Topoisomerase
Topoisomerases are enzymes that regulate the topology of DNA during processes such as replication, transcription, and chromosome segregation by introducing transient breaks into the DNA strands to relieve torsional stress. Topoisomerase inhibitors interfere with this process, leading to the accumulation of DNA breaks and the induction of cell death, particularly in rapidly dividing cells. These inhibitors are widely used as chemotherapeutic agents in cancer treatment. At CymitQuimica, we offer a broad range of high-quality topoisomerase inhibitors to support your research in DNA replication, cancer therapy, and cell cycle regulation.
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Daunorubicin hydrochloride
CAS:23541-50-6
Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA …
Formula:
C27H29NO10·HCl
Purity:
96.21% - 99.53%
Color and Shape:
Cancer Drug
Molecular weight:
563.99
Ref: TM-T1511
| 5mg | 42.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 188.00 € | ||
| 200mg | 296.00 € | ||
| 500mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Moxifloxacin hydrochloride
CAS:186826-86-8
Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria …
Formula:
C21H25ClFN3O4
Purity:
100% - 99.91%
Color and Shape:
Solid
Molecular weight:
437.89
Ref: TM-T0331
| 25mg | 42.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 87.00 € | ||
| 200mg | 119.00 € | ||
| 500mg | 177.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Nalidixic acid sodium salt
CAS:3374-05-8
Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.
Formula:
C12H11N2NaO3
Purity:
100% - 99.94%
Color and Shape:
White To Off-White Powder
Molecular weight:
254.22
Ref: TM-T0909L
| 100mg | 41.00 € | ||
| 200mg | 52.00 € | ||
| 500mg | 91.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Gatifloxacin
CAS:112811-59-3
Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.
Formula:
C19H22FN3O4
Purity:
99.96%
Color and Shape:
White Powder
Molecular weight:
375.39
Ref: TM-T1293
| 1g | 52.00 € | ||
| 500mg | 48.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Pefloxacin Mesylate Dihydrate
CAS:149676-40-4
Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting …
Formula:
C17H20FN3O3·CH4O3S·2H2O
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
465.49
Ref: TM-T0425L
| 1g | 93.00 € | ||
| 100mg | 34.00 € | ||
| 200mg | 50.00 € | ||
| 500mg | 72.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Epirubicin hydrochloride
CAS:56390-09-1
Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective …
Formula:
C27H30ClNO11
Purity:
99.59% - 99.79%
Color and Shape:
Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
Molecular weight:
579.98
Ref: TM-T0125
| 2mg | 39.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 319.00 € | ||
| 500mg | 768.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Lomefloxacin hydrochloride
CAS:98079-52-8
Lomefloxacin hydrochloride (Okacyn) is a fluoroquinolone that inhibits DNA replication in bacteria, causing cell death.
Formula:
C17H20ClF2N3O3
Purity:
99.43% - 99.75%
Color and Shape:
White Powder
Molecular weight:
387.81
Ref: TM-T1625
| 100mg | 57.00 € | ||
| 500mg | 93.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Lomefloxacin
CAS:98079-51-7
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
Formula:
C17H19F2N3O3
Purity:
99.26%
Color and Shape:
Off-White To Yellow Crystals
Molecular weight:
351.35
Ref: TM-T1444
| 25mg | 45.00 € | ||
| 100mg | 59.00 € | ||
| 200mg | 73.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Daun02
CAS:290304-24-4
Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.
Formula:
C41H44N2O20
Purity:
98%
Color and Shape:
Solid
Molecular weight:
884.79
Ref: TM-T15054
| 25mg | 705.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Topoisomerase II inhibitor 13
CAS:451515-89-2
WAY-323966 suppresses Topo II, strongly halts HL-60/MX2 cancer cell growth, resists Topo II toxicity.
Formula:
C22H23N9
Purity:
98.4%
Color and Shape:
Soild
Molecular weight:
413.48
Ref: TM-T67899
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 304.00 € | ||
| 100mg | 454.00 € | ||
| 500mg | 984.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
TAK1 inhibitor
CAS:1326712-16-6
TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with …
Formula:
C22H19ClN6O2S
Purity:
98%
Color and Shape:
Soild
Molecular weight:
466.94
Ref: TM-T67909
| 5mg | 2,320.00 € | ||
| 50mg | 4,676.00 € | ||
| 100mg | 6,573.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Garenoxacin
CAS:194804-75-6
Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative …
Formula:
C23H20F2N2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
426.41
Ref: TM-T7179
| 5mg | 261.00 € | ||
| 10mg | 392.00 € | ||
| 25mg | 835.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
(rac)-Exatecan Intermediate 1
CAS:102978-40-5
(rac)-Exatecan Intermediate 1 is a camptothecin derivative, a potential topoisomerase I inhibitor, used in tumor …
Formula:
C13H13NO5
Color and Shape:
Solid
Molecular weight:
263.25
Ref: TM-T88858
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 175.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Gimatecan HCl
Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable …
Formula:
C25H26ClN3O5
Purity:
97.04%
Color and Shape:
Soild
Molecular weight:
483.94
Ref: TM-T21319L
| 1mg | 46.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 280.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Oxaquin TEA
Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that …
Formula:
C37H48F2N5O11P
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
807.77
Ref: TM-T12337L
| 1mg | 182.00 € | ||
| 5mg | 402.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,263.00 € | ||
| 100mg | 1,698.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
CH-0793076
CAS:534605-78-2
CH-0793076: hexacyclic camptothecin, TP300 metabolite, targets BCRP, inhibits DNA topo I (IC50: 2.3 μM).
Formula:
C26H26N4O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
458.51
Ref: TM-T14945
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Chimmitecan
CAS:185425-25-6
Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro …
Formula:
C23H20N2O5
Purity:
98.5%
Color and Shape:
Soild
Molecular weight:
404.42
Ref: TM-T60123
| 1mg | 90.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 283.00 € | ||
| 25mg | 436.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 858.00 € | ||
| 200mg | 1,154.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Topixantrone 2HCl
CAS:2514569-86-7
Topixantrone 2HCl is a DNA topoisomerase inhibitor with antitumor activity for the study of gastric …
Formula:
C21H28Cl2N6O2
Purity:
98.18% - 99.96%
Color and Shape:
Soild
Molecular weight:
467.39
Ref: TM-T28994L
| 1mg | 182.00 € | ||
| 5mg | 452.00 € | ||
| 10mg | 647.00 € | ||
| 25mg | 1,009.00 € | ||
| 50mg | 1,392.00 € | ||
| 100mg | 1,841.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Rebeccamycin
CAS:93908-02-2
Rebeccamycin: an antitumor antibiotic; targets DNA topoisomerase I; minor effect on kinase C and topo …
Formula:
C27H21Cl2N3O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
570.38
Ref: TM-T16726
| 500µg | 422.00 € | ||
| 2500µg | 1,878.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Pyronaridine tetraphosphate
CAS:76748-86-2
Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the …
Formula:
C29H44ClN5O18P4
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
910.03
Ref: TM-T16697
| 10mg | 35.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
