Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2613 products of "Chromatin/Epigenetics"
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1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).Formula:C17H19NOPurity:99.08%Color and Shape:SolidMolecular weight:253.34Ref: TM-T8601
1mg58.00€5mg116.00€10mg172.00€25mg281.00€50mg396.00€100mg537.00€200mg712.00€1mL*10mM (DMSO)109.00€GSK620
CAS:GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.Formula:C18H19N3O3Purity:99.42% - 99.88%Color and Shape:SolidMolecular weight:325.36Ref: TM-T9020
2mg34.00€5mg49.00€10mg73.00€25mg136.00€50mg212.00€100mg314.00€200mg467.00€1mL*10mM (DMSO)87.00€Talazoparib
CAS:Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).Formula:C19H14F2N6OPurity:97.02% - 99.92%Color and Shape:SolidMolecular weight:380.35Ref: TM-T6253
2mg42.00€5mg62.00€10mg88.00€25mg135.00€50mg187.00€100mg311.00€200mg429.00€500mg697.00€1mL*10mM (DMSO)67.00€Solcitinib
CAS:Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.
Formula:C22H23N5O2Purity:99.61% - 99.82%Color and Shape:SolidMolecular weight:389.45Dbet57
CAS:dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.Formula:C34H31ClN8O5SPurity:99.36% - 99.52%Color and Shape:SolidMolecular weight:699.18Ref: TM-T5440
1mg47.00€5mg92.00€10mg147.00€25mg264.00€50mg409.00€100mg592.00€500mg1,224.00€1mL*10mM (DMSO)166.00€MAT2A inhibitor 4
CAS:MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancerFormula:C16H15ClFNPurity:99.17%Color and Shape:SolidMolecular weight:275.75Ref: TM-T9262
1mg40.00€5mg90.00€10mg131.00€25mg220.00€50mg314.00€100mg426.00€200mg575.00€1mL*10mM (DMSO)89.00€Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47Ref: TM-T3712
1mg55.00€2mg78.00€5mg92.00€10mg150.00€25mg244.00€50mg437.00€100mg625.00€1mL*10mM (DMSO)94.00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.623-Aminobenzamide
CAS:3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction duringFormula:C7H8N2OPurity:98.4% - 99.5%Color and Shape:White To Off-White PowderMolecular weight:136.15SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Formula:C19H17NO5SPurity:99.1% - 99.51%Color and Shape:SolidMolecular weight:371.41Ref: TM-T3986
1mg34.00€5mg74.00€10mg113.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)82.00€JNJ-64619178
CAS:JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.Formula:C22H23BrN6O2Purity:98.86% - 99.98%Color and Shape:SolidMolecular weight:483.36Ref: TM-T15624
1mg84.00€5mg167.00€10mg260.00€25mg537.00€50mg893.00€100mg1,571.00€1mL*10mM (DMSO)172.00€GeA-69
CAS:GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).Formula:C20H16N2OPurity:99.85%Color and Shape:SolidMolecular weight:300.35TTK21
CAS:TTK21 is an activator of CBP/p300 histone acetyltransferase activity.Formula:C17H15ClF3NO2Purity:98.43%Color and Shape:SolidMolecular weight:357.75Ref: TM-T8778
1mg57.00€5mg105.00€10mg158.00€25mg308.00€50mg462.00€100mg692.00€500mg1,404.00€1mL*10mM (DMSO)114.00€PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12Ref: TM-T6961
1mg39.00€5mg84.00€10mg130.00€25mg193.00€50mg261.00€100mg411.00€200mg605.00€1mL*10mM (DMSO)84.00€LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Ref: TM-T3494
2mg44.00€5mg65.00€10mg94.00€25mg173.00€50mg281.00€100mg424.00€500mg888.00€1mL*10mM (DMSO)65.00€Ref: TM-T5S2358
1mg49.00€2mg69.00€5mg105.00€10mg137.00€25mg197.00€50mg295.00€100mg447.00€1mL*10mM (DMSO)116.00€Belzutifan
CAS:"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."Formula:C17H12F3NO4SPurity:99.34% - 99.88%Color and Shape:SolidMolecular weight:383.34Ref: TM-T16679
1mg66.00€5mg144.00€10mg205.00€25mg389.00€50mg625.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)158.00€I-BET151
CAS:I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).Formula:C23H21N5O3Purity:97.34% - 99.63%Color and Shape:SolidMolecular weight:415.44Ref: TM-T2120
1mg48.00€2mg65.00€5mg96.00€10mg115.00€25mg202.00€50mg339.00€100mg507.00€500mg1,130.00€1mL*10mM (DMSO)105.00€Veliparib
CAS:Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formula:C13H16N4OPurity:98.66% - 99%Color and Shape:SolidMolecular weight:244.29Ref: TM-T2591
5mg54.00€10mg77.00€25mg120.00€50mg195.00€100mg314.00€200mg512.00€500mg807.00€1mL*10mM (DMSO)60.00€Tranylcypromine hemisulfate
CAS:Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset ofFormula:C9H11N1H2SO4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:182.23SGI-1027
CAS:SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formula:C27H23N7OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:461.52Ref: TM-T1904
5mg58.00€10mg94.00€25mg163.00€50mg296.00€100mg467.00€500mg1,035.00€1mL*10mM (DMSO)74.00€GSK467
CAS:GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formula:C17H13N5O2Purity:99.55% - 99.85%Color and Shape:SolidMolecular weight:319.32MG 149
CAS:MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46Ref: TM-T6584
1mg50.00€2mg71.00€5mg90.00€10mg167.00€25mg308.00€50mg492.00€100mg708.00€1mL*10mM (DMSO)108.00€UNC3866
CAS:UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formula:C43H66N6O8Purity:88.06% - 99.62%Color and Shape:SolidMolecular weight:795.02GW779439X
CAS:GW779439X is an inhibitor of CDK.Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45Ref: TM-T8866
1mg58.00€2mg82.00€5mg113.00€10mg178.00€25mg404.00€50mg592.00€100mg845.00€1mL*10mM (DMSO)124.00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.37G244-LM
CAS:G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.Formula:C18H22N4O3S2Purity:98.46%Color and Shape:SolidMolecular weight:406.52AMG 900
CAS:AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.58Ref: TM-T6380
1mg49.00€5mg92.00€10mg158.00€25mg286.00€50mg442.00€100mg645.00€500mg1,341.00€1mL*10mM (DMSO)100.00€3-Methoxybenzamide
CAS:3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.Formula:C8H9NO2Purity:98.52%Color and Shape:SolidMolecular weight:151.16Amifostine trihydrate
CAS:Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Fosifidancitinib
CAS:Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.Formula:C21H21FN5O7PPurity:99.54%Color and Shape:SolidMolecular weight:505.39Ref: TM-T38624
1mg93.00€2mg117.00€5mg177.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€ARV-771
CAS:ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.Formula:C49H60ClN9O7S2Purity:99.69%Color and Shape:SolidMolecular weight:986.64Ref: TM-T5435
1mg57.00€5mg113.00€10mg177.00€25mg354.00€50mg522.00€100mg732.00€200mg973.00€1mL*10mM (DMSO)192.00€Oclacitinib maleate
CAS:Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.Formula:C15H23N5O2S·C4H4O4Purity:99.17% - 99.92%Color and Shape:SolidMolecular weight:453.51Ref: TM-T6914
1mg37.00€2mg52.00€5mg74.00€10mg94.00€25mg166.00€50mg258.00€100mg432.00€1mL*10mM (DMSO)81.00€CPI-169 racemate
CAS:CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
Formula:C27H36N4O5SPurity:99.59%Color and Shape:SolidMolecular weight:528.66BET bromodomain inhibitor
CAS:BET bromodomain inhibitor is a potent BET inhibitor.Formula:C24H20ClN5O2Purity:98.22% - 99.85%Color and Shape:SolidMolecular weight:445.9Ref: TM-T2072
1mg35.00€2mg50.00€5mg75.00€10mg114.00€25mg187.00€50mg264.00€100mg416.00€1mL*10mM (DMSO)84.00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47(Z)-SMI-4a
CAS:(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM.Formula:C11H6F3NO2SPurity:97.66% - 99.93%Color and Shape:SolidMolecular weight:273.23Oclacitinib
CAS:Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000Formula:C15H23N5O2SPurity:98% - 98.45%Color and Shape:White To Off-White SolidMolecular weight:337.44lutidinic acid
CAS:lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.
Formula:C7H5NO4Purity:98.06%Color and Shape:White To Off-White Crystalline PowderMolecular weight:167.12RG108
CAS:RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).Formula:C19H14N2O4Purity:98% - 99.43%Color and Shape:SolidMolecular weight:334.33Ref: TM-T2038
5mg44.00€10mg65.00€25mg111.00€50mg195.00€100mg271.00€200mg380.00€500mg618.00€1mL*10mM (DMSO)52.00€SGC-CBP30
CAS:SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).Formula:C28H33ClN4O3Purity:99.05% - >99.99%Color and Shape:SolidMolecular weight:509.04Ref: TM-T6668
1mg50.00€2mg67.00€5mg84.00€10mg113.00€25mg200.00€50mg334.00€100mg500.00€1mL*10mM (DMSO)94.00€AZD-1480
CAS:AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in solid tumors, PPV, PMF, ET trials.Formula:C14H14ClFN8Purity:98.25% - 99.47%Color and Shape:SolidMolecular weight:348.77JAK-IN-5 hydrochloride
CAS:JAK-IN-5 hydrochloride is a JAK inhibitor [1].Formula:C27H32ClFN6OColor and Shape:SolidMolecular weight:511.03Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56ARV-825
CAS:ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formula:C46H47ClN8O9SPurity:97.15% - 98%Color and Shape:SolidMolecular weight:923.43UNC6934
CAS:UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.Formula:C24H21N5O4Purity:98.67%Color and Shape:SolidMolecular weight:443.45Ref: TM-T9584
1mg47.00€5mg92.00€10mg152.00€25mg326.00€50mg485.00€100mg670.00€200mg888.00€1mL*10mM (DMSO)101.00€Annaosanchun
CAS:Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).Formula:C19H32O3Purity:99.58%Color and Shape:SolidMolecular weight:308.46Ruboxistaurin hydrochloride
CAS:Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formula:C28H28N4O3·HClPurity:99.14% - 99.28%Color and Shape:SolidMolecular weight:505.01Ref: TM-T3689
1mg67.00€2mg87.00€5mg148.00€10mg244.00€25mg487.00€50mg702.00€100mg982.00€500mg1,963.00€1mL*10mM (DMSO)190.00€TNG-462
CAS:TNG-462 is a oral, potent and selective PRMT5 inhibitor for the treatment of MTAP-deficient and/or MTA-accumulating cancers (e.g., pancreatic & bladder).Formula:C28H36N6O2SPurity:98.7%Color and Shape:SolidMolecular weight:520.69Ref: TM-T79873
1mg147.00€5mg255.00€10mg383.00€25mg575.00€50mg863.00€100mg1,305.00€200mg1,755.00€1mL*10mM (DMSO)294.00€Osunprotafib
CAS:Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.Cost-effective and quality-assured.Formula:C17H24FN3O4SPurity:97.11% - 99.91%Color and Shape:SolidMolecular weight:385.45MDL-800
CAS:MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.Formula:C21H16BrCl2FN2O6S2Purity:99.95% - 99.96%Color and Shape:SolidMolecular weight:626.3(S)-HH2853
CAS:(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.Formula:C31H36F3N7O3Purity:97.18% - 99.74%Color and Shape:SolidMolecular weight:611.66CBHcy
CAS:CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.Formula:C9H17NO4SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:235.3Chromium(III) acetate
CAS:Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.Formula:C2H3O2CrPurity:99.9%Color and Shape:Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InMolecular weight:76.37MRK-740
CAS:MRK-740 is a PRDM9 histone methyltransferase inhibitor that inhibits H3K4 methylation.Formula:C25H32N6O3Purity:99.66%Color and Shape:SolidMolecular weight:464.56Talazoparib tosylate
CAS:PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.Formula:C26H22F2N6O4SPurity:99.79%Color and Shape:SolidMolecular weight:552.55Ref: TM-T16979
2mg39.00€5mg58.00€10mg84.00€25mg128.00€50mg178.00€100mg295.00€200mg409.00€1mL*10mM (DMSO)71.00€CX-6258 hydrochloride
CAS:CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 nM).Formula:C26H24ClN3O3·HClPurity:96.03% - 98.60%Color and Shape:SolidMolecular weight:498.4Ref: TM-T6148
1mg40.00€5mg84.00€10mg120.00€25mg222.00€50mg356.00€100mg537.00€200mg762.00€1mL*10mM (DMSO)93.00€BI-9321 trihydrochloride
CAS:BI-9321 trihydrochloride (BI9321 trihydrochloride) is an NSD3-PWWP1 antagonist that downregulates Myc messenger RNA expression.Formula:C22H24Cl3FN4Purity:99.12% - 99.34%Color and Shape:SolidMolecular weight:469.81Zavondemstat
CAS:Zavondemstat (QC8222 free base) is a KDM4 inhibitor with anticancer and antitumor activity for the study of triple-negative and breast cancers.Formula:C26H29N3O3Purity:99.43% - 99.53%Color and Shape:SolidMolecular weight:431.53CHDI-390576
CAS:CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, and HDAC 9, and can be used in cancer research.Formula:C19H13F4N3O2Purity:98.92% - 99.03%Color and Shape:SolidMolecular weight:391.32MIV-6R
CAS:MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.Formula:C27H35N3OPurity:99.81% - 99.88%Color and Shape:SolidMolecular weight:417.59RGFP966 (E-isomer)
CAS:RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.Formula:C21H19FN4OPurity:99.93%Color and Shape:SolidMolecular weight:362.4MS023 dihydrochloride
CAS:MS023 dihydrochloride (MS023 2HCl) is a human type I protein arginine methyltransferase inhibitor with antitumour activity for the study of breast cancer.Formula:C17H27Cl2N3OPurity:99.52%Color and Shape:SolidMolecular weight:360.32Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formula:C20H28ClN7O3SPurity:99.85%Color and Shape:SolidMolecular weight:482R 59-022
CAS:R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formula:C27H26FN3OSPurity:98.55%Color and Shape:SolidMolecular weight:459.58Ref: TM-T16709
1mg35.00€5mg74.00€10mg119.00€25mg269.00€50mg447.00€100mg733.00€200mg973.00€1mL*10mM (DMSO)75.00€PFI-2
CAS:PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over otherFormula:C23H25F4N3O3SPurity:99.38%Color and Shape:SolidMolecular weight:499.52MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurity:99.22%Color and Shape:SolidMolecular weight:461.94Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44Ref: TM-T2S2362
1mg89.00€5mg205.00€10mg334.00€25mg552.00€50mg782.00€100mg1,054.00€200mg1,414.00€1mL*10mM (DMSO)243.00€PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formula:C23H25F3N6O2Purity:98%Color and Shape:SolidMolecular weight:474.48SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurity:98.29%Color and Shape:SolidMolecular weight:463GSK2807 Trifluoroacetate
CAS:GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).Formula:C21H33F3N8O7Purity:99.95%Color and Shape:SolidMolecular weight:566.53NVP-BSK805
CAS:NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Formula:C27H28F2N6OPurity:98%Color and Shape:SolidMolecular weight:490.55Acedapsone
CAS:Acedapsone has antimalarial and antimicrobial action, but is mainly used as a depot leprostatic agent.Formula:C16H16N2O4SPurity:98%Color and Shape:SolidMolecular weight:332.37Tazemetostat trihydrochloride
CAS:Tazemetostat trihydrochloride, an EZH2 inhibitor, orally active, IC50: 4nM (rat), Ki: 2.5nM (human), effective in peptide and nucleosome assays.Formula:C34H47Cl3N4O4Purity:98%Color and Shape:SolidMolecular weight:682.12(R)-Dihydrolipoic acid
CAS:(R)-Dihydrolipoic acid, the biochemically significant R-enantiomer, partakes in biochemical transformations.Formula:C8H16O2S2Purity:98%Color and Shape:SolidMolecular weight:208.33TETi76
CAS:TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.Formula:C10H16O5Color and Shape:SolidMolecular weight:216.232-PADQZ
CAS:DPQ is an antiviral compound.Formula:C14H19N5O2Purity:98%Color and Shape:White PowderMolecular weight:289.33Diethyl bipy55'DC
CAS:"Diethyl bipy55'DC blocks CP4H, crucial for collagen stability via hydroxylation in cells."Formula:C16H16N2O4Purity:98%Color and Shape:SolidMolecular weight:300.31GSK 4027
CAS:GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.Formula:C17H21BrN4OColor and Shape:SolidMolecular weight:377.28Nicotinamide-d4
CAS:Nicotinamide-d4 is a deuterium-labelled compound of nicotinamide for isotope tracing. Nicotinamide, a vitamin B3 derivative, inhibits SIRT1 and SIRT2.Formula:C6H2D4N2OPurity:99.746%Color and Shape:SolidMolecular weight:126.15193 D7
CAS:193 D7 is an inhibitor of histone demethylase JMJD1C (IC50= 0.59 μM in in vitro demethylation assay). In vivo, 193 D7 suppresses tumors by targeting intratumoral Treg cells in mouse tumor models.Formula:C16H15NO4SColor and Shape:SolidMolecular weight:317.36BRD 4354 ditrifluoroacetate
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).Formula:C25H25ClF6N4O5Purity:98%Color and Shape:SolidMolecular weight:610.93KR-39038
CAS:KR-39038 is an oral GRK5 inhibitor for heart failure research; blocks HDAC5 pathway, IC50: 0.02 μM, fights cardiac hypertrophy.Formula:C24H32ClFN6OColor and Shape:SolidMolecular weight:475.00CrBKA
CAS:CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity [1] .Formula:C28H31N3O6Color and Shape:SolidMolecular weight:505.56BChE/HDAC6-IN-2
CAS:BChE/HDAC6-IN-2 is an inhibitor of BChE and HDAC6 with neuroprotective and ROS scavenging activity and a metal ion co-agonist and inhibits tau phosphorylation.Formula:C27H30N4O4Purity:98.47%Color and Shape:SoildMolecular weight:474.55AdipoR agonist 1
CAS:AdipoR agonist 1 (Compound 112254), acting as an agonist for the adiponectin receptor (AdipoR), stimulates transcriptional regulators including peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). It is employed in the field of preventive doping research.Formula:C26H35N3O3Color and Shape:SolidMolecular weight:437.57BG14
CAS:BG14: High-res optical epigenetic control; photo-inhibits human histone deacetylases with visible light.Formula:C21H21N5OColor and Shape:SolidMolecular weight:359.433I-BET787
CAS:I-BET787, an orally active pan-BET bromodomain inhibitor, has demonstrated efficacy in murine inflammation models.Formula:C16H20ClN3O2Color and Shape:SolidMolecular weight:321.80HDAC2-IN-2
CAS:HDAC2-IN-2 (compound 124) acts as an HDAC2 inhibitor, exhibiting a Kd value ranging from 0.1-1 μM.Formula:C18H15N3O3SColor and Shape:SolidMolecular weight:353.40BG47
CAS:BG47: a COMET probe for precise optical epigenetic control, inhibits histone deacetylases with light.Formula:C25H22N4O2SColor and Shape:SolidMolecular weight:442.54GSK-J1 lithium salt
CAS:GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B.Formula:C22H22LiN5O2Purity:98%Color and Shape:SolidMolecular weight:395.38Guanosine-5'-triphosphate disodium salt
CAS:5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.Formula:C10H14N5Na2O14P3Purity:95.69% - 99.96%Color and Shape:Odorless White SolidMolecular weight:567.14BG48
CAS:BG48, a COMET probe, enables precise optical epigenetic control and photochromically blocks human histone deacetylases with visible light.Formula:C25H23N5OSColor and Shape:SolidMolecular weight:441.55KAT6-IN-1
CAS:KAT6-IN-1 (compound E) is a selective, orally available inhibitor of histone acetyltransferases KAT6A and KAT6B, exhibiting antitumour activity for cancer.Formula:C19H18N4O5SPurity:99.86%Color and Shape:SolidMolecular weight:414.43Asteltoxin
CAS:Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Formula:C23H30O7Color and Shape:SolidMolecular weight:418.486PKCTheta-IN-2
CAS:PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor (IC50 = 0.25 nM) that suppresses IL-2 production in mice (IC50 = 682 nM).Formula:C24H23N5O2Purity:99.38%Color and Shape:SolidMolecular weight:413.47HDAC6-IN-27
CAS:HDAC6-IN-27 (compound 8C), an HDAC inhibitor, exhibits IC 50 values of 15.9 nM, 136.5 nM, and 6180.2 nM against HDAC6, HDAC8, and HDAC1, respectively. It also demonstrates potent antiparasitic effects [1].Formula:C15H15N3O4Color and Shape:SolidMolecular weight:301.3(3S,4S)-Tofacitinib
CAS:(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Formula:C16H20N6OPurity:98%Color and Shape:SolidMolecular weight:312.37E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purity:99.32% - 99.37%Color and Shape:SolidMolecular weight:504.61Ref: TM-T16526
1mg58.00€5mg160.00€10mg268.00€25mg530.00€50mg827.00€100mg1,314.00€200mg1,773.00€1mL*10mM (DMSO)170.00€
