DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(13 products)
- DNA Methyltransferase(455 products)
- DNA gyrase(10 products)
- DNA-PK(48 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,422 products)
- Reverse Transcriptase(42 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(139 products)
Show 3 more subcategories
Found 1022 products of "DNA Damage/DNA Repair"
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PPARγ agonist 10
CAS:PPARγ agonist 10 (compound 33g) serves as a PPARγ agonist, enhancing insulin secretion, glucose uptake, and insulin sensitivity in βTC6 cells [1].Formula:C17H14N4O3S2Color and Shape:SolidMolecular weight:386.45DNA-PK-IN-2
CAS:DNA-PK-IN-2 is an inhibitor of the DNA-PK enzyme complex, useful in cancer research.Formula:C20H23N5O3Color and Shape:SolidMolecular weight:381.43DNA crosslinker 3 dihydrochloride
CAS:Compound 1: a DNA minor groove binder with 1.4°C ΔTm; useful in cancer research.Formula:C15H22Cl2N8OColor and Shape:SolidMolecular weight:401.29TERT activator-2
CAS:TERT activator-2 (Compound 1030) is an activator of telomerase reverse transcriptase (TERT), which enhances the expression levels of TERT within cells. TERT activator-2 is applicable to research related to cellular lifespan and telomere functions.Formula:C21H22N2O2Color and Shape:SolidMolecular weight:334.412Aleglitazar
CAS:Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.Formula:C24H23NO5SPurity:99.03%Color and Shape:SolidMolecular weight:437.51Ref: TM-T14176
1mg245.00€5mg562.00€10mg758.00€25mg1,159.00€50mg1,568.00€100mg2,110.00€1mL*10mM (DMSO)568.00€KU-60019
CAS:<p>KU-60019 is a specific inhibitor of ATM kinase (IC50: 6.3 nM).</p>Formula:C30H33N3O5SPurity:98.05% - 98.50%Color and Shape:SolidMolecular weight:547.67Simmitecan hydrochloride
CAS:Simmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can be used to study is solid tumors.Formula:C34H39ClN4O6Purity:98.20% - 98.93%Color and Shape:SolidMolecular weight:635.15BAY-8400
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM) which shows synergistic efficacy inFormula:C21H17F2N5OPurity:99.53%Color and Shape:SolidMolecular weight:393.39Ref: TM-T9498
1mg85.00€5mg156.00€10mg226.00€25mg464.00€50mg792.00€100mg1,064.00€1mL*10mM (DMSO)170.00€OBI-3424
CAS:OBI-3424, a highly selective prodrug, is converted by aldo-keto reductase family 1 member C3 (AKR1C3) to a potent DNA-alkylating agent.Formula:C21H25N4O6PPurity:98%Color and Shape:SolidMolecular weight:460.427NSC61610
CAS:NSC61610 is anti-inflammatory that activates PPARγ in vitro via LANCL2 and adenylate cyclase/cAMP-dependent pathways, thereby improving experimental colitis.Formula:C34H24N6O2Purity:98%Color and Shape:SolidMolecular weight:548.59YF438
CAS:<p>YF438 is an HDAC inhibitor that demonstrates potent anti-cancer activity both in vitro and in vivo. It inhibits the growth and metastasis of triple-negative breast cancer (TNBC) cells by blocking the interaction between HDAC and MDM2, inducing the dissociation of MDM2 from MDMX, and promoting the degradation of MDM2.</p>Formula:C23H26N4O5Color and Shape:SolidMolecular weight:438.48Phenanthriplatin
CAS:Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin Acts As a Covalent Poison of TopoisoFormula:C13H11ClN4O3PtColor and Shape:SolidMolecular weight:501.79Zabofloxacin hydrochloride
CAS:Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.Formula:C19H21ClFN5O4Purity:98%Color and Shape:SolidMolecular weight:437.86Merbarone
CAS:Merbarone is a Type II DNA topoisomerase inhibitor. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the nFormula:C11H9N3O3SColor and Shape:SolidMolecular weight:263.27SR-4370
CAS:<p>SR-4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp.</p>Formula:C17H18F2N2OPurity:99.50%Color and Shape:SolidMolecular weight:304.33Fotemustine
CAS:Fotemustine: antineoplastic, chloroethylates DNA, blocks synthesis, causes cell arrest/apoptosis, lipophilic, crosses blood-brain barrier.Formula:C9H19ClN3O5PColor and Shape:SolidMolecular weight:315.69Mavodelpar free base
CAS:<p>Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.</p>Formula:C31H30FNO5Purity:98%Color and Shape:SolidMolecular weight:515.57MDL-811
CAS:<p>MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),</p>Formula:C25H25BrCl2FN3O5S2Purity:98%Color and Shape:SolidMolecular weight:681.42Antitumor agent-104
CAS:<p>Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor cells, primarily through the inhibition of PARP1 enzyme</p>Formula:C31H33FN6O3Purity:98%Color and Shape:SolidMolecular weight:556.63Lerzeparib
CAS:<p>Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].</p>Formula:C21H20FN3O2Purity:98%Color and Shape:SolidMolecular weight:365.4ATR-IN-24
CAS:<p>ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].</p>Formula:C23H26N6O2Purity:98%Color and Shape:SolidMolecular weight:418.49PARP7-IN-16 free base
CAS:<p>PARP7-IN-16 free base is the freebase form of PARP7-IN-16. As a selective oral inhibitor of PARP-1/2/7, it demonstrates IC50 values of 0.94, 0.87, and 0.21 nM, respectively. This compound is utilized in the research of breast and prostate cancer.</p>Formula:C25H27FN4O4Color and Shape:SolidMolecular weight:466.50Ref: TM-T200703
Discontinued product
