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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 961 products of "DNA Damage/DNA Repair"

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  • OUL232
    Targetmol
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    OUL232

    CAS:
    <p>OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.</p>
    Formula:C10H10N4O2S
    Purity:99.04%
    Color and Shape:Solid
    Molecular weight:250.28

    Ref: TM-T73496

  • ACY-1083
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    ACY-1083

    CAS:
    <p>ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced peripheral neuropathy.</p>
    Formula:C17H18F2N4O2
    Purity:99.19% - 99.43%
    Color and Shape:Solid
    Molecular weight:348.35

    Ref: TM-T10244

  • BRD4097
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    BRD4097

    CAS:
    <p>BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve</p>
    Formula:C16H17N3O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:283.33

    Ref: TM-T30579

  • L-783483
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    L-783483

    CAS:
    <p>L-783483 is an agonist of PPAR.</p>
    Formula:C22H21ClF3NO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:487.92

    Ref: TM-T27784

  • SU-11752
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    SU-11752

    CAS:
    <p>SU-11752 selectively inhibits DNA-PK by competing with ATP, enhances ionizing radiation sensitivity without affecting cell cycle or ATM activity.</p>
    Formula:C26H27N3O5S
    Color and Shape:Solid
    Molecular weight:493.57

    Ref: TM-T68870

  • Makaluvamine A
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    Makaluvamine A

    CAS:
    <p>Makaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.</p>
    Formula:C11H11N3O
    Color and Shape:Solid
    Molecular weight:201.22

    Ref: TM-T70592

  • Epigenetic factor-IN-1
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    Epigenetic factor-IN-1

    CAS:
    <p>Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.</p>
    Formula:C32H34FN5O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:667.77

    Ref: TM-T82458

  • KD-3010
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    KD-3010

    CAS:
    <p>KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.</p>
    Formula:C30H33F3N2O8S2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:670.72

    Ref: TM-T11747

  • PARP7-IN-15
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    PARP7-IN-15

    CAS:
    <p>PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and demonstrates antitumor activity [1].</p>
    Formula:C23H24F6N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:562.46

    Ref: TM-T81542

  • KRP-101
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    KRP-101

    CAS:
    <p>KRP-101, a PPARɑ agonist, is used potentially for the treatment of diabetes and hyperlipidaemia.</p>
    Formula:C26H26FNO5
    Color and Shape:Solid
    Molecular weight:451.49

    Ref: TM-T27746

  • ATM-IN-1
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    ATM-IN-1

    CAS:
    <p>ATM-IN-1 is a potent inhibitor of ATM. ATM-IN-1 has shown research potential in cancer and neurological diseases.</p>
    Formula:C30H36N6O3
    Color and Shape:Solid
    Molecular weight:528.65

    Ref: TM-T63714

  • NH2-methylpropanamide-Exatecan TFA
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    NH2-methylpropanamide-Exatecan TFA

    CAS:
    <p>Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.</p>
    Formula:C30H30F4N4O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:634.58

    Ref: TM-T77889

  • CM-675
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    CM-675

    CAS:
    <p>CM-675 is a dual inhibitor of phosphodiesterase 5 (PDE5) and class I histone deacetylases (IC50s: 114 nM and 673 nM for PDE5 and HDAC1) with the potential to</p>
    Formula:C31H32N6O3
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:536.62

    Ref: TM-T10841

  • 7-Deaza-2′-deoxyguanosine 5′-triphosphate
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    7-Deaza-2′-deoxyguanosine 5′-triphosphate

    CAS:
    <p>7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].</p>
    Formula:C11H17N4O13P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.19

    Ref: TM-T83248

  • Tankyrase-IN-5
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    Tankyrase-IN-5

    CAS:
    <p>Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with half-maximal inhibitory</p>
    Formula:C17H18N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:282.34

    Ref: TM-T79026

  • HDAC6-IN-21
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    HDAC6-IN-21

    CAS:
    <p>HDAC6-IN-21 (compound 13) is an irreversible inhibitor of histone deacetylase 6 (HDAC6) [1].</p>
    Formula:C14H13F2N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:321.28

    Ref: TM-T82226

  • SIRT6-IN-3
    Targetmol
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    SIRT6-IN-3

    CAS:
    <p>SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and prompts</p>
    Formula:C21H30Br3ClN6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.73

    Ref: TM-T79689

  • ATR-IN-21
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    ATR-IN-21

    CAS:
    <p>ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 of less than 1000 nM [1].</p>
    Formula:C23H27N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:417.51

    Ref: TM-T79031

  • 9-Chloromethyl-10-hydroxy-11-F-Camptothecin
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    9-Chloromethyl-10-hydroxy-11-F-Camptothecin

    CAS:
    <p>9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential</p>
    Formula:C22H18ClFN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:428.84

    Ref: TM-T79883

  • PR-104A
    Targetmol
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    PR-104A

    CAS:
    <p>PR-104A is a hypoxia-targeted anticancer agent.</p>
    Formula:C14H19BrN4O9S
    Color and Shape:Solid
    Molecular weight:499.29

    Ref: TM-T28447