Sirtuin
Sirtuins are a family of NAD+-dependent deacetylases that play a critical role in regulating cellular processes such as DNA repair, aging, metabolism, and stress resistance. Sirtuins influence DNA repair by deacetylating proteins involved in the repair pathways, thereby modulating their activity. Sirtuin inhibitors and activators are valuable tools in research on aging, cancer, and metabolic diseases, where the regulation of DNA repair and cellular longevity is of interest. At CymitQuimica, we offer a range of high-quality sirtuin modulators to support your research in DNA repair, cellular aging, and metabolic regulation.
Found 88 products of "Sirtuin"
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SRT 1460
CAS:<p>SRT 1460 is a SIRT1 activator.</p>Formula:C26H29N5O4SPurity:98.25%Color and Shape:SolidMolecular weight:507.6Cambinol
CAS:<p>Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.</p>Formula:C21H16N2O2SPurity:98.02% - 99.83%Color and Shape:SolidMolecular weight:360.43Sirtinol
CAS:<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formula:C26H22N2O2Purity:97.12% - 99.96%Color and Shape:SolidMolecular weight:394.47B2
CAS:<p>B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease</p>Formula:C20H17ClN4O3Purity:99.66%Color and Shape:SolidMolecular weight:396.83MDL-800
CAS:<p>MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.</p>Formula:C21H16BrCl2FN2O6S2Purity:99.95% - 99.96%Color and Shape:SolidMolecular weight:626.3SIRT5 inhibitor 5
CAS:<p>SIRT5 inhibitor 5 is a selective and substrate-competitive SIRT5 inhibitor, which does not occupy the NAD+ binding pocket,cancer and metabolism-related disease.</p>Formula:C21H14ClN3O3SPurity:99.33%Color and Shape:SolidMolecular weight:423.87SIRT5 inhibitor 2
CAS:<p>SIRT5 inhibitor 2 (compound 49) has inhibitory activity through SIRT5-dependent deacetylation and cancer and neurodegenerative diseases.</p>Formula:C18H12Cl2N2O3SPurity:99.38% - 99.87%Color and Shape:SolidMolecular weight:407.27SIRT2-IN-9
CAS:<p>SIRT2-IN-9: selective SIRT2 inhibitor; IC50=1.3μM; halts MCF-7 cell growth; for cancer study.</p>Formula:C21H22N6OS2Purity:99.5%Color and Shape:SolidMolecular weight:438.57SIRT5 inhibitor 6
CAS:<p>SIRT5 inhibitor 6 is Sirtuin 5 inhibitor for sepsis-associated acute kidney injury (AKI) modulates protein succinylation and pro-inflammatory cytokine release.</p>Formula:C21H28N6O4SPurity:99.84%Color and Shape:SolidMolecular weight:460.55Sirt2-IN-1
CAS:<p>Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).</p>Formula:C28H27N7O2S2Purity:99.57% - 99.84%Color and Shape:SolidMolecular weight:557.69SIRT5 inhibitor 4
CAS:<p>SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitorand no inhibitory effect on SIRT1/2/3,anticancer.</p>Formula:C18H15N3O4SPurity:99.97%Color and Shape:SolidMolecular weight:369.39SIRT5 inhibitor 1
CAS:<p>SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked to aging diseases.</p>Formula:C31H39FN6O6S2Purity:97.8%Color and Shape:SolidMolecular weight:674.81SIRT6-IN-5
CAS:<p>SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, curbs T-cell growth.</p>Formula:C19H14N2O6Purity:98.77%Color and Shape:SolidMolecular weight:366.32Sirtuin modulator 1
CAS:<p>Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.</p>Formula:C31H32ClN5O2S2Purity:99.63%Color and Shape:SolidMolecular weight:606.2WAY-354574
CAS:<p>WAY-354574 is an active compound that targets the deacetylase Sirtuin, utilized in research focused on Huntington's disease (HD) [1].</p>Formula:C20H23ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:406.93Sirtuin-1 inhibitor 1
CAS:<p>Sirtuin-1 inhibitor 1 is an inhibitor against deacetylase-1 (Sirtuin-1) and can be used to study senescence and cell death in the organism.</p>Formula:C20H17N3O2Purity:99.1%Color and Shape:SolidMolecular weight:331.37Epigenetic factor-IN-1
CAS:<p>Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.</p>Formula:C32H34FN5O6S2Purity:98%Color and Shape:SolidMolecular weight:667.77SRT3657
CAS:<p>SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.</p>Formula:C40H54N8O6SPurity:98%Color and Shape:SolidMolecular weight:774.97SIRT5 inhibitor 7
CAS:<p>SIRT5 inhibitor 7 , a substrate-competitive and selective SIRT5 inhibitor, significantly attenuated renal dysfunction and pathological damage in AKI mice.</p>Formula:C28H32ClN7O3SPurity:99.77%Color and Shape:SolidMolecular weight:582.12SIRT-IN-1
CAS:<p>SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).</p>Formula:C19H27N5O2SPurity:99.29%Color and Shape:SolidMolecular weight:389.52
