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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 958 products of "DNA Damage/DNA Repair"

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  • OUL35

    CAS:
    <p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>
    Formula:C14H12N2O3
    Purity:99.2%
    Color and Shape:Solid
    Molecular weight:256.26
  • RU.521

    CAS:
    <p>RU.521 (RU3205217) is a selective cyclic GMP-AMP synthetase (cGAS) inhibitor (mouse: IC50=0.11 μM), (human: IC50=2.94 μM). High-Quality, Low-Cost!</p>
    Formula:C19H12Cl2N4O3
    Purity:98% - 99.78%
    Color and Shape:Solid
    Molecular weight:415.23
  • Niraparib hydrochloride

    CAS:
    <p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>
    Formula:C19H21ClN4O
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:356.85
  • Cycloastragenol

    CAS:
    <p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>
    Formula:C30H50O5
    Purity:99.85% - 99.92%
    Color and Shape:Solid
    Molecular weight:490.71
  • Rucaparib Phosphate

    CAS:
    <p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>
    Formula:C19H18FN3O·H3PO4
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:421.36
  • VAL-083

    CAS:
    <p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>
    Formula:C6H10O4
    Purity:97.94%
    Color and Shape:Solid
    Molecular weight:146.14
  • GNE-3511

    CAS:
    <p>GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.</p>
    Formula:C23H26F2N6O
    Purity:98.3% - 99.51%
    Color and Shape:Solid
    Molecular weight:440.49
  • Effusanin A

    CAS:
    <p>Effusanin A: antibacterial, damages DNA, inhibits DU145 cells at 3.16 μM and LoVo cells at 3.02 μM.</p>
    Formula:C20H28O5
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:348.43
  • OAC1

    CAS:
    <p>OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.</p>
    Formula:C14H11N3O
    Purity:99.49% - 99.65%
    Color and Shape:Solid
    Molecular weight:237.26
  • SirReal2

    CAS:
    <p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>
    Formula:C22H20N4OS2
    Purity:98.96% - 99.75%
    Color and Shape:Solid
    Molecular weight:420.55
  • Rucaparib monocamsylate

    CAS:
    <p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>
    Formula:C29H34FN3O5S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:555.66
  • JW 55

    CAS:
    <p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>
    Formula:C25H26N2O5
    Purity:99.31% - 99.76%
    Color and Shape:Solid
    Molecular weight:434.48
  • XAV-939

    CAS:
    <p>XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).</p>
    Formula:C14H11F3N2OS
    Purity:97.47% - 99.67%
    Color and Shape:Solid
    Molecular weight:312.31
  • BCH001

    CAS:
    <p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>
    Formula:C20H15F3N2O5
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:420.34
  • DOPE

    CAS:
    <p>DOPE, a neutral lipid, boosts cationic liposome efficiency in non-viral gene delivery.</p>
    Formula:C41H78NO8P
    Purity:97.23% - ≥98%
    Color and Shape:Lyophilized Powder
    Molecular weight:744.03
  • PIK-93

    CAS:
    PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
    Formula:C14H16ClN3O4S2
    Purity:97.72%
    Color and Shape:Solid
    Molecular weight:389.88
  • Bisantrene

    CAS:
    <p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>
    Formula:C22H22N8
    Purity:96.07% - 98.57%
    Color and Shape:Solid
    Molecular weight:398.46
  • Rabdosiin

    CAS:
    <p>Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.</p>
    Formula:C36H30O16
    Purity:98.64% - 99.49%
    Color and Shape:Solid
    Molecular weight:718.61
  • MC1568

    CAS:
    <p>MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B.</p>
    Formula:C17H15FN2O3
    Purity:89.82% - ≥95%
    Color and Shape:Solid
    Molecular weight:314.31
  • Veliparib dihydrochloride

    CAS:
    <p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>
    Formula:C13H18Cl2N4O
    Purity:98% - 99.81%
    Color and Shape:Solid
    Molecular weight:317.21