Sirtuin
Sirtuins are a family of NAD+-dependent deacetylases that play a critical role in regulating cellular processes such as DNA repair, aging, metabolism, and stress resistance. Sirtuins influence DNA repair by deacetylating proteins involved in the repair pathways, thereby modulating their activity. Sirtuin inhibitors and activators are valuable tools in research on aging, cancer, and metabolic diseases, where the regulation of DNA repair and cellular longevity is of interest. At CymitQuimica, we offer a range of high-quality sirtuin modulators to support your research in DNA repair, cellular aging, and metabolic regulation.
Found 91 products for "Sirtuin".
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SIRT5 inhibitor 3
CAS:SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .Formula:C22H12FN3O4Purity:98%Color and Shape:Yellow SolidMolecular weight:401.35ADTL-SA1215
CAS:ADTL-SA1215 is a SIRT3 activator with SIRT3 deacetylase activity for the study of triple negative breast cancer.Formula:C26H29I2NO3Purity:99.23%Color and Shape:SolidMolecular weight:657.32SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurity:98.80% - 98.84%Color and Shape:SolidMolecular weight:469.56Ginkgolide C
CAS:Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Formula:C20H24O11Purity:99.71% - 99.98%Color and Shape:White PowderMolecular weight:440.40Thiomyristoyl
CAS:Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.Formula:C34H51N3O3SPurity:99.16%Color and Shape:White SolidMolecular weight:581.85Ref: TM-T3447
1mg54.00€2mg73.00€5mg92.00€10mg117.00€1mL*10mM (DMSO)117.00€25mg215.00€50mg360.00€100mg537.00€E1231
CAS:E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.Formula:C21H21N3O3Purity:98.45%Color and Shape:SolidMolecular weight:363.41Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Formula:C51H34N6Na6O23S6Purity:97.47% - 99.97%Color and Shape:WhiteMolecular weight:1429.15SirReal2
CAS:SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formula:C22H20N4OS2Purity:99.52% - 99.75%Color and Shape:SolidMolecular weight:420.55Ref: TM-T6984
1mg37.00€2mg52.00€5mg74.00€1mL*10mM (DMSO)86.00€10mg102.00€25mg187.00€50mg295.00€100mg477.00€3-TYP
CAS:3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.Formula:C7H6N4Purity:99.16% - >99.99%Color and Shape:SolidMolecular weight:146.15Ref: TM-T4108
2mg37.00€5mg50.00€1mL*10mM (DMSO)50.00€10mg88.00€25mg158.00€50mg235.00€100mg371.00€200mg530.00€Nicotinamide riboside chloride
CAS:NR, also SRT647, is a B3 vitamin form; precursor to NAD+.Formula:C11H15ClN2O5Purity:98.92% - 99.95%Color and Shape:SolidMolecular weight:290.7SRT 1720 dihydrochloride
CAS:SRT 1720 dihydrochloride is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).Formula:C25H25Cl2N7OSPurity:98.58%Color and Shape:SolidMolecular weight:542.48Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Formula:C37H46O12Purity:99.06% - ≥95%Color and Shape:Yellow SolidMolecular weight:682.75Selisistat R-enantiomer
CAS:Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).Formula:C13H13ClN2OPurity:99.8%Color and Shape:White SolidMolecular weight:248.71Ref: TM-T15263
1mg101.00€2mg150.00€5mg245.00€1mL*10mM (DMSO)269.00€10mg356.00€25mg597.00€50mg835.00€100mg1,108.00€Ophiopogonin D'
CAS:Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.Formula:C44H70O16Purity:99.69% - 99.77%Color and Shape:White SolidMolecular weight:855.02Ref: TM-TN1071
1mg114.00€5mg289.00€10mg432.00€1mL*10mM (DMSO)533.00€25mg692.00€50mg945.00€100mg1,251.00€SRT1720 hydrochloride
CAS:SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM).Formula:C25H24ClN7OSPurity:98% - 99.93%Color and Shape:Yellow SolidMolecular weight:506.22Ref: TM-T2412
1mg65.00€2mg85.00€5mg132.00€1mL*10mM (DMSO)210.00€10mg236.00€25mg374.00€50mg532.00€100mg758.00€200mg1,044.00€500mg1,549.00€Selisistat
CAS:Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).Formula:C13H13ClN2OPurity:98.53% - 99.94%Color and Shape:SolidMolecular weight:248.71Ref: TM-T6111
5mg48.00€1mL*10mM (DMSO)50.00€10mg54.00€25mg87.00€50mg133.00€100mg222.00€200mg330.00€500mg535.00€AK-1
CAS:AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formula:C19H21N3O5SPurity:98.32% - 99.44%Color and Shape:SolidMolecular weight:403.45Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurity:98.89% - >99.99%Color and Shape:SolidMolecular weight:454.63Ref: TM-T1818
1mg40.00€2mg52.00€5mg73.00€1mL*10mM (DMSO)74.00€10mg93.00€25mg148.00€50mg219.00€100mg371.00€500mg882.00€UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Formula:C16H13N3Purity:98.31%Color and Shape:SolidMolecular weight:247.29Ref: TM-T7679
1mg38.00€5mg77.00€1mL*10mM (DMSO)95.00€10mg110.00€25mg215.00€50mg306.00€100mg429.00€200mg600.00€Gardenia yellow
CAS:Gardenia yellow (Crocin I) has anti atherosclerosis and hypolipidemic effects.Formula:C44H64O24Purity:98.24% - 98.82%Color and Shape:Orange Yellow To Reddish Yellow PowderMolecular weight:976.96
