c-Myc
c-Myc inhibitors target the c-Myc protein, a transcription factor that plays a pivotal role in cell growth, proliferation, and apoptosis. c-Myc regulates the expression of numerous genes involved in the cell cycle and is often overexpressed in various cancers, leading to uncontrolled cell proliferation and tumor growth. Inhibiting c-Myc can disrupt these processes, inducing cell cycle arrest and apoptosis in cancer cells. c-Myc inhibitors are important tools in cancer research and therapeutic development. At CymitQuimica, we offer a wide range of high-quality c-Myc inhibitors to support your research in oncology, cell cycle regulation, and transcriptional control.
Found 76 products of "c-Myc"
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MYCi975
CAS:MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.Formula:C25H16Cl2F6N2O2Purity:99.3% - 99.82%Color and Shape:SolidMolecular weight:561.3FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formula:C15H13ClFNPurity:98.3% - 99.17%Color and Shape:SolidMolecular weight:261.72Ref: TM-T11285
1mg59.00€2mg85.00€5mg116.00€10mg187.00€25mg331.00€50mg512.00€100mg740.00€500mg1,415.00€Eragidomide
CAS:Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.Formula:C22H18ClF2N3O4Purity:97.51% - 99.63%Color and Shape:SolidMolecular weight:461.85Ref: TM-T10765
1mg38.00€5mg82.00€10mg133.00€25mg269.00€50mg442.00€100mg595.00€200mg802.00€1mL*10mM (DMSO)84.00€Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurity:99.52%Color and Shape:SolidMolecular weight:333.43MYCi361
CAS:MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).Formula:C26H16ClF9N2O2Purity:99.52%Color and Shape:SolidMolecular weight:594.86Ceramides Mixture
CAS:Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.Formula:C36H71NO4Purity:98%Color and Shape:SolidMolecular weight:581.967MYCMI-6
CAS:MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.Formula:C20H19N7OPurity:99.23%Color and Shape:SolidMolecular weight:373.41Ref: TM-T12134
1mg71.00€5mg152.00€10mg222.00€25mg358.00€50mg512.00€100mg707.00€200mg973.00€500mg1,431.00€KJ Pyr 9
CAS:KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formula:C22H15N3O4Purity:99.56% - ≥98%Color and Shape:SolidMolecular weight:385.37Ref: TM-T15665
2mg37.00€5mg54.00€10mg77.00€25mg138.00€50mg264.00€100mg482.00€200mg647.00€500mg1,009.00€1mL*10mM (DMSO)59.00€FIDAS-3
CAS:FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activitiesFormula:C16H15F2NPurity:97.75%Color and Shape:SolidMolecular weight:259.29Ref: TM-T11284
5mg49.00€10mg73.00€25mg127.00€50mg182.00€100mg264.00€200mg354.00€1mL*10mM (DMSO)48.00€APTO-253
CAS:APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.Formula:C22H14FN5Purity:98.73%Color and Shape:SolidMolecular weight:367.38Ref: TM-T10352
1mg40.00€2mg52.00€5mg75.00€10mg96.00€25mg170.00€50mg255.00€100mg371.00€1mL*10mM (DMSO)84.00€PROTAC MTP3 degrade-1
PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.Formula:C44H38N6O8Color and Shape:SolidMolecular weight:778.27511c-Myc inhibitor 10
CAS:c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.Formula:C28H38N6O3Color and Shape:SolidMolecular weight:506.64Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.Formula:C13H20N2O6Color and Shape:SolidMolecular weight:300.308c-Myc inhibitor 7
CAS:c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.Formula:C35H30N6O5Color and Shape:SoildMolecular weight:614.65H122
H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)Formula:C45H45ClFN5O8Color and Shape:SolidMolecular weight:838.319VTX-0811
VTX-0811 is a human IgG4 monoclonal antibody (mAb) that targets PSGL1/CD162. It modulates immune signaling pathways by enhancing TNF-α/NF-κB and chemokine-mediated signaling while reducing oxidative phosphorylation, fatty acid metabolism, and Myc signaling. VTX-0811 increases the proportion of CD8+ T cells among infiltrating T cells and exhibits antitumor activity in humanized mouse PDX models of melanoma.Color and Shape:Odour LiquidVGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.Formula:C121H218N46O32Molecular weight:2827.68453RA-V
RA-V is a natural product that can be used as a reference standard.Formula:C160H202N24O41Color and Shape:SolidMolecular weight:3117.5c-Myc inhibitor 13
c-Myc inhibitor13 (compound A6) is an inhibitor of c-MYC transcription. It selectively stabilizes c-MYCG4 and inhibits G4-related c-MYC transcription.Formula:C30H39N9OMolecular weight:541.32776Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Color and Shape:Odour Solid
