DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(19 products)
- DNA Methyltransferase(460 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,418 products)
- Reverse Transcriptase(42 products)
- Sirtuin(90 products)
- Telomerase(34 products)
- Topoisomerase(126 products)
Show 3 more subcategories
Found 892 products of "DNA Damage/DNA Repair"
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Coralyne chloride
CAS:Coralyne chloride is a protoberberine with strong anticancer activity.Formula:C22H22ClNO4Purity:98.88%Color and Shape:SolidMolecular weight:399.87SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formula:C18H12N4OSPurity:98.72% - 99.85%Color and Shape:SolidMolecular weight:332.38Ref: TM-T1724
1mg39.00€2mg50.00€5mg79.00€1mL*10mM (DMSO)79.00€10mg120.00€25mg258.00€50mg408.00€100mg588.00€Furegrelate
CAS:FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.Formula:C15H11NO3Purity:99.71%Color and Shape:SolidMolecular weight:253.25Ref: TM-T11339L
1mg109.00€1mL*10mM (DMSO)215.00€5mg235.00€10mg349.00€25mg532.00€50mg745.00€100mg999.00€200mg1,333.00€RHPS4
CAS:RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.
Formula:C22H17F2N2·CH3O4SPurity:99.72%Color and Shape:SolidMolecular weight:458.48L-778123 hydrochloride
CAS:The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.Formula:C22H21Cl2N5OPurity:93.93% - 98.51%Color and Shape:SolidMolecular weight:442.34BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41PJ34
CAS:PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Formula:C17H17N3O2Purity:95.05% - 99.85%Color and Shape:SolidMolecular weight:295.34Pentamidine dihydrochloride
CAS:Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Formula:C19H26Cl2N4O2Purity:99.80%Color and Shape:SolidMolecular weight:413.34Ref: TM-T23132
5mg52.00€1mL*10mM (DMSO)52.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€200mg388.00€500mg642.00€PIK-75 hydrochloride
CAS:PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.Formula:C16H14BrN5O4S·HClPurity:97.82%Color and Shape:SolidMolecular weight:488.74XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Formula:C24H27N7O2Purity:98.05% - 99.89%Color and Shape:SolidMolecular weight:445.52Ref: TM-T3709
2mg44.00€5mg70.00€1mL*10mM (DMSO)84.00€10mg98.00€25mg178.00€50mg290.00€100mg480.00€500mg1,161.00€AZ20
CAS:AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.Formula:C21H24N4O3SPurity:98% - 99.69%Color and Shape:SolidMolecular weight:412.51Tretazicar
CAS:CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.Formula:C9H8N4O5Purity:99.41% - 99.7%Color and Shape:SolidMolecular weight:252.18Topovale
CAS:Topovale (ARC111) is a potent inhibitor of topoisomerase I.Formula:C23H23N3O5Purity:99.94%Color and Shape:SolidMolecular weight:421.45Hinokitiol
CAS:Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.Formula:C10H12O2Purity:99.49% - 99.98%Color and Shape:SolidMolecular weight:164.2SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Formula:C17H12ClN3O4Purity:99.6%Color and Shape:SolidMolecular weight:357.75OAC1
CAS:OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formula:C14H11N3OPurity:99.49% - 99.65%Color and Shape:SolidMolecular weight:237.26Ref: TM-T2040
1mg34.00€2mg47.00€5mg66.00€1mL*10mM (DMSO)66.00€10mg92.00€25mg164.00€50mg299.00€100mg540.00€Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Formula:C22H26O7Purity:97.97%Color and Shape:SolidMolecular weight:402.44Voxtalisib
CAS:Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.Formula:C13H14N6OPurity:98.21% - 99.69%Color and Shape:SolidMolecular weight:270.29Ref: TM-T7014
1mg35.00€2mg50.00€5mg74.00€1mL*10mM (DMSO)74.00€10mg117.00€25mg226.00€50mg364.00€100mg532.00€Genz-644282
CAS:Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.Formula:C22H21N3O5Purity:97.49%Color and Shape:SolidMolecular weight:407.42
