DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(19 products)
- DNA Methyltransferase(460 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,418 products)
- Reverse Transcriptase(42 products)
- Sirtuin(90 products)
- Telomerase(34 products)
- Topoisomerase(126 products)
Show 3 more subcategories
Found 889 products of "DNA Damage/DNA Repair"
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IndiMitecan
CAS:IndiMitecan (LMP776) is an inhibitor of topoisomerase I (Top1) with anticancer activities [1].
Formula:C25H21N3O6Purity:98.53%Color and Shape:SoildMolecular weight:459.45Semustine
CAS:Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for
Formula:C10H18ClN3O2Purity:99.70%Color and Shape:Light Yellow PowderMolecular weight:247.72CBHcy
CAS:CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.Formula:C9H17NO4SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:235.3TETi76
CAS:TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.Formula:C10H16O5Color and Shape:SolidMolecular weight:216.23Cyclophosphamide-d4
CAS:Cyclophosphamide-d4 is a deuterated compound of Cyclophosphamide. Cyclophosphamide has a CAS number of 50-18-0. Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.Formula:C7H11D4Cl2N2O2PColor and Shape:SolidMolecular weight:265.11Mirin
CAS:Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor and also inhibits Mre11-associated exonuclease activity.Mirin induces cell cycle arrest in G1 phase.Formula:C10H8N2O2SPurity:99.24%Color and Shape:SolidMolecular weight:220.25Ref: TM-T60273
2mg34.00€5mg46.00€1mL*10mM (DMSO)49.00€10mg67.00€25mg112.00€50mg168.00€100mg239.00€200mg353.00€Palmitoyllactic acid
CAS:Palmitoyllactic acid is a long-chain fatty acid.Formula:C19H36O4Color and Shape:SolidMolecular weight:328.49ART0380
CAS:ART0380 is a potent, antitumor, selective, orally available, ATP-competitive ATR kinase inhibitor for the study of ataxia telangiectasia mutated (ATM) cancer.
Formula:C18H24N6O2SPurity:99.06% - >99.99%Color and Shape:SolidMolecular weight:388.49Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFormula:C20H24O7SPurity:99.95%Color and Shape:SolidMolecular weight:408.47Ref: TM-T17044
1mg43.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg130.00€25mg241.00€50mg405.00€100mg632.00€200mg875.00€MY-1B
CAS:MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.Formula:C22H18BrN3O2Purity:99.81% - >99.99%Color and Shape:SoildMolecular weight:436.37-Methyladenine
CAS:7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents.Formula:C6H7N5Purity:99.90%Color and Shape:SolidMolecular weight:149.15ICRF-193
CAS:ICRF-193 is a DNA topoisomerase II inhibitor.Formula:C12H18N4O4Color and Shape:SolidMolecular weight:282.3KRP-297
CAS:KRP297 is a PPAR agonist potentially for the treatment of type 2 diabetes and dyslipidemia.Formula:C20H17F3N2O4SColor and Shape:SolidMolecular weight:438.42DNA-PK-IN-1
CAS:DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.Formula:C23H26N8O2Color and Shape:SolidMolecular weight:446.5DNA-PK-IN-3
CAS:DNA-PK-IN-3 is a potent DNA-PK inhibitor, enhancing radio/chemotherapy and reducing tumors with limited side effects.Formula:C19H19N9OColor and Shape:SolidMolecular weight:389.41Guadecitabine
CAS:Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.Formula:C18H24N9O10PPurity:98%Color and Shape:SolidMolecular weight:557.41MLR24
CAS:MLR24 is a selective modulator of PPARγ that acts by displaying robust anti-diabetic activity.Formula:C28H24F3NO6Purity:98%Color and Shape:SolidMolecular weight:527.49CAY10514
CAS:CAY10514 is an aromatic analog of 8(S)-HETE. It acts as a dual agonist of PPARα and PPARγ with EC50 values of 0.173 and 0.642 μM, respectively.Formula:C20H28O4Color and Shape:SolidMolecular weight:332.43Naveglitazar racemate
CAS:Naveglitazar racemate is the racemate of Naveglitazar.Formula:C25H26O6Purity:98%Color and Shape:SolidMolecular weight:422.47Ranimustine
CAS:Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].Formula:C10H18ClN3O7Color and Shape:SolidMolecular weight:327.72
