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Hydroxylase

Hydroxylase

Hydroxylases are a class of enzymes that catalyze the hydroxylation of substrates, often adding hydroxyl groups (-OH) to specific positions within molecules. These enzymes are involved in a wide variety of biochemical pathways, including the synthesis of hormones, detoxification processes, and the metabolism of drugs. Hydroxylase inhibitors and activators are valuable tools in research on metabolic disorders, drug metabolism, and hormonal regulation. At CymitQuimica, we provide a selection of high-quality hydroxylase reagents to support your research in biochemistry, pharmacology, and metabolic regulation.

Found 30 products of "Hydroxylase"

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  • p-Ethynylphenylalanine hydrochloride

    CAS:
    <p>p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].</p>
    Formula:C11H12ClNO2
    Purity:99.03%
    Color and Shape:Solid
    Molecular weight:225.67
  • Fenclonine

    CAS:
    <p>Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.</p>
    Formula:C9H10ClNO2
    Purity:98.81% - >99.99%
    Color and Shape:Crystals From Methanol White Solid
    Molecular weight:199.63
  • ACT-678689

    CAS:
    <p>ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].</p>
    Formula:C23H22ClFN6O4S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:565.04
  • Telotristat ethyl

    CAS:
    <p>Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.</p>
    Formula:C27H26ClF3N6O3
    Purity:98% - 99.89%
    Color and Shape:White Solid
    Molecular weight:574.98
  • TPT-004


    <p>TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuating</p>
    Color and Shape:Odour Solid
  • IOX2-NH2-1

    CAS:
    <p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>
    Formula:C19H17N3O5
    Purity:98.77% - 99.91%
    Color and Shape:Soild
    Molecular weight:367.36
  • TPH1-IN-1


    <p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>
    Formula:C21H18N6O4S
    Color and Shape:Solid
    Molecular weight:450.47
  • GSK180

    CAS:
    <p>GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.</p>
    Formula:C10H7Cl2NO4
    Color and Shape:Solid
    Molecular weight:276.07
  • Cuprizone

    CAS:
    <p>Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.</p>
    Formula:C14H22N4O2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:278.35
  • Nepicastat hydrochloride

    CAS:
    <p>Nepicastat hydrochloride (RS-25560-197 hydrochloride) is a selective, orally active, dopamine-beta-hydroxylase inhibitor that crosses the blood-brain barrier.</p>
    Formula:C14H15F2N3S·HCl
    Purity:98.35% - 99.74%
    Color and Shape:Solid
    Molecular weight:331.81
  • FG-2216

    CAS:
    <p>FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.</p>
    Formula:C12H9ClN2O4
    Purity:97.1% - >99.99%
    Color and Shape:Solid
    Molecular weight:280.66
  • Tetrahydropapaverine hydrochloride

    CAS:
    <p>Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.</p>
    Formula:C20H26ClNO4
    Purity:99.08%
    Color and Shape:White Crystal Powder
    Molecular weight:379.878
  • Telotristat

    CAS:
    <p>Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.</p>
    Formula:C25H22ClF3N6O3
    Purity:99.70%
    Color and Shape:Solid
    Molecular weight:546.93
  • Ro 61-8048

    CAS:
    <p>Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.</p>
    Formula:C17H15N3O6S2
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:421.45
  • p-Fluoro-L-phenylalanine

    CAS:
    <p>p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.</p>
    Formula:C9H10FNO2
    Purity:99.63%
    Color and Shape:White To Off-White Powder
    Molecular weight:183.18
  • Telotristat Etiprate

    CAS:
    <p>Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.</p>
    Formula:C27H26ClF3N6O3·C9H9NO3
    Purity:99.21% - 99.83%
    Color and Shape:White Solid
    Molecular weight:754.15
  • Mildronate

    CAS:
    <p>Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine</p>
    Formula:C6H14N2O2
    Purity:99.94%
    Color and Shape:White Crystalline Powder
    Molecular weight:146.19
  • TETRAHYDROPIPERINE

    CAS:
    <p>Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.</p>
    Formula:C17H23NO3
    Purity:98.04% - 99.61%
    Color and Shape:Off-White Low Melting Solid With Characteristic Odour
    Molecular weight:289.37
  • Nepicastat

    CAS:
    <p>Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.</p>
    Formula:C14H15F2N3S
    Color and Shape:Solid
    Molecular weight:295.35
  • Guanoclor

    CAS:
    <p>Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.</p>
    Formula:C9H12Cl2N4O
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:263.12