DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(74 products)
- DNA Alkylation(21 products)
- DNA Methyltransferase(472 products)
- DNA gyrase(6 products)
- DNA-PK(50 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(506 products)
- Reverse Transcriptase(41 products)
- Sirtuin(91 products)
- Telomerase(33 products)
- Topoisomerase(129 products)
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Found 850 products for "DNA Damage/DNA Repair".
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DMT-dG(ib) Phosphoramidite
CAS:DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.Formula:C44H54N7O8PPurity:99.21%Color and Shape:SolidMolecular weight:839.92DNA Damage & Repair Compound Library
A unique collection of xnum DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
Color and Shape:Odour SolidTet1
CAS:Tet1 is a peptide with the sequence HLNILSTLWKYRC. It specifically binds to the neuronal ganglioside receptor GT1b, which gives it the ability to target neurons. Tet1 is suitable for research related to drug delivery.Formula:C76H119N21O18SColor and Shape:SolidMolecular weight:1646.95ARN24139
ARN24139: a topoisomerase II poison; IC50=7.3μM. Inhibits DU145, HeLa, A549 cell growth; IC50s=4.7, 3.8, 3.1μM.Color and Shape:SolidHippeastrine Hydrobromide
CAS:Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.Formula:C17H18BrNO5Color and Shape:SolidMolecular weight:396.237AZD-5099
CAS:AZD-5099 is a DNA gyrase modulator potentially for the treatment of bacterial infection.Formula:C21H27Cl2N5O6SColor and Shape:SolidMolecular weight:548.44Methylation Compound Library
xnum methylation-related compounds that can be used for high-throughput and high-content screening.Color and Shape:Odour SolidRef: TM-L3510
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireBerzosertib
CAS:Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM). Berzosertib has antitumor activity. Cost-effective and quality-assured.Formula:C24H25N5O3SPurity:97.34% - >99.99%Color and Shape:SolidMolecular weight:463.55Ref: TM-T2669
1mg34.00€5mg71.00€1mL*10mM (DMSO)73.00€10mg96.00€25mg146.00€50mg213.00€100mg340.00€200mg497.00€500mg790.00€(±)9-HEPE
CAS:(±)9-HEPE is produced by non-enzymatic oxidation of EPA.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457PPARγ/GR modulator 1
PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibitsFormula:C14H10FNO4Color and Shape:SolidMolecular weight:275.23Gimatecan HCl
Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.Formula:C25H26ClN3O5Purity:97.04%Color and Shape:SoildMolecular weight:483.94Topoisomerase I/II inhibitor 5
TopoisomeraseI/II inhibitor 5 (compound 1) stabilizes G4 structures through binding and concurrently inhibits the relaxation activities of TopoI and II.Color and Shape:Odour SolidIC 86621
CAS:IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.Formula:C12H15NO3Purity:99.68%Color and Shape:SolidMolecular weight:221.25CP 84364
CAS:CP 84364 is a metabolite of CP-80794.Formula:C14H18N2O4Color and Shape:SolidMolecular weight:278.301-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC (10 mg/mL in Chloroform)
CAS:Phospholipid with stearic and docosahexaenoic acids used in membrane studies; decreases in ALS mouse model.Formula:C48H84NO8PColor and Shape:White LiquidMolecular weight:834.16Larsucosterol Ammonium salt
CAS:Larsucosterol ammonium salt is a derivative of 25HC3S. It is a DNMT inhibitor, a LXR antagonist, an endogenous epigenetic modulator of lipid metabolism.Formula:C27H49NO5SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:499.75ACT-387042
CAS:ACT-387042 is a Bacterial Topoisomerase Inhibitor, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.Formula:C23H26FN5O4SColor and Shape:SolidMolecular weight:487.55Antitumor agent-63
CAS:Compound 40, a non-toxic 20(S)-O-CPT glycoconjugate, is stable, with low Topo I inhibition.Formula:C38H46N4O18Color and Shape:SolidMolecular weight:846.7917-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS:DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495TRF1-TIN2 interaction-IN-1
TRF1-TIN2 interaction-IN-1 (Compound 40) is an inhibitor of the TRF1-TIN2 interaction. It binds to the TRFH domain of TRF1 (KD= 29 μM) and competitively inhibits the binding of the TIN2 peptide (IC50= 67 μM). By occupying a hotspot at the TRF1-TIN2 interface, TRF1-TIN2 interaction-IN-1 disrupts the interaction between TRF1 and TIN2. This compound can remove TRF1 from the shelterin complex, making it useful for research on shelterin-related cancers.Formula:C19H18O6SColor and Shape:SolidMolecular weight:374.41
