Endocrinology/Hormones

CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.

<p>Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin), is a naturally occurring, endogenous opioid peptide that inhibits tumor growth via binding to the opioid receptor.</p>

Deltorphin 2 ([D-Ala2]-Deltorphin II) is an agonist of δ opioid receptor with an IC50 of 1 nM.

4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency.

[Leu5]-Enkephalin TFA(58822-25-6(free bas)) (Leucyl-enkephalin) is the most potent δ-receptor ago

Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.

Losartan Carboxylic Acid (E-3174) is a potent AT1 blocker with vasodilatory effects, stronger than losartan, with Kis of 0.57 nM in rats and 0.67 nM in humans.

PPT is a selective ERα agonist with 410x higher affinity than for ERβ.

Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TIMP1, and the Human TIMP1 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human TIMP1. After TMB substrate solution is added, only those wells that contain Human TIMP1 and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TIMP1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) has anti-inflammatory activity and may be used in the study of rheumatoid arthritis.

<p>Ethaselen (BBSKE) is an oral TrxR inhibitor with IC50 of 0.5 μM (human) and 0.35 μM (rat), targeting a selenocysteine site to fight NSCLC.</p>

Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).

This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human PG antigen, and the Human PG standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human PG to each microplate well and incubated . After TMB substrate solution is added, the enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ±10nm. The concentration of Human PG in the samples is then determined by comparing the OD of the samples to the standard curve.

Estradiol 3-sulfamate (BLE 00084) is an ES inhibitor with a K(i) value of 73 nM for ES in human placental microsomes and is used in breast cancer research.

Methyl candesartan (Candesartan Methyl Ester) 是一种有效的血管紧张素2受体拮抗剂，可用于研究高血压。

<p>NCRW0005-F05 is a potent agonist of orphan G-protein coupled receptor GPR139 with an IC 50 value of 0.21 μM.</p>

This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human fT3 antigen, and the Human fT3 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human fT3 to each microplate well and incubated . After TMB substrate solution is added, the enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ±10nm. The concentration of Human fT3 in the samples is then determined by comparing the OD of the samples to the standard curve.

Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.

This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Rat E2 antigen, and the Rat E2 standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Rat E2 to each microplate well and incubated . After TMB substrate solution is added, the enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ±10nm. The concentration of Rat E2 in the samples is then determined by comparing the OD of the samples to the standard curve.