NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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IRAK4-IN-27
IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 …
Formula:
C23H22N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
430.46
Ref: TM-T79485
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HOIPIN-1
CAS:2470242-33-0
HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) …
Formula:
C17H13NaO4
Purity:
98.83%
Color and Shape:
Soild
Molecular weight:
304.27
Ref: TM-T78557
| 1mg | 183.00 € | ||
| 5mg | 435.00 € | ||
| 10mg | 635.00 € | ||
| 25mg | 1,000.00 € | ||
| 50mg | 1,336.00 € | ||
| 100mg | 1,803.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CTP-NBD
CAS:1268513-27-4
CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in …
Formula:
C121H194N46O32
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
2805.12
Ref: TM-T82665
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Anti-inflammatory agent 60
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, …
Purity:
98%
Ref: TM-T83052
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Anti-inflammatory agent 50
Anti-inflammatory agent 50 (compound a1), a derivative of Fusidic acid, exerts its effects through inhibition …
Formula:
C40H55N3O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
673.88
Ref: TM-T79585
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gliotoxin
CAS:67-99-2
Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks …
Formula:
C13H14N2O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
326.39
Ref: TM-TN1694
| 1mg | 141.00 € | ||
| 5mg | 601.00 € | ||
| 10mg | 996.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NT-0249
CAS:2763617-39-4
NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.
Formula:
C22H28N5NaO4S
Color and Shape:
Soild
Molecular weight:
481.54
Ref: TM-T85352
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 998.00 € | ||
| 50mg | 1,376.00 € | ||
| 100mg | 1,820.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NF-κB-IN-12
NF-κB-IN-12 (compound 3h) serves as a potent inhibitor of NF-κB, exhibiting an IC50 value of …
Formula:
C30H26N6O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
582.63
Ref: TM-T78882
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tripeptide-41
CAS:1093241-16-7
Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.
Formula:
C29H30N4O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
514.57
Ref: TM-T80208
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Narlumosbart
CAS:2646587-68-8
Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80618
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Anti-osteoporosis agent-4
Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.
Formula:
C26H26ClN3O7S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
560.02
Ref: TM-T78816
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IVMT-Rx-3
IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the …
Purity:
98%
Ref: TM-T82022
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ACHP
CAS:406208-42-2
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects …
Formula:
C21H24N4O2
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
364.44
Ref: TM-T22021
| 1mg | 52.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 367.00 € | ||
| 100mg | 625.00 € | ||
| 200mg | 1,019.00 € | ||
| 500mg | 2,037.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Velutin
CAS:25739-41-7
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in …
Formula:
C17H14O6
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
314.29
Ref: TM-T3816
| 1mg | 134.00 € | ||
| 5mg | 318.00 € | ||
| 10mg | 462.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SN50
CAS:213546-53-3
SN50 is a cell permeable NF-κB translocation inhibitor.
Formula:
C129H230N36O29S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
2781.5
Ref: TM-T12942
| 25mg | 867.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Salicortin
CAS:1887055-63-1
Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.
Formula:
C20H24O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
424.4
Ref: TM-T12828
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(R)-(-)-Ibuprofen
CAS:51146-57-7
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.
Formula:
C13H18O2
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
206.28
Ref: TM-T17309
| 50mg | 49.00 € | ||
| 100mg | 64.00 € | ||
| 200mg | 94.00 € | ||
| 500mg | 139.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MCC950
CAS:210826-40-7
CP-456773 (MCC950) inhibits NLRP3 inflammasome, prevents IL-1β secretion, and reduces multiple sclerosis model severity.
Formula:
C20H24N2O5S
Purity:
97%
Color and Shape:
Solid
Molecular weight:
404.48
Ref: TM-T3701
| 2mg | 35.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 390.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RIPK2/3-IN-1
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of …
Formula:
C24H16N4O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
456.54
Ref: TM-T79352
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mitogen-activated protein kinase 1
CAS:137632-08-7
Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80062
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
