DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(422 products)
- DNA gyrase(11 products)
- DNA-PK(50 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 963 products of "DNA Damage/DNA Repair"
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3,4-Dicaffeoylquinic acid
CAS:<p>3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.</p>Formula:C25H24O12Purity:96.33% - 98.82%Color and Shape:SolidMolecular weight:516.45Seclidemstat
CAS:<p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>Formula:C20H23ClN4O4SPurity:98.28% - 99.76%Color and Shape:SolidMolecular weight:450.94Veliparib dihydrochloride
CAS:<p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>Formula:C13H18Cl2N4OPurity:98% - 99.81%Color and Shape:SolidMolecular weight:317.21Prexasertib dihydrochloride
CAS:<p>Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.</p>Formula:C18H21Cl2N7O2Purity:98.46% - 99.82%Color and Shape:SolidMolecular weight:438.316-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:98.75% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19SIS17
CAS:<p>SIS17: Potent, selective HDAC11 inhibitor (IC50: 0.83 μM), blocks serine hydroxymethyl transferase 2 demyristoylation, spares other HDACs.</p>Formula:C21H38N2OSPurity:98.22%Color and Shape:SolidMolecular weight:366.6CC-115
CAS:CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).Formula:C16H16N8OPurity:86.79% - 99.01%Color and Shape:SolidMolecular weight:336.35SRT 1460
CAS:<p>SRT 1460 is a SIRT1 activator.</p>Formula:C26H29N5O4SPurity:98.25%Color and Shape:SolidMolecular weight:507.6Venadaparib
CAS:<p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>Formula:C23H23FN4O2Purity:99.86%Color and Shape:SolidMolecular weight:406.45Ochromycinone
CAS:<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Formula:C19H14O4Purity:99.21%Color and Shape:SolidMolecular weight:306.315-Methyl-2'-deoxycytidine
CAS:<p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>Formula:C10H15N3O4Purity:99.18% - 99.69%Color and Shape:SolidMolecular weight:241.245-Fluoro-2'-deoxycytidine
CAS:<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Formula:C9H12FN3O4Purity:97.91%Color and Shape:Fine White PowderMolecular weight:245.21Bimolane
CAS:Bimolane is a topoisomerase II inhibitor.Formula:C20H32N6O6Purity:99.13% - 99.29%Color and Shape:SolidMolecular weight:452.5Amsacrine hydrochloride
CAS:<p>Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.</p>Formula:C21H20ClN3O3SPurity:99.05% - 99.92%Color and Shape:SolidMolecular weight:429.92Levofloxacin
CAS:Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.Formula:C18H20FN3O4Purity:98.14% - 99.80%Color and Shape:Off-White To Yellow CrystalsMolecular weight:361.37ACY-738
CAS:ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.Formula:C14H14N4O2Purity:98.85% - 99.89%Color and Shape:SolidMolecular weight:270.29YU238259
CAS:YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.Formula:C22H22ClN3O4SPurity:99.28% - 99.56%Color and Shape:SolidMolecular weight:459.95GeA-69
CAS:<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Formula:C20H16N2OPurity:99.85%Color and Shape:SolidMolecular weight:300.35Talazoparib
CAS:<p>Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).</p>Formula:C19H14F2N6OPurity:97.02% - 99.92%Color and Shape:SolidMolecular weight:380.35Tunicamycin
CAS:<p>Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT).</p>Formula:C39H64N4O16Purity:98.77%Color and Shape:White Crystalline SolidMolecular weight:844.94 (n=10)
