Endocrinology/Hormones

Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.

Subcategories of "Endocrinology/Hormones"

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Found 3183 products of "Endocrinology/Hormones"

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Betamethasone acibutate
CAS:
- 5534-05-4
Betamethasone acibutate, a glucocorticoid, is derived from Betamethasone.
Formula:C₂₈H₃₇FO₇
Purity:98%
Color and Shape:Solid
Molecular weight:504.59
Ref: TM-T13579
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PSDalpha
PSDalpha, a conjugate of PS, TB, and 17β-estradiol, degrades ERα with peak absorption at 465 nm, effectively inhibiting MCF-7 cell growth.
Formula:C₄₄H₃₉N₃O₂S
Color and Shape:Solid
Molecular weight:673.86
Ref: TM-T74335
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ARD-2585
CAS:
- 2757422-79-8
ARD-2585 is an orally active and selective androgen receptor PROTAC degrader with anticancer activity for the study of prostate cancer.
Formula:C₄₁H₄₃ClN₈O₅
Color and Shape:Solid
Molecular weight:763.28
Ref: TM-T74141
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CP 85339
CAS:
- 119625-53-5
CP 85339 is an aspartic acid protease inhibitor for X-ray analysis of peptide-renin complexes.
Formula:C₃₁H₄₉ClN₄O₆S
Color and Shape:Solid
Molecular weight:641.26
Ref: TM-T31035
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Raloxifene 4'-glucuronide
CAS:
- 182507-22-8
Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene.
Formula:C₃₄H₃₅NO₁₀S
Purity:98%
Color and Shape:Solid
Molecular weight:649.71
Ref: TM-T12686
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Osteostatin
CAS:
- 138949-73-2
Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting
Formula:C₂₇H₄₁N₉O₈
Color and Shape:Solid
Molecular weight:619.67
Ref: TM-T81592
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Vasopressin Dimer (parallel) (TFA)
Vasopressin Dimer (parallel) TFA, a parallel dimer of Vasopressin, has the capability to activate four G protein-coupled receptors—namely, V1aR, V1bR, V2R, and
Formula:C₉₄H₁₃₁F₃N₃₀O₂₆S₄
Purity:98%
Color and Shape:Solid
Molecular weight:2282.49
Ref: TM-T80197
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Dynorphin A (1-10)
CAS:
- 79994-24-4
Dynorphin A (1-10) is an opioid peptide, binds κ-opioid receptor, blocks NMDA current, IC50: 42.0 μM.
Formula:C₅₇H₉₁N₁₉O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1234.45
Ref: TM-TP1813
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Glucocorticoids receptor agonist 2
CAS:
- 614761-20-5
Arylpyrazole-based glucocorticoid agonist with potent anti-inflammatory effects; doesn't affect insulin secretion.
Formula:C₂₅H₂₅FN₂O
Color and Shape:Solid
Molecular weight:388.48
Ref: TM-T40697
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GNE-502
CAS:
- 1953134-16-1
GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.
Formula:C₂₅H₃₀FN₃O₃S
Color and Shape:Solid
Molecular weight:471.59
Ref: TM-T39369
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TD-802
CAS:
- 2760703-21-5
TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.
Formula:C₅₂H₆₁ClN₁₀O₆
Color and Shape:Solid
Molecular weight:957.56
Ref: TM-T74520
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Chlorothiazide
CAS:
- 58-94-6
Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.
Formula:C₇H₆ClN₃O₄S₂
Purity:98.46% - 98.91%
Color and Shape:Crystals Physical Description Crystals; White Powder (Ntp 1992)
Molecular weight:295.72
Ref: TM-T0677
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PD 125967
CAS:
- 128139-14-0
PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.
Formula:C₅₁H₆₇N₅O₄
Color and Shape:Solid
Molecular weight:814.11
Ref: TM-T28324
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Clocinnamox mesylate
CAS:
- 117332-69-1
Clocinnamox mesylate: irreversible μ-opioid blocker; Ki: 0.7 nM (mouse μ), 1.9 nM (δ), 5.7 nM (κ).
Formula:C₃₀H₃₃ClN₂O₇S
Color and Shape:Solid
Molecular weight:601.11
Ref: TM-T41184
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PROTAC ERα Y537S degrader-1
CAS:
- 2667598-05-0
PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group.
Formula:C₄₆H₄₉N₅O₆
Color and Shape:Solid
Molecular weight:767.91
Ref: TM-T74375
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Azilsartan Medoxomil Potassium
CAS:
- 863031-24-7
Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
Formula:C₃₀H₂₃N₄O₈·K
Purity:98.72%
Color and Shape:Solid
Molecular weight:606.62
Ref: TM-T0481
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Dexamethasone cipecilate
CAS:
- 132245-57-9
Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid.
Formula:C₃₃H₄₃FO₇
Purity:98%
Color and Shape:Solid
Molecular weight:570.69
Ref: TM-T27153
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Orphanin FQ(1-11)
CAS:
- 178249-41-7
Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.
Formula:C₄₉H₇₅N₁₅O₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:1098.2
Ref: TM-TP1882
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PROTAC ER Degrader-4
CAS:
- 2361114-15-8
PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).
Formula:C₅₃H₆₇F₃N₆O₈S
Purity:98%
Color and Shape:Solid
Molecular weight:1005.2
Ref: TM-T13839
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NPFF1-R antagonist 1
NPFF1-R antagonist 1 (compound 8b) is a piperidine analog and an effective neuropeptide FF (NPFF) receptor antagonist. It exhibits 15-fold selectivity for the NPFF1-R subtype, with Ki values of 211 nM and 3270 nM for NPFF1-R and NPFF2-R, respectively.
Formula:C₃₇H₄₄N₄O
Molecular weight:560.35151
Ref: TM-T209569
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Teriparatide
CAS:
- 52232-67-4
Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).
Formula:C₁₈₁H₂₉₁N₅₅O₅₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:4117.72
Ref: TM-T13128
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ERRγ agonist-2
CAS:
- 324022-01-7
ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a K d value of 6.5 μM.
Formula:C₂₇H₂₁N₅O₂
Color and Shape:Solid
Molecular weight:447.49
Ref: TM-T74840
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DP50
DP50 is a bifunctional compound containing both an opioid receptor agonist (MOP) and a neuropeptide FF receptor (NPFFR) antagonist. It can be utilized in studies related to analgesia.
Formula:C₅₈H₇₂N₈O₇
Molecular weight:992.5524
Ref: TM-TP3590
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PIPE-3297
PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.
Formula:C₂₃H₃₀N₂O
Molecular weight:350.23581
Ref: TM-T209195
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[Orn8]-Urotensin II acetate
[Orn8]-Urotensin II acetate is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.
Formula:C₆₅H₈₇N₁₃O₂₀S₂
Purity:98.63%
Color and Shape:Solid
Molecular weight:1434.59
Ref: TM-T37527L
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BigLEN(mouse)
CAS:
- 501036-69-7
GPR171 agonist from ProSAAS controls mouse appetite, reduces glutamate in paraventricular neurons via G protein.
Formula:C₇₈H₁₃₀N₂₄O₂₂
Purity:98%
Color and Shape:Solid
Molecular weight:1756.03
Ref: TM-TP2073
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ODM-204
CAS:
- 1642818-64-1
ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme(IC50s of 80 nM and 22 nM, respectively).
Formula:C₂₀H₂₁F₃N₄
Purity:98%
Color and Shape:Solid
Molecular weight:374.40
Ref: TM-T12289
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BWA-6047
BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.
Formula:C₄₂H₄₆ClN₅O₇
Color and Shape:Solid
Molecular weight:767.30858
Ref: TM-T207136
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MT-7716 hydrochloride
CAS:
- 1215859-93-0
MT-7716 hydrochloride is a selective agonist of non-peptide nociceptin receptor (NOP)
Formula:C₂₇H₂₉ClN₄O₂
Purity:98%
Color and Shape:Solid
Molecular weight:477
Ref: TM-T12120
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Myrciacetin
CAS:
- 203734-35-4
Myrciacetin from Rhododendron inhibits rat aldose reductase with IC50 of 13 μM.
Formula:C₁₇H₁₆O₆
Color and Shape:Solid
Molecular weight:316.309
Ref: TM-T39435
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Zankiren
CAS:
- 138742-43-5
Zankiren is a renin inhibitor. Zankiren can reduce blood pressure, plasma renin activity, and angiotension II.
Formula:C₃₅H₅₅N₅O₆S₂
Color and Shape:Solid
Molecular weight:705.97
Ref: TM-T29204
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11-Ketodihydrotestosterone
CAS:
- 32694-37-4
11-Ketodihydrotestosterone is a metabolite of 11β-Hydroxyandrostenedione. It is an active androgen and is also a potent androgen receptor (AR) agonist (Ki: 20.4 nM, EC50: 1.35 nM for human AR).
Formula:C₁₉H₂₈O₃
Color and Shape:Solid
Molecular weight:304.42
Ref: TM-T10041
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Epi-Cryptoacetalide
Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054.
Formula:C₁₈H₂₂O₃
Color and Shape:Solid
Molecular weight:286.371
Ref: TM-T126054
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Handle region peptide, rat
CAS:
- 749227-53-0
Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.
Formula:C₅₄H₁₀₁N₁₅O₁₂S
Purity:98%
Color and Shape:Solid
Molecular weight:1184.54
Ref: TM-TP1761
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LY301875
CAS:
- 154668-27-6
LY301875 is an antagonist of nonpeptide angiotensin receptor.
Formula:C₃₁H₃₆N₄O₁₀S
Color and Shape:Solid
Molecular weight:656.70
Ref: TM-T27940
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Koreanoside E
CAS:
- 1804014-67-2
Koreanoside E is a useful organic compound for research related to life sciences. The catalog number is T125538 and the CAS number is 1804014-67-2.
Formula:C₂₇H₃₀O₁₁
Color and Shape:Solid
Molecular weight:530.526
Ref: TM-T125538
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(S,S)-J-113397
CAS:
- 256640-46-7
(S,S)-J-113397 is an isomer of J-113397 . J-113397 is an Opioid Receptor antagonist [1] .
Formula:C₂₄H₃₇N₃O₂
Color and Shape:Solid
Molecular weight:399.57
Ref: TM-T73802
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(rel)-PROTAC ERRα Degrader-1
(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1, which is an estrogen-related receptor alpha (ERRa) degrader.
Formula:C₅₄H₄₉Cl₂F₆N₇O₈
Purity:98%
Color and Shape:Solid
Molecular weight:1108.91
Ref: TM-T18651
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NR-V04
CAS:
- 2766608-52-8
NR-V04 is a PROTAC degrader targeting NR4A1.
Formula:C₆₂H₈₇N₅O₁₁S
Color and Shape:Solid
Molecular weight:1110.45
Ref: TM-T201102
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PROTAC ER Degrader-14
CAS:
- 2504911-73-1
PROTAC ER Degrader-14 (compound 86) is a PROTAC-type estrogen receptor/ERR degrader. It comprises an E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide, a PROTAC linker (black part) N-Boc-piperazine, and a target protein ligand (red part) ER ligand-6. The combination of the E3 ligase and linker forms tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate.
Formula:C₄₄H₄₆FN₅O₅
Color and Shape:Solid
Molecular weight:743.865
Ref: TM-T204554
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Antidiabetic agent 15
Antidiabetic agent 15 (compound 1B15) acts as a dual inhibitor of AT1R and NEP, reducing oxidative stress and restoring mitochondrial membrane potential.
Formula:C₂₆H₂₃NO₅
Color and Shape:Solid
Molecular weight:429.15762
Ref: TM-T207568
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Bradykinin potentiator-5
CAS:
- 30505-63-6
Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.
Formula:C₃₀H₄₁N₇O₇
Purity:98%
Color and Shape:Solid
Molecular weight:611.69
Ref: TM-T25173
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SNIPER(ER)-87
CAS:
- 2222354-91-6
SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (
Formula:C₅₉H₇₃N₅O₁₀S
Purity:98%
Color and Shape:Solid
Molecular weight:1044.32
Ref: TM-T18697
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KOR agonist 5
KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).
Formula:C₃₈H₃₈N₂O₅
Color and Shape:Solid
Molecular weight:602.72
Ref: TM-T205351
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THR-β agonist 8
CAS:
- 2832859-77-3
THR-β agonist 8 (Compound 1) is an orally active agonist for both TRα and TRβ. It holds potential for research into thyroid hormone-related diseases.
Formula:C₁₉H₁₂Cl₂N₄O₄
Color and Shape:Solid
Molecular weight:431.23
Ref: TM-T203424
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ER degrader 4
CAS:
- 2913192-39-7
ER degrader 4, a selective and orally active compound, effectively degrades estrogen receptors and exhibits anti-tumor activity [1].
Formula:C₂₆H₁₉FO₄S
Color and Shape:Solid
Molecular weight:446.49
Ref: TM-T74856
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ZINC05925939
ZINC05925939 is an estrogen receptor β (ESR2) inhibitor used in breast cancer research.
Formula:C₁₇H₁₇NO₂
Color and Shape:Solid
Molecular weight:267.32
Ref: TM-T89848
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RLA-4842
RLA-4842: iron-based anti-androgen; inhibits mCRPC cell proliferation.
Formula:C₄₂H₄₆F₃N₅O₈S
Color and Shape:Solid
Molecular weight:837.9
Ref: TM-T75057
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Nurr1 agonist 12
Nurr1 agonist 12 (Compound 37) acts as an agonist of the nuclear receptor-related protein 1 (Nurr1), enhancing its transcriptional activity with an EC50 of 0.06 μM. It stimulates human response elements NBRE, NurRE, and DR5 with EC50 values of 0.07 μM, 0.027 μM, and 0.014 μM, respectively. Additionally, Nurr1 agonist 12 induces the expression of neurotrophic genes regulated by Nurr1, such as tyrosine hydroxylase (TH), SOD1/2, BDNF, Sestrin 3, and BIRC5 (Survivin). The compound also demonstrates neuroprotective effects against neurotoxicity caused by Paraquat.
Formula:C₁₈H₁₂ClN₃O
Color and Shape:Solid
Molecular weight:321.76
Ref: TM-T206188
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GPR88 agonist 2
GPR88 agonist 2 (compound 53) serves as a potent, brain-penetrant agonist of GPR88, exhibiting an EC50 of 14 µM in the GPR88 cAMP functional assay [1].
Color and Shape:Odour Solid
Ref: TM-T79902