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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 958 products of "DNA Damage/DNA Repair"

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  • Bendamustine
    Targetmol
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    Bendamustine

    CAS:
    <p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>
    Formula:C16H21Cl2N3O2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:358.26

    Ref: TM-T8380

  • Genz-644282
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    Genz-644282

    CAS:
    <p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>
    Formula:C22H21N3O5
    Purity:97.49%
    Color and Shape:Solid
    Molecular weight:407.42

    Ref: TM-T7187

  • Pentamidine
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    Pentamidine

    CAS:
    <p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>
    Formula:C19H24N4O2
    Purity:98.64% - 99.67%
    Color and Shape:Crystallizes As Colorless Plates From Water Solid
    Molecular weight:340.42

    Ref: TM-T23133

  • TIQ-A
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    TIQ-A

    CAS:
    <p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>
    Formula:C11H7NOS
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:201.24

    Ref: TM-T50098

  • AZD-2461
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    AZD-2461

    CAS:
    <p>AZD2461 is a novel PARP inhibitor.</p>
    Formula:C22H22FN3O3
    Purity:98% - 99.87%
    Color and Shape:Solid
    Molecular weight:395.43

    Ref: TM-T2484

  • Dxd
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    Dxd

    CAS:
    <p>Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs. High-Quality, Low-Cost!</p>
    Formula:C26H24FN3O6
    Purity:98.21% - ≥98%
    Color and Shape:Solid
    Molecular weight:493.48

    Ref: TM-T11249L

  • Pyridostatin
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    Pyridostatin

    CAS:
    <p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>
    Formula:C31H32N8O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.64

    Ref: TM-T1899

  • TMPyP4 tosylate
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    TMPyP4 tosylate

    CAS:
    <p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>
    Formula:C72H66N8O12S4
    Purity:98.61% - 99.85%
    Color and Shape:Solid
    Molecular weight:1363.6

    Ref: TM-T13174

  • UPF 1069
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    UPF 1069

    CAS:
    <p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>
    Formula:C17H13NO3
    Purity:98.80% - 99.88%
    Color and Shape:Solid
    Molecular weight:279.29

    Ref: TM-T6181

  • KU-57788
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    KU-57788

    CAS:
    <p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>
    Formula:C25H19NO3S
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:413.49

    Ref: TM-T6276

  • EDO-S101
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    EDO-S101

    CAS:
    <p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>
    Formula:C19H28Cl2N4O2
    Purity:98.02% - 99.44%
    Color and Shape:Solid
    Molecular weight:415.36

    Ref: TM-T3516

  • Thiomyristoyl
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    Thiomyristoyl

    CAS:
    <p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>
    Formula:C34H51N3O3S
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:581.85

    Ref: TM-T3447

  • Trovafloxacin
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    Trovafloxacin

    CAS:
    <p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>
    Formula:C20H15F3N4O3
    Purity:99.21% - 99.27%
    Color and Shape:Solid
    Molecular weight:416.35

    Ref: TM-T13231

  • SCR130
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    SCR130

    CAS:
    <p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>
    Formula:C19H13Cl2N3O2S
    Purity:98.9%
    Color and Shape:Solid
    Molecular weight:418.3

    Ref: TM-T9150

  • CC-115 hydrochloride
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    CC-115 hydrochloride

    CAS:
    <p>CC-115 hydrochloride: potent DNA-PK/mTOR inhibitor; IC50s: 13 nM and 21 nM; blocks mTORC1/C2 pathways.</p>
    Formula:C16H17ClN8O
    Color and Shape:Solid
    Molecular weight:372.82

    Ref: TM-T61505

  • PARP1-IN-5 dihydrochloride 
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    PARP1-IN-5 dihydrochloride 

    CAS:
    <p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>
    Formula:C25H26Cl2N2O5S
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:537.46

    Ref: TM-T9610

  • Remodelin hydrobromide
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    Remodelin hydrobromide

    CAS:
    <p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>
    Formula:C15H15BrN4S
    Purity:97.22% - 99.84%
    Color and Shape:Solid
    Molecular weight:363.275

    Ref: TM-T6133

  • Furegrelate
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    Furegrelate

    CAS:
    <p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>
    Formula:C15H11NO3
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:253.25

    Ref: TM-T11339L

  • AZ32
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    AZ32

    CAS:
    <p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of &lt;6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>
    Formula:C20H16N4O
    Purity:98.68% - 99.68%
    Color and Shape:Solid
    Molecular weight:328.37

    Ref: TM-T4443

  • AZ9482
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    AZ9482

    CAS:
    <p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 &lt; 18 nM.</p>
    Formula:C26H22N6O2
    Purity:99.18% - 99.86%
    Color and Shape:Solid
    Molecular weight:450.49

    Ref: TM-T22264