Wee1

Wee1 inhibitors target the Wee1 kinase, a key regulator of the G2/M checkpoint in the cell cycle. Wee1 controls the timing of mitosis by inhibiting cyclin-dependent kinases (CDKs) to prevent premature entry into mitosis. Inhibiting Wee1 can lead to the abrogation of the G2/M checkpoint, forcing cells with damaged DNA to enter mitosis prematurely, often resulting in cell death. This makes Wee1 inhibitors particularly useful in cancer therapy, especially in combination with DNA-damaging agents. At CymitQuimica, we provide a selection of high-quality Wee1 inhibitors to support your research in cell cycle control, DNA damage response, and cancer treatment.