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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 959 products of "DNA Damage/DNA Repair"

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  • ITF3756
    Targetmol
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    ITF3756

    CAS:
    <p>ITF3756 is a selective HDAC6 inhibitor.</p>
    Formula:C13H11N5O2S
    Purity:97.74%
    Color and Shape:Solid
    Molecular weight:301.32

    Ref: TM-T69735

  • ATR-IN-10
    Targetmol
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    ATR-IN-10

    CAS:
    <p>ATR-IN-10 is a potent and highly selective inhibitor of ATR kinase (IC50: 2.978 μM).</p>
    Formula:C27H24N4O
    Color and Shape:Solid
    Molecular weight:420.51

    Ref: TM-T62233

  • Hepsulfam
    Targetmol
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    Hepsulfam

    CAS:
    <p>Hepsulfam is an anticancer agent. It also displays excellent antileukemic activity (a median IC50: 0.91 μg/mL in a panel of different tumors).</p>
    Formula:C7H18N2O6S2
    Color and Shape:Solid
    Molecular weight:290.36

    Ref: TM-T15472

  • CM-579
    Targetmol
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    CM-579

    CAS:
    <p>CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.</p>
    Formula:C29H40N4O3
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:492.65

    Ref: TM-T10840L

  • C-333H
    Targetmol
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    C-333H

    CAS:
    <p>C-333H is a new PPARalpha/gamma dual agonist.</p>
    Formula:C28H26N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:486.52

    Ref: TM-T25198

  • F-14512
    Targetmol
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    F-14512

    CAS:
    <p>F-14512, a DNA topoisomerase II inhibitor, is used potentially for the treatment of acute myeloid leukemia.</p>
    Formula:C33H47N5O8
    Color and Shape:Solid
    Molecular weight:641.76

    Ref: TM-T27299

  • MHY908
    Targetmol
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    MHY908

    CAS:
    <p>MHY908, a novel inhibitor of melanogenesis, potently inhibits mushroom tyrosinase activity in a dose-dependent manner.</p>
    Formula:C17H14ClNO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:347.82

    Ref: TM-T28035

  • S26948
    Targetmol
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    S26948

    CAS:
    <p>S26948 is a PPARγ agonist.</p>
    Formula:C28H25NO7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:519.57

    Ref: TM-T23304

  • Topoisomerase IIα-IN-1
    Targetmol
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    Topoisomerase IIα-IN-1

    CAS:
    <p>Topoisomerase IIα-IN-1 (compound 2) is a DNA-binding ligands and a potent inhibitor of TopoIIα, a topoisomerase.</p>
    Formula:C22H20N4O5
    Color and Shape:Solid
    Molecular weight:420.42

    Ref: TM-T62223

  • KRP-297
    Targetmol
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    KRP-297

    CAS:
    <p>KRP297 is a PPAR agonist potentially for the treatment of type 2 diabetes and dyslipidemia.</p>
    Formula:C20H17F3N2O4S
    Color and Shape:Solid
    Molecular weight:438.42

    Ref: TM-T27749

  • MPT0G211
    Targetmol
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    MPT0G211

    CAS:
    <p>MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for Alzheimer's.</p>
    Formula:C17H15N3O2
    Purity:98% - 99.88%
    Color and Shape:Solid
    Molecular weight:293.32

    Ref: TM-T60616

  • ST247
    Targetmol
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    ST247

    CAS:
    <p>ST247: Potent PPARβ/δ inverse agonist, blocks CCL2 expression and agonist-driven PPARβ/δ transcription, promotes co-repressor interaction.</p>
    Formula:C19H26N2O5S2
    Color and Shape:Solid
    Molecular weight:426.55

    Ref: TM-T62321

  • SW155246
    Targetmol
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    SW155246

    CAS:
    <p>SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM).</p>
    Formula:C16H11ClN2O5S
    Purity:98.99%
    Color and Shape:Solid
    Molecular weight:378.79

    Ref: TM-T8967

  • DC_501
    Targetmol
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    DC_501

    CAS:
    <p>DC_501 is a selective non-nucleoside DNA methyltransferase 1 inhibitor.</p>
    Formula:C25H23Cl2N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.38

    Ref: TM-T23968

  • XR 5944
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    XR 5944

    CAS:
    <p>XR 5944 is an effective DNA binder that stabilizes topoisomerase-dependent cleavage and has shown superior efficacy in a variety of mouse and human tumor models</p>
    Formula:C34H34N8O2
    Purity:98.29% - 98.66%
    Color and Shape:Solid
    Molecular weight:586.69

    Ref: TM-T35187

  • Huanglongmycin N
    Targetmol
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    Huanglongmycin N

    CAS:
    <p>Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.</p>
    Formula:C19H16O5
    Color and Shape:Solid
    Molecular weight:324.33

    Ref: TM-T72727

  • DNA-PK-IN-1
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    DNA-PK-IN-1

    CAS:
    <p>DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.</p>
    Formula:C23H26N8O2
    Color and Shape:Solid
    Molecular weight:446.5

    Ref: TM-T62648

  • Eicosatetraynoic acid
    Targetmol
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    Eicosatetraynoic acid

    CAS:
    <p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>
    Formula:C20H24O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.4

    Ref: TM-T11169

  • DNA-PK-IN-3
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    DNA-PK-IN-3

    CAS:
    <p>DNA-PK-IN-3 is a potent DNA-PK inhibitor, enhancing radio/chemotherapy and reducing tumors with limited side effects.</p>
    Formula:C19H19N9O
    Color and Shape:Solid
    Molecular weight:389.41

    Ref: TM-T61751

  • TFMB-(S)-2-HG
    Targetmol
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    TFMB-(S)-2-HG

    CAS:
    <p>TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.</p>
    Formula:C13H11F3O4
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:288.22

    Ref: TM-T24871

  • CP 775146
    Targetmol
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    CP 775146

    CAS:
    <p>PPARα agonist</p>
    Formula:C26H33NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:423.54

    Ref: TM-T22686

  • (S)-Gyramide A
    Targetmol
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    (S)-Gyramide A

    CAS:
    <p>(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division.</p>
    Formula:C21H27FN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.51

    Ref: TM-T23578

  • Topoisomerase II inhibitor 4
    Targetmol
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    Topoisomerase II inhibitor 4

    CAS:
    <p>Compound E17, a topoisomerase II inhibitor, halts cell cycle at G2/M, possesses anticancer properties and cytotoxic effects.</p>
    Formula:C25H25N5O4
    Color and Shape:Solid
    Molecular weight:459.5

    Ref: TM-T62887

  • 5-Aza-4'-thio-2'-deoxycytidine
    Targetmol
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    5-Aza-4'-thio-2'-deoxycytidine

    CAS:
    <p>5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].</p>
    Formula:C8H12N4O3S
    Color and Shape:Solid
    Molecular weight:244.27

    Ref: TM-T85478

  • Lexitropsin
    Targetmol
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    Lexitropsin

    CAS:
    <p>Lexitropsin is a novel anticancer drug.</p>
    Formula:C20H29N5O4
    Color and Shape:Solid
    Molecular weight:403.48

    Ref: TM-T25703

  • NU-7163
    Targetmol
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    NU-7163

    CAS:
    <p>NU-7163 is a potent and selective inhibitor of ATP-competitive DNA-PK.</p>
    Formula:C18H17NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:295.33

    Ref: TM-T24559

  • ATR-IN-16
    Targetmol
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    ATR-IN-16

    CAS:
    <p>ATR-IN-16 (compound 46) is an ATR kinase inhibitor with potent anticancer effects in LoVo cells, IC50 of 410 nM.</p>
    Formula:C19H25N7O
    Color and Shape:Solid
    Molecular weight:367.45

    Ref: TM-T61432

  • Piroxantrone
    Targetmol
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    Piroxantrone

    CAS:
    <p>Piroxantrone (CI942; PD111815) is an anthrapyrazole antibiotic that disrupts DNA replication and repair, with limited cardiotoxicity and antineoplastic range.</p>
    Formula:C21H25N5O4
    Color and Shape:Solid
    Molecular weight:411.45

    Ref: TM-T68373

  • Procarbazine free base
    Targetmol
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    Procarbazine free base

    CAS:
    <p>Procarbazine: chemo drug for Hodgkin's, brain cancer; liver-activated; MAO inhibitor.</p>
    Formula:C12H19N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:221.3

    Ref: TM-T1488L

  • MLR24
    Targetmol
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    MLR24

    CAS:
    <p>MLR24 is a selective modulator of PPARγ that acts by displaying robust anti-diabetic activity.</p>
    Formula:C28H24F3NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:527.49

    Ref: TM-T24486

  • CAY10744
    Targetmol
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    CAY10744

    CAS:
    <p>CAY10744, a topoisomerase II-α inhibitor (78.9% at 20 μM), blocks cancer cell proliferation with varying IC50s and induces apoptosis in T47D cells.</p>
    Formula:C24H16ClNO2
    Color and Shape:Solid
    Molecular weight:385.84

    Ref: TM-T36195

  • Anticancer agent 75
    Targetmol
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    Anticancer agent 75

    CAS:
    <p>Anticancer agent 75: potent, selective, less toxic to kidneys than Doxorubicin by 35x, with antiplasmodial properties.</p>
    Formula:C22H24N2O
    Color and Shape:Solid
    Molecular weight:332.44

    Ref: TM-T60998

  • Givinostat hydrochloride monohydrate
    Targetmol
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    Givinostat hydrochloride monohydrate

    CAS:
    <p>Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.</p>
    Formula:C24H27N3O4·HCl·H2O
    Purity:97.97% - 99.51%
    Color and Shape:Solid
    Molecular weight:475.97

    Ref: TM-T6279

  • ZINC08438472
    Targetmol
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    ZINC08438472

    CAS:
    <p>ZINC08438472 is a selective peroxisome proliferator-activated receptors-α agonist.</p>
    Formula:C25H25NO8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:499.53

    Ref: TM-T24864

  • Topoisomerase I inhibitor 4
    Targetmol
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    Topoisomerase I inhibitor 4

    CAS:
    <p>Topoisomerase I inhibitor 4 targets cancer cells like HepG2, A549, MCF-7, HeLa with low IC50, promising for research.</p>
    Formula:C23H19FN4O
    Color and Shape:Solid
    Molecular weight:386.42

    Ref: TM-T61717

  • WEHI-150
    Targetmol
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    WEHI-150

    CAS:
    <p>WEHI-150, a mitoxantrone analog, cross-links DNA, targets methylated CpG, halts transcription, and avoids guanine N-2 interaction.</p>
    Formula:C22H30N6O4
    Color and Shape:Solid
    Molecular weight:442.51

    Ref: TM-T62582

  • Exatecan mesylate dihydrate
    Targetmol
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    Exatecan mesylate dihydrate

    CAS:
    <p>Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].</p>
    Formula:C25H30FN3O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:567.58

    Ref: TM-T78630

  • ZINC17167211
    Targetmol
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    ZINC17167211

    CAS:
    <p>ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist.</p>
    Formula:C24H17FN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:480.46

    Ref: TM-T24952

  • Ceralasertib formate
    Targetmol
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    Ceralasertib formate

    CAS:
    <p>Ceralasertib: an oral ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupts DNA repair, and triggers tumor cell apoptosis.</p>
    Formula:C21H26N6O4S
    Color and Shape:Solid
    Molecular weight:458.54

    Ref: TM-T26981

  • CAY10514
    Targetmol
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    CAY10514

    CAS:
    <p>CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.</p>
    Formula:C20H28O4
    Color and Shape:Solid
    Molecular weight:332.43

    Ref: TM-T37828

  • Ranimustine
    Targetmol
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    Ranimustine

    CAS:
    <p>Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].</p>
    Formula:C10H18ClN3O7
    Color and Shape:Solid
    Molecular weight:327.72

    Ref: TM-T60927

  • AA-CW236
    Targetmol
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    AA-CW236

    CAS:
    <p>AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).</p>
    Formula:C17H16ClF3N4O2
    Color and Shape:Solid
    Molecular weight:400.78

    Ref: TM-T26496

  • PPARδ agonist 8
    Targetmol
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    PPARδ agonist 8

    CAS:
    <p>Pparδ agonist 8 is a potent agonist of Pparδ. Pparδ agonist 8 has potential for the study of nonalcoholic fatty liver disease (NAFLD).</p>
    Formula:C25H29NO5
    Color and Shape:Solid
    Molecular weight:423.5

    Ref: TM-T62277

  • DRF 2519
    Targetmol
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    DRF 2519

    CAS:
    <p>DRF 2519 is an activator of PPAR-alpha and PPAR-gamma.</p>
    Formula:C20H18N2O5S
    Color and Shape:Solid
    Molecular weight:398.43

    Ref: TM-T27208

  • CLX 0921
    Targetmol
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    CLX 0921

    CAS:
    <p>CLX 0921, a PPAR gamma agonist, is used potentially for the treatment of type 2 diabetes.</p>
    Formula:C28H25NO7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:519.57

    Ref: TM-T27049

  • ARTD10/PARP10-IN-1
    Targetmol
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    ARTD10/PARP10-IN-1

    CAS:
    <p>ARTD10/PARP10-IN-1 is a PARP inhibitor that inhibits ARTD8/PARP14 and has anticancer and antitumour activity for the study of prostate cancer.</p>
    Formula:C12H12N2O4
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:248.23

    Ref: TM-T72553

  • Gartisertib
    Targetmol
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    Gartisertib

    CAS:
    <p>Gartisertib (VX-803) is an ATR inhibitor with anti-tumor activity, inhibiting the anti-proliferative effects induced in ccRCC cells.</p>
    Formula:C25H29F2N9O3
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:541.55

    Ref: TM-T10407

  • NSC-311068
    Targetmol
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    NSC-311068

    CAS:
    <p>NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.</p>
    Formula:C10H6N4O4S
    Color and Shape:Solid
    Molecular weight:278.24

    Ref: TM-T68773

  • Daniquidone
    Targetmol
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    Daniquidone

    CAS:
    <p>Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity for neoplasms</p>
    Formula:C15H11N3O
    Purity:98.39% - 99.52%
    Color and Shape:Solid
    Molecular weight:249.27

    Ref: TM-T68896

  • ICRF-196
    Targetmol
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    ICRF-196

    CAS:
    <p>ICRF-196 is a Topoisomerase II Inhibitor and antineoplastic agent.</p>
    Formula:C12H18N4O4
    Color and Shape:Solid
    Molecular weight:282.3

    Ref: TM-T69871