RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Found 89 products of "RAAS"
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Pomisartan 2HCl
Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.
Formula:C31H32Cl2N4O2Purity:99.88%Color and Shape:SoildMolecular weight:563.52Zansecimab
CAS:Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.Purity:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.23 kDaLosartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFormula:C22H22ClKN6OPurity:99.9% - >99.99%Color and Shape:White To Off-White Crystalline PowderMolecular weight:461.01Olmesartan Medoxomil
CAS:Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.Formula:C29H30N6O6Purity:99.89% - 99.9%Color and Shape:White To Off-White Crystalline PowderMolecular weight:558.59Ref: TM-T1518
5mg34.00€10mg50.00€25mg57.00€50mg63.00€100mg93.00€200mg137.00€500mg260.00€1mL*10mM (DMSO)55.00€Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Formula:C22H23ClN6OPurity:99.48% - >99.99%Color and Shape:Off White Solid PowderMolecular weight:422.91A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Formula:C39H60N12O11Purity:98%Color and Shape:SolidMolecular weight:872.97TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Formula:C44H61N9O11Purity:99.84%Color and Shape:SolidMolecular weight:892.01Ref: TM-T40220L
1mg109.00€2mg154.00€5mg235.00€10mg349.00€25mg532.00€50mg745.00€100mg999.00€200mg1,333.00€1mL*10mM (DMSO)389.00€[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Formula:C46H73N13O10Purity:98%Color and Shape:SolidMolecular weight:968.15[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2Ref: TM-T7575L1
2mg34.00€5mg46.00€10mg60.00€25mg119.00€50mg192.00€100mg289.00€200mg415.00€1mL*10mM (DMSO)90.00€Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formula:C54H101N15O12SPurity:98%Color and Shape:SolidMolecular weight:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formula:C30H23N4O8·KPurity:99.99%Color and Shape:SolidMolecular weight:606.62[Sar1, Ile8]-Angiotensin II TFA
[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.Formula:C48H74F3N13O12Purity:98%Color and Shape:SolidMolecular weight:1082.18Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Formula:C26H38F3N7O10Purity:98%Color and Shape:SolidMolecular weight:665.62Angiotensin II 5-valine
CAS:ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.Formula:C49H69N13O12Purity:98%Color and Shape:SolidMolecular weight:N/AAngiotensin amide
CAS:Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.Formula:C49H70N14O11Purity:98%Color and Shape:SolidMolecular weight:1031.17Aliskiren D6 Hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Formula:C30H54ClN3O6Purity:98%Color and Shape:SolidMolecular weight:594.26Brain Natriuretic Peptide (1-32), rat
CAS:Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.Formula:C146H239N47O44S3Purity:98%Color and Shape:SolidMolecular weight:3452.94Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFormula:C26H36N6O5Purity:98%Color and Shape:SolidMolecular weight:512.6Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formula:C24H37N7O8Purity:98%Color and Shape:SolidMolecular weight:551.59Saralasin
CAS:Competitive non-selective angiotensin II antagonist.Formula:C42H65N13O10Purity:98%Color and Shape:PowderMolecular weight:912C-Type Natriuretic Peptide (1-53), human
CAS:CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.Formula:C251H417N81O71S3Purity:98%Color and Shape:SolidMolecular weight:5801.77TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Formula:C52H74N14O13Color and Shape:SolidMolecular weight:1103.249Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Formula:C42H64N12O11Color and Shape:SolidMolecular weight:913.03Eprosartan
CAS:Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.Formula:C23H24N2O4SPurity:99.99%Color and Shape:SolidMolecular weight:424.51PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.
Color and Shape:Odour SolidTetrahydro Aldosterone
CAS:Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.Formula:C21H32O5Color and Shape:SolidMolecular weight:364.48Angiotensin II (3-8), human TFA
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.Formula:C42H55F3N8O10Purity:98%Color and Shape:SolidMolecular weight:888.93Renin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formula:C90H120N22O16SColor and Shape:SolidMolecular weight:1798.15BIBS 39
CAS:BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.Formula:C32H36N4O3Purity:99.28%Color and Shape:SolidMolecular weight:524.65Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg
Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg is a fluorescent renin substrate based on the N-terminal tetrapeptide sequence of human angiotensinogen (hTDP).Formula:C129H179N37O24SMolecular weight:2662.36444Chymase
CAS:Chymase is a proteolytic enzyme predominantly found in mast cells (MC), fibroblasts, and vascular endothelial cells. It is released into the extracellular matrix in response to inflammatory signals, tissue damage, and cellular stress. Chymase also plays a role in the generation of angiotensin II (Ang II), making it significant for cardiovascular disease research.Nesvacumab
CAS:Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.Purity:98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.84 kDaAlunacedase alfa
CAS:Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.Purity:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Color and Shape:LiquidMolecular weight:85.03 kDaValsartan Methyl Ester
CAS:Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
Formula:C25H31N5O3Purity:99.54%Color and Shape:SolidMolecular weight:449.55CGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Formula:C54H73N13O13Purity:99.06% - 99.92%Color and Shape:SoildMolecular weight:1112.24Ref: TM-T14939L
1mg93.00€5mg279.00€10mg403.00€25mg623.00€50mg837.00€100mg1,108.00€200mg1,504.00€1mL*10mM (DMSO)622.00€Azilsartan-d5
CAS:Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.Formula:C25H20N4O5Purity:98%Color and Shape:SolidMolecular weight:461.48Valsartan-d9
CAS:Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.Formula:C24H29N5O3Purity:98%Color and Shape:SolidMolecular weight:444.57Olmesartan-d4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Formula:C24H26N6O3Purity:98%Color and Shape:SolidMolecular weight:450.53Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Formula:C22H21ClN6O2Purity:98%Color and Shape:SolidMolecular weight:440.92Angiotensin II (3-8), human
CAS:Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.Color and Shape:SolidAngiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Formula:C78H125N25O23Color and Shape:SolidMolecular weight:1780.98Candesartan-d4
CAS:Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.Formula:C24H20N6O3Purity:98%Color and Shape:SolidMolecular weight:444.48PD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Formula:C35H34F6N4O7Purity:98%Color and Shape:SolidMolecular weight:736.66Angiotensin I/II (1-6)
CAS:Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.Formula:C36H55N11O10Purity:99.44%Color and Shape:SolidMolecular weight:801.89Olmesartan
CAS:Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.Formula:C24H26N6O3Purity:91.89% - 99.81%Color and Shape:White To Beige Solid SolidMolecular weight:446.50Angiotensin III, human, mouse
CAS:Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).Formula:C46H66N12O9Purity:98.44%Color and Shape:SolidMolecular weight:931.09Angiotensin II 5-valine TFA
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.Formula:C51H70F3N13O14Purity:99.69%Color and Shape:SolidMolecular weight:1146.18H-Val-Pro-Pro-OH
CAS:H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).Formula:C15H25N3O4Purity:98.23%Color and Shape:SolidMolecular weight:311.38Olodanrigan
CAS:Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.Formula:C32H29NO5Purity:98.33%Color and Shape:SolidMolecular weight:507.58Tasosartan
CAS:Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).Formula:C23H21N7OPurity:98.2% - 98.9%Color and Shape:SolidMolecular weight:411.46Ref: TM-T7797
1mg52.00€2mg77.00€5mg113.00€10mg177.00€25mg299.00€50mg447.00€100mg623.00€1mL*10mM (DMSO)124.00€
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