DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
360A
CAS:794458-56-3
360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 …
Formula:
C27H23N5O2
Purity:
98.68%
Color and Shape:
Solid
Molecular weight:
449.5
Ref: TM-T7409
| 1mg | 96.00 € | ||
| 2mg | 150.00 € | ||
| 5mg | 210.00 € | ||
| 10mg | 320.00 € | ||
| 25mg | 530.00 € | ||
| 50mg | 745.00 € | ||
| 100mg | 1,064.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Lomeguatrib
CAS:192441-08-0
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase …
Formula:
C10H8BrN5OS
Purity:
99.08% - 99.62%
Color and Shape:
Solid
Molecular weight:
326.17
Ref: TM-T2495
| 5mg | 50.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 283.00 € | ||
| 500mg | 705.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Nexturastat A
CAS:1403783-31-2
Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is …
Formula:
C19H23N3O3
Purity:
98.98% - 99.57%
Color and Shape:
Solid
Molecular weight:
341.4
Ref: TM-T1819
| 1mg | 69.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 303.00 € | ||
| 100mg | 449.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
PI-1840
CAS:1401223-22-0
PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on …
Formula:
C22H26N4O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
394.47
Ref: TM-T6941
| 5mg | 38.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 329.00 € | ||
| 200mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 38.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
ETP-45658
CAS:1198357-79-7
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 …
Formula:
C16H17N5O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T25399
| 1mg | 52.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 747.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
NSC 3852
CAS:3565-26-2
NSC 3852 is a potent inhibitor of histone deacetylase.
Formula:
C9H6N2O2
Purity:
98.44%
Color and Shape:
Slightly Yellow To Yellow-Green Powder
Molecular weight:
174.16
Ref: TM-T7691
| 25mg | 56.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 124.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Dactolisib
CAS:915019-65-7
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 …
Formula:
C30H23N5O
Purity:
97.64% - 99.85%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T2235
| 25mg | 47.00 € | ||
| 50mg | 57.00 € | ||
| 100mg | 70.00 € | ||
| 200mg | 106.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Pimelic diphenylamide 106
CAS:937039-45-7
Pimelic diphenylamide 106 (RGFA-8) is a slow, tight-binding inhibitor of class I HDAC, showing no …
Formula:
C20H25N3O2
Purity:
95.25% - 99.28%
Color and Shape:
Solid
Molecular weight:
339.43
Ref: TM-T3193
| 10mg | 47.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 116.00 € | ||
| 100mg | 205.00 € | ||
| 200mg | 303.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Rac-Belinostat
CAS:414864-00-9
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
Formula:
C15H14N2O4S
Purity:
99.67% - 99.96%
Color and Shape:
Solid
Molecular weight:
318.35
Ref: TM-T1852
| 10mg | 44.00 € | ||
| 25mg | 65.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 128.00 € | ||
| 200mg | 197.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
(Z)-Mirin
CAS:1198097-97-0
(Z)-Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
Formula:
C10H8N2O2S
Purity:
98.37% - 99.96%
Color and Shape:
Solid
Molecular weight:
220.25
Ref: TM-T3134
| 5mg | 55.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 416.00 € | ||
| 200mg | 542.00 € | ||
| 500mg | 872.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
TMP269
CAS:1314890-29-3
TMP269: Class IIa HDAC inhibitor; HDAC4 IC50=157 nM, HDAC5 IC50=97 nM, HDAC7 IC50=43 nM, HDAC9 …
Formula:
C25H21F3N4O3S
Purity:
98% - 99.06%
Color and Shape:
Solid
Molecular weight:
514.52
Ref: TM-T1857
| 2mg | 72.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 161.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 470.00 € | ||
| 100mg | 567.00 € | ||
| 200mg | 817.00 € | ||
| 500mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 122.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Amonafide
CAS:69408-81-7
Amonafide (NSC-308847, AS1413) causes DNA breaks via topoisomerase II, not topoisomerase I.
Formula:
C16H17N3O2
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
283.33
Ref: TM-T6336
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 467.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
A-966492
CAS:934162-61-5
A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 …
Formula:
C18H17FN4O
Purity:
98.53% - 99.27%
Color and Shape:
Solid
Molecular weight:
324.35
Ref: TM-T6366
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 275.00 € | ||
| 100mg | 394.00 € | ||
| 200mg | 560.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
6-AZATHYMINE
CAS:932-53-6
6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.
Formula:
C4H5N3O2
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
127.1
Ref: TM-T8648
| 50mg | 40.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 97.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
SIRT7 inhibitor 97491
CAS:1807758-81-1
SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 …
Formula:
C15H12ClN3O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
285.73
Ref: TM-T39233
| 1mg | 96.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 597.00 € | ||
| 50mg | 852.00 € | ||
| 100mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 259.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
ACY-775
CAS:1375466-18-4
ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).
Formula:
C17H19FN4O2
Purity:
95.99% - 97.67%
Color and Shape:
Solid
Molecular weight:
330.36
Ref: TM-TQ0074
| 5mg | 50.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 353.00 € | ||
| 200mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Satraplatin
CAS:129580-63-8
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and …
Formula:
C10H22Cl2N2O4Pt
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
500.28
Ref: TM-T7221
| 1mg | 99.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 615.00 € | ||
| 50mg | 847.00 € | ||
| 100mg | 1,169.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
CRT0044876
CAS:6960-45-8
CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.
Formula:
C9H6N2O4
Purity:
98.27% - 98.98%
Color and Shape:
Brown Powder
Molecular weight:
206.15
Ref: TM-T6456
| 25mg | 39.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 69.00 € | ||
| 500mg | 145.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
Splitomicin
CAS:5690-03-9
Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, …
Formula:
C13H10O2
Purity:
98.64% - 99.11%
Color and Shape:
Solid
Molecular weight:
198.22
Ref: TM-T6678
| 5mg | 48.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 325.00 € | ||
| 200mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
azd1390
CAS:2089288-03-7
AZD1390: Potent ATM inhibitor (IC50: 0.78 nM), >10,000-fold selectivity vs. PIKK enzymes.
Formula:
C27H32FN5O2
Purity:
97.41% - 99.38%
Color and Shape:
Solid
Molecular weight:
477.57
Ref: TM-T5175
| 1mg | 88.00 € | ||
| 2mg | 107.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 464.00 € | ||
| 50mg | 590.00 € | ||
| 100mg | 757.00 € |
Estimated delivery in United States, on Thursday 3 Apr 2025
