DYRK
DYRK (Dual-specificity Tyrosine Phosphorylation-regulated Kinase) inhibitors are compounds that target the DYRK family of kinases, which are involved in cell cycle regulation, neuronal development, and apoptosis. DYRK kinases have dual specificity, meaning they can phosphorylate both tyrosine and serine/threonine residues. Inhibiting DYRK kinases can affect various cellular processes, including cell cycle progression and differentiation. DYRK inhibitors are important tools in research on cancer, neurodegenerative diseases, and cell signaling. At CymitQuimica, we offer a selection of high-quality DYRK inhibitors to support your research in cell cycle control, neurobiology, and therapeutic development.
Found 48 products of "DYRK"
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AZ-Dyrk1B-33
CAS:<p>AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.</p>Formula:C19H16N4Purity:99.91%Color and Shape:SolidMolecular weight:300.36BT173
CAS:<p>BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.</p>Formula:C18H12BrN3O2Purity:98.247%Color and Shape:SolidMolecular weight:382.21GSK-626616
CAS:<p>GSK-626616: strong, oral DYRK3 inhibitor (IC50: 0.7 nM), affects DYRK family, may treat anemia.</p>Formula:C18H10Cl2N4OSPurity:98.27%Color and Shape:SolidMolecular weight:401.27CLK1-IN-3
CAS:<p>Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A.</p>Formula:C24H23FN6OPurity:98.46% - 99.76%Color and Shape:SoildMolecular weight:430.48Leucettine L41
CAS:<p>Leucettine L41 (LeucettineL41) is an inhibitor of DYRKs/CLKs, preferentially targeting DYRK1A, and inhibits DYRK2.</p>Formula:C17H13N3O3Purity:99.08%Color and Shape:SolidMolecular weight:307.3GNF2133
CAS:<p>GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.</p>Formula:C24H30N6O2Purity:98.51%Color and Shape:SolidMolecular weight:434.53Protein kinase inhibitors 1 hydrochloride
CAS:<p>Protein Kinase Inhibitors 1 Hydrochloride effectively inhibits HIPK2, demonstrating high potency with IC50 values of 136 nM for HIPK1 and 74 nM for HIPK2,</p>Formula:C18H18ClN5O3SColor and Shape:SolidMolecular weight:419.88Mirk-IN-1
CAS:<p>Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively).</p>Formula:C23H17Cl2N5O4Purity:98%Color and Shape:SolidMolecular weight:498.32ML167
CAS:<p>ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.</p>Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36GNF4877
CAS:<p>GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.</p>Formula:C25H27FN6O4Purity:98.68% - 99.40%Color and Shape:SolidMolecular weight:494.52Harmine
CAS:<p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>Formula:C13H12N2OPurity:98.29% - 99.92%Color and Shape:Off-White SolidMolecular weight:212.25LDN-192960 hydrochloride
CAS:<p>LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.</p>Formula:C18H22Cl2N2O2SPurity:98%Color and Shape:SolidMolecular weight:401.35Harmine hydrochloride
CAS:<p>Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.</p>Formula:C13H13ClN2OPurity:99.61% - >99.99%Color and Shape:Yellow To Slightly Green Crystalline PowderMolecular weight:248.71ID-8
CAS:<p>ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.</p>Formula:C16H14N2O4Purity:99.32%Color and Shape:SolidMolecular weight:298.29LDN-192960
CAS:<p>LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).</p>Formula:C18H20N2O2SPurity:98.01% - 99.51%Color and Shape:SolidMolecular weight:328.43AZ191
CAS:<p>AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor.</p>Formula:C24H27N7OPurity:98.04% - 99.65%Color and Shape:SolidMolecular weight:429.52Protein kinase inhibitors 1
CAS:<p>Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.</p>Formula:C18H17N5O3SPurity:98%Color and Shape:SolidMolecular weight:383.42ILK-IN-3
CAS:<p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>Formula:C10H12N6OPurity:99.69%Color and Shape:SolidMolecular weight:232.24GNF2133 hydrochloride
CAS:<p>GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.</p>Formula:C24H31ClN6O2Color and Shape:SolidMolecular weight:471.02-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi
CAS:<p>2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.</p>Formula:C6H6N4OPurity:99.21% - 99.42%Color and Shape:SolidMolecular weight:150.14
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