DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(13 products)
- DNA Methyltransferase(455 products)
- DNA gyrase(11 products)
- DNA-PK(48 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,421 products)
- Reverse Transcriptase(42 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(141 products)
Show 3 more subcategories
Found 1033 products of "DNA Damage/DNA Repair"
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Hippeastrine
CAS:<p>Hippeastrine is an alkaloid that inhibits Top I dose-dependently with a 7.25 μg/mL IC50 and has anticancer properties.</p>Formula:C17H17NO5Color and Shape:SolidMolecular weight:315.32Multi-target kinase inhibitor 4
<p>Multi-target kinase inhibitor 4 (Compound 2) is a PI3K/DNA-PK inhibitor and a potent chemosensitizer that enhances the number of DNA double-strand breaks induced by Doxorubicin. It serves as an effective multidrug resistance (MDR) inhibitor, demonstrating inhibitory activity against P-glycoprotein (P-gp) mediated drug efflux. Multi-target kinase inhibitor 4 can be encapsulated in PEG-coated lipid nanoparticles.</p>Color and Shape:Odour SolidCP 84364
CAS:CP 84364 is a metabolite of CP-80794.Formula:C14H18N2O4Color and Shape:SolidMolecular weight:278.3017-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Formula:C22H30O3Color and Shape:SolidMolecular weight:342.479DB1255 2TFA
DB1255 2TFA is an ERG/DNA binding inhibitor with an unusual and potent monomer binding pattern at the minor groove site for the study of genetic disorders.Formula:C26H20F6N4O4S2Purity:98.32%Color and Shape:SolidMolecular weight:630.58Saroglitazar Magnesium
CAS:<p>Saroglitazar Magnesium: a PPAR agonist, strong on PPARα (EC50 0.65pM), moderate on PPARγ (EC50 3nM).</p>Formula:C50H56MgN2O8S2Purity:98.1%Color and Shape:SolidMolecular weight:901.43GJ071 oxalate
CAS:GJ071 oxalate is a Nonsense suppressor that induces readthrough by inserting amino acids at premature termination codons.Formula:C20H29N3O7SPurity:99.97%Color and Shape:SolidMolecular weight:455.53Ref: TM-T31932
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)170.00€(±)4(5)-DiHDPA lactone
CAS:(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495HDAC6-IN-50
<p>HDAC6-IN-50 (Compound 4) is an effective inhibitor of HDAC6 with an IC50 value of 35 nM. It is utilized in the study of Parkinson's disease (PD) and Alzheimer's disease (AD).</p>Color and Shape:Odour SolidTRF1-TIN2 interaction-IN-1
TRF1-TIN2 interaction-IN-1 (Compound 40) is an inhibitor of the TRF1-TIN2 interaction. It binds to the TRFH domain of TRF1 (KD= 29 μM) and competitively inhibits the binding of the TIN2 peptide (IC50= 67 μM). By occupying a hotspot at the TRF1-TIN2 interface, TRF1-TIN2 interaction-IN-1 disrupts the interaction between TRF1 and TIN2. This compound can remove TRF1 from the shelterin complex, making it useful for research on shelterin-related cancers.Formula:C19H18O6SColor and Shape:SolidMolecular weight:374.41VH 032 amide-PEG1-acid
CAS:VHL ligand for PROTAC R&D; E3 ligase with PEG1 linker and carboxylic acid for target conjugation.Formula:C28H38N4O7SColor and Shape:SolidMolecular weight:574.69Antitumor agent-63
CAS:Compound 40, a non-toxic 20(S)-O-CPT glycoconjugate, is stable, with low Topo I inhibition.Formula:C38H46N4O18Color and Shape:SolidMolecular weight:846.79Methylation Compound Library
xnum methylation-related compounds that can be used for high-throughput and high-content screening.Color and Shape:Odour SolidRef: TM-L3510
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireSIRT-IN-5
SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.Color and Shape:Odour SolidN-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide
CAS:<p>N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide: binds CB1 (Ki=365 nM), activates PPARα (EC50=698 nM), reduces rat food intake, no FAAH inhibition.</p>Formula:C27H45NO3Color and Shape:SolidMolecular weight:431.661PDPH Crosslinker
CAS:PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.Formula:C8H11N3OS2Color and Shape:SolidMolecular weight:229.32HDAC-IN-78
HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.Color and Shape:Odour SolidGW 1929 hydrochloride
CAS:Oral PPARγ agonist with pEC50 of 8.05; low affinity for PPARα, PPARδ. Reduces blood glucose, fatty acids, triglycerides in vivo.Formula:C30H30ClN3O4Color and Shape:SolidMolecular weight:532.04Banoxantrone-d12 dihydrochloride
CAS:Banoxantrone D12, a deuterium-labeled version, transforms into DNA-binding topoisomerase II inhibitor AQ4 upon reduction.Formula:C22H30Cl2N4O6Purity:98%Color and Shape:SolidMolecular weight:529.48Corydamine
Corydamine is a useful organic compound for research related to life sciences and the catalog number is T124768.Formula:C20H18N2O4Color and Shape:SolidMolecular weight:350.374
