Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(207 products)
- Annexin A(11 products)
- Aromatase(20 products)
- Estrogen/progestogen Receptor(49 products)
- GPR(1 products)
- Glucocorticoid Receptor(153 products)
- LHRH(1 products)
- Opioid Receptor(296 products)
- Prostaglandin Receptor(119 products)
- RAAS(86 products)
- Reductase(52 products)
- Somatostatin(46 products)
- Thyroid hormone receptor(THR)(26 products)
- Vasopressin Receptor(44 products)
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Found 3178 products of "Endocrinology/Hormones"
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PROTAC ER Degrader-2
<p>PAC, based on WO2017201449A1's LP2, enhances ERα degradation; used in making ADCs with PROTAC-linker, it's attached to antibodies.</p>Formula:C89H104N12O15Purity:98%Color and Shape:SolidMolecular weight:1581.854',2-Dihydroxy-4,6-dimethoxydihydrochalcone
CAS:<p>4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen-like compound, binds to bovine estrogen receptors, IC50 15 μM.</p>Formula:C17H18O5Color and Shape:SolidMolecular weight:302.3214-3-3σ/ERα stabilizer-1
<p>Compound 181, also known as 14-3-3σ/ERα Stabilizer-1, is a covalent stabilizer targeting the 14-3-3σ/ERα proteins.</p>Formula:C25H35Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:496.47D3R/MOR antagonist 1
<p>Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM</p>Formula:C22H27Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:420.38CTAP
CAS:<p>Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.</p>Formula:C51H69N13O11S2Purity:98%Color and Shape:White Solid/PowderMolecular weight:1104.32TAN67
CAS:<p>TAN67 is the first effective selective non-peptide delta1 opioid receptor.</p>Formula:C23H26Br2N2OColor and Shape:SolidMolecular weight:506.282Urotensin II, mouse TFA (9047-55-6 free base)
<p>Urotensin II, mouse TFA is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.</p>Formula:C78H101N18F3O21S2Purity:98%Color and Shape:SolidMolecular weight:1747.88OT antagonist 1 demethyl derivative
<p>OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 is a selective Oxytocin antagonist (Ki of 50 nM. )</p>Formula:C21H20N4O3Purity:98%Color and Shape:SolidMolecular weight:376.41SR 43845
CAS:<p>SR 43845 is an inhibitor of renin.</p>Formula:C44H64N8O8Purity:98%Color and Shape:SolidMolecular weight:833.044DPP-4/GPR119 modulator 1
CAS:<p>Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.</p>Formula:C30H39ClN10O3Color and Shape:SolidMolecular weight:623.15Vasopressin Dimer (anti-parallel) (TFA)
<p>Vasopressin Dimer (anti-parallel) TFA, an anti-parallel dimer form of vasopressin, has the capability to activate four G protein-coupled receptors: V1aR, V1bR,</p>Formula:C94H131F3N30O26S4Purity:98%Color and Shape:SolidMolecular weight:2282.49β-Endorphin, equine
CAS:<p>Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.</p>Formula:C154H248N42O44SPurity:98%Color and Shape:SolidMolecular weight:3423.94N-Phenethylnoroxymorphone
CAS:<p>N-Phenethylnoroxymorphone is an opioid compound that can enhance morphine-induced analgesia in rats. It is used in the research of neurological disorders.</p>Formula:C24H25NO4Color and Shape:SolidMolecular weight:391.46β-Endorphin, equine TFA
<p>β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3</p>Formula:C156H249F3N42O46SColor and Shape:SolidMolecular weight:3537.96Adrenorphin
CAS:<p>Adrenorphin (Metorphamide)(3TFA) is an agonist of μ-opioid receptor(Ki :12 nM).</p>Formula:C44H69N15O9SPurity:98%Color and Shape:SolidMolecular weight:984.182-PCCA hydrochloride
CAS:<p>2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an</p>Formula:C30H39Cl2N3OPurity:97.54% - 99.36%Color and Shape:SoildMolecular weight:528.56(S,S)-J-113397
CAS:<p>(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .</p>Formula:C24H37N3O2Color and Shape:SolidMolecular weight:399.57WCA-814
<p>WCA-814, an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate, induces degradation of both full-length and AR-V7, exhibiting cytotoxic effects in</p>Formula:C46H53ClN10O5Purity:98%Color and Shape:SolidMolecular weight:861.43OT-R antagonist 1
CAS:<p>OT-R antagonist 1: Nonpeptide, selective, low-weight blocker of oxytocin; IC50 = 8 nM for Ca2+ disruption.</p>Formula:C28H29N3O4Purity:98%Color and Shape:SolidMolecular weight:471.55Montirelin
CAS:<p>Montirelin is an analog of thyrotropin-releasing hormone.</p>Formula:C17H24N6O4SColor and Shape:SolidMolecular weight:408.48D3R/MOR antagonist 2
<p>Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MOR</p>Formula:C25H31ClN2OPurity:98%Color and Shape:SolidMolecular weight:410.9815,26-Dihydroxylanosta-7,9(11),24-trien-3-one
CAS:<p>15,26-Dihydroxylanosta-7,9(11),24-trien-3-one is a natural product that can be used as a reference standard. The CAS number of 15,26-Dihydroxylanosta-7,9(11),24-trien-3-one is 420781-85-7.</p>Formula:C30H46O3Color and Shape:SolidMolecular weight:454.7ET receptor antagonist 3
<p>"ET receptor antagonist 3 (compound 17d) is an orally active ET receptor antagonist with an IC50 of 0.26 nM, utilized for pulmonary arterial hypertension (PAH)</p>Formula:C27H28N6O5SPurity:98%Color and Shape:SolidMolecular weight:548.61Alclometasone
CAS:<p>Alclometasone is a glucocorticoid that reduces inflammation and treats various skin conditions like eczema and psoriasis.</p>Formula:C22H29ClO5Purity:98%Color and Shape:SolidMolecular weight:408.92Methylprednisolone Acetate
<p>Methylprednisolone Acetate(Depo-Medrate) has the ability to inhibit oxygen free radicals and can be used to treat acute spinal cord injuries.</p>Formula:C24H32O6Purity:99.74%Color and Shape:Off-White SolidMolecular weight:416.51ARD-2051
CAS:<p>ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading AR</p>Formula:C43H45ClN8O5Purity:98%Color and Shape:SolidMolecular weight:789.32AM-5262
CAS:<p>AM-5262 is a potent GPR40 Full Agonist with improved rat PK profile and general selectivity profile.</p>Formula:C33H35FO4Color and Shape:SolidMolecular weight:514.63(1S,2R)-2-PCCA
<p>(1S,2R)-2-PCCA is a novel and potent small molecule GPR88 receptor agonist with an EC50 value of 3 nM in the non-cellular system and 603 nM in the cellular</p>Formula:C30H39Cl2N3OPurity:99.41%Color and Shape:SoildMolecular weight:528.56Nurr1 agonist 2
CAS:<p>Nurr1 agonist 2 with EC50 of 0.07 μM, boosts TH & VMAT2 mRNA, binds Nurr1 LBD at Kd 0.14 μM, for parkinsonism study.</p>Formula:C18H14O3SPurity:98.78%Color and Shape:SoildMolecular weight:310.37Eprosartan
CAS:<p>Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.</p>Formula:C23H24N2O4SPurity:>99.99%Color and Shape:SolidMolecular weight:424.51Dynorphin B (1-13)
CAS:<p>Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.</p>Formula:C74H115N21O17Purity:98%Color and Shape:SolidMolecular weight:1570.84TrxR1 prodrug-1
<p>TrxR1 prodrug-1 (compound 5u) is a potent inhibitor of TrxR1, demonstrating significant antitumor activity in nude mice and NSCLC organoids.</p>Formula:C22H30N2O6S2Color and Shape:SolidMolecular weight:482.613DPDPE
CAS:<p>DPDPE is selective δ-opioid receptor agonist peptide.</p>Formula:C30H39N5O7S2Purity:98%Color and Shape:SolidMolecular weight:645.79Dermorphin Analog
<p>Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.</p>Formula:C44H59N11O10Purity:98%Color and Shape:SolidMolecular weight:901.43AZ'6421
CAS:<p>"AZ'6421: A PROTAC degrading estrogen receptor alpha; potent in anti-tumor activity, useful for cancer research."</p>Formula:C52H65F3N6O7SColor and Shape:SolidMolecular weight:975.17Yp537
CAS:<p>Yp537 acts as an estrogen receptor (ER) inhibitor, specifically preventing the dimerization of the human estrogen receptor [1].</p>Formula:C64H104N13O22PSColor and Shape:SolidMolecular weight:1470.62PF-06478939
<p>PF-06478939 is a peptide that functions as an agonist at the oxytocin (OT) receptor and vasopressin receptor without crossing the blood-brain barrier.</p>Formula:C78H134N14O22S2Purity:98%Color and Shape:SolidMolecular weight:1684.11[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Formula:C61H99FN22O15Purity:98%Color and Shape:SolidMolecular weight:1399.69,10-Dihydrophenanthrene
CAS:<p>9,10-Dihydrophenanthrene has inhibitory activity against the androgen receptor and can be used in related research in the field of life sciences.</p>Formula:C14H12Purity:98.76%Color and Shape:SolidMolecular weight:180.25Antihypertensive agent 3
<p>Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs</p>Formula:C16H13NO4SColor and Shape:SolidMolecular weight:315.34DPC-AJ1951
CAS:<p>Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).</p>Formula:C76H127N23O19Purity:98%Color and Shape:SolidMolecular weight:1666.98PROTAC ERα Degrader-2
CAS:<p>PROTAC ERα Degrader-2 is composed of a cIAP1 ligand binding group, a linker, and an estrogen receptor α (ERα) binding group, serving as an ERα degrader.</p>Formula:C42H61N5O8Purity:98%Color and Shape:SolidMolecular weight:763.96PROTAC ER Degrader-3
CAS:<p>PROTAC ER Degrader-3 from patent WO2017201449A1 is a PAC synthesis intermediate for ADC/PROTAC antibody conjugates, boosting ERα degradation.</p>Formula:C71H77N7O12Purity:98%Color and Shape:SolidMolecular weight:1220.434Epi-Cryptoacetalide
<p>Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054.</p>Formula:C18H22O3Color and Shape:SolidMolecular weight:286.371(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin
CAS:<p>'(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin blocks oxytocin receptors, stopping oxytocin effects on CA1 neuron currents.'</p>Formula:C45H69N9O12S2Color and Shape:SolidMolecular weight:992.21Camizestrant TFA
<p>Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).</p>Formula:C26H29F7N6O2Purity:98.9%Color and Shape:SoildMolecular weight:590.54Nociceptin (1-13), amide
CAS:<p>Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain</p>Formula:C61H100N22O15Purity:98%Color and Shape:SolidMolecular weight:1381.59ERD-3111
CAS:<p>ERD-3111 (Compound 44), an orally active PROTAC ERα degrader (DC50: 0.5 nM), exhibits efficacy in inhibiting tumor growth in both the parental MCF-7 xenograft</p>Formula:C45H46F4N8O5Purity:98%Color and Shape:SolidMolecular weight:854.89Dexamethasone phosphate
CAS:<p>Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.</p>Formula:C22H30FO8PColor and Shape:SolidMolecular weight:472.4418-Oxocortisol
CAS:<p>18-Oxocortisol, a naturally occurring mineralocorticoid and adrenal biomarker, is produced by CYP11B2.</p>Formula:C21H28O6Color and Shape:SolidMolecular weight:376.449Tibolone
CAS:<p>Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the</p>Formula:C21H28O2Purity:99.70% - 99.71%Color and Shape:White To Off-White Crystalline PowderMolecular weight:312.45Ac-RYYRWK-NH2
CAS:<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Formula:C49H69N15O9Purity:98%Color and Shape:SolidMolecular weight:1012.17Galloylalbiflorin
CAS:<p>Galloylalbiflorin, an AR antagonist with IC50 53.3μM, is sourced from Paeonia lactiflora roots, exhibiting anti-androgenic properties.</p>Formula:C30H32O15Color and Shape:SolidMolecular weight:632.57Olmesartan impurity
CAS:<p>Olmesartan impurity, related to parent RNH-6270, is an AT1R antagonist used for hypertension research.</p>Formula:C33H26N4OColor and Shape:SolidMolecular weight:494.598[Nphe1]Nociceptin(1-13)NH2 TFA
<p>[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.</p>Formula:C63H101F3N22O17Color and Shape:SolidMolecular weight:1495.61Aclerastide
CAS:<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Formula:C42H64N12O11Color and Shape:SolidMolecular weight:913.03Floramanoside C
CAS:<p>Floramanoside C exhibits 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities [1].</p>Formula:C21H18O15Color and Shape:SolidMolecular weight:510.36[Ala17]-MCH TFA
<p>'[Ala17]-MCH TFA is an MCH analogue, a selective MCHR1 ligand (Ki=0.16 nM) with high affinity (Kd=0.37 nM), and low MCHR2 affinity (Ki=34 nM).</p>Formula:C99H156F3N29O28S4Color and Shape:SolidMolecular weight:2385.73[Sar1, Ile8]-Angiotensin II TFA
<p>[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.</p>Formula:C48H74F3N13O12Purity:98%Color and Shape:SolidMolecular weight:1082.18difelikefalin acetate(1024828-77-0 Free base)
CAS:<p>is a ketone and a building block.</p>Formula:C38H57N7O8Purity:96.94%Color and Shape:SolidMolecular weight:739.9OX04528
CAS:<p>OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.</p>Formula:C16H13F6NO2Purity:99.74%Color and Shape:SoildMolecular weight:365.27Ac-RYYRWK-NH2 TFA
CAS:<p>Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.</p>Formula:C51H70F3N15O11Color and Shape:SolidMolecular weight:1126.21THR-β agonist 2 diacetate
<p>THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.</p>Color and Shape:Odour SolidMCH(human, mouse, rat) TFA
<p>MCH TFA, a peptide, selectively binds MCH1R and MCH2R with IC50 of 0.3nM, 1.5nM; EC50s are 3.9nM (MCH1R) and 0.1nM (MCH2R) in CHO cells.</p>Formula:C107H161F3N30O28S4Color and Shape:SolidMolecular weight:2500.86PRL 3195
CAS:<p>PRL 3195: Somatostatin antagonist, Ki: 6 nM (sst5), 17 nM (sst2), 66 nM (sst3), 1 μM (sst1/4).</p>Formula:C58H69ClN12O9S2Color and Shape:SolidMolecular weight:1177.83[Met5]-Enkephalin, amide
CAS:<p>[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.</p>Formula:C27H36N6O6SPurity:98%Color and Shape:SolidMolecular weight:572.68Deacylcortivazol
CAS:<p>Deacylcortivazol is a potent glucocorticoid that inhibits growth in glucocorticoid-resistant leukemia cells without receptor mediation.</p>Formula:C30H36N2O4Color and Shape:SolidMolecular weight:488.62ALR2-IN-6
<p>ALR2-IN-6 (compound 9) is a potent competitive inhibitor of ALR2, with a Ki value of 0.064 μM. It is applicable in research related to neuropathy, retinopathy, and nephropathy.</p>Formula:C21H19BrFN3OColor and Shape:SolidMolecular weight:427.06955ERD-1233
<p>ERD-1233 is an effective oral PROTAC degrader of the estrogen receptor (estrogen receptor) with a DC50 of 0.9 nM. It plays a crucial role in research involving ER+ breast cancer.</p>Formula:C49H53N5O6Color and Shape:SolidMolecular weight:807.98Cgp 44099
CAS:<p>Cgp 44099 is a potent plasma renin inhibitor from all subprimate species.</p>Formula:C69H104N14O13Purity:98%Color and Shape:SolidMolecular weight:1337.676UFP-101 acetate
<p>UFP-101 acetate is a selective and competitive antagonist of the NOP receptor (pKi = 10.24) with >3000-fold selectivity over δ, μ, and κ opioid receptors.</p>Formula:C84H142N32O23Purity:95.92%Color and Shape:SolidMolecular weight:1968.23PSDalpha
<p>PSDalpha, a conjugate of PS, TB, and 17β-estradiol, degrades ERα with peak absorption at 465 nm, effectively inhibiting MCF-7 cell growth.</p>Formula:C44H39N3O2SColor and Shape:SolidMolecular weight:673.86CTOP acetate
<p>CTOP acetate is a somatostatin analogue and a μ-opioid receptor antagonist.</p>Formula:C52H71N11O13S2Purity:99.87%Color and Shape:SoildMolecular weight:1122.32β-Endorphin (rat)
CAS:<p>β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.</p>Formula:C157H254N42O44SColor and Shape:SolidMolecular weight:3466.07[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
CAS:<p>'[DAla2, DArg6] Dynorphin A (1-13) porcine is a potent opioid peptide resistant to enzymatic degradation.'</p>Formula:C76H128N24O15Color and Shape:SolidMolecular weight:1617.98Dynorphin B (1-13) (TFA)
<p>Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .</p>Formula:C76H116N21F3O19Color and Shape:SolidMolecular weight:1684.86Imlunestrant tosylate
CAS:<p>Imlunestrant (LY-3484356) tosylate, an oral SERD, targets ER+ aBC/EEC by blocking estrogen receptors and gene transcription.</p>Formula:C36H32F4N2O6SColor and Shape:SolidMolecular weight:696.71β-Lipotropin (60-65)
CAS:<p>β-Lipotropin (60-65) (β-LPH (60-65)), an opioid agonist, is a significant [1] opioid peptide.</p>Formula:C33H47N9O8SColor and Shape:SolidMolecular weight:729.85Helianorphin-19
<p>Helianorphin-19: Potent KOR agonist (Ki=25 nM; EC50=45 nM), 200x selective over μ/δ receptors, effective in mouse pain model, non-sedative.</p>Color and Shape:LiquidDP32
CAS:<p>DP32 is a dual-function compound incorporating an opioid receptor (MOP) agonist and a neuropeptide FF receptor (NPFFR) antagonist. It is applicable in analgesia-related research.</p>Formula:C57H77N13O7Color and Shape:SolidMolecular weight:1056.30BWA-6047
<p>BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.</p>Formula:C42H46ClN5O7Color and Shape:SolidMolecular weight:767.30858Zankiren
CAS:<p>Zankiren is a renin inhibitor. Zankiren can reduce blood pressure, plasma renin activity, and angiotension II.</p>Formula:C35H55N5O6S2Color and Shape:SolidMolecular weight:705.97Kylo-0603
CAS:<p>KYLO-0603 is an orally active and selective THR-β agonist with an EC50 of 31.07 nM. It effectively reduces serum cholesterol and low-density lipoprotein cholesterol levels. By activating THR-β receptors, KYLO-0603 enhances the expression of THR-regulated genes like iodothyronine deiodinase 1 (Dio1), malic enzyme 1 (Me1), and thyroid hormone-responsive (Thrsp) gene, while it inhibits the expression of inflammatory and fibrosis-related genes, including low-density lipoprotein receptor (LDL-R) gene. This compound is applicable for the study of metabolic associated steatohepatitis (MASH) and liver fibrosis.</p>Formula:C81H134N8O28Color and Shape:SolidMolecular weight:1667.97Raloxifene 4'-glucuronide
CAS:<p>Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene.</p>Formula:C34H35NO10SPurity:98%Color and Shape:SolidMolecular weight:649.71(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS:<p>E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid</p>Formula:C50H81N15O9Color and Shape:SolidMolecular weight:1036.27PD 125967
CAS:<p>PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.</p>Formula:C51H67N5O4Color and Shape:SolidMolecular weight:814.11UFP-803
CAS:<p>UT receptor ligand acts mainly as silent antagonist with slight agonist effects; blocks U-II in rat aorta, pIC50 = 7.46, & inhibits plasma leakage in mice.</p>Formula:C50H64N10O12S2Purity:98%Color and Shape:SolidMolecular weight:1061.24Abaloparatide
CAS:<p>Abaloparatide (BA 058) is a selective PTHR1 analog that promotes bone growth and may be researched for osteoporosis.</p>Formula:C174H300N56O49Color and Shape:SolidMolecular weight:3960.59TF-505
CAS:<p>TF-505, a steroid 5α-reductase inhibitor, is used potentially for the treatment of benign prostatic hyperplasia.</p>Formula:C33H37NO4Purity:98%Color and Shape:SolidMolecular weight:511.65T4-ATA (S-isomer)
<p>T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.</p>Formula:C19H15I4NO6SPurity:98%Color and Shape:SolidMolecular weight:893.01Raloxifene 4-Monomethyl Ether
CAS:<p>Raloxifene 4-Monomethyl Ether (Compound 37), an estrogen receptor α inhibitor, has an IC50 of 1 μM against MCF-7 cells.</p>Formula:C29H29NO4SColor and Shape:SolidMolecular weight:487.61Nocistatin
CAS:<p>Nocistatin, a neuropeptide, blocks Nociceptin effects and inhibits 5-HT release, acting on an opioid-related receptor.</p>Formula:C32H56N10O12Color and Shape:SolidMolecular weight:772.85BMS-903452
CAS:<p>BMS-903452: potent GPR119 agonist, EC50 = 14 nM, treats rodent diabetes, no P450 inhibition, safe for liver cells.</p>Formula:C21H19Cl2FN4O4SPurity:99.76% - >99.99%Color and Shape:SolidMolecular weight:513.37SNIPER(ER)-87
CAS:<p>SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (</p>Formula:C59H73N5O10SPurity:98%Color and Shape:SolidMolecular weight:1044.32CGP-42112 acetate
<p>CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.</p>Formula:C54H73N13O13Purity:99.06% - 99.92%Color and Shape:SoildMolecular weight:1112.24ERα degrader 6
<p>ERα degrader 6 (Compound 31q) is an ERα degrader with a K I of 75 nM and also inhibits ARO with an IC50 value of 37.7 nM.</p>Formula:C28H23F3N4O4SPurity:98%Color and Shape:SolidMolecular weight:568.57Neuropeptide AF (human) acetate
<p>Neuropeptide AF (human) acetate (Neuropeptide AF (human) acetate (192387-38-5 Free base)) is an anti-opioid neuropeptide, a Neuropeptide AF (human) derivative,</p>Purity:99.89%Color and Shape:SoildSNIPER(ER)-110
<p>SNIPER(ER)-110 links cIAP1 and estrogen ligands. SNIPER(ER)-51 degrades ER protein; DC50 <3 nM at 4h, 7.7 nM at 48h.</p>Formula:C66H83N5O11Purity:98%Color and Shape:SolidMolecular weight:1122.39ZINC05925939
<p>ZINC05925939 is an estrogen receptor β (ESR2) inhibitor used in breast cancer research.</p>Formula:C17H17NO2Color and Shape:SolidMolecular weight:267.321-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
CAS:<p>1-Methyl-quinolone alkaloid inhibits DAG acyltransferase, blocks angiotensin II receptor (IC50s: 20.1 & 34.1 μM), and fights H. pylori (MIC: 10 μg/mL).</p>Formula:C23H31NOColor and Shape:SolidMolecular weight:337.5Retosiban
CAS:<p>Retosiban is an effective and selective oxytocin antagonist (Ki: 0.65 nM).</p>Formula:C27H34N4O5Purity:98%Color and Shape:SolidMolecular weight:494.58Norleual
CAS:<p>Angiotensin IV analog, potent HGF/c-MET inhibitor (IC50=3 pM), halts MDCK cell growth and invasion, AT4 antagonist, impairs LTP, antiangiogenic.</p>Formula:C41H58N8O7Purity:98%Color and Shape:SolidMolecular weight:774.95[Orn8]-Urotensin II
CAS:<p>[Orn8]-Urotensin II is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.</p>Formula:C63H83N13O18S2Color and Shape:SolidMolecular weight:1374.55R4K1
<p>R4K1 is a cell-permeable stapled peptide that binds with high affinity to estrogen receptor (ER) α, inhibiting its interaction with coactivators. It penetrates breast cancer cells, regulating gene transcription and suppressing cell proliferation. R4K1 is applicable for tumor research.</p>Formula:C82H146N34O19Color and Shape:SolidMolecular weight:1912.25Latanoprost acid
CAS:<p>Latanoprost acid is a prostanoid receptor agonist that blocks RANKL and can be used to reduce intraocular pressure.</p>Formula:C23H34O5Purity:97.96%Color and Shape:Pale Yellow OilMolecular weight:390.51Urotensin II (114-124), human TFA
<p>Urotensin II (114-124), human TFA, is an 11-amino acid peptide and potent vasoconstrictor, acting as GPR14 agonist.</p>Formula:C66H86F3N13O20S2Purity:98%Color and Shape:SolidMolecular weight:1502.59AKR1Cs-IN-1
<p>AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.</p>Color and Shape:Odour SolidTLB 150 Benzoate
CAS:<p>TLB 150 Benzoate (RAD150) is a modulator of the androgen receptor with an IC50 value of 0.13 μM.</p>Formula:C27H20ClN5O3Color and Shape:SolidMolecular weight:497.93AR antagonist 9
<p>AR antagonist 9 is an orally active, selective androgen receptor (AR) antagonist that inhibits cancer by disrupting the formation of AR ligand-binding domain dimers, showing potential in overcoming drug resistance in prostate cancer (PCa). Its antagonistic activity against AR has an IC50 of 0.051 μM, comparable to Enzalutamide (IC50= 0.060 μM). This compound demonstrates superior inhibitory effects on ARF876L/T877A and ARW741C mutants compared to Enzalutamide. Additionally, AR antagonist 9 possesses favorable pharmacokinetic properties, with an oral bioavailability (F) of 66.24% in rats, and significantly inhibits tumor growth in LNCaP xenograft mouse models upon oral administration. AR antagonist 9 holds promise for research in overcoming PCa resistance.</p>Formula:C18H13F4NO2Color and Shape:SolidMolecular weight:351.29Gridegalutamide
CAS:<p>Gridegalutamide exhibits anti-androgen and anti-tumor activities.</p>Formula:C41H45F3N8O5SColor and Shape:SolidMolecular weight:818.91Emd 55068
CAS:<p>Emd 55068 is a synthetic antagonist of renin.</p>Formula:C41H65N9O6Color and Shape:SolidMolecular weight:780.01A 779
CAS:<p>A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.</p>Formula:C39H60N12O11Purity:98%Color and Shape:SolidMolecular weight:872.97RLA-5331
<p>RLA-5331: iron activator with anti-androgen properties; inhibits mCRPC cell proliferation.</p>Formula:C40H43F3N6O7SColor and Shape:SolidMolecular weight:808.87Cgp 29287
CAS:<p>Cgp 29287 is a primate-specific renin inhibitor. It also has a prolonged duration of action.</p>Formula:C72H110N20O15Color and Shape:SolidMolecular weight:1495.77Enclomiphene-d4
<p>Enclomiphene-d4 is the deuterium-labeled analog of Enclomiphene. Enclomiphene functions as a potent and orally active estrogen receptor antagonist, exhibiting antiestrogenic properties.</p>Color and Shape:Odour SolidNorethindrone acetate
CAS:<p>Norethindrone acetate (19-Norethindroneacetate) is an oestrogen with inhibitory effects on adolescent menstruation and hepatic adenomas and is often used in</p>Formula:C22H28O3Purity:99.4%Color and Shape:SolidMolecular weight:340.46ERα/ERβ antagonist-1
CAS:<p>ERα/ERβ antagonist-1 (Compound 10) functions as a partial antagonist of both ERα and ERβ. It reduces the activity of ERα and ERβ in HepG2 liver cells in a dose-dependent manner.</p>Formula:C22H24O3Color and Shape:SolidMolecular weight:336.42BI 653048 phosphate
CAS:<p>BI 653048 phosphate is a selective and orally active agonist of nonsteroidal glucocorticoid (GC)(IC50 : 55 nM).</p>Formula:C23H28F4N3O8PSPurity:98%Color and Shape:SolidMolecular weight:613.52BigLEN(rat)
CAS:<p>Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.</p>Formula:C76H128N24O23Purity:98%Color and Shape:SolidMolecular weight:1746Hydrocortisone sodium succinate
CAS:<p>Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.</p>Formula:C25H34NaO8Color and Shape:SolidMolecular weight:485.529PROTAC AR-V7 degrader-1
CAS:<p>Potent, oral AR-V7 degrader (Compound 6); DC50: 0.32µM; targets AR-DBD via VHL E3; EC50: 0.88µM in 22Rv1 cells.</p>Formula:C41H52N6O6S2Color and Shape:SolidMolecular weight:789.02L 363564
CAS:<p>L 363564 is a kidney renin inhibitor.</p>Formula:C54H76N12O10Color and Shape:SolidMolecular weight:1053.276Orphine
CAS:<p>Orphine is an opioid compound that can amplify the antinociceptive effects reduced by naloxone in mice.</p>Formula:C20H23N3OColor and Shape:SolidMolecular weight:321.42Lyciumin A
CAS:<p>Lyciumin A, a cyclic octapeptide, inhibits proteases and could aid in hypertension studies.</p>Formula:C42H51N9O12Color and Shape:SolidMolecular weight:873.921ER degrader 5
CAS:<p>ER degrader 5: potent ER degrader, anti-cancer, for breast cancer research.</p>Formula:C26H18F2O4SColor and Shape:SolidMolecular weight:464.48Brain Natriuretic Peptide (1-32), rat
CAS:<p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>Formula:C146H239N47O44S3Purity:98%Color and Shape:SolidMolecular weight:3452.94Alunacedase alfa
CAS:<p>Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.</p>Purity:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Color and Shape:LiquidHINT1-IN-1
<p>HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).</p>Formula:C23H24N8O5Color and Shape:SolidMolecular weight:492.49Ro 64-6198
CAS:<p>Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.</p>Formula:C26H31N3OPurity:98%Color and Shape:SolidMolecular weight:401.54Azilsartan Medoxomil Potassium
CAS:<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Formula:C30H23N4O8·KPurity:98.72%Color and Shape:SolidMolecular weight:606.62PTP1B/AKR1B1-IN-2
<p>PTP1B/AKR1B1-IN-2 (Compound 7f) is a potent inhibitor targeting both PTP1B and AKR1B1 with IC50 values of 3.2 and 2.1 μM, respectively, and K i values of 4.0</p>Formula:C23H23NO4S2Purity:98%Color and Shape:SolidMolecular weight:441.56C-Type Natriuretic Peptide (1-53), human
CAS:<p>CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.</p>Formula:C251H417N81O71S3Purity:98%Color and Shape:SolidMolecular weight:5801.77hFSH-β-(33-53) (TFA)
<p>hFSH-β-(33-53) TFA, a thiol-containing peptide representing the second follicle-stimulating hormone receptor (FSHR) binding domain, acts as an FSHR antagonist.</p>Formula:C115H183N31O32SxC2HF3O2Color and Shape:SolidMolecular weight:2657.96BIBS 39
CAS:<p>BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.</p>Formula:C32H36N4O3Purity:99.28%Color and Shape:SolidMolecular weight:524.65Estrogen receptor modulator 6
CAS:<p>ER modulator 6 (3a) is a potent ERβ agonist with a K i of 0.44 nM; 19x more selective for ERβ than ERα.</p>Formula:C18H16F2O3Color and Shape:SolidMolecular weight:318.32PD 123177
CAS:<p>PD 123177 is an inhibitor of Nonpeptide angiotensin AII-2.</p>Formula:C29H28N4O3Purity:98%Color and Shape:SolidMolecular weight:480.56TRV055 acetate
<p>TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.</p>Formula:C44H61N9O11Purity:99.84%Color and Shape:SolidMolecular weight:892.0117-Epiestriol
CAS:<p>17-Epiestriol, metabolite of estrone, forms via 16α-hydroxy intermediate and binds ERα and ERβ with affinity less than 17β-estradiol.</p>Formula:C18H24O3Color and Shape:SolidMolecular weight:288.38AZ 1729
CAS:<p>FFA2 modulator; inhibits cAMP, enhances 35SGTPγS binding (pEC50: 6.9, 7.23); alters Gi/Gq signaling; affects lipolysis, neutrophil migration.</p>Formula:C18H16FN5OSColor and Shape:SolidMolecular weight:369.42RLA-4842
<p>RLA-4842: iron-based anti-androgen; inhibits mCRPC cell proliferation.</p>Formula:C42H46F3N5O8SColor and Shape:SolidMolecular weight:837.94A7C-301
<p>4A7C-301, a Nurr1 agonist, exhibits potent neuroprotective effects in vitro and markedly mitigates neuropathological abnormalities while enhancing motor and</p>Color and Shape:Odour SolidKOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formula:C21H25N3Color and Shape:SolidMolecular weight:319.44PROTAC ERRα Degrader-3
CAS:<p>PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERRα protein.</p>Formula:C47H50F6N6O7SColor and Shape:SolidMolecular weight:957.0ARCC-4
CAS:<p>ARCC-4: A VHL-recruiting, low-nanomolar (DC50=5nM) AR degrader; outshines enzalutamide; degrades AR mutants resistant to therapy.</p>Formula:C53H56F3N7O7S2Purity:98%Color and Shape:SolidMolecular weight:1024.18Parathyroid hormone (1-34) (rat)
CAS:<p>Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.</p>Formula:C180H291N55O48S2Purity:98%Color and Shape:SolidMolecular weight:4057.74Biphalin TFA
CAS:<p>Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.</p>Formula:C46H56N10O10·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:909.00 (free base)Perindoprilat
CAS:<p>Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.</p>Formula:C17H28N2O5Purity:99.48%Color and Shape:SolidMolecular weight:340.41Betamethasone acibutate
CAS:<p>Betamethasone acibutate, a glucocorticoid, is derived from Betamethasone.</p>Formula:C28H37FO7Purity:98%Color and Shape:SolidMolecular weight:504.59Remikiren
CAS:<p>Remikiren is a highly specific renin inhibitor with oral activity for the treatment of hypertensio.</p>Formula:C33H50N4O6SColor and Shape:SolidMolecular weight:630.84(S)-CVN424
CAS:<p>(S)-CVN424 modulates GPR6, key for neurological/psychiatric research, including Parkinson's.</p>Formula:C24H29F2N5O3Color and Shape:SolidMolecular weight:473.5252-Ethylhexyl trans-4-methoxycinnamate
CAS:<p>2-Ethylhexyl trans-4-methoxycinnamate is a sunscreen agent.</p>Formula:C18H26O3Purity:98.92%Color and Shape:Pale Yellow LiquidMolecular weight:290.4Urotensin II, mouse
CAS:<p>UTS2 is a human gene, alias U-II, on chromosome 1p36.23, codes for Urotensin-II, a potent vasoconstrictor. Formula: C64H85N13O18S2, Molar mass: 1388.6 g/mol.</p>Formula:C76H100N18O19S2Purity:98%Color and Shape:SolidMolecular weight:1633.86TRV056
CAS:<p>TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.</p>Formula:C52H74N14O13Color and Shape:SolidMolecular weight:1103.249Angiotensin amide
CAS:<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Formula:C49H70N14O11Purity:98%Color and Shape:SolidMolecular weight:1031.17AKR1B10-IN-1
CAS:<p>AKR1B10-IN-1: potent AKR1B10 inhibitor, IC50 3.5 nM; hinders lung cancer cell growth, spread, and Cisplatin resistance.</p>Formula:C19H16FNO4Color and Shape:SolidMolecular weight:341.338UFP-101
CAS:<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Formula:C82H138N32O21Purity:98%Color and Shape:SolidMolecular weight:1908.194'-hydroxy Tamoxifen
CAS:<p>It is a metabolite of tamoxifen and an estrogen receptor modulator.</p>Formula:C26H29NO2Purity:98%Color and Shape:SolidMolecular weight:387.511α-Hydroxy-3-epi-vitamin D3
CAS:<p>1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].</p>Formula:C27H44O2Color and Shape:SolidMolecular weight:400.647PROTAC AR Degrader-4 TFA
<p>PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.</p>Formula:C45H68F3N3O11Color and Shape:SolidMolecular weight:884.03U-54494A hydrochloride
CAS:<p>U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.</p>Formula:C18H25Cl3N2OColor and Shape:SolidMolecular weight:391.76PROTAC ERRα Degrader-2
CAS:<p>PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group.</p>Formula:C57H55Cl2F6N7O8Purity:98%Color and Shape:SolidMolecular weight:1150.99Ac-RYYRIK-NH2
CAS:<p>NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.</p>Formula:C44H70N14O9Purity:98%Color and Shape:SolidMolecular weight:939.12Prepro-TRH-(160-169)
CAS:<p>Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.</p>Formula:C54H75N11O18SColor and Shape:SolidMolecular weight:1198.3PROTAC ER Degrader-15
<p>PROTAC ER Degrader-15 (Compound 40) is an orally active estrogen receptor (ER) degrader with anticancer properties, suitable for breast cancer research.</p>Formula:C47H47F4N5O5Color and Shape:SolidMolecular weight:837.9Antitumor agent-195
<p>Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.</p>Formula:C22H22N2O4Color and Shape:SolidMolecular weight:378.42Aliskiren D6 Hydrochloride
CAS:<p>Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).</p>Formula:C30H54ClN3O6Purity:98%Color and Shape:SolidMolecular weight:594.26[Sar1, Ile8]-Angiotensin II acetate
<p>'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.</p>Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2PL-017
CAS:<p>μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.</p>Formula:C29H37N5O5Purity:98%Color and Shape:SolidMolecular weight:535.64PROTAC ERα Degrader-7
CAS:<p>PROTAC ERα Degrader-7 (Compound i-320) is a powerful PROTAC degrader targeting the estrogen receptor alpha (ERα), exhibiting a DC50 of 0.000006 µM. This compound consists of a cereblon-binding segment, LBM, connected to ERBM, an ERα-binding ligand that includes a benzofused partially saturated 6-membered carbocyclic or heterocyclic ring [1].</p>Formula:C46H49F2N5O4Color and Shape:SolidMolecular weight:773.91Melanin Concentrating Hormone, salmon TFA
<p>MCH (salmon) TFA is a 19-amino-acid neuropeptide affecting appetite, energy, sleep, and heart health via GPCR SLC-1/GPR24 and MCHR2.</p>Formula:C91H140F3N27O26S4Color and Shape:SolidMolecular weight:2213.5BigLEN(mouse)
CAS:<p>GPR171 agonist from ProSAAS controls mouse appetite, reduces glutamate in paraventricular neurons via G protein.</p>Formula:C78H130N24O22Purity:98%Color and Shape:SolidMolecular weight:1756.03(rel)-PROTAC ERRα Degrader-1
<p>(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1, which is an estrogen-related receptor alpha (ERRa) degrader.</p>Formula:C54H49Cl2F6N7O8Purity:98%Color and Shape:SolidMolecular weight:1108.91PROTAC ERα Degrader-8
CAS:<p>PROTAC ERα Degrader-8 (compound ii-56), a highly potent degrader of Erα, achieves a DC50 of just 0.000006 μM in MCF7 cells [1].</p>Formula:C47H51N5O4Color and Shape:SolidMolecular weight:749.94PROTAC ER Degrader-4
CAS:<p>PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).</p>Formula:C53H67F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:1005.2[Arg14,Lys15]Nociceptin
CAS:<p>Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>Formula:C82H137N31O22Purity:98%Color and Shape:SolidMolecular weight:1909.18Herkinorin
CAS:<p>Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.</p>Formula:C28H30O8Color and Shape:SolidMolecular weight:494.53Estrone-N-O-C1-amido
CAS:<p>Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα).</p>Formula:C20H26N2O3Purity:98%Color and Shape:SolidMolecular weight:342.439DAMGO (TFA)
CAS:<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Formula:C28H36F3N5O8Purity:98%Color and Shape:SolidMolecular weight:627.61OT-R antagonist 2
CAS:<p>OT-R antagonist 2 is a nonpeptide low molecular weight antagonist of OT-R .</p>Formula:C28H29N3O4Purity:98%Color and Shape:SolidMolecular weight:471.55BI 653048
CAS:<p>BI 653048 is a selective and orally active agonist of nonsteroidal glucocorticoid (IC50: 55 nM). BI 653048 is also an HCV NS3 protease inhibitor.</p>Formula:C23H25F4N3O4SPurity:98%Color and Shape:SolidMolecular weight:515.523-epi-25-hydroxy Vitamin D3
CAS:<p>3-epi-25-hydroxy Vitamin D3 lowers serum PTH in male weanling rats at 0.5 and 1 IU/g doses; doesn't affect females.</p>Formula:C27H44O2Color and Shape:SolidMolecular weight:400.64GNE-274
CAS:<p>GNE-274, akin to GDC-0927 but non-degrading, is a partial ER agonist in breast cancer, enhancing chromatin at ER sites, inhibiting ER-LBD.</p>Formula:C29H31NO4Color and Shape:SolidMolecular weight:457.57Zavacorilant
CAS:<p>Zavacorilant is capable of modulating glucocorticoid receptor (GR).</p>Formula:C25H26FN7O3S2Color and Shape:SolidMolecular weight:555.65NH-3
CAS:<p>NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.</p>Formula:C28H27NO6Purity:97.79% - 99.40%Color and Shape:SolidMolecular weight:473.52Naldemedine
CAS:<p>Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.</p>Formula:C32H34N4O6Color and Shape:SolidMolecular weight:570.64Cgp 38560
CAS:<p>CGP 38560 is a potent renin inhibitor.</p>Formula:C40H67N5O9S2Color and Shape:SolidMolecular weight:826.12Dipropyl phthalate
CAS:<p>Dipropyl phthalate is a weak androgen receptor inhibitor, and can be used in biochemical experiments and drug synthesis.</p>Formula:C14H18O4Purity:98.62%Color and Shape:SolidMolecular weight:250.29Methylpiperidino pyrazole
CAS:<p>Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression.</p>Formula:C29H31N3O3Purity:98.84%Color and Shape:SolidMolecular weight:469.57ST-CY14
<p>ST-CY14 is an inhibitor of the Nur77-PPARγ interaction with an EC50 of 3.15 μM. It binds to Nur77 (Kd=32 nM) to prevent its ubiquitination and degradation by PPARγ, reducing fatty acid uptake and mitochondrial respiration, and inhibiting the transcription of CD36 and FABP4. ST-CY14 suppresses proliferation and migration of MCF7 and MDA-MB-231 cancer cells and impedes tumor growth and bone metastasis in mouse models.</p>Formula:C139H237N57O31S2Color and Shape:SolidMolecular weight:3266.86OBHSA
CAS:<p>OBHSA（Oxabicycloheptane sulfonamide） is a novel selective estrogen receptor depressant (SERD) that can be used to study breast cancer.</p>Formula:C27H24F3NO6SPurity:98%Color and Shape:SolidMolecular weight:547.543-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Color and Shape:Odour SolidDDHF20
<p>DDHF20 is an inhibitor of Staphylococcus aureus, specifically targeting and inhibiting its thioredoxin reductase (TrxR) by acting as a competitive inhibitor at the NADPH binding site. DDHF20 shows potential for research in combating infections related to Staphylococcus aureus.</p>Formula:C34H28O4Color and Shape:SolidMolecular weight:500.58Teriparatide
CAS:<p>Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).</p>Formula:C181H291N55O51S2Purity:98%Color and Shape:SolidMolecular weight:4117.72Axelopran
CAS:<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Formula:C26H39N3O4Color and Shape:SolidMolecular weight:457.614,4'-(Cyclohexylidenemethylene)diphenol
CAS:<p>4,4'-(Cyclohexylidenemethylene)diphenol (Compound 2) is a symmetrical cyclic non-steroidal estrogen. It exhibits high binding affinity to estrogen receptors ERα and ERβ.</p>Formula:C19H20O2Color and Shape:SolidMolecular weight:280.36Neuropeptide AF (human)
CAS:<p>Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.</p>Formula:C90H132N26O25Purity:98%Color and Shape:SolidMolecular weight:1978.17PTP1B/AKR1B1-IN-1
<p>PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s</p>Formula:C22H21NO4S2Purity:98%Color and Shape:SolidMolecular weight:427.54ET receptor antagonist 2
<p>ET Receptor Antagonist 2 (Compound 16j) is an orally active ET receptor antagonist with an IC50 of 0.22 nM, suitable for pulmonary arterial hypertension (PAH)</p>Formula:C22H25N5O5SPurity:98%Color and Shape:SolidMolecular weight:471.53(E)-4-Hydroxytamoxifen
CAS:<p>(E)-4-Hydroxytamoxifen is a less active isomer of (Z)-4-hydroxytamoxifen and also is an estrogen receptor modulator.</p>Formula:C26H29NO2Color and Shape:SolidMolecular weight:387.51SCO-267
CAS:<p>SCO-267 is a full agonist of GPR40/FFAR1， stimulating insulin secretion and GLP-1 release in diabetic rats, improving glucose tolerance,type 2 diabetes.</p>Formula:C36H46N4O5Purity:99.89%Color and Shape:SolidMolecular weight:614.77
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