NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Velutin
CAS:25739-41-7
Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in …
Formula:
C17H14O6
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
314.29
Ref: TM-T3816
| 1mg | 134.00 € | ||
| 5mg | 318.00 € | ||
| 10mg | 462.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(R)-(-)-Ibuprofen
CAS:51146-57-7
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.
Formula:
C13H18O2
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
206.28
Ref: TM-T17309
| 50mg | 49.00 € | ||
| 100mg | 64.00 € | ||
| 200mg | 94.00 € | ||
| 500mg | 139.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MCC950
CAS:210826-40-7
CP-456773 (MCC950) inhibits NLRP3 inflammasome, prevents IL-1β secretion, and reduces multiple sclerosis model severity.
Formula:
C20H24N2O5S
Purity:
97%
Color and Shape:
Solid
Molecular weight:
404.48
Ref: TM-T3701
| 2mg | 35.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 390.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SN50
CAS:213546-53-3
SN50 is a cell permeable NF-κB translocation inhibitor.
Formula:
C129H230N36O29S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
2781.5
Ref: TM-T12942
| 25mg | 867.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Salicortin
CAS:1887055-63-1
Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.
Formula:
C20H24O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
424.4
Ref: TM-T12828
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Goshonoside F5
CAS:90851-28-8
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both …
Formula:
C32H54O13
Purity:
98%
Color and Shape:
Solid
Molecular weight:
646.771
Ref: TM-TN4162
| 1mg | 357.00 € | ||
| 5mg | 1,756.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
INF 195
CAS:1211379-56-4
INF 195 is an inflammasome NLRP3 inhibitor that can be used to study myocardial ischemia …
Formula:
C17H22ClNO3
Color and Shape:
Soild
Molecular weight:
323.81
Ref: TM-T87945
| 5mg | 78.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 547.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK2/3-IN-1
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of …
Formula:
C24H16N4O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
456.54
Ref: TM-T79352
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Mitogen-activated protein kinase 1
CAS:137632-08-7
Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80062
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Cyclo(L-Pro-L-Val)
CAS:2854-40-2
Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and …
Formula:
C10H16N2O2
Purity:
98.18%
Color and Shape:
Liquid
Molecular weight:
196.25
Ref: TM-T125120
| 10mg | 46.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 132.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Coronalolic acid
CAS:268214-52-4
Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced …
Formula:
C30H46O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
470.68
Ref: TM-T13625
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SN50 TFA
SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 …
Formula:
C129H230N36O29S·XCF3COOH
Color and Shape:
Liquid
Molecular weight:
2781.5 (free base)
Ref: TM-T38153
| 1mg | 303.00 € | ||
| 5mg | 1,239.00 € | ||
| 500µg | 165.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GLPG2534
CAS:2095615-97-5
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 can …
Formula:
C21H24N6O4
Purity:
98.89% - 99.44%
Color and Shape:
Liquid
Molecular weight:
424.45
Ref: TM-T75113
| 1mg | 110.00 € | ||
| 5mg | 261.00 € | ||
| 10mg | 426.00 € | ||
| 25mg | 830.00 € | ||
| 50mg | 1,358.00 € | ||
| 100mg | 2,172.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Sootepin D
CAS:1154518-97-4
Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced …
Formula:
C31H48O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
484.71
Ref: TM-T12975
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NP3-146
CAS:210826-47-4
NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of …
Formula:
C20H27ClN2O5S
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
442.96
Ref: TM-T39552
| 1mg | 368.00 € | ||
| 5mg | 911.00 € | ||
| 10mg | 1,194.00 € | ||
| 25mg | 1,805.00 € | ||
| 50mg | 2,425.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Isophysalin A
CAS:1363398-67-7
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant …
Formula:
C28H30O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
526.53
Ref: TM-TN4318
| 5mg | 812.00 € | ||
| 1mL*10mM (DMSO) | 1,227.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
EN450
CAS:793719-01-4
EN450 is a targeted cysteine degrader of NF-κB with antiproliferative activity and potential anticancer activity …
Formula:
C11H13ClN2O3S
Purity:
99.72%
Color and Shape:
Soild
Molecular weight:
288.75
Ref: TM-T77525
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 422.00 € | ||
| 100mg | 614.00 € | ||
| 500mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Narasin (sodium salt)
CAS:58331-17-2
Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress …
Formula:
C43H71NaO11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
787.01
Ref: TM-T21577
| 5mg | 502.00 € | ||
| 25mg | 2,259.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Anti-inflammatory agent 51
CAS:2911610-03-0
Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury …
Formula:
C22H22N6O6S
Purity:
99.46%
Color and Shape:
Soild
Molecular weight:
498.51
Ref: TM-T77582
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 198.00 € | ||
| 100mg | 294.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BAL-0028
CAS:2842012-69-3
BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for …
Formula:
C24H22FN3O2
Purity:
99.16%
Color and Shape:
Soild
Molecular weight:
403.45
Ref: TM-T85341
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 641.00 € | ||
| 25mg | 1,000.00 € | ||
| 50mg | 1,379.00 € | ||
| 100mg | 1,823.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
