Sirtuin
Sirtuins are a family of NAD+-dependent deacetylases that play a critical role in regulating cellular processes such as DNA repair, aging, metabolism, and stress resistance. Sirtuins influence DNA repair by deacetylating proteins involved in the repair pathways, thereby modulating their activity. Sirtuin inhibitors and activators are valuable tools in research on aging, cancer, and metabolic diseases, where the regulation of DNA repair and cellular longevity is of interest. At CymitQuimica, we offer a range of high-quality sirtuin modulators to support your research in DNA repair, cellular aging, and metabolic regulation.
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SIRT-IN-5
SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation …
Ref: TM-T200735
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
SIRT1 activator 1
SIRT1 Activator 1 (Compound 3), a marine-derived xyloallenoide A derivative from the Xylaria sp.
Purity:
98%
Ref: TM-T81154
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
MDL-800
CAS:2275619-53-7
MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and …
Formula:
C21H16BrCl2FN2O6S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
626.3
Ref: TM-T64529
| 1mg | 55.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 618.00 € | ||
| 500mg | 1,290.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
ADTL-SA1215
CAS:782387-91-1
ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative …
Formula:
C26H29I2NO3
Purity:
99.23%
Color and Shape:
Liquid
Molecular weight:
657.32
Ref: TM-T40891
| 2mg | 301.00 € |
Estimated delivery in United States, on Friday 14 Feb 2025
Selisistat S-enantiomer
CAS:848193-68-0
Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) …
Formula:
C13H13ClN2O
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
248.71
Ref: TM-T7058
| 1mg | 147.00 € | ||
| 2mg | 210.00 € | ||
| 5mg | 324.00 € | ||
| 10mg | 462.00 € | ||
| 25mg | 736.00 € | ||
| 50mg | 1,049.00 € | ||
| 1mL*10mM (DMSO) | 376.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Suramin Sodium Salt
CAS:129-46-4
Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the …
Formula:
C51H34N6Na6O23S6
Purity:
97.47% - 99.97%
Color and Shape:
White
Molecular weight:
1429.15
Ref: TM-T2160
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 344.00 € | ||
| 100mg | 515.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Tenovin-3
CAS:1011301-27-1
Tenovin-3 acts as a p53 activator.
Formula:
C18H21N3OS
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
327.44
Ref: TM-T1873
| 1mg | 61.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 432.00 € | ||
| 50mg | 638.00 € | ||
| 100mg | 907.00 € | ||
| 500mg | 1,794.00 € | ||
| 1mL*10mM (DMSO) | 141.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Selisistat R-enantiomer
CAS:848193-69-1
Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer …
Formula:
C13H13ClN2O
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
248.71
Ref: TM-T15263
| 1mg | 106.00 € | ||
| 2mg | 158.00 € | ||
| 5mg | 257.00 € | ||
| 10mg | 374.00 € | ||
| 25mg | 625.00 € | ||
| 50mg | 874.00 € | ||
| 100mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 282.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Ophiopogonin D'
CAS:65604-80-0
Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 …
Formula:
C44H70O16
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
855.02
Ref: TM-TN1071
| 1mg | 117.00 € | ||
| 5mg | 295.00 € | ||
| 10mg | 438.00 € | ||
| 25mg | 703.00 € | ||
| 50mg | 960.00 € | ||
| 100mg | 1,271.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
SRT 2104
CAS:1093403-33-8
SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.
Formula:
C26H24N6O2S2
Purity:
97.03% - 99.83%
Color and Shape:
Solid
Molecular weight:
516.64
Ref: TM-T6679
| 1g | 1,613.00 € | ||
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 551.00 € | ||
| 200mg | 791.00 € | ||
| 500mg | 1,198.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
OSS_128167
CAS:887686-02-4
OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 …
Formula:
C19H14N2O6
Purity:
99.25% - 99.25%
Color and Shape:
Solid
Molecular weight:
366.32
Ref: TM-T4328
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 624.00 € | ||
| 500mg | 1,336.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
AGK7
CAS:304896-21-7
AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM …
Formula:
C23H13Cl2N3O2
Purity:
98.31%
Color and Shape:
Solid
Molecular weight:
434.27
Ref: TM-T22026
| 1mg | 70.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 201.00 € | ||
| 25mg | 423.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
SRT 2183
CAS:1001908-89-9
SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM).
Formula:
C27H24N4O2S
Purity:
97.86%
Color and Shape:
Solid
Molecular weight:
468.57
Ref: TM-T16932
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 609.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
AK-7
CAS:420831-40-9
AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models …
Formula:
C19H21BrN2O3S
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
437.35
Ref: TM-T5490
| 1mg | 36.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 529.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Fisetin
CAS:528-48-3
Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective …
Formula:
C15H10O6
Purity:
94.14% - 98.31%
Color and Shape:
Yellow To Brown Crystalline Powder
Molecular weight:
286.24
Ref: TM-T2879
| 100mg | 53.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
4'-bromo-Resveratrol
CAS:1224713-90-9
4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)
Formula:
C14H11BrO2
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
291.14
Ref: TM-T21679
| 5mg | 75.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 568.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
3-TYP
CAS:120241-79-4
3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.
Formula:
C7H6N4
Purity:
100% - 100.00%
Color and Shape:
Solid
Molecular weight:
146.15
Ref: TM-T4108
| 5mg | 56.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 256.00 € | ||
| 100mg | 460.00 € | ||
| 500mg | 1,040.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
Nicotinamide riboside chloride
CAS:23111-00-4
NR, also SRT647, is a B3 vitamin form; precursor to NAD+.
Formula:
C11H15ClN2O5
Purity:
98.92% - 99.86%
Color and Shape:
Solid
Molecular weight:
290.7
Ref: TM-T6220
| 1g | 142.00 € | ||
| 50mg | 37.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 95.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
AK-1
CAS:330461-64-8
AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.
Formula:
C19H21N3O5S
Purity:
98.32% - 99.01%
Color and Shape:
Solid
Molecular weight:
403.45
Ref: TM-T5618
| 5mg | 35.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 231.00 € | ||
| 200mg | 342.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
E1231
CAS:1031195-19-3
E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma …
Formula:
C21H21N3O3
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
363.41
Ref: TM-T9106
| 1mg | 35.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 464.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
