Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2611 products of "Chromatin/Epigenetics"
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Iniparib
CAS:Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).Formula:C7H5IN2O3Purity:98.93%Color and Shape:SolidMolecular weight:292.03Ref: TM-T6224
5mg52.00€10mg73.00€25mg119.00€50mg216.00€100mg340.00€200mg540.00€500mg863.00€1mL*10mM (DMSO)52.00€GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43Ref: TM-T3076
1mg38.00€2mg50.00€5mg84.00€10mg137.00€25mg250.00€50mg442.00€100mg623.00€500mg1,305.00€1mL*10mM (DMSO)93.00€NVP-TNKS656
CAS:NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58Ref: TM-T3261
1mg43.00€2mg54.00€5mg84.00€10mg122.00€25mg248.00€50mg421.00€100mg617.00€1mL*10mM (DMSO)93.00€RBN012759
CAS:RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.Formula:C19H23FN2O3SPurity:98.87% - 99.96%Color and Shape:SolidMolecular weight:378.46Ref: TM-T22414
1mg104.00€2mgTo inquire5mg250.00€10mg373.00€25mg645.00€50mg938.00€100mg1,311.00€200mg1,768.00€1mL*10mM (DMSO)274.00€MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86Ref: TM-T6315
1mg50.00€2mg67.00€5mg84.00€10mg120.00€25mg220.00€50mg356.00€100mg537.00€1mL*10mM (DMSO)88.00€1,2-Dipalmitoyl-sn-glycerol
CAS:1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formula:C35H68O5Purity:97.84% - 99.78%Color and Shape:SolidMolecular weight:568.91Ruboxistaurin mesylate
CAS:Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.Formula:C29H32N4O6SPurity:98%Color and Shape:SolidMolecular weight:564.65AZ505
CAS:AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formula:C29H38Cl2N4O4Purity:98.18%Color and Shape:SolidMolecular weight:577.54Ref: TM-TQ0100
1mg60.00€5mg130.00€10mg178.00€25mg295.00€50mg462.00€100mg623.00€1mL*10mM (DMSO)165.00€MR837
CAS:MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formula:C16H14N2OSPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:282.36Ref: TM-T8879
2mg38.00€5mg55.00€10mg92.00€25mg138.00€50mg243.00€100mg355.00€200mg502.00€1mL*10mM (DMSO)66.00€MK-8617
CAS:MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).Formula:C24H21N5O4Purity:99.38% - >99.99%Color and Shape:SolidMolecular weight:443.45Bromosporine
CAS:Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.44Ref: TM-T6255
1mg44.00€2mg57.00€5mg93.00€10mg133.00€25mg260.00€50mg416.00€100mg665.00€200mg888.00€1mL*10mM (DMSO)92.00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47Ref: TM-T8685
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)177.00€8-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)Formula:C8H5ClN2OPurity:98.79%Color and Shape:SolidMolecular weight:180.59(R)-(-)-JQ1 Enantiomer
CAS:(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)
Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99ICG001
CAS:ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.Formula:C33H32N4O4Purity:99.06% - 99.95%Color and Shape:SolidMolecular weight:548.63Ref: TM-T2237
1mg34.00€5mg66.00€10mg101.00€25mg197.00€50mg341.00€100mg530.00€500mg1,134.00€1mL*10mM (DMSO)81.00€Rucaparib hydrochloride
CAS:Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.Formula:C19H19ClFN3OColor and Shape:SolidMolecular weight:359.83GSK1379725A
CAS:GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
Formula:C23H23FN6O3Purity:99.51%Color and Shape:SolidMolecular weight:450.47DMOG
CAS:DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14Bobcat339
CAS:Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formula:C16H12ClN3OPurity:97.79% - 98.76%Color and Shape:SolidMolecular weight:297.74Rucaparib acetate
CAS:Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.Formula:C21H22FN3O3Color and Shape:SolidMolecular weight:383.423JQEZ5
CAS:JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formula:C30H38N8O2Purity:98.14% - ≥98%Color and Shape:SolidMolecular weight:542.68Protein kinase inhibitor 6
CAS:Protein kinase inhibitor 6 is a protein kinase inhibitor.Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29Ref: TM-T9779
2mg34.00€5mg52.00€10mg86.00€25mg163.00€50mg222.00€100mg324.00€200mg440.00€1mL*10mM (DMSO)52.00€MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formula:C103H156N28O24S2Purity:100%Color and Shape:SolidMolecular weight:2234.64EB-47 dihydrochloride
CAS:EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Formula:C24H29Cl2N9O6Color and Shape:SolidMolecular weight:610.45PIN1 inhibitor API-1
CAS:API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formula:C15H13F3N6O2Purity:98.48%Color and Shape:SolidMolecular weight:366.3Ref: TM-T16538
1mg57.00€5mg120.00€10mg222.00€25mg326.00€50mg485.00€100mg612.00€200mg850.00€500mg1,243.00€1mL*10mM (DMSO)133.00€Amodiaquine
CAS:Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formula:C20H22ClN3OPurity:99.78% - 99.99%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86Ref: TM-T8381
1mg49.00€2mg66.00€5mg90.00€10mg170.00€25mg281.00€50mg394.00€100mg550.00€1mL*10mM (DMSO)105.00€XMD8-92
CAS:XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55Ruboxistaurin
CAS:Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.Formula:C28H28N4O3Color and Shape:SolidMolecular weight:468.55YKL-06-061
CAS:YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formula:C30H37N7O2Purity:99.52% - 99.79%Color and Shape:SolidMolecular weight:527.66MS31 trihydrochloride
MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.Formula:C20H30Cl3N3O2Color and Shape:SolidMolecular weight:450.83SC-43
CAS:SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.85-Ph-IAA
CAS:5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.
Formula:C16H13NO2Purity:99.37% - 99.973%Color and Shape:SolidMolecular weight:251.28Ethyl 3,4-dihydroxybenzoate
CAS:Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17Birabresib
CAS:Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4Formula:C25H22ClN5O2SPurity:98.3% - 99.36%Color and Shape:SolidMolecular weight:491.99Ref: TM-T6032
2mg46.00€5mg70.00€10mg90.00€25mg142.00€50mg222.00€100mg375.00€200mg560.00€500mg893.00€1mL*10mM (DMSO)74.00€(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurity:97.57% - 99.97%Color and Shape:SolidMolecular weight:456.99Ref: TM-T2110
1mg34.00€2mg42.00€5mg57.00€10mg74.00€25mg90.00€50mg137.00€100mg178.00€200mg268.00€500mg485.00€1mL*10mM (DMSO)63.00€AZD-2461
CAS:AZD2461 is a novel PARP inhibitor.Formula:C22H22FN3O3Purity:98% - 99.87%Color and Shape:SolidMolecular weight:395.43Menin-MLL inhibitor 20
CAS:Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formula:C33H40N8O4Purity:97.77%Color and Shape:SolidMolecular weight:612.72Ref: TM-T9399
1mg38.00€5mg86.00€10mg128.00€25mg250.00€50mg369.00€100mg527.00€200mg712.00€1mL*10mM (DMSO)95.00€Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41Isoxazole
CAS:Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formula:C3H3NOPurity:98% - 99.34%Color and Shape:Colorless LiquidMolecular weight:69.06Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14UMB298
CAS:UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.Formula:C27H31ClN4O2Purity:99.76%Color and Shape:SolidMolecular weight:479.01Ref: TM-T9194
1mg46.00€5mg94.00€10mg149.00€25mg250.00€50mg351.00€100mg480.00€200mg622.00€1mL*10mM (DMSO)99.00€3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS:3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .Formula:C9H10N2OPurity:99.3% - 99.64%Color and Shape:SolidMolecular weight:162.19Ref: TM-T50006
2mg37.00€5mg52.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€500mg642.00€1mL*10mM (DMSO)56.00€Alobresib
CAS:Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.Formula:C26H23N5O2Purity:97.63%Color and Shape:SolidMolecular weight:437.49Ref: TM-T8495
1mg70.00€2mg87.00€5mg137.00€10mg260.00€25mg507.00€50mg713.00€100mg982.00€1mL*10mM (DMSO)150.00€PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ref: TM-T8764
1mg107.00€2mg152.00€5mg219.00€10mg349.00€25mg583.00€50mg833.00€100mg1,134.00€500mg2,268.00€1mL*10mM (DMSO)226.00€Tubacin
CAS:Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.Formula:C41H43N3O7SPurity:97.62% - 98.75%Color and Shape:SolidMolecular weight:721.86MT-DADMe-ImmA
CAS:MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).Formula:C13H19N5OSPurity:99.56%Color and Shape:SolidMolecular weight:293.39Ref: TM-TQ0008
1mg70.00€5mg135.00€10mg225.00€25mg399.00€50mg560.00€100mg787.00€200mg1,035.00€1mL*10mM (DMSO)169.00€Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formula:C21H27N7OPurity:98% - 99.45%Color and Shape:SolidMolecular weight:393.49Ref: TM-T1825
1mg35.00€2mg50.00€5mg66.00€10mg84.00€25mg156.00€50mg212.00€100mg371.00€1mL*10mM (DMSO)66.00€J-147
CAS:J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.Formula:C18H17F3N2O2Purity:99.61% - >99.99%Color and Shape:SolidMolecular weight:350.33N-Oxalylglycine
CAS:N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.Formula:C4H5NO5Purity:99.23%Color and Shape:Colourless SolidMolecular weight:147.09TFMB-(R)-2-HG
CAS:TFMB-(R)-2-HG, a carcinogen in AML, hinders SCF ER-Hoxb8 differentiation after estrogen loss.Formula:C13H11F3O4Purity:97.15%Color and Shape:SolidMolecular weight:288.22Ref: TM-T17065
1mg73.00€5mg158.00€10mg236.00€25mg429.00€50mg640.00€100mg888.00€1mL*10mM (DMSO)133.00€
