Endocrinology/Hormones
Endocrinology/hormone inhibitors are compounds that block the action of hormones or interfere with hormone signaling pathways. These inhibitors are essential for studying the regulation of endocrine systems and for developing treatments for hormone-related diseases, such as diabetes, thyroid disorders, and hormone-dependent cancers. By modulating hormone activity, these inhibitors can help elucidate the complex interactions within the endocrine system. At CymitQuimica, we offer a wide range of high-quality endocrinology/hormone inhibitors to support your research in endocrinology, pharmacology, and medical sciences.
Subcategories of "Endocrinology/Hormones"
- Androgen Receptor(207 products)
- Annexin A(11 products)
- Aromatase(20 products)
- Estrogen/progestogen Receptor(49 products)
- GPR(1 products)
- Glucocorticoid Receptor(153 products)
- LHRH(1 products)
- Opioid Receptor(296 products)
- Prostaglandin Receptor(119 products)
- RAAS(86 products)
- Reductase(52 products)
- Somatostatin(46 products)
- Thyroid hormone receptor(THR)(26 products)
- Vasopressin Receptor(44 products)
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Found 3178 products of "Endocrinology/Hormones"
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2-Ethylhexyl trans-4-methoxycinnamate
CAS:<p>2-Ethylhexyl trans-4-methoxycinnamate is a sunscreen agent.</p>Formula:C18H26O3Purity:98.92%Color and Shape:Pale Yellow LiquidMolecular weight:290.4Urotensin II, mouse
CAS:<p>UTS2 is a human gene, alias U-II, on chromosome 1p36.23, codes for Urotensin-II, a potent vasoconstrictor. Formula: C64H85N13O18S2, Molar mass: 1388.6 g/mol.</p>Formula:C76H100N18O19S2Purity:98%Color and Shape:SolidMolecular weight:1633.86TRV056
CAS:<p>TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.</p>Formula:C52H74N14O13Color and Shape:SolidMolecular weight:1103.249Angiotensin amide
CAS:<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Formula:C49H70N14O11Purity:98%Color and Shape:SolidMolecular weight:1031.17AKR1B10-IN-1
CAS:<p>AKR1B10-IN-1: potent AKR1B10 inhibitor, IC50 3.5 nM; hinders lung cancer cell growth, spread, and Cisplatin resistance.</p>Formula:C19H16FNO4Color and Shape:SolidMolecular weight:341.338UFP-101
CAS:<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Formula:C82H138N32O21Purity:98%Color and Shape:SolidMolecular weight:1908.194'-hydroxy Tamoxifen
CAS:<p>It is a metabolite of tamoxifen and an estrogen receptor modulator.</p>Formula:C26H29NO2Purity:98%Color and Shape:SolidMolecular weight:387.511α-Hydroxy-3-epi-vitamin D3
CAS:<p>1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].</p>Formula:C27H44O2Color and Shape:SolidMolecular weight:400.647PROTAC AR Degrader-4 TFA
<p>PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.</p>Formula:C45H68F3N3O11Color and Shape:SolidMolecular weight:884.03U-54494A hydrochloride
CAS:<p>U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.</p>Formula:C18H25Cl3N2OColor and Shape:SolidMolecular weight:391.76PROTAC ERRα Degrader-2
CAS:<p>PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group.</p>Formula:C57H55Cl2F6N7O8Purity:98%Color and Shape:SolidMolecular weight:1150.99Ac-RYYRIK-NH2
CAS:<p>NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.</p>Formula:C44H70N14O9Purity:98%Color and Shape:SolidMolecular weight:939.12Prepro-TRH-(160-169)
CAS:<p>Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.</p>Formula:C54H75N11O18SColor and Shape:SolidMolecular weight:1198.3PROTAC ER Degrader-15
<p>PROTAC ER Degrader-15 (Compound 40) is an orally active estrogen receptor (ER) degrader with anticancer properties, suitable for breast cancer research.</p>Formula:C47H47F4N5O5Color and Shape:SolidMolecular weight:837.9Antitumor agent-195
<p>Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.</p>Formula:C22H22N2O4Color and Shape:SolidMolecular weight:378.42Aliskiren D6 Hydrochloride
CAS:<p>Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).</p>Formula:C30H54ClN3O6Purity:98%Color and Shape:SolidMolecular weight:594.26[Sar1, Ile8]-Angiotensin II acetate
<p>'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.</p>Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2PL-017
CAS:<p>μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.</p>Formula:C29H37N5O5Purity:98%Color and Shape:SolidMolecular weight:535.64PROTAC ERα Degrader-7
CAS:<p>PROTAC ERα Degrader-7 (Compound i-320) is a powerful PROTAC degrader targeting the estrogen receptor alpha (ERα), exhibiting a DC50 of 0.000006 µM. This compound consists of a cereblon-binding segment, LBM, connected to ERBM, an ERα-binding ligand that includes a benzofused partially saturated 6-membered carbocyclic or heterocyclic ring [1].</p>Formula:C46H49F2N5O4Color and Shape:SolidMolecular weight:773.91Melanin Concentrating Hormone, salmon TFA
<p>MCH (salmon) TFA is a 19-amino-acid neuropeptide affecting appetite, energy, sleep, and heart health via GPCR SLC-1/GPR24 and MCHR2.</p>Formula:C91H140F3N27O26S4Color and Shape:SolidMolecular weight:2213.5BigLEN(mouse)
CAS:<p>GPR171 agonist from ProSAAS controls mouse appetite, reduces glutamate in paraventricular neurons via G protein.</p>Formula:C78H130N24O22Purity:98%Color and Shape:SolidMolecular weight:1756.03(rel)-PROTAC ERRα Degrader-1
<p>(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1, which is an estrogen-related receptor alpha (ERRa) degrader.</p>Formula:C54H49Cl2F6N7O8Purity:98%Color and Shape:SolidMolecular weight:1108.91PROTAC ERα Degrader-8
CAS:<p>PROTAC ERα Degrader-8 (compound ii-56), a highly potent degrader of Erα, achieves a DC50 of just 0.000006 μM in MCF7 cells [1].</p>Formula:C47H51N5O4Color and Shape:SolidMolecular weight:749.94PROTAC ER Degrader-4
CAS:<p>PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).</p>Formula:C53H67F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:1005.2[Arg14,Lys15]Nociceptin
CAS:<p>Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.</p>Formula:C82H137N31O22Purity:98%Color and Shape:SolidMolecular weight:1909.18Herkinorin
CAS:<p>Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.</p>Formula:C28H30O8Color and Shape:SolidMolecular weight:494.53Estrone-N-O-C1-amido
CAS:<p>Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα).</p>Formula:C20H26N2O3Purity:98%Color and Shape:SolidMolecular weight:342.439DAMGO (TFA)
CAS:<p>DAMGO is a selective peptide agonist of the µ-opioid receptor .</p>Formula:C28H36F3N5O8Purity:98%Color and Shape:SolidMolecular weight:627.61OT-R antagonist 2
CAS:<p>OT-R antagonist 2 is a nonpeptide low molecular weight antagonist of OT-R .</p>Formula:C28H29N3O4Purity:98%Color and Shape:SolidMolecular weight:471.55BI 653048
CAS:<p>BI 653048 is a selective and orally active agonist of nonsteroidal glucocorticoid (IC50: 55 nM). BI 653048 is also an HCV NS3 protease inhibitor.</p>Formula:C23H25F4N3O4SPurity:98%Color and Shape:SolidMolecular weight:515.523-epi-25-hydroxy Vitamin D3
CAS:<p>3-epi-25-hydroxy Vitamin D3 lowers serum PTH in male weanling rats at 0.5 and 1 IU/g doses; doesn't affect females.</p>Formula:C27H44O2Color and Shape:SolidMolecular weight:400.64GNE-274
CAS:<p>GNE-274, akin to GDC-0927 but non-degrading, is a partial ER agonist in breast cancer, enhancing chromatin at ER sites, inhibiting ER-LBD.</p>Formula:C29H31NO4Color and Shape:SolidMolecular weight:457.57Zavacorilant
CAS:<p>Zavacorilant is capable of modulating glucocorticoid receptor (GR).</p>Formula:C25H26FN7O3S2Color and Shape:SolidMolecular weight:555.65NH-3
CAS:<p>NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.</p>Formula:C28H27NO6Purity:97.79% - 99.40%Color and Shape:SolidMolecular weight:473.52Naldemedine
CAS:<p>Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.</p>Formula:C32H34N4O6Color and Shape:SolidMolecular weight:570.64Cgp 38560
CAS:<p>CGP 38560 is a potent renin inhibitor.</p>Formula:C40H67N5O9S2Color and Shape:SolidMolecular weight:826.12Dipropyl phthalate
CAS:<p>Dipropyl phthalate is a weak androgen receptor inhibitor, and can be used in biochemical experiments and drug synthesis.</p>Formula:C14H18O4Purity:98.62%Color and Shape:SolidMolecular weight:250.29Methylpiperidino pyrazole
CAS:<p>Methylpiperidino pyrazole is an ERα inhibitor and can prevent the BPS-induced Rb phosphorylation and cell cycle progression.</p>Formula:C29H31N3O3Purity:98.84%Color and Shape:SolidMolecular weight:469.57ST-CY14
<p>ST-CY14 is an inhibitor of the Nur77-PPARγ interaction with an EC50 of 3.15 μM. It binds to Nur77 (Kd=32 nM) to prevent its ubiquitination and degradation by PPARγ, reducing fatty acid uptake and mitochondrial respiration, and inhibiting the transcription of CD36 and FABP4. ST-CY14 suppresses proliferation and migration of MCF7 and MDA-MB-231 cancer cells and impedes tumor growth and bone metastasis in mouse models.</p>Formula:C139H237N57O31S2Color and Shape:SolidMolecular weight:3266.86OBHSA
CAS:<p>OBHSA（Oxabicycloheptane sulfonamide） is a novel selective estrogen receptor depressant (SERD) that can be used to study breast cancer.</p>Formula:C27H24F3NO6SPurity:98%Color and Shape:SolidMolecular weight:547.543-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Color and Shape:Odour SolidDDHF20
<p>DDHF20 is an inhibitor of Staphylococcus aureus, specifically targeting and inhibiting its thioredoxin reductase (TrxR) by acting as a competitive inhibitor at the NADPH binding site. DDHF20 shows potential for research in combating infections related to Staphylococcus aureus.</p>Formula:C34H28O4Color and Shape:SolidMolecular weight:500.58Teriparatide
CAS:<p>Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).</p>Formula:C181H291N55O51S2Purity:98%Color and Shape:SolidMolecular weight:4117.72Axelopran
CAS:<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Formula:C26H39N3O4Color and Shape:SolidMolecular weight:457.614,4'-(Cyclohexylidenemethylene)diphenol
CAS:<p>4,4'-(Cyclohexylidenemethylene)diphenol (Compound 2) is a symmetrical cyclic non-steroidal estrogen. It exhibits high binding affinity to estrogen receptors ERα and ERβ.</p>Formula:C19H20O2Color and Shape:SolidMolecular weight:280.36Neuropeptide AF (human)
CAS:<p>Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.</p>Formula:C90H132N26O25Purity:98%Color and Shape:SolidMolecular weight:1978.17PTP1B/AKR1B1-IN-1
<p>PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s</p>Formula:C22H21NO4S2Purity:98%Color and Shape:SolidMolecular weight:427.54ET receptor antagonist 2
<p>ET Receptor Antagonist 2 (Compound 16j) is an orally active ET receptor antagonist with an IC50 of 0.22 nM, suitable for pulmonary arterial hypertension (PAH)</p>Formula:C22H25N5O5SPurity:98%Color and Shape:SolidMolecular weight:471.53(E)-4-Hydroxytamoxifen
CAS:<p>(E)-4-Hydroxytamoxifen is a less active isomer of (Z)-4-hydroxytamoxifen and also is an estrogen receptor modulator.</p>Formula:C26H29NO2Color and Shape:SolidMolecular weight:387.51SCO-267
CAS:<p>SCO-267 is a full agonist of GPR40/FFAR1， stimulating insulin secretion and GLP-1 release in diabetic rats, improving glucose tolerance,type 2 diabetes.</p>Formula:C36H46N4O5Purity:99.89%Color and Shape:SolidMolecular weight:614.77
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