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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 1006 products of "DNA Damage/DNA Repair"

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  • Hypericin

    CAS:
    <p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>
    Formula:C30H16O8
    Purity:99.05% - ≥98%
    Color and Shape:Red-Coloured Anthraquinone-Derivative
    Molecular weight:504.44
  • PIK-75

    CAS:
    <p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>
    Formula:C16H14BrN5O4S
    Purity:98.52% - >99.99%
    Color and Shape:Solid
    Molecular weight:452.28
  • RG108

    CAS:
    RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).
    Formula:C19H14N2O4
    Purity:98% - 99.43%
    Color and Shape:Solid
    Molecular weight:334.33
  • ETP-46464

    CAS:
    ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
    Formula:C30H22N4O2
    Purity:97.76%
    Color and Shape:Solid
    Molecular weight:470.52
  • Brincidofovir

    CAS:
    Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir.
    Formula:C27H52N3O7P
    Purity:98% - 99.62%
    Color and Shape:Solid
    Molecular weight:561.69
  • Neobavaisoflavone

    CAS:
    Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.
    Formula:C20H18O4
    Purity:99.31% - 99.92%
    Color and Shape:Solid
    Molecular weight:322.35
  • IndiMitecan

    CAS:
    <p>IndiMitecan (LMP776) is an inhibitor of topoisomerase I (Top1) with anticancer activities [1].</p>
    Formula:C25H21N3O6
    Purity:98.53%
    Color and Shape:Soild
    Molecular weight:459.45
  • MDL-800

    CAS:
    <p>MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.</p>
    Formula:C21H16BrCl2FN2O6S2
    Purity:99.95% - 99.96%
    Color and Shape:Solid
    Molecular weight:626.3
  • CBHcy

    CAS:
    <p>CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.</p>
    Formula:C9H17NO4S
    Purity:>99.99% - >99.99%
    Color and Shape:Solid
    Molecular weight:235.3
  • RGFP966 (E-isomer)

    CAS:
    RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.
    Formula:C21H19FN4O
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:362.4
  • CHDI-390576

    CAS:
    CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, and HDAC 9, and can be used in cancer research.
    Formula:C19H13F4N3O2
    Purity:98.92% - 99.03%
    Color and Shape:Solid
    Molecular weight:391.32
  • Exatecan

    CAS:
    Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).Exatecan has antitumor activity and may be used in
    Formula:C24H22FN3O4
    Purity:99.69% - 99.91%
    Color and Shape:Solid
    Molecular weight:435.45
  • Semustine

    CAS:
    <p>Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for</p>
    Formula:C10H18ClN3O2
    Purity:99.70%
    Color and Shape:Light Yellow Powder
    Molecular weight:247.72
  • TETi76

    CAS:
    TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.
    Formula:C10H16O5
    Color and Shape:Solid
    Molecular weight:216.23
  • Mirin

    CAS:
    Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor and also inhibits Mre11-associated exonuclease activity.Mirin induces cell cycle arrest in G1 phase.
    Formula:C10H8N2O2S
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:220.25
  • Cyclophosphamide-d4

    CAS:
    <p>Cyclophosphamide-d4 is a deuterated compound of Cyclophosphamide. Cyclophosphamide has a CAS number of 50-18-0. Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.</p>
    Formula:C7H11D4Cl2N2O2P
    Color and Shape:Solid
    Molecular weight:265.11
  • Palmitoyllactic acid

    CAS:
    Palmitoyllactic acid is a long-chain fatty acid.
    Formula:C19H36O4
    Color and Shape:Solid
    Molecular weight:328.49
  • PNU-159682

    CAS:
    PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin.
    Formula:C32H35NO13
    Purity:98.24%
    Color and Shape:Solid
    Molecular weight:641.62
  • BRD 4354 ditrifluoroacetate


    BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
    Formula:C25H25ClF6N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:610.93
  • ART0380

    CAS:
    <p>ART0380 is a potent, antitumor, selective, orally available, ATP-competitive ATR kinase inhibitor for the study of ataxia telangiectasia mutated (ATM) cancer.</p>
    Formula:C18H24N6O2S
    Purity:99.06% - >99.99%
    Color and Shape:Solid
    Molecular weight:388.49