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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 961 products of "DNA Damage/DNA Repair"

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  • Procainamide

    CAS:
    <p>Procainamide: DNMT1 inhibitor, Class 1A antiarrhythmic, promising for cancer and arrhythmia research.</p>
    Formula:C13H21N3O
    Purity:99.92% - 99.92%
    Color and Shape:Solid
    Molecular weight:235.33
  • L82

    CAS:
    <p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>
    Formula:C11H8ClN5O4
    Purity:97.45% - 98.91%
    Color and Shape:Solid
    Molecular weight:309.67
  • BTB09089

    CAS:
    <p>BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production</p>
    Formula:C14H12Cl2N4OS2
    Purity:99.78%
    Color and Shape:Soild
    Molecular weight:387.31
  • BRD 9757

    CAS:
    <p>BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).</p>
    Formula:C6H9NO2
    Purity:98.39% - 99.87%
    Color and Shape:Solid
    Molecular weight:127.14
  • SIRT6-IN-5

    CAS:
    <p>SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.</p>
    Formula:C19H14N2O6
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:366.32
  • HDAC8-IN-20a

    CAS:
    <p>HDAC8-IN-20a (HDAC8 inhibitor-20a) is a potent and selective HDAC8 inhibitor with an IC50 of 27 nM.</p>
    Formula:C15H15NO4
    Purity:98.24% - 99.22%
    Color and Shape:Solid
    Molecular weight:273.28
  • Suksdorfin

    CAS:
    <p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>
    Formula:C21H24O7
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:388.41
  • Bobcat339 hydrochloride

    CAS:
    <p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>
    Formula:C16H13Cl2N3O
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:334.2
  • Alalevonadifloxacin

    CAS:
    <p>Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa.</p>
    Formula:C23H30FN3O8S
    Purity:99.75% - 99.82%
    Color and Shape:Soild
    Molecular weight:527.56
  • Pegamotecan

    CAS:
    <p>Pegamotecan (PEG-camptothecin) is a topoisomerase I (TOP1) inhibitor with anticancer activity, and it is used in the treatment of esophageal, non-small cell</p>
    Formula:C52H48N6O14
    Purity:96.40% - 97.83%
    Color and Shape:Solid
    Molecular weight:980.984
  • Miriplatin hydrate

    CAS:
    Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC).
    Formula:C34H70N2O5Pt
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:782.01
  • BRD6688

    CAS:
    <p>BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes</p>
    Formula:C16H18N4O
    Purity:97.53%
    Color and Shape:Solid
    Molecular weight:282.34
  • PARP10-IN-2

    CAS:
    <p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>
    Formula:C14H10N2O2
    Purity:99.27%
    Color and Shape:Solid
    Molecular weight:238.24
  • Tenifatecan

    CAS:
    <p>Tenifatecan (SN2310) is a highly lipophilic preparation of 7-ethyl-10-hydroxycamptothecin (SN) with potential antitumor activity.</p>
    Formula:C55H72N2O9
    Purity:99.58% - 99.82%
    Color and Shape:Solid
    Molecular weight:905.17
  • SS-208

    CAS:
    <p>SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.</p>
    Formula:C13H11Cl2N3O4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:344.15
  • (R)-(-)-Rolipram

    CAS:
    <p>(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.</p>
    Formula:C16H21NO3
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:275.34
  • Givinostat hydrochloride

    CAS:
    <p>Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.</p>
    Formula:C24H28ClN3O4
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:457.95
  • EB-47

    CAS:
    <p>EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).</p>
    Formula:C24H27N9O6
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:537.53
  • CEP-9722

    CAS:
    <p>CEP-9722 is a PARP-1 and PARP-2 inhibitor with anticancer activity and is used in the study of ovarian cancer.</p>
    Formula:C24H26N4O3
    Purity:98.38% - 98.56%
    Color and Shape:Solid
    Molecular weight:418.49
  • ACY-957

    CAS:
    <p>ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.</p>
    Formula:C24H23N5OS
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:429.54