Hydroxylase
Hydroxylases are a class of enzymes that catalyze the hydroxylation of substrates, often adding hydroxyl groups (-OH) to specific positions within molecules. These enzymes are involved in a wide variety of biochemical pathways, including the synthesis of hormones, detoxification processes, and the metabolism of drugs. Hydroxylase inhibitors and activators are valuable tools in research on metabolic disorders, drug metabolism, and hormonal regulation. At CymitQuimica, we provide a selection of high-quality hydroxylase reagents to support your research in biochemistry, pharmacology, and metabolic regulation.
Found 36 products of "Hydroxylase"
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Fenclonine
CAS:Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H10ClNO2Purity:98.81% - >99.99%Color and Shape:Crystals From Methanol White SolidMolecular weight:199.63ACT-678689
CAS:ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].Formula:C23H22ClFN6O4S2Purity:99.46%Color and Shape:SolidMolecular weight:565.04Ref: TM-T14119
1mg107.00€5mg245.00€10mg371.00€25mg620.00€50mg858.00€100mg1,153.00€200mg1,549.00€1mL*10mM (DMSO)308.00€Telotristat ethyl
CAS:Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Formula:C27H26ClF3N6O3Purity:98% - 99.89%Color and Shape:White SolidMolecular weight:574.98p-Ethynylphenylalanine hydrochloride
CAS:p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Formula:C11H12ClNO2Purity:99.03%Color and Shape:SolidMolecular weight:225.67Butobendine
CAS:Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Formula:C32H48N2O10Color and Shape:SolidMolecular weight:620.73IOX2-NH2-1
CAS:IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.Formula:C19H17N3O5Purity:98.77% - 99.91%Color and Shape:SoildMolecular weight:367.36TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formula:C21H18N6O4SColor and Shape:SolidMolecular weight:450.47TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingColor and Shape:Odour SolidGSK180
CAS:GSK180 is a potent KMO inhibitor (IC50 ~6 nM) that modulates kynurenine metabolism for metabolic, neurological, and inflammatory research.Formula:C10H7Cl2NO4Color and Shape:SolidMolecular weight:276.07Cuprizone
CAS:Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.Formula:C14H22N4O2Purity:≥98%Color and Shape:SolidMolecular weight:278.35FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Formula:C12H9ClN2O4Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:280.66Ro 61-8048
CAS:Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Formula:C17H15N3O6S2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:421.45Ref: TM-T1896
2mg37.00€5mg54.00€10mg73.00€25mg114.00€50mg178.00€100mg284.00€200mg512.00€500mg822.00€1mL*10mM (DMSO)60.00€Telotristat
CAS:Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.Formula:C25H22ClF3N6O3Purity:99.70%Color and Shape:SolidMolecular weight:546.93Ref: TM-T21506
5mg46.00€10mg62.00€25mg119.00€50mg187.00€100mg304.00€200mg424.00€1mL*10mM (DMSO)52.00€p-Fluoro-L-phenylalanine
CAS:p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.Formula:C9H10FNO2Purity:99.63%Color and Shape:White To Off-White PowderMolecular weight:183.18Fenclonine hydrochloride
CAS:Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H11Cl2NO2Color and Shape:SolidMolecular weight:236.095Telotristat Etiprate
CAS:Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.Formula:C27H26ClF3N6O3·C9H9NO3Purity:99.21% - 99.83%Color and Shape:White SolidMolecular weight:754.15Ref: TM-T6044
2mg43.00€5mg63.00€10mg96.00€25mg142.00€50mg173.00€100mg309.00€500mg740.00€1mL*10mM (DMSO)80.00€Tetrahydropapaverine hydrochloride
CAS:Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.Formula:C20H26ClNO4Purity:99.08%Color and Shape:White Crystal PowderMolecular weight:379.878Mildronate
CAS:Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitineFormula:C6H14N2O2Purity:99.94%Color and Shape:White Crystalline PowderMolecular weight:146.19TETRAHYDROPIPERINE
CAS:Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.Formula:C17H23NO3Purity:98.04% - 99.61%Color and Shape:Off-White Low Melting Solid With Characteristic OdourMolecular weight:289.37Nepicastat
CAS:Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.Formula:C14H15F2N3SColor and Shape:SolidMolecular weight:295.35
