DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
Sirt1/2-IN-4
Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 …
Formula:
C21H20N4O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
440.54
Ref: TM-T79565
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Berzosertib
CAS:1232416-25-9
Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM). …
Formula:
C24H25N5O3S
Purity:
100% - 99.7%
Color and Shape:
Solid
Molecular weight:
463.55
Ref: TM-T2669
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 351.00 € | ||
| 200mg | 513.00 € | ||
| 500mg | 814.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
AuM1Phe
AuM1Phe, an N-heterocyclic carbene (NHC) metal complex, inhibits both human topoisomerase I activity and actin …
Purity:
98%
Ref: TM-T82934
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
BRD 4354 ditrifluoroacetate
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and …
Formula:
C25H25ClF6N4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
610.93
Ref: TM-T10602
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
YCH1899
YCH1899, an orally active PARP inhibitor, demonstrates potent inhibition of PARP1/2 with an IC50 of …
Formula:
C25H18BrFN6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
549.35
Ref: TM-T79667
| 1mg | 121.00 € | ||
| 5mg | 553.00 € | ||
| 10mg | 1,044.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
HDAC8-IN-5
HDAC8-IN-5 (Compound 6a), with an inhibitory concentration (IC50) of 28 nM, is a potent HDAC8 …
Formula:
C12H11N3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
277.23
Ref: TM-T78861
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Methyl methanesulfonate
CAS:66-27-3
Methyl methanesulfonate alkylates adenine and guanine, causing base mismatches and replication issues.
Formula:
C2H6O3S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
110.13
Ref: TM-T9985
| 10g | 34.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
J27644
J27644 is a potent HDAC (histone deacetylase) inhibitor that mitigates TGF-β (transforming growth factor beta)-induced …
Formula:
C16H12ClN3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
345.74
Ref: TM-T79543
| 1mg | 603.00 € | ||
| 5mg | 2,409.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
PARP-1/2-IN-2
PARP-1/2-IN-2-IN-1 (Compound 12e) effectively inhibits PARP1/2 and CDK12 with IC 50 values of 34 nM, …
Formula:
C25H23IN8O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
610.41
Ref: TM-T78787
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
HDAC6-IN-17
HDAC6-IN-17 (compound 5b) is a potent inhibitor of HDAC6, exhibiting IC50 values of 150 nM …
Formula:
C22H17N3O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
403.45
Ref: TM-T78769
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Tallimustine HCl
CAS:118438-45-2
Tallimustine HCl, an AT-specific alkylating agent, treats leukemia in immunodeficiency mouse models.
Formula:
C32H39Cl3N10O4
Purity:
98.52%
Color and Shape:
Soild
Molecular weight:
734.08
Ref: TM-T68151L
| 1mg | 183.00 € | ||
| 5mg | 400.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,268.00 € | ||
| 100mg | 1,706.00 € | ||
| 500mg | 3,418.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
GK444
GK444 (Compound 15a), a selective HDAC1/2 inhibitor with IC50 values of 100 nM and 92 …
Purity:
98%
Ref: TM-T82314
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Oxaquin TEA
Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that …
Formula:
C37H48F2N5O11P
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
807.77
Ref: TM-T12337L
| 1mg | 182.00 € | ||
| 5mg | 402.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,263.00 € | ||
| 100mg | 1,698.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
HDAC-IN-52
CAS:2075787-77-6
HDAC-IN-52: Pyridine-based inhibitor for HDAC1/2/3/10 with IC50s 0.189-0.446 μM, used in cancer studies.
Formula:
C24H20N4O2
Purity:
98.5%
Color and Shape:
Solid
Molecular weight:
396.44
Ref: TM-T67878
| 1mg | 182.00 € | ||
| 5mg | 409.00 € | ||
| 10mg | 606.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,299.00 € | ||
| 100mg | 1,735.00 € | ||
| 500mg | 3,463.00 € | ||
| 1mL*10mM (DMSO) | 458.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Garcinone C
CAS:76996-27-5
Garcinone C, a xanthone from Garcinia oblongifolia, is anti-inflammatory, promotes healing, and may fight some …
Formula:
C23H26O7
Purity:
98.93%
Color and Shape:
Solid
Molecular weight:
414.45
Ref: TM-TN1673
| 1mg | 45.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
HSP70/SIRT2-IN-1
HSP70/SIRT2-IN-1 (Compound 2a) serves as a dual inhibitor targeting both SIRT2 and HSP70, exhibiting an …
Purity:
98%
Ref: TM-T82168
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Ref: TM-T81393
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
4β-Hydroxywithanolide E
CAS:54334-04-2
4bHWE inhibits colon cancer growth, alters splicing, is anti-inflammatory, aids in diabetes/obesity, and may be …
Formula:
C28H38O8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
502.604
Ref: TM-TN3070
| 1mg | 1,802.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Et-29
CAS:2166487-23-4
Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.
Formula:
C34H46N6O6S
Purity:
98.69%
Color and Shape:
Solid
Molecular weight:
666.83
Ref: TM-T35347
| 1mg | 68.00 € | ||
| 5mg | 146.00 € | ||
| 10mg | 229.00 € | ||
| 25mg | 388.00 € | ||
| 50mg | 552.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Dihydro-5-azacytidine
CAS:62488-57-7
Dihydro-5-azacytidine (DHAC) is a nucleoside analog that interrupts DNA methylation by integrating into DNA. It …
Formula:
C8H14N4O5
Purity:
100%
Color and Shape:
Solid
Molecular weight:
246.22
Ref: TM-T40713
| 25mg | 1,422.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
