcNAcase-IN-4
CAS:O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.Formula:C16H22FN5O3SColor and Shape:SolidMolecular weight:383.44AMXI-5001
CAS:AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.Formula:C25H20FN5O3Color and Shape:SolidMolecular weight:457.46Microtubule inhibitor 7
CAS:Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.Formula:C25H19FN2O5Color and Shape:SolidMolecular weight:446.43Tau protein aggregation-IN-1
CAS:Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disordersFormula:C17H11BrN2O2Color and Shape:SolidMolecular weight:355.19Tubulin polymerization-IN-16
CAS:Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.Formula:C24H27N5O5Color and Shape:SolidMolecular weight:465.5Antitumor agent-68
CAS:Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.Formula:C17H11NO2Color and Shape:SolidMolecular weight:261.27Tubulin polymerization-IN-36
CAS:Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35Neuroinflammatory-IN-3
CAS:Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.Formula:C19H19ClO3Color and Shape:SolidMolecular weight:330.81Cevipabulin
CAS:Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cellFormula:C18H18ClF5N6OPurity:99.53%Color and Shape:SolidMolecular weight:464.82Antitumor agent-71
CAS:Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.Formula:C26H31N5O4SColor and Shape:SolidMolecular weight:509.62Tubulin polymerization-IN-10
CAS:Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43IQTub4P
CAS:IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).Formula:C19H18NNa2O8PColor and Shape:SolidMolecular weight:465.305Tubulin polymerization-IN-42
CAS:Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].Formula:C22H21NO5Color and Shape:SolidMolecular weight:379.41CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Formula:C14H9N3OPurity:98.38%Color and Shape:SolidMolecular weight:235.24Ref: TM-T10704
1mg73.00€5mg161.00€10mg245.00€25mg480.00€50mg735.00€100mg999.00€1mL*10mM (DMSO)172.00€Alyssin
CAS:Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.Formula:C7H13NOS2Purity:98%Color and Shape:SolidMolecular weight:191.31Tubulin polymerization-IN-21
CAS:Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.Formula:C30H29NO7Color and Shape:SolidMolecular weight:515.55OX01914
CAS:OX01914 is a soluble modulator to increase utrophin in DMD studies, EC50 20.5 μM.Formula:C17H14N4OColor and Shape:SolidMolecular weight:290.32Microtubule inhibitor 5
CAS:Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.Formula:C22H15FN2O4Color and Shape:SolidMolecular weight:390.36Tubulin polymerization-IN-39
Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.Formula:C21H21N5O5Color and Shape:SolidMolecular weight:423.42Tubulin polymerization-IN-37
CAS:Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37Denibulin HCl
CAS:Denibulin (MN-029) disrupts tumor blood vessels by inhibiting microtubule assembly, enhancing radiation and cisplatin efficacy.Formula:C18H20ClN5O3SColor and Shape:SolidMolecular weight:421.9Tubulin inhibitor 28
CAS:Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.Formula:C12H8Br2S2Color and Shape:SolidMolecular weight:376.13TOK-8801
CAS:TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.Formula:C17H21N3OSPurity:99.97%Color and Shape:SolidMolecular weight:315.43MT-7
CAS:MT-7 is a tubulin polymerization inhibitor.Formula:C22H17N3O2Purity:98%Color and Shape:SolidMolecular weight:355.39Tubulin inhibitor 7
CAS:Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (Formula:C21H14N2O4Purity:98%Color and Shape:SolidMolecular weight:358.35Microtubule inhibitor 1
CAS:Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).Formula:C21H19NO3Purity:98%Color and Shape:SolidMolecular weight:333.38Alyssin, (R)-
CAS:Alyssin, (R)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Color and Shape:SolidMolecular weight:191.31Cemadotin hydrochloride
CAS:Cemadotin hydrochloride (LU103793) is a synthetic mitosis inhibitor derived from Dolastatin 15 for treating solid tumors.Formula:C35H57ClN6O5Color and Shape:SolidMolecular weight:677.33Alyssin, (S)-
CAS:Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Color and Shape:SolidMolecular weight:191.31Anticancer agent 48
CAS:Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.Formula:C26H25N3O4Color and Shape:SolidMolecular weight:443.49Tubulin inhibitor 27
CAS:DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.Formula:C21H19NO4Color and Shape:SolidMolecular weight:349.38Microtubule inhibitor 4
CAS:Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).Formula:C25H23FN4O3Color and Shape:SolidMolecular weight:446.47Mivobulin
CAS:Mivobulin is an inhibitor of tubulin .Formula:C17H19N5O2Purity:98%Color and Shape:SolidMolecular weight:325.37Tubulozole
CAS:Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.Formula:C23H23Cl2N3O4SPurity:98%Color and Shape:SolidMolecular weight:508.42BNC105P
CAS:BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.Formula:C20H21O10PColor and Shape:SolidMolecular weight:452.3485Sirt1/2-IN-1
CAS:Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.Formula:C22H13ClN2OS2Color and Shape:SolidMolecular weight:420.93Tubulin polymerization-IN-29
CAS:Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.Formula:C25H20FNO6Color and Shape:SolidMolecular weight:449.43isoCA-4
CAS:isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].Formula:C18H20O5Color and Shape:SolidMolecular weight:316.35Amphethinile
CAS:Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.Formula:C15H11N3SPurity:98%Color and Shape:SolidMolecular weight:265.33IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purity:98%Color and Shape:SolidMolecular weight:179.26DHNQ
CAS:DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).Formula:C18H14N2OColor and Shape:SolidMolecular weight:274.32D011-2120
CAS:D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.Formula:C17H15NO3Purity:98%Color and Shape:SolidMolecular weight:281.31DAT1
CAS:DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.Formula:C17H15N3O2SPurity:98%Color and Shape:SolidMolecular weight:325.38Acodazole
CAS:Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.Formula:C20H19N5OPurity:98%Color and Shape:SolidMolecular weight:345.4Acodazole hydrochloride
CAS:Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.Formula:C20H20ClN5OPurity:98%Color and Shape:SolidMolecular weight:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Formula:C15H11FN4OSPurity:98%Color and Shape:SolidMolecular weight:314.34Anticancer agent 60
CAS:Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.Formula:C27H33N5O4SColor and Shape:SolidMolecular weight:523.65MG-2119
CAS:MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.Formula:C27H29N5O4Color and Shape:SolidMolecular weight:487.55Aha1/Hsp90-IN-1
CAS:Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.Formula:C22H17F3N4O2Color and Shape:SolidMolecular weight:426.39Tubulin polymerization-IN-27
CAS:Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.Formula:C22H20N2O2Color and Shape:SolidMolecular weight:344.41
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