RAAS
RAAS (Renin-Angiotensin-Aldosterone System) inhibitors are compounds that target the RAAS pathway, which is primarily known for its role in regulating blood pressure and fluid balance but also influences angiogenesis. The RAAS pathway can contribute to the development of new blood vessels in tumors, thus supporting their growth. Inhibiting components of the RAAS can therefore have anti-angiogenic effects, making these inhibitors valuable in the treatment of certain cancers and vascular disorders. At CymitQuimica, we offer a range of high-quality RAAS inhibitors to support your research in cardiovascular biology, oncology, and angiogenesis.
Found 86 products of "RAAS"
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Telmisartan
CAS:<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Formula:C33H30N4O2Purity:99.88% - 99.97%Color and Shape:White Or Off White Crystalline PowderMolecular weight:514.62Losartan
CAS:<p>Losartan (DuP-753) is an angiotensin II receptor antagonist.</p>Formula:C22H23ClN6OPurity:99.48% - >99.99%Color and Shape:Off White Solid PowderMolecular weight:422.91Losartan potassium
CAS:<p>Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the</p>Formula:C22H22ClKN6OPurity:99.9% - >99.99%Color and Shape:White To Off-White Crystalline PowderMolecular weight:461.01Zansecimab
CAS:<p>Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.</p>Purity:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:LiquidPomisartan 2HCl
<p>Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.</p>Formula:C31H32Cl2N4O2Purity:99.88%Color and Shape:SoildMolecular weight:563.52Olmesartan Medoxomil
CAS:<p>Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.</p>Formula:C29H30N6O6Purity:99.89% - 99.9%Color and Shape:White To Off-White Crystalline PowderMolecular weight:558.59Angiotensin II (3-8), human TFA
<p>Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.</p>Formula:C42H55F3N8O10Purity:98%Color and Shape:SolidMolecular weight:888.93Tetrahydro Aldosterone
CAS:<p>Tetrahydro Aldosterone is a steroidal compound that inhibits the adrenal angiotensin II receptor, with an IC50 of 10 μM.</p>Formula:C21H32O5Color and Shape:SolidMolecular weight:364.48PRO20
<p>PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.</p>Color and Shape:Odour SolidTRV055 acetate
<p>TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.</p>Formula:C44H61N9O11Purity:99.84%Color and Shape:SolidMolecular weight:892.01Alunacedase alfa
CAS:<p>Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.</p>Purity:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Color and Shape:LiquidEprosartan
CAS:<p>Eprosartan is a selective AT1 receptor blocker with IC50s of 9.2 nM (rat) and 3.9 nM (human), used for hypertension.</p>Formula:C23H24N2O4SPurity:>99.99%Color and Shape:SolidMolecular weight:424.51Aclerastide
CAS:<p>Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.</p>Formula:C42H64N12O11Color and Shape:SolidMolecular weight:913.03TRV056
CAS:<p>TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.</p>Formula:C52H74N14O13Color and Shape:SolidMolecular weight:1103.249Aliskiren D6 Hydrochloride
CAS:<p>Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).</p>Formula:C30H54ClN3O6Purity:98%Color and Shape:SolidMolecular weight:594.26C-Type Natriuretic Peptide (1-53), human
CAS:<p>CNP, from natriuretic family, first in pigs, now in other species, processes into CNP-22/CNP-53, similar to ANP/BNP, with varying potencies.</p>Formula:C251H417N81O71S3Purity:98%Color and Shape:SolidMolecular weight:5801.77Saralasin
CAS:<p>Competitive non-selective angiotensin II antagonist.</p>Formula:C42H65N13O10Purity:98%Color and Shape:PowderMolecular weight:912[Sar1, Ile8]-Angiotensin II acetate
<p>'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.</p>Formula:C48H77N13O12Purity:99.36%Color and Shape:SolidMolecular weight:1028.2Handle region peptide, rat
CAS:<p>Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.</p>Formula:C54H101N15O12SPurity:98%Color and Shape:SolidMolecular weight:1184.54Azilsartan Medoxomil Potassium
CAS:<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Formula:C30H23N4O8·KPurity:98.72%Color and Shape:SolidMolecular weight:606.62[Sar1, Ile8]-Angiotensin II TFA
<p>[Sar1,Ile8]-Angiotensin II (TFA) contracts arteries and affects cell growth in vascular muscle.</p>Formula:C48H74F3N13O12Purity:98%Color and Shape:SolidMolecular weight:1082.18CGP-42112 acetate
<p>CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.</p>Formula:C54H73N13O13Purity:99.06% - 99.92%Color and Shape:SoildMolecular weight:1112.24Angiotensin II (1-4), human
CAS:<p>Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.</p>Formula:C24H37N7O8Purity:98%Color and Shape:SolidMolecular weight:551.59Angiotensin II (1-4), human TFA
<p>Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.</p>Formula:C26H38F3N7O10Purity:98%Color and Shape:SolidMolecular weight:665.62Angiotensin II (5-8), human
CAS:<p>Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II</p>Formula:C26H36N6O5Purity:98%Color and Shape:SolidMolecular weight:512.6Brain Natriuretic Peptide (1-32), rat
CAS:<p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>Formula:C146H239N47O44S3Purity:98%Color and Shape:SolidMolecular weight:3452.94Valsartan Methyl Ester
CAS:<p>Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.</p>Formula:C25H31N5O3Purity:99.54%Color and Shape:SolidMolecular weight:449.55[Sar1, Ile8]-Angiotensin II
CAS:<p>[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.</p>Formula:C46H73N13O10Purity:98%Color and Shape:SolidMolecular weight:968.15Angiotensin amide
CAS:<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Formula:C49H70N14O11Purity:98%Color and Shape:SolidMolecular weight:1031.17Angiotensin II 5-valine
CAS:<p>ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.</p>Formula:C49H69N13O12Purity:98%Color and Shape:SolidMolecular weight:N/ANesvacumab
CAS:<p>Nesvacumab (REGN910) is a fully human monoclonal antibody targeting Angiopoietin 2 (Ang2), which can be used for studying advanced solid tumors.</p>Purity:98.7% (SDS-PAGE); 95.7% (SEC-HPLC) - 99.11% (SEC-HPLC)Color and Shape:LiquidA 779
CAS:<p>A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.</p>Formula:C39H60N12O11Purity:98%Color and Shape:SolidMolecular weight:872.97BIBS 39
CAS:<p>BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.</p>Formula:C32H36N4O3Purity:99.28%Color and Shape:SolidMolecular weight:524.65Valsartan-d9
CAS:<p>Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.</p>Formula:C24H29N5O3Purity:98%Color and Shape:SolidMolecular weight:444.57Losartan (D4 Carboxylic Acid)
CAS:<p>Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.</p>Formula:C22H21ClN6O2Purity:98%Color and Shape:SolidMolecular weight:440.92Azilsartan-d5
CAS:<p>Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.</p>Formula:C25H20N4O5Purity:98%Color and Shape:SolidMolecular weight:461.48PD 123319 ditrifluoroacetate
CAS:<p>PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.</p>Formula:C35H34F6N4O7Purity:98%Color and Shape:SolidMolecular weight:736.66Olmesartan-d4
CAS:<p>Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.</p>Formula:C24H26N6O3Purity:98%Color and Shape:SolidMolecular weight:450.53Candesartan-d4
CAS:<p>Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.</p>Formula:C24H20N6O3Purity:98%Color and Shape:SolidMolecular weight:444.48Angiotensin II (3-8), human
CAS:<p>Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.</p>Color and Shape:SolidAngiotensin 1/2 (5-7) acetate
<p>Angiotensin 1/2 (5-7) acetate: a dipsogenic hormone peptide, sequence H2N-Ile-His-Pro-OH, from liver-produced angiotensinogen.</p>Formula:C19H31N5O6Purity:99.13%Color and Shape:SolidMolecular weight:425.49VTP-27999 TFA
CAS:<p>VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).</p>Formula:C28H42ClF3N4O7Purity:98.84%Color and Shape:SolidMolecular weight:639.1Alamandine TFA
<p>Alamandine TFA, a RAS peptide, binds MrgD receptors, has anti-hypertensive effects, and protects heart and kidneys.</p>Formula:C42H63F3N12O11Purity:99.62%Color and Shape:SoildMolecular weight:969.02Azilsartan Medoxomil
CAS:<p>Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults</p>Formula:C30H24N4O8Purity:99.83%Color and Shape:SolidMolecular weight:568.53A 779 TFA(159432-28-7 free base)
<p>A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.</p>Formula:C41H61F3N12O13Purity:99.55%Color and Shape:SolidMolecular weight:987.01Novokinin acetate
<p>Novokinin acetate binds AT2 receptor (Ki=7 nM); antihypertensive effect blocked by PD123319.</p>Formula:C41H65N11O9Purity:99.37%Color and Shape:SoildMolecular weight:856.02H-Val-Pro-Pro-OH
CAS:<p>H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).</p>Formula:C15H25N3O4Purity:98.23%Color and Shape:SolidMolecular weight:311.38(Sar¹)-Angiotensin II acetate
<p>(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor.</p>Formula:C51H75N13O12Purity:99.89%Color and Shape:SoildMolecular weight:1062.22SSAA09E2
CAS:<p>SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-</p>Formula:C16H20N4O2Purity:99.41%Color and Shape:SolidMolecular weight:300.36Acein acetate
<p>ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.</p>Formula:C45H72N10O15Purity:99.43%Color and Shape:SolidMolecular weight:993.11
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