Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2612 products of "Chromatin/Epigenetics"
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AK-1
CAS:AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formula:C19H21N3O5SPurity:98.32% - 99.44%Color and Shape:SolidMolecular weight:403.45SHR0302
CAS:SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Formula:C18H22N8O2SPurity:99.11%Color and Shape:SolidMolecular weight:414.48Ref: TM-T9195
1mg80.00€5mg183.00€10mg298.00€25mg512.00€50mg817.00€100mg1,311.00€1mL*10mM (DMSO)167.00€Nudifloramide
CAS:Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).Formula:C7H8N2O2Purity:99.7% - ≥95%Color and Shape:SolidMolecular weight:152.15Rucaparib Phosphate
CAS:Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.Formula:C19H18FN3O·H3PO4Purity:99.37%Color and Shape:SolidMolecular weight:421.36Ref: TM-T6127
1mg35.00€2mg50.00€5mg74.00€10mg109.00€25mg178.00€50mg235.00€100mg371.00€200mg553.00€1mL*10mM (DMSO)74.00€Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formula:C20H27N7O3SPurity:98.74% - 99.49%Color and Shape:SolidMolecular weight:445.54Ref: TM-T2487
1mg42.00€2mg52.00€5mg74.00€10mg101.00€25mg175.00€50mg268.00€100mg409.00€200mg573.00€500mg888.00€1mL*10mM (DMSO)81.00€ORY1001
CAS:ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.Formula:C15H22N2·2HClPurity:99.85% - 99.96%Color and Shape:SolidMolecular weight:303.27Ref: TM-T6922
1mg56.00€2mg79.00€5mg127.00€10mg221.00€25mg427.00€50mg625.00€100mg889.00€500mg1,783.00€1mL*10mM (DMSO)127.00€Citarinostat
CAS:ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.Formula:C24H26ClN5O3Purity:98.06% - 99.06%Color and Shape:SolidMolecular weight:467.95Ruxolitinib (S enantiomer)
CAS:Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formula:C17H18N6Purity:99.37% - 99.79%Color and Shape:SolidMolecular weight:306.36M344
CAS:M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.Formula:C16H25N3O3Purity:98.18%Color and Shape:SolidMolecular weight:307.39Bobcat339
CAS:Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formula:C16H12ClN3OPurity:97.79% - 98.76%Color and Shape:SolidMolecular weight:297.74CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46Thiomyristoyl
CAS:Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.Formula:C34H51N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:581.85Ref: TM-T3447
1mg54.00€2mg73.00€5mg92.00€10mg117.00€25mg215.00€50mg360.00€100mg537.00€1mL*10mM (DMSO)117.00€Momelotinib HCl
CAS:Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formula:C23H24Cl2N6O2Color and Shape:SolidMolecular weight:487.38Tucidinostat
CAS:Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.Formula:C22H19FN4O2Purity:97.01% - 99.95%Color and Shape:SolidMolecular weight:390.41Ref: TM-T4481
5mg60.00€10mg95.00€25mg159.00€50mg250.00€100mg399.00€200mg558.00€500mg832.00€1mL*10mM (DMSO)60.00€A1874
CAS:A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.
Formula:C58H62Cl3F2N9O7SPurity:99.52%Color and Shape:SolidMolecular weight:1173.59JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg48.00€5mg100.00€10mg155.00€25mg268.00€50mg432.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)94.00€Apabetalone
CAS:Apabetalone (RVX000222) , an effective BET bromodomain inhibitor, has been investigated for the treatment of diabetes, atherosclerosis, and coronary arteryFormula:C20H22N2O5Purity:98.08% - ≥98%Color and Shape:SolidMolecular weight:370.4LMK-235
CAS:LMK-235 is a potent HDAC inhibitor, and is used in cancer research.Formula:C15H22N2O4Purity:98.18% - 99.68%Color and Shape:SolidMolecular weight:294.35Ref: TM-T6061
5mg52.00€10mg74.00€25mg132.00€50mg222.00€100mg403.00€200mg593.00€500mg888.00€1mL*10mM (DMSO)49.00€653-47 hydrochloride
CAS:653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).Formula:C20H20Cl2N2O3Purity:99.14%Color and Shape:SolidMolecular weight:407.29Ref: TM-T8890
1mg87.00€5mg177.00€10mg334.00€25mg567.00€50mg807.00€100mg1,099.00€500mg2,205.00€1mL*10mM (DMSO)203.00€PKC-θ inhibitor hcl
CAS:PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).Formula:C20H26ClF3N6O3Purity:98.93%Color and Shape:SolidMolecular weight:490.91Ref: TM-T5817
1mg88.00€2mg114.00€5mg220.00€10mg356.00€25mg595.00€50mg848.00€100mg1,153.00€500mg2,305.00€SIS17
CAS:SIS17: Potent, selective HDAC11 inhibitor (IC50: 0.83 μM), blocks serine hydroxymethyl transferase 2 demyristoylation, spares other HDACs.Formula:C21H38N2OSPurity:98.22%Color and Shape:SolidMolecular weight:366.6Darovasertib
CAS:Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Formula:C22H23F3N8OPurity:98.72% - ≥95%Color and Shape:SolidMolecular weight:472.47GSK199
CAS:GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).Formula:C24H29ClN6O2Purity:99.44%Color and Shape:SolidMolecular weight:468.98Ref: TM-T8861
1mg62.00€5mg133.00€10mg215.00€25mg351.00€50mg494.00€100mg665.00€200mg893.00€1mL*10mM (DMSO)156.00€Remetinostat
CAS:Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cellFormula:C16H21NO6Purity:98.67%Color and Shape:SolidMolecular weight:323.34CBP/EP300-IN-1
CAS:CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.Formula:C23H23FN2O5Purity:99.05%Color and Shape:SolidMolecular weight:426.44Ref: TM-T7264
1mg46.00€2mg62.00€5mg92.00€10mg152.00€25mg250.00€50mg353.00€100mg502.00€200mg682.00€1mL*10mM (DMSO)100.00€Nicotinamide riboside chloride
CAS:NR, also SRT647, is a B3 vitamin form; precursor to NAD+.Formula:C11H15ClN2O5Purity:98.92% - 99.86%Color and Shape:SolidMolecular weight:290.7Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurity:99.53%Color and Shape:White Crystalline SolidMolecular weight:364.29Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:98% - >99.99%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g583.00€5mg49.00€10mg62.00€25mg78.00€50mg92.00€100mg138.00€200mg215.00€500mg395.00€1mL*10mM (DMSO)56.00€EX229
CAS:EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.Formula:C24H18ClN3O3Purity:99.20% - 99.36%Color and Shape:SolidMolecular weight:431.87Ref: TM-TQ0028
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg210.00€50mg356.00€100mg535.00€1mL*10mM (DMSO)80.00€6-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:98.75% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59GSK620
CAS:GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.Formula:C18H19N3O3Purity:99.42% - 99.88%Color and Shape:SolidMolecular weight:325.36Ref: TM-T9020
2mg34.00€5mg49.00€10mg73.00€25mg136.00€50mg212.00€100mg314.00€200mg467.00€1mL*10mM (DMSO)87.00€WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formula:C39H38F3N7O5Purity:99.41%Color and Shape:SolidMolecular weight:741.76Ref: TM-T9219
1mg38.00€2mg50.00€5mg84.00€10mg130.00€25mg250.00€50mg396.00€100mg585.00€1mL*10mM (DMSO)93.00€Pamiparib
CAS:Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.Formula:C16H15FN4OPurity:99.69%Color and Shape:SolidMolecular weight:298.31MS37452
CAS:MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).Formula:C22H26N2O5Purity:99.39%Color and Shape:SolidMolecular weight:398.45Ref: TM-T21767
5mg49.00€10mg84.00€25mg166.00€50mg289.00€100mg500.00€500mg1,063.00€1mL*10mM (DMSO)54.00€EPZ005687
CAS:EPZ005687 is a potent and selective inhibitor of EZH2.Formula:C32H37N5O3Purity:97.06% - 99.64%Color and Shape:SolidMolecular weight:539.67MC1568
CAS:MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B.Formula:C17H15FN2O3Purity:89.82% - ≥95%Color and Shape:SolidMolecular weight:314.31Fluzoparib
CAS:Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.Formula:C22H16F4N6O2Purity:98.53% - 99.63%Color and Shape:SolidMolecular weight:472.4Ref: TM-T8806
1mg60.00€2mg88.00€5mg124.00€10mg197.00€25mg389.00€50mg565.00€100mg822.00€500mg1,681.00€1mL*10mM (DMSO)145.00€HDAC8-IN-1
CAS:MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.Formula:C22H19NO3Purity:97.13% - 99.19%Color and Shape:SolidMolecular weight:345.39Ref: TM-T7082
1mg34.00€5mg63.00€10mg95.00€25mg172.00€50mg259.00€100mg330.00€200mg467.00€1mL*10mM (DMSO)70.00€YF-2
CAS:YF-2 activates histone acetyltransferases (H3, CBP, PCAF, GCN5) across the blood-brain barrier; EC50s: 2.75-49.31 μM.Formula:C20H22ClF3N2O3Purity:99.33%Color and Shape:SolidMolecular weight:430.85BCI-121
CAS:BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.Formula:C14H18BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:340.22Baricitinib
CAS:Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.Formula:C16H17N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:371.42Ref: TM-T2485
5mg48.00€10mg70.00€25mg95.00€50mg109.00€100mg137.00€200mg178.00€500mg295.00€1mL*10mM (DMSO)65.00€Tofacitinib Citrate
CAS:Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).Formula:C22H28N6O8Purity:99.19% - 99.75%Color and Shape:SolidMolecular weight:504.49SGC2085 HCl
CAS:SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.Formula:C19H24N2O2·HClPurity:99.91%Color and Shape:SolidMolecular weight:348.87Ref: TM-T4013
1mg93.00€2mg150.00€5mg190.00€10mg343.00€25mg567.00€50mg825.00€100mg1,130.00€1mL*10mM (DMSO)244.00€GSK-J1
CAS:GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.Formula:C22H23N5O2Purity:99.23% - 99.67%Color and Shape:SolidMolecular weight:389.45CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formula:C19H15N3O2Purity:96.14% - 99.16%Color and Shape:SolidMolecular weight:317.34Ref: TM-T3684
1mg38.00€2mg50.00€5mg84.00€10mg120.00€25mg236.00€50mg356.00€100mg537.00€1mL*10mM (DMSO)77.00€DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.Formula:C21H29Cl3N4OPurity:98%Color and Shape:SolidMolecular weight:459.84INCB-057643
CAS:INCB057643 is a potent, selective and orally bioavailable BET inhibitor.Formula:C20H21N3O5SPurity:99.5%Color and Shape:SolidMolecular weight:415.46Ref: TM-T5417
1mg39.00€5mg86.00€10mg133.00€25mg231.00€50mg349.00€100mg475.00€200mg652.00€1mL*10mM (DMSO)95.00€WIKI4
CAS:WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).Formula:C29H23N5O3SPurity:99.6% - 99.71%Color and Shape:SolidMolecular weight:521.59Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formula:C21H22NO4Purity:96.28% - 99.49%Color and Shape:SolidMolecular weight:352.4BYK204165
CAS:BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)Formula:C15H12N2O2Purity:99.61%Color and Shape:SolidMolecular weight:252.27Ref: TM-T7896
1mg44.00€5mg66.00€10mg90.00€25mg167.00€50mg236.00€100mg349.00€200mg512.00€1mL*10mM (DMSO)73.00€PJ34 hydrochloride
CAS:PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.Formula:C17H18ClN3O2Purity:98.87% - ≥95%Color and Shape:SolidMolecular weight:331.8Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formula:C21H22ClNO4Purity:97.9% - 99.47%Color and Shape:SolidMolecular weight:387.86Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formula:C27H36N6O3SPurity:97.31% - 99.96%Color and Shape:SolidMolecular weight:524.68Ref: TM-T1995
1g592.00€5mg50.00€10mg65.00€50mg107.00€100mg127.00€200mg205.00€500mg447.00€1mL*10mM (DMSO)54.00€BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formula:C28H39N7O3Purity:98% - 99.88%Color and Shape:SolidMolecular weight:521.65Ref: TM-T6173
1mg43.00€2mg56.00€5mg93.00€10mg98.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)92.00€5,7-Dihydroxychromone
CAS:1.Formula:C9H6O4Purity:99.76% - ≥95%Color and Shape:SolidMolecular weight:178.14Ref: TM-T5S1805
1mg44.00€5mg84.00€10mg119.00€25mg197.00€50mg294.00€100mg437.00€500mg954.00€1mL*10mM (DMSO)75.00€UPF 1069
CAS:UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Formula:C17H13NO3Purity:98.80% - 99.88%Color and Shape:SolidMolecular weight:279.29Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurity:99.33% - 99.86%Color and Shape:SolidMolecular weight:469.94TP-064
CAS:TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.Formula:C28H34N4O2Purity:97.85%Color and Shape:SolidMolecular weight:458.6Ref: TM-T28996
1mg35.00€2mg50.00€5mg74.00€10mg113.00€25mg231.00€50mg462.00€100mg673.00€1mL*10mM (DMSO)75.00€FLLL32
CAS:FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).Formula:C28H32O6Purity:97% - 97.90%Color and Shape:SolidMolecular weight:464.55Ref: TM-T6838
2mg43.00€5mg63.00€10mg88.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)69.00€HJ-PI01
CAS:HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.Formula:C14H11NO2Purity:98.92%Color and Shape:SolidMolecular weight:225.24Ref: TM-T9583
1mg34.00€5mg75.00€10mg110.00€25mg245.00€50mg363.00€100mg515.00€200mg700.00€1mL*10mM (DMSO)73.00€GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purity:99.75%Color and Shape:SolidMolecular weight:612.03Ref: TM-T9826
1mg93.00€5mg182.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)245.00€BRD4770
CAS:BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formula:C25H23N3O3Purity:99.53% - 99.82%Color and Shape:SolidMolecular weight:413.47G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purity:97.3%Color and Shape:SolidMolecular weight:383.39Ref: TM-T8742
1mg35.00€5mg71.00€10mg96.00€25mg172.00€50mg248.00€100mg348.00€200mg470.00€1mL*10mM (DMSO)78.00€GSK484 hydrochloride
CAS:GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.Formula:C27H32ClN5O3Purity:98.32% - 99.62%Color and Shape:SolidMolecular weight:510.03Ref: TM-TQ0067
1mg67.00€5mg140.00€10mg205.00€25mg413.00€50mg590.00€100mg840.00€1mL*10mM (DMSO)156.00€VX-11e
CAS:VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formula:C24H20Cl2FN5O2Purity:98.92% - ≥98%Color and Shape:SolidMolecular weight:500.35Decernotinib
CAS:Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formula:C18H19F3N6OPurity:99.28% - >99.99%Color and Shape:SolidMolecular weight:392.38Ref: TM-T2636
1mg34.00€2mg48.00€5mg71.00€10mg99.00€25mg197.00€50mg295.00€100mg447.00€1mL*10mM (DMSO)79.00€(E/Z)-Zotiraciclib
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formula:C23H24N4OPurity:97.75% - 99.92%Color and Shape:SolidMolecular weight:372.46Ref: TM-T21503
1mg43.00€2mg56.00€5mg93.00€10mg113.00€25mg200.00€50mg330.00€100mg480.00€1mL*10mM (DMSO)90.00€PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurity:98.74% - 99.19%Color and Shape:SolidMolecular weight:347.393-deazaneplanocin A HCl
CAS:3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.Formula:C12H15ClN4O3Purity:93.24% - 98.9%Color and Shape:SolidMolecular weight:298.73WZ4003
CAS:WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formula:C25H29ClN6O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:496.99Ref: TM-T6291
5mg48.00€10mg73.00€25mg111.00€50mg166.00€100mg241.00€200mg358.00€500mg590.00€1mL*10mM (DMSO)50.00€ABBV-744
CAS:ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55Ref: TM-T4697
1mg44.00€2mg56.00€5mg90.00€10mg142.00€25mg284.00€50mg409.00€100mg500.00€200mg718.00€1mL*10mM (DMSO)90.00€BRD9539
CAS:BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μMFormula:C24H21N3O3Purity:98% - 99.57%Color and Shape:SolidMolecular weight:399.44JNJ-42041935
CAS:JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.Formula:C12H6ClF3N4O3Purity:99.58% - ≥95%Color and Shape:SolidMolecular weight:346.65Ref: TM-T3180
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg210.00€50mg354.00€100mg567.00€500mg1,198.00€1mL*10mM (DMSO)87.00€Succinic acid sodium
CAS:Succinic acid sodium is an orally active anxiolytic.Formula:C4H6O4·xNaColor and Shape:SolidMZ 1
CAS:MZ 1 is a BRD4 protein degrader based on PROTAC technology.Formula:C49H60ClN9O8S2Purity:99.31%Color and Shape:SolidMolecular weight:1002.64dCBP-1
CAS:dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.Formula:C51H63F2N11O10Purity:98.21% - 99.12%Color and Shape:SolidMolecular weight:1028.11PHD-1-IN-1
CAS:PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).Formula:C13H8N4Purity:99.74%Color and Shape:SolidMolecular weight:220.23Ref: TM-T9627
1mg42.00€5mg92.00€10mg132.00€25mg231.00€50mg349.00€100mg522.00€200mg710.00€1mL*10mM (DMSO)90.00€Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formula:C19H36O5Purity:99.85% - 99.94%Color and Shape:SolidMolecular weight:344.49Ref: TM-T3625
2mg34.00€5mg50.00€10mg70.00€25mg118.00€50mg207.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)52.00€RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:98% - 99.91%Color and Shape:SolidMolecular weight:545.63GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43Ref: TM-T3076
1mg38.00€2mg50.00€5mg84.00€10mg137.00€25mg250.00€50mg442.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)93.00€GSK 690 Hydrochloride
CAS:GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.Formula:C24H24ClN3OPurity:98%Color and Shape:SolidMolecular weight:405.92Acetyl Pentapeptide-1 acetate
Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.Formula:C34H55N9O12Purity:99.09%Color and Shape:SolidMolecular weight:781.86Chlorogenic Acid
CAS:Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.Formula:C16H18O9Purity:98.84% - 99.67%Color and Shape:SolidMolecular weight:354.315,7,4'-Trimethoxyflavone
CAS:5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formula:C18H16O5Purity:97.53%Color and Shape:SolidMolecular weight:312.32MI-538
CAS:MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
Formula:C27H25F3N8OSPurity:99.61% - 99.8%Color and Shape:SolidMolecular weight:566.6Niraparib tosylate
CAS:Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
Formula:C19H20N4O·C7H8O3SPurity:99.34% - 99.87%Color and Shape:SolidMolecular weight:492.59JAK3-IN-6
CAS:JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormula:C19H18N4O3Purity:99.94% - 99.94%Color and Shape:SolidMolecular weight:350.37KC7F2
CAS:KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formula:C16H16Cl4N2O4S4Purity:98% - 99.11%Color and Shape:SolidMolecular weight:570.38Fucosterol
CAS:Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.Formula:C29H48OPurity:98% - 99.68%Color and Shape:White PowderMolecular weight:412.69PLX51107
CAS:PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).Formula:C26H22N4O3Purity:99.75%Color and Shape:SolidMolecular weight:438.48Ref: TM-TQ0253
1mg52.00€2mg77.00€5mg113.00€10mg178.00€25mg313.00€50mg464.00€100mg672.00€1mL*10mM (DMSO)124.00€AMI-1
CAS:AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).Formula:C21H14N2Na2O9S2Purity:98% - 99.98%Color and Shape:DrypowderMolecular weight:548.45XAV-939
CAS:XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).Formula:C14H11F3N2OSPurity:97.47% - 99.67%Color and Shape:SolidMolecular weight:312.312-hexyl-4-Pentynoic Acid
CAS:2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.Formula:C11H18O2Purity:98%Color and Shape:SolidMolecular weight:182.26AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2Aurora kinase inhibitor-2
CAS:Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).Formula:C23H20N4O3Purity:98.66%Color and Shape:SolidMolecular weight:400.43Ref: TM-T9040
1mg63.00€5mg138.00€10mg200.00€25mg360.00€50mg532.00€100mg788.00€200mg1,063.00€1mL*10mM (DMSO)150.00€Atractylenolide I
CAS:Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.30M1001
CAS:M1001 is a HIF-2α agonist.Formula:C17H17N3O2SPurity:98.83%Color and Shape:SolidMolecular weight:327.41,2-Dipalmitoyl-sn-glycerol
CAS:1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formula:C35H68O5Purity:97.84% - 99.78%Color and Shape:SolidMolecular weight:568.91
