DYRK
DYRK (Dual-specificity Tyrosine Phosphorylation-regulated Kinase) inhibitors are compounds that target the DYRK family of kinases, which are involved in cell cycle regulation, neuronal development, and apoptosis. DYRK kinases have dual specificity, meaning they can phosphorylate both tyrosine and serine/threonine residues. Inhibiting DYRK kinases can affect various cellular processes, including cell cycle progression and differentiation. DYRK inhibitors are important tools in research on cancer, neurodegenerative diseases, and cell signaling. At CymitQuimica, we offer a selection of high-quality DYRK inhibitors to support your research in cell cycle control, neurobiology, and therapeutic development.
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AZ-Dyrk1B-33
CAS:1679330-37-0
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 …
Formula:
C19H16N4
Purity:
99.99%
Color and Shape:
Solid
Molecular weight:
300.36
Ref: TM-T14364
| 1mg | 45.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 293.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 593.00 € | ||
| 200mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
GSK-626616
CAS:1025821-33-3
GSK-626616: strong, oral DYRK3 inhibitor (IC50: 0.7 nM), affects DYRK family, may treat anemia.
Formula:
C18H10Cl2N4OS
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
401.27
Ref: TM-T15422
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 508.00 € | ||
| 100mg | 733.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CLK1-IN-3
CAS:2922550-28-3
Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of …
Formula:
C24H23FN6O
Purity:
99.79%
Color and Shape:
Soild
Molecular weight:
430.48
Ref: TM-T72039
| 1mg | 102.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 398.00 € | ||
| 25mg | 810.00 € | ||
| 50mg | 1,346.00 € | ||
| 100mg | 2,154.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
GNF2133
CAS:2561414-56-8
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 …
Formula:
C24H30N6O2
Purity:
98.11%
Color and Shape:
Liquid
Molecular weight:
434.53
Ref: TM-T40187
| 1mg | 125.00 € | ||
| 5mg | 300.00 € | ||
| 10mg | 453.00 € | ||
| 25mg | 757.00 € | ||
| 50mg | 1,124.00 € | ||
| 100mg | 1,606.00 € | ||
| 1mL*10mM (DMSO) | 344.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Harmine hydrochloride
CAS:343-27-1
Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.
Formula:
C13H13ClN2O
Purity:
100% - 99.45%
Color and Shape:
Yellow To Slightly Green Crystalline Powder
Molecular weight:
248.71
Ref: TM-T2811
| 50mg | 53.00 € | ||
| 100mg | 76.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZ191
CAS:1594092-37-1
AZ191(IC50 of 17 nM) is an effective and specific DYRK1B inhibitor.
Formula:
C24H27N7O
Purity:
98.04% - 99.65%
Color and Shape:
Solid
Molecular weight:
429.52
Ref: TM-T6257
| 2mg | 46.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 252.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LDN-192960
CAS:184582-62-5
LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).
Formula:
C18H20N2O2S
Purity:
98.01% - 99.51%
Color and Shape:
Solid
Molecular weight:
328.43
Ref: TM-TQ0111
| 1mg | 130.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 496.00 € | ||
| 50mg | 722.00 € | ||
| 100mg | 1,013.00 € | ||
| 500mg | 2,018.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Harmine
CAS:442-51-3
Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.
Formula:
C13H12N2O
Purity:
98.29% - 99.92%
Color and Shape:
Off-White Solid
Molecular weight:
212.25
Ref: TM-T1711
| 1g | 77.00 € | ||
| 100mg | 36.00 € | ||
| 500mg | 59.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Protein kinase inhibitors 1
CAS:1365986-44-2
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 …
Formula:
C18H17N5O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
383.42
Ref: TM-T4636
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GNF4877
CAS:2041073-22-5
GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.
Formula:
C25H27FN6O4
Purity:
98.63% - 99.40%
Color and Shape:
Solid
Molecular weight:
494.52
Ref: TM-T11447
| 1mg | 123.00 € | ||
| 5mg | 291.00 € | ||
| 10mg | 507.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,278.00 € | ||
| 100mg | 1,725.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML167
CAS:1285702-20-6
ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
Formula:
C19H17N3O3
Purity:
100% - 98.85%
Color and Shape:
Solid
Molecular weight:
335.36
Ref: TM-T2670
| 2mg | 34.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 338.00 € | ||
| 200mg | 480.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ID-8
CAS:147591-46-6
ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
Formula:
C16H14N2O4
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
298.29
Ref: TM-T2431
| 5mg | 47.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 228.00 € | ||
| 200mg | 337.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CLK-IN-T3
CAS:2109805-56-1
CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and …
Formula:
C28H30N6O2
Purity:
98.37%
Color and Shape:
Solid
Molecular weight:
482.58
Ref: TM-T14980
| 1mg | 58.00 € | ||
| 2mg | 82.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 435.00 € | ||
| 50mg | 640.00 € | ||
| 100mg | 909.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ProINDY
CAS:719277-30-2
ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down …
Formula:
C14H15NO3S
Purity:
97.19%
Color and Shape:
Solid
Molecular weight:
277.34
Ref: TM-T23186
| 1mg | 89.00 € | ||
| 5mg | 210.00 € | ||
| 10mg | 312.00 € | ||
| 25mg | 523.00 € | ||
| 50mg | 728.00 € | ||
| 100mg | 1,013.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
YK-2-69
CAS:2619846-89-6
YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.
Formula:
C25H27FN8OS
Purity:
98.45% - 99.57%
Color and Shape:
Liquid
Molecular weight:
506.6
Ref: TM-T69564
| 1mg | 274.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
INDY
CAS:1169755-45-6
INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and …
Formula:
C12H13NO2S
Purity:
98.15%
Color and Shape:
Solid
Molecular weight:
235.3
Ref: TM-T15579
| 5mg | 60.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 110.00 € | ||
| 50mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
ML 315
CAS:1440251-53-5
ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the …
Formula:
C18H13Cl2N3O2
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
374.22
Ref: TM-T36707
| 1mg | 49.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 540.00 € | ||
| 100mg | 771.00 € | ||
| 500mg | 1,546.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
DYRKs-IN-2
CAS:1386980-04-6
DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM …
Formula:
C32H38ClN9O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
632.16
Ref: TM-T11133
| 25mg | 1,967.00 € | ||
| 50mg | 2,592.00 € | ||
| 100mg | 3,450.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
DYRKs-IN-1
CAS:1387090-01-8
DYRKs-IN-1 has antitumor activity.
Formula:
C30H30ClN7O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
588.06
Ref: TM-T11132
| 25mg | 2,662.00 € | ||
| 50mg | 3,533.00 € | ||
| 100mg | 4,860.00 € |
Estimated delivery in United States, on Wednesday 5 Mar 2025
