Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(229 products)
- Annexin A(16 products)
- Aromatase(23 products)
- Estrogen/progestogen Receptor(66 products)
- GPR(1 products)
- Glucocorticoid Receptor(165 products)
- LHRH(2 products)
- Opioid Receptor(327 products)
- Prostaglandin Receptor(122 products)
- RAAS(89 products)
- Reductase(51 products)
- Somatostatin(57 products)
- Thyroid hormone receptor(THR)(33 products)
- Vasopressin Receptor(48 products)
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Found 3420 products of "Endocrinology/Hormones"
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Trioxifene mesylate
CAS:Trioxifene mesylate is an antiestrogen that suppresses growth hormone secretion.Formula:C31H35NO6SPurity:98%Color and Shape:SolidMolecular weight:549.68Mitolactol
CAS:Mitolactol: an alkylating agent used in breast cancer and brain tumors; marrow-toxic; may combine with other drugs.Formula:C6H12Br2O4Purity:98%Color and Shape:SolidMolecular weight:307.96rac Salsolinol, Hydrobromide
CAS:rac Salsolinol, Hydrobromide is a useful organic compound for research related to life sciences. The catalog number is T124585 and the CAS number is 59709-57-8.Formula:C10H14BrNO2Color and Shape:SolidMolecular weight:260.128TCF199
TCF199, a conformational stabilizer, facilitates the interaction between the 14-3-3ζ/E R α peptide and the 14-3-3ζ/Chibby peptide, thereby stabilizing the 14-3-3/TAZ peptide complex. The dissociation constant (Kd) of TCF199 with the 14-3-3/TAZ complex is 122 μM.Formula:C17H24N2O2Color and Shape:SolidMolecular weight:288.38OT antagonist 3 analog
OT antagonist 3 analog is an analog of OT antagonist 3.Formula:C20H18N6O2Purity:98%Color and Shape:SolidMolecular weight:374.4A 65317
CAS:A 65317 is a selective renin inhibitor that causes a blockade of the renin-angiotensin system.Formula:C38H58N6O9Color and Shape:SolidMolecular weight:742.90THR-β agonist 8
CAS:THR-β agonist 8 (Compound 1) is an orally active agonist for both TRα and TRβ. It holds potential for research into thyroid hormone-related diseases.Formula:C19H12Cl2N4O4Color and Shape:SolidMolecular weight:431.23NR-V04
CAS:NR-V04 is a PROTAC degrader targeting NR4A1.Formula:C62H87N5O11SColor and Shape:SolidMolecular weight:1110.45CJ-15208
CAS:CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).
Formula:C34H35N5O4Color and Shape:SolidMolecular weight:577.67Flucloronide
CAS:Flucloronide is a corticosteroid for topical use on the skin. It has anti-inflammatory properties.Formula:C24H29Cl2FO5Color and Shape:SolidMolecular weight:487.39Chlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formula:C7H6ClN3O4S2Purity:98.46% - 98.91%Color and Shape:Crystals Physical Description Crystals; White Powder (Ntp 1992)Molecular weight:295.72Dexamethasone cipecilate
CAS:Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid.Formula:C33H43FO7Purity:98%Color and Shape:SolidMolecular weight:570.69Teriparatide
CAS:Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).Formula:C181H291N55O51S2Purity:98%Color and Shape:SolidMolecular weight:4117.72Diisononyl phthalate
CAS:Diisononyl phthalate (DINP), a phthalate, a plasticizer, activates the ACE/AT1R axis and inhibits NO production, inducing elevated blood pressure in mice.Formula:C26H42O4Purity:99.97%Color and Shape:Colorless Liquid In Water (Uscg 1999)Molecular weight:418.61Prednisolone farnesylate
CAS:Prednisolone farnesylate is a novel transdermal corticosteroid with anti-inflammatory activity.
Formula:C36H50O6Purity:98%Color and Shape:SolidMolecular weight:578.78[Arg8]-Vasotocin
CAS:[Arg8]-Vasotocin is a hormone present in the neurohypophysis of nonmammalian vertebrates that is related to vasopressin and oxytocin.Formula:C43H67N15O12S2Purity:98%Color and Shape:SolidMolecular weight:1050.22Commendamide
CAS:Commendamide, natural, mimics N-acyl-amides, activates GPR132 with EC50 of 11.8 μM, made by Cbeg12 gene in commensal bacteria.Formula:C18H35NO4Color and Shape:SolidMolecular weight:329.47SR 43845
CAS:SR 43845 is an inhibitor of renin.Formula:C44H64N8O8Purity:98%Color and Shape:SolidMolecular weight:833.044SRD5A1-IN-1
CAS:SRD5A1-IN-1 inhibits SRD5A1 with IC50 of 1.44µM, reducing dihydrotestosterone and SRD5A1 expression.Formula:C17H11F6NO3Purity:99.67% - 99.74%Color and Shape:SoildMolecular weight:391.27Ref: TM-T67901
1mg60.00€5mg133.00€1mL*10mM (DMSO)147.00€10mg187.00€25mg304.00€50mg420.00€100mg532.00€200mg705.00€Ludaterone
CAS:Ludaterone is an antiandrogen agent, with potent antiandrogenic activity.Formula:C20H25ClO5Color and Shape:SolidMolecular weight:380.86Calcitonin, eel
CAS:Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.
Formula:C146H241N43O47S2Purity:98%Color and Shape:White PowderMolecular weight:3414.91RG 13647
CAS:RG 13647 is an agonist of angiotensin II peptide.Formula:C30H27N3O5Purity:98%Color and Shape:SolidMolecular weight:509.552-PCCA hydrochloride
CAS:2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with anFormula:C30H39Cl2N3OPurity:97.54% - 99.07%Color and Shape:SoildMolecular weight:528.56Ref: TM-T80666
1mg86.00€5mg183.00€1mL*10mM (DMSO)215.00€10mg259.00€25mg416.00€50mg550.00€100mg752.00€200mg1,008.00€rac-1,2-bis-Palmitoyl-3-chloropropanediol
CAS:3-MCPD ester found in edible oils, highest in olive pomace; toxic to mouse kidneys and spermatids.Formula:C35H67ClO4Color and Shape:SolidMolecular weight:587.37N-terminally acetylated Endomorphin-1
N-terminally acetylated Endomorphin-1 is a modified Endomorphin-1.Formula:C36H40N6O6Purity:98%Color and Shape:SolidMolecular weight:652.74N-Acetyl-α-Endorphin
CAS:N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal.Formula:C79H122N18O27SPurity:98%Color and Shape:SolidMolecular weight:1787.98Valorphin
CAS:Valorphin (Valorphin TFAsalt) has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM.Formula:C44H61N9O11Purity:98%Color and Shape:SolidMolecular weight:892.01Oxytocin free acid
CAS:Oxytocin analog with glycine at position 9; impacts health, development, reproduction, behavior.Formula:C43H65N11O13S2Color and Shape:SolidMolecular weight:1008.18Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formula:C90H120N22O16SColor and Shape:SolidMolecular weight:1798.15DPI-287
CAS:DPI-287, a selective delta-opioid receptor (DOP) agonist, has a K\(_i\) value of 0.39 nM and is applicable for pain research [1].Formula:C31H39N3O2Molecular weight:485.66Hodgkinsine
CAS:Hodgkinsine, a pyrrolidinoindoline alkaloid with analgesic properties, found in P. colorata, increases pain tolerance in mice at 5 mg/kg.Formula:C33H38N6Color and Shape:SolidMolecular weight:518.70Opioid receptor agonist 1
Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.Formula:C32H45N5OColor and Shape:SolidMolecular weight:515.73ER ligand-8
CAS:ER ligand-8 is a ligand of the estrogen receptor (Estrogen Receptor/ERR) and can be used for the synthesis of the PROTAC molecule ERD-1233.Formula:C30H27F9O4SColor and Shape:SolidMolecular weight:654.5846β-hydroxy Dexamethasone
CAS:6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.Formula:C22H29FO6Color and Shape:SolidMolecular weight:408.46Dynorphin A (1-13) amide
CAS:Dynorphin A (1-13) amide, an endogenous opioid peptide, counteracts the analgesic effects of morphine [1].Formula:C75H127N25O14Molecular weight:1602.97Raloxifene dimethyl ester hydrochloride
CAS:Raloxifene dimethyl ester hydrochloride is an analog of Raloxifene.Formula:C32H32ClNO6SColor and Shape:SolidMolecular weight:594.12Hodgkinsine B
CAS:Hodgkinsine B, a pain-relieving alkaloid, increases tail-flick latency in mice at 10 mg/kg dose.Formula:C33H38N6Color and Shape:SolidMolecular weight:518.70Cortodoxone-d7
Cortodoxone-d7 (11-Deoxycortisol-d7) is a deuterium-labeled form of Cortodoxone. Cortodoxone (11-Deoxycortisol; cortexolone) is both a glucocorticoid steroid hormone and a glucocorticoid antagonist. It enhances tryptophan oxygenase (TO) activity and stimulates the secretion of corticosterone. Additionally, Cortodoxone regulates the proliferation and activation of T cells.Formula:C21H23D7O4Color and Shape:SolidMolecular weight:353.501,4-Dihydropyridine
1,4-Dihydropyridine acts as an antagonist for calcium channels (calcium channel), specifically blocking the L-type calcium channels. This action reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, consequently decreasing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure.Formula:C12H17NO4Color and Shape:SolidMolecular weight:239.27pTH-Related Protein (1-34) amide (human, mouse, rat)
CAS:Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP.Color and Shape:Solid17,17-(Ethylenedioxy)androst-4-en-3-one
CAS:17,17-(Ethylenedioxy)androst-4-en-3-one, used in cosmetics for acne and hair growth, inhibits reductase and 5α-DHT receptor binding.Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46ALR2-IN-1
CAS:ALR2-IN-1: potent, selective inhibitor of ALR2 (IC50=1.42 μM), antiglycemic, antioxidant; for diabetes research.Formula:C16H17N3O2SPurity:99.41%Color and Shape:SoildMolecular weight:315.3921-hydroxy Eplerenone
CAS:21-hydroxy Eplerenone, a key eplerenone metabolite, is produced via CYP3A4.Formula:C24H30O7Color and Shape:SolidMolecular weight:430.497ER ligand-9
CAS:ER ligand-9 is a conjugate of an estrogen receptor (Estrogen Receptor/ERR) ligand and a linker, utilized in the synthesis of PROTACs ERD-1233.Formula:C31H33NO3Color and Shape:SolidMolecular weight:467.599[Glu4]-Oxytocin
CAS:'[Glu4]-Oxytocin is a variant for studying 'oxytocin-like' molecule shapes in water.'Formula:C43H65N11O13S2Molecular weight:1008.1815-keto Prostaglandin A1
CAS:PGA1, derived from PGE1 in semen, creates 15-keto PGA1 via dehydrogenase, inducing vasoconstriction at 6μM like angiotensin II.Formula:C20H30O4Color and Shape:SolidMolecular weight:334.45Nurr1 agonist 6
Compound 13, a Nurr1 agonist, exhibits a dissociation constant (Kd) of 1.5 μM and an effective concentration for 50% response (EC50) of 3 μM [1].Color and Shape:Odour Solidα-Neoendorphin (1-8)
CAS:α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin.Formula:C49H70N12O11Purity:98%Color and Shape:SolidMolecular weight:1003.153,5-Diiodothyroacetic Acid
CAS:3,5-Diiodothyroacetic acid is a thyroid hormone analog that has been found to reduce cholesterol concentrations and may be used in the study of hypothyroidism.Formula:C14H10I2O4Color and Shape:SolidMolecular weight:496.0397-FluorotryptaMine HCl
CAS:7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used toFormula:C10H12ClFN2Purity:98.06%Color and Shape:SolidMolecular weight:214.67Dimestrol
CAS:Dimestrol can induce DNA damage.Formula:C20H24O2Color and Shape:SolidMolecular weight:296.4Dafphedyn
CAS:Dafphedyn (DAFPHEDYN), a potent endorphin 1-13 analog, induces diuresis and analgesia in rats via IV.Formula:C76H124F5N25O14Color and Shape:SolidMolecular weight:1706.95Oxytocin parallel dimer
CAS:Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer.Formula:C86H132N24O24S4Color and Shape:SolidMolecular weight:2014.39Fluticasone 17β-Carboxylic Acid
CAS:Fluticasone 17β-carboxylic acid is an intermediate in the synthesis of the glucocorticosteroid fluticasone propionate .1Formula:C21H26F2O5Color and Shape:SolidMolecular weight:396.42(-)-Vorozole
CAS:(-)-Vorozole, potent/selective oral non-steroidal aromatase inhibitor, shows antitumor activity, used in breast cancer research.Formula:C16H13ClN6Purity:99.02% - >99.99%Color and Shape:SoildMolecular weight:324.77(±)-ErSO
CAS:(±)-ErSO is the racemic form of ErSO. ErSO is a selective anticipatory activator of the unfolded protein response (a-UPR).Formula:C22H13F6NO3Color and Shape:SolidMolecular weight:453.3417β-hydroxy Exemestane
CAS:17β-hydroxy Exemestane is the primary active metabolite of exemestane .Formula:C20H26O2Color and Shape:SolidMolecular weight:298.425-methyl-2-HOBA (hydrochloride)
CAS:5-methyl-2-HOBA is an isoketal scavenger. It reduces angiotensin II-induced increases in systolic blood pressure in mice.Formula:C8H12ClNOColor and Shape:SolidMolecular weight:173.64Lodoxamide ethyl
CAS:lodoxamide ethyl is a new orally active anti-allergic compound for the prevention of antigen-induced bronchoconstriction and blockage of skin allergic reactionsFormula:C15H14ClN3O6Purity:99.56%Color and Shape:SolidMolecular weight:367.74[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
CAS:Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo.Formula:C61H102N22O14Purity:98%Color and Shape:SolidMolecular weight:1367.6ER ligand-6
CAS:ER ligand-6 serves as the target protein ligand for the PROTAC ER Degrader-14.
Formula:C29H32FNO4Color and Shape:SolidMolecular weight:477.567ER ligand-7
ER ligand-7 is a ligand for the estrogen receptor (ER) that can be used as a target protein ligand for synthesizing PROTAC ER Degrader-15.
Formula:C27H23F4NO3Color and Shape:SolidMolecular weight:485.47Tamoxifen-PEG-Clozapine
Tamoxifen-PEG-Clozapine is an estrogen receptor α (ERα) PROTAC degrader. It targets ERα for degradation through the ubiquitin-proteasome system by utilizing the E3 ubiquitin ligase component N-recognin 5. This compound is applicable in cancer research. (Pink: ERα inhibitor; Black: linker; Blue: CRBN Ligand)Formula:C54H63ClN6O7Color and Shape:SolidMolecular weight:943.567AR ligand-33
AR ligand-33 is a ligand for the androgen receptor (AR), and it can be used as a target protein ligand for the synthesis of PROTAC AR Degrader-8.Formula:C25H28N2O3Color and Shape:SolidMolecular weight:404.501RU26988
CAS:RU26988 is a bioactive chemical.Formula:C22H26O3Color and Shape:SolidMolecular weight:338.44Paramethasone
CAS:Parametasone is a glucocorticoid with the general properties of corticosteroids.Formula:C22H29FO5Color and Shape:SolidMolecular weight:392.46Human PTHrP-(1-36)
CAS:Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFormula:C191H305N59O52Color and Shape:SolidMolecular weight:4259.83Demoxytocin
CAS:Demoxytocin, oxytocin analog, enhances smooth muscle contraction by increasing calcium ion permeability. Used in labor research.Formula:C43H65N11O12S2Color and Shape:SolidMolecular weight:992.17PROTAC ER Degrader-12
PROTACER Degrader-12 (Compound 70) is an estrogen receptor PROTAC degrader with a degradation concentration (DC50) of less than 10 nM. It inhibits the proliferation of MCF-7 cells at a DC50 of under 10 nM and exhibits anticancer properties.Formula:C47H48F3N5O5Molecular weight:819.36075Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formula:C42H55F3N8O10Purity:98%Color and Shape:SolidMolecular weight:888.93β-S-ARCA triammonium
β-S-ARCA (triammonium) is an analog of the mRNA7-methylguanosine (m7G) cap structure, featuring a thio-phosphorylated segment. When bound to mRNA, β-S-ARCA (triammonium) extends the cellular half-life and enhances protein expression. This compound is utilized in research for mRNA-based cancer vaccines.Formula:C22H40N13O17P3SColor and Shape:SolidMolecular weight:883.62K-Opioid receptor agonist-1
CAS:K-Opioid receptor agonist-1 (Compound 5a) acts as an agonist for the κ-Opioid receptor, exhibiting a K_i of 0.25 nM and an EC_50 of 2 nM. This compound is capable of crossing the blood-brain barrier (BBB), evidenced by brain/plasma ratios ranging from 0.50 to 0.65. Additionally, K-Opioid receptor agonist-1 demonstrates anti-inflammatory effects in dermatitis models induced by either Arachidonic acid or oxazolidinone.Formula:C22H29Cl2N3O3Molecular weight:454.39Bilaid C
CAS:Bilaid C: Tetrapeptide μ-opioid agonist from Penicillium (Ki=210 nM), inhibits cAMP (77% at 10 μM), induces Kir currents (EC50=4.2 μM).Formula:C28H38N4O6Molecular weight:526.62D-Ala-Gly-Phe-Met-NH2 monoacetate
CAS:D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, serves as a potent agonist for the opiate δ-receptor [1].Formula:C21H33N5O6SColor and Shape:SolidMolecular weight:483.58PROTAC AR Degrader-10
PROTACAR Degrader-10 is a protein degrader targeting androgen receptors (AR) with a DC50 value of ≤100 nM, and can be used in prostate cancer research.6-Amino-5-bromoquinoxaline
CAS:Compound PDK0245, with CAS No. 50358-63-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0245 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C8H6BrN3Color and Shape:Yellow SolidMolecular weight:224.05[D-Ala2]-Met-Enkephalinamide
CAS:[D-Ala2]-Met-Enkephalinamide: potent opioid, reduces bile flow centrally, analgesic.Formula:C28H38N6O6SMolecular weight:586.7Trh-gly
CAS:TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Formula:C18H24N6O6Color and Shape:SolidMolecular weight:420.42ACTH (6-24) (human)
CAS:Adrenocorticotropic hormone (6-24) (ACTH (6-24) (human)) is a fragment of ACTH that acts as a competitive inhibitor of steroidogenesis prompted by full-lengthFormula:C111H175N35O21Color and Shape:SolidMolecular weight:2335.8Enkephalin-met, ala(2)-
CAS:Enkephalin-met, ala(2)- is a synthetic analog of methionine enkephalin.Formula:C28H37N5O7SColor and Shape:SolidMolecular weight:587.69Human PTH-(1-31) amide
CAS:Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Formula:C162H270N50O46S2Color and Shape:SolidMolecular weight:3718.31MOR agonist-4
MOR agonist-4 (2d), having an EC50 of 11 nM, is a G protein-biased agonist of the Kappa opioid receptor (KOR). This compound features a triazole-based, electron-withdrawing CF3 group and a bias factor of 38. MOR agonist-4 is utilized for antipruritic and analgesic applications.Color and Shape:Odour SolidArg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Formula:C129H179N37O24SMolecular weight:2662.36444Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS:Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFormula:C27H42N10O7Molecular weight:618.69Kisspeptin-14 human
CAS:Kisspeptin-14 human is an active fragment peptide of Kisspeptin encoded by the KiSS-1 gene. Kisspeptin-14 human is a GPR54 agonist for human and rat.Formula:C82H112N22O21Color and Shape:SolidMolecular weight:1741.9Acetalin-2
CAS:Acetalin-2, an opioid peptide with the sequence Ac-Arg-Phe-Met-Trp-Met-Arg-NH2, selectively binds to [3 H]DAMGO with a Ki value of 93.3 nM [1].Formula:C44H66N14O7S2Molecular weight:967.21Antiproliferative agent-51
Antiproliferative agent-51 (Compound 18h) inhibits estrogen receptor α (ERα)-mediated transcription with an IC50 of 1.6 nM. It also suppresses the proliferation of cancer cells ZR-75, with an IC50 of 0.031 μM, and exhibits antitumor activity in mouse models.Formula:C43H50N4O9Molecular weight:766.35778Chymase
CAS:Chymase is a proteolytic enzyme predominantly found in mast cells (MC), fibroblasts, and vascular endothelial cells. It is released into the extracellular matrix in response to inflammatory signals, tissue damage, and cellular stress. Chymase also plays a role in the generation of angiotensin II (Ang II), making it significant for cardiovascular disease research.Termitomycamide B
CAS:Termitomycamide B, a fatty acid from T. titanicus, protects Neuro2a cells from ER stress-induced death at 0.1 μg/ml.Formula:C28H40N2O2Color and Shape:SolidMolecular weight:436.63β-Chlornaltrexamine dihydrochloride
CAS:β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is an effective long-term antagonist of opioid receptors. It efficiently blocks the inhibition of dopamine release mediated by κ opioid receptor agonists. This compound is useful in the research of pain perception mechanisms.Formula:C24H34Cl4N2O3Color and Shape:SolidMolecular weight:540.35Ota-vasotocin
CAS:Ota-vasotocin is a ligand utilized in quantitative receptor autoradiography for oxytocin receptors.Formula:C54H79N11O13S2Molecular weight:1154.41TRV055
CAS:TRV055: Gq-biased AT1R ligand, stimulates Gq signaling, aids Gq-biased agonist development.Formula:C42H57N9O9Color and Shape:SolidMolecular weight:831.972[Asp5]-Oxytocin
CAS:[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity.Formula:C43H65N11O13S2Molecular weight:1008.18Morphiceptin
CAS:Morphiceptin is a synthetic tetrapeptide with morphinelike activities, highly specific for morphine receptors, but not for enkephalin receptors.Formula:C28H35N5O5Molecular weight:521.61Detrothyronine
CAS:Detrothyronine is a biochemical.Formula:C15H12I3NO4Color and Shape:SolidMolecular weight:650.97Biotin-Oxytocin
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biologically active peptide. It is oxytocin labeled with biotin at the N-terminus.Formula:C53H80N14O14S3Molecular weight:1232.51406[Asp5]-Oxytocin acetate
[Asp5]-Oxytocin acetate: a biologically active neurohypophyseal hormone analogue, inducing uterine contractions, effects magnified by Mg2+.Formula:C45H69N11O15S2Molecular weight:1068.22BPRMU191
CAS:BPRMU191 is a distinct mu-opioid receptor (MOR) modulator with an EC50 of 2.17 μM in FLIPR Ca2+ assays conducted on CHO-K1/MOR/Gα15 cells. Additionally, BPRMU191 interacts with MOR in the presence of naloxone.Formula:C17H14FNO3SColor and Shape:SolidMolecular weight:331.36Saprisartan
CAS:Saprisartan (GR-138950, GR-138950X) is an AT1 receptor antagonist used for the treatment of heart failure and blood pressure.Formula:C25H22BrF3N4O4SColor and Shape:SolidMolecular weight:611.43Keap1-IN-1
Keap1-IN-1 (Compound 27) is an inhibitor of Keap1, functioning by covalently modifying the Cys151 residue on the BTB domain of KEAP1, thereby disrupting the interaction between Keap and Nrf. It enhances the mRNA expression of the antioxidant response element (ARE) dependent gene NQO1, with an EC50 of 160 nM, and exhibits cytotoxicity in U2OS cells, with an EC50 of 527 nM.Formula:C17H21Cl2N2O5PS3Color and Shape:SolidMolecular weight:531.434
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