CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
Found 140 products of "CCR"
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ML604086
CAS:ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations.Formula:C27H32N4O4SPurity:99.91%Color and Shape:SolidMolecular weight:508.63CCR2-RA-[R]
CAS:CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).Formula:C18H19ClFNO3Purity:99.7%Color and Shape:SolidMolecular weight:351.8CCX140
CAS:CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.Formula:C20H13ClF3N5O3SPurity:99.66% - 99.95%Color and Shape:SolidMolecular weight:495.86AZ084
CAS:AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.Formula:C26H34N4O2Purity:97.12%Color and Shape:SolidMolecular weight:434.57Ref: TM-T10425
1mg84.00€5mg161.00€10mg245.00€25mg406.00€50mg572.00€100mg772.00€200mg1,035.00€1mL*10mM (DMSO)172.00€INCB-9471
CAS:INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.Formula:C30H40F3N5O2Purity:98.80%Color and Shape:SolidMolecular weight:559.666Mogamulizumab
CAS:Mogamulizumab is a monoclonal antibody targeting CC chemokine receptor 4 with anticancer effects, used in ATLL and CTCL studies.Purity:SDS-PAGE:97.3%;SEC-HPLC:99.4%Color and Shape:LiquidMolecular weight:146.43 kDaLeronlimab
CAS:Leronlimab (PRO 140), a humanized IgG4 monoclonal antibody, targets CCR5 to combat HIV and cancer.Purity:SDS-PAGE:95.0%;SEC-HPLC:99.6%Color and Shape:LiquidMolecular weight:146.66 kDaRS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formula:C21H22ClF3N2O2Purity:98.95%Color and Shape:SolidMolecular weight:426.86J-113863
CAS:J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM).Formula:C30H37Cl2IN2O2Purity:95.11%Color and Shape:SolidMolecular weight:655.44Ref: TM-T11699
1mg56.00€2mg82.00€5mg119.00€10mg160.00€25mg288.00€50mg500.00€100mg718.00€1mL*10mM (DMSO)170.00€MK-0812 Succinate
CAS:MK-0812 Succinate is an effective and selective CCR2 antagonist.Formula:C28H40F3N3O7Purity:98.62% - 99.93%Color and Shape:SolidMolecular weight:587.63Met-RANTES,human,acetate
Met-RANTES (human) acetate is the acetate salt form of Met-RANTES (human). It acts as an antagonist for CCR1 and CCR5 receptors. This compound inhibits the human chemokines MIP-1α and MIP-1β, with respective IC50 values of 5 and 2 nM. Additionally, Met-RANTES (human) acetate reduces bone destruction and alleviates adjuvant-induced arthritis (AIA) in rats.Color and Shape:Odour SolidMLN-3897 TFA
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.Formula:C32H32ClF3N2O6Purity:98.62%Color and Shape:SolidMolecular weight:633.05Ref: TM-T28072L
1mg115.00€5mg245.00€10mg363.00€25mg562.00€50mg775.00€100mg1,035.00€200mg1,406.00€1mL*10mM (DMSO)To inquireINCB 3284 dimesylate
CAS:INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Formula:C28H39F3N4O10S2Purity:98%Color and Shape:SolidMolecular weight:712.76BMS-753426
CAS:BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .
Formula:C25H33F3N6O2Color and Shape:SolidMolecular weight:506.574INCB3344 R-isomer
INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.Formula:C29H34F3N3O6Purity:98%Color and Shape:SolidMolecular weight:577.59Bertilimumab
CAS:Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].
Color and Shape:LiquidCCR4 antagonist 3
CAS:Orally active CCR4 antagonist with piperidinyl-azetidine; IC50: 22 nM (calcium flux), 50 nM (CTX); antitumor effects.Formula:C24H27Cl2N7OColor and Shape:SolidMolecular weight:500.43CCR4 antagonist 3 hydrochloride
CAS:Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.Formula:C24H27Cl2N7O·xHClColor and Shape:SolidZn-DPA-maytansinoid conjugate 1
Zn-DPA-maytansinoid 1 targets checkpoints, shrinks tumors, and heats TME.Formula:C115H145ClN18O31S2Zn2Color and Shape:SolidMolecular weight:2505.83Maceneolignan H
CAS:Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.Formula:C24H30O7Color and Shape:SolidMolecular weight:430.49PF-232798
CAS:PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.Formula:C29H40FN5O2Color and Shape:SolidMolecular weight:509.66CKLF1-C27 TFA
CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.Formula:C153H244F3N39O39Color and Shape:SolidMolecular weight:3310.8SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Formula:C22H26N4O5Color and Shape:SolidMolecular weight:426.47CCR8 antagonist 1
CAS:CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.Formula:C26H29N3O5SPurity:99.51%Color and Shape:SolidMolecular weight:495.59Plozalizumab
CAS:Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of
Purity:96.4%Color and Shape:LiquidMolecular weight:146.02 kDaCH-0076989
CAS:CH-0076989 is a chemokine receptor CCR3 agonist.Formula:C24H22Br2N2O2Color and Shape:SolidMolecular weight:530.25CCR6 antagonist 2
CCR6 antagonist2 (Compound 20c) acts as a CCR6 antagonist with a Ki of 1.1 nM. It inhibits CCL20-induced calcium influx with an IC50 of 4.9 nM and suppresses the chemotactic migration of CCR6+ T cells with an IC50 of 190 nM.Formula:C19H24N4O4Color and Shape:SolidMolecular weight:372.42CMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-Color and Shape:Odour SolidHGS101
HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.Color and Shape:Odour LiquidCCR6 antagonist 1
CAS:CCR6 antagonist 1 blocks CCL20/CCR6, aiding autoimmune and IBD research.
Formula:C17H12F3NO2Purity:99.83%Color and Shape:SoildMolecular weight:319.28CHS-114
CHS-114 (SRF-114) is a fully human IgG1 antibody targeting the (CCR8) receptor. It shows potential for research in head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can be referred to as HumanIgG1kappa, Isotype Control.Color and Shape:Odour LiquidTagmokitug
CAS:Tagmokitug is a humanized IgG1κ monoclonal antibody inhibitor targeting CCR8. It exhibits anti-tumor activity and is applicable in cancer immunotherapy research, including studies on breast cancer, colon cancer, and lung cancer.Lanerkitug
Lanerkitug is a humanized IgG1λ2 antibody that targets CCR8, with HumanIgG1lambda2, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidCafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidWAY-639418
CAS:WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.Formula:C17H16ClN5Purity:99.89%Color and Shape:SolidMolecular weight:325.8Chemokine Inhibitor Library
A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
Color and Shape:Odour Solid2-Methoxyhydroquinone
CAS:2-Methoxyhydroquinone inhibits MAO-A and MAO-B and reduces TNF-α-induced CCL2 production, a precursor for synthesising the Hsp90 inhibitor Geldanamycin.Formula:C7H8O3Purity:98.25%Color and Shape:SolidMolecular weight:140.14CCR6 inhibitor 1
CAS:CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding in vitro/vivo disease studies.
Formula:C24H23F3N4O3SPurity:99.89%Color and Shape:SolidMolecular weight:504.52Nebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidDenikitug
Denikitug is a chimeric antibody of the IgG1κ type that targets CCR8, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Color and Shape:Odour LiquidCCR2 antagonist 1
CAS:CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Formula:C28H32BrF3N2OColor and Shape:SolidMolecular weight:549.47NI-0701
NI-0701 is a humanized antibody targeting CCL5/RANTES.Purity:95.4% (SDS-PAGE); 99.4% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.83 kDaCCR8 agonist 1
CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.Formula:C22H29NO3Color and Shape:SolidMolecular weight:355.47ZK 756326
CAS:ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.Formula:C21H28N2O3Purity:99.43%Color and Shape:SolidMolecular weight:356.46Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Formula:C41H52N4O4SPurity:97.87%Color and Shape:SolidMolecular weight:696.94Ref: TM-TQ0297
1mg63.00€2mg90.00€5mg133.00€10mg212.00€25mg423.00€50mg550.00€100mg715.00€200mg964.00€1mL*10mM (DMSO)200.00€AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Formula:C11H9Cl2N3O3SPurity:99.80% - >99.99%Color and Shape:SolidMolecular weight:334.18Ref: TM-T4300
1mg34.00€5mg66.00€10mg105.00€25mg217.00€50mg334.00€100mg502.00€500mg1,063.00€1mL*10mM (DMSO)73.00€R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Formula:C21H27NO4Purity:99.03%Color and Shape:SolidMolecular weight:357.44Ref: TM-T24700
1mg40.00€2mg52.00€5mg80.00€10mg117.00€25mg207.00€50mg333.00€100mg495.00€1mL*10mM (DMSO)90.00€Vicriviroc maleate
CAS:Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.Formula:C32H42F3N5O6Purity:98.16% - 98.37%Color and Shape:SolidMolecular weight:649.7Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purity:98.35% - 98.55%Color and Shape:SolidMolecular weight:324.37Ref: TM-T6413
1mg35.00€2mg50.00€5mg75.00€10mg110.00€25mg178.00€50mg314.00€100mg492.00€200mg710.00€1mL*10mM (DMSO)84.00€BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Formula:C21H24ClFN4O3Purity:98% - 99.98%Color and Shape:SolidMolecular weight:434.89Ref: TM-T2375
1mg35.00€5mg86.00€10mg117.00€25mg200.00€50mg313.00€100mg489.00€200mg740.00€1mL*10mM (DMSO)95.00€SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Formula:C18H18N2O5Purity:99.59%Color and Shape:SolidMolecular weight:342.35Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Formula:C28H38F3N5O2Color and Shape:SolidMolecular weight:533.63CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Formula:C21H22Cl2F3N3O2Color and Shape:SolidMolecular weight:476.32RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purity:98.64% - 99.62%Color and Shape:SolidMolecular weight:417.5Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColor and Shape:SolidMolecular weight:467.92RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Formula:C20H16Cl2N4Purity:99.60% - 99.87%Color and Shape:SolidMolecular weight:383.27BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Formula:C25H40N8O2Purity:99.66% - 99.79%Color and Shape:SolidMolecular weight:484.64Ref: TM-T4584
1mg63.00€5mg137.00€10mg187.00€25mg341.00€50mg567.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)145.00€DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Formula:C35H56N10O15Purity:>99.99%Color and Shape:SolidMolecular weight:856.887,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:SolidMolecular weight:254.24PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purity:98.85% - 99.47%Color and Shape:SolidMolecular weight:568.59C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purity:99.74% - 99.90%Color and Shape:SolidMolecular weight:467.65Ref: TM-T21870
1mg49.00€2mg67.00€5mg90.00€10mg144.00€25mg286.00€50mg444.00€100mg622.00€1mL*10mM (DMSO)90.00€Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formula:C29H41F2N5OPurity:97.13% - 99.59%Color and Shape:Brown SolidMolecular weight:513.67Ref: TM-T6016
5mg49.00€10mg90.00€25mg152.00€50mg259.00€100mg465.00€200mg600.00€500mg945.00€1mL*10mM (DMSO)56.00€Vercirnon
CAS:Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.Formula:C22H21ClN2O4SPurity:99.23%Color and Shape:SolidMolecular weight:444.93Ref: TM-T17225
1mg105.00€5mg259.00€10mg406.00€25mg680.00€50mg938.00€100mg1,301.00€500mg2,593.00€1mL*10mM (DMSO)363.00€AZD-4818
CAS:AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C27H32Cl2N2O7Purity:99.01%Color and Shape:SolidMolecular weight:567.46RS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Formula:C21H21F3N2O2Purity:97.64% - 99.80%Color and Shape:SolidMolecular weight:390.4TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purity:97.81% - 99.42%Color and Shape:SolidMolecular weight:520.54Tivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFormula:C24H27Cl2F3N6OPurity:99.88%Color and Shape:SolidMolecular weight:543.41Ref: TM-T69834
1mg171.00€5mg418.00€10mg666.00€25mg1,334.00€50mg2,071.00€100mg2,879.00€1mL*10mM (DMSO)500.00€CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Formula:C21H24ClN5O3SPurity:98%Color and Shape:SolidMolecular weight:461.96YM022
CAS:YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.Formula:C32H28N4O3Purity:98%Color and Shape:SolidMolecular weight:516.59TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Formula:C31H41ClN4O3Purity:98%Color and Shape:SolidMolecular weight:553.14MLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Formula:C21H19ClN2O5SColor and Shape:SolidMolecular weight:446.9AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Formula:C11H8Cl2FN3O3SColor and Shape:SolidMolecular weight:352.17CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Formula:C20H16FN5O3SPurity:99.13%Color and Shape:SolidMolecular weight:425.44Ref: TM-T10710
1mg101.00€5mg241.00€10mg402.00€25mg727.00€50mg1,046.00€100mg1,525.00€1mL*10mM (DMSO)265.00€ALK4290
CAS:ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.Formula:C27H34ClN5O3Color and Shape:SolidMolecular weight:512.04RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Formula:C27H34Cl3N5O2Color and Shape:SolidMolecular weight:566.95CCR8 antagonist 2
CAS:CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.Formula:C23H30ClN3O3SColor and Shape:SolidMolecular weight:464.02BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Formula:C23H27N5O3SPurity:99.83% - 99.94%Color and Shape:SolidMolecular weight:453.56CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Formula:C17H25FN2O2Purity:99.87%Color and Shape:SolidMolecular weight:308.39Ref: TM-T10712
1mg66.00€5mg147.00€10mg225.00€25mg398.00€50mg532.00€100mg745.00€200mg982.00€1mL*10mM (DMSO)161.00€CCR4 antagonist 3-1
CAS:CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.
Formula:C14H12N2SPurity:99.53%Color and Shape:SolidMolecular weight:240.32PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.
Formula:C18H22ClF3N2O3SPurity:99.95%Color and Shape:SolidMolecular weight:438.89PNU-177864
CAS:PNU-177864 is a selective dopamine D3 receptor antagonist.Formula:C18H21F3N2O3SPurity:99.92%Color and Shape:SolidMolecular weight:402.43C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Formula:C27H43Cl2N5O2Purity:98.67%Color and Shape:SolidMolecular weight:540.57CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Formula:C22H22ClN7O2Purity:99.43% - 99.44%Color and Shape:SolidMolecular weight:451.91APC-3316 tosylate
CAS:APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.Formula:C39H46N4O7S2Color and Shape:SolidMolecular weight:746.94GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Formula:C21H24Cl2N4O3Purity:98.77%Color and Shape:SolidMolecular weight:451.35AF-399/42018025
CAS:AF-399/42018025 is a small-molecule CCR4 antagonist applied to investigate chemokine-mediated immune cell trafficking and inflammatory disease mechanisms.Formula:C26H16ClN3O4S3Purity:99.96%Color and Shape:SolidMolecular weight:566.07BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purity:98%Color and Shape:SolidMolecular weight:451JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Formula:C17H15F2N3O3SPurity:98%Color and Shape:SolidMolecular weight:379.38Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purity:99.53% - 99.78%Color and Shape:SolidMolecular weight:767.86Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Formula:C28H37BrN4O3Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:557.533CCR2 antagonist 5
CAS:JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation & diabetes.Formula:C22H25F3N4O3SPurity:99.98%Color and Shape:SolidMolecular weight:482.52BMS-817399
CAS:BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.Formula:C23H36ClN3O4Purity:99.7%Color and Shape:SolidMolecular weight:454Ref: TM-T26861
1mg152.00€5mg319.00€10mg485.00€25mg770.00€50mg1,035.00€100mg1,395.00€1mL*10mM (DMSO)356.00€SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formula:C21H18N2O5Purity:99.54%Color and Shape:SolidMolecular weight:378.38Ref: TM-T23321
1mg39.00€5mg82.00€10mg123.00€25mg250.00€50mg394.00€100mg618.00€200mg874.00€1mL*10mM (DMSO)69.00€BMS CCR2 22
CAS:BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.Formula:C28H34F3N5O4SPurity:99.65%Color and Shape:SolidMolecular weight:593.66Ref: TM-T14688
1mg55.00€5mg110.00€10mg173.00€25mg349.00€50mg532.00€100mg718.00€200mg964.00€1mL*10mM (DMSO)147.00€GSK2239633A
CAS:GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.Formula:C24H25ClN4O5S2Purity:99.82%Color and Shape:SolidMolecular weight:549.06Ref: TM-T11481
1mg35.00€5mg79.00€10mg118.00€25mg245.00€50mg355.00€100mg515.00€500mgTo inquire1mL*10mM (DMSO)87.00€CCR1 antagonist 6
CAS:CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
Formula:C21H23ClN4O3SPurity:99.02% - 99.15%Color and Shape:SolidMolecular weight:446.95Tanimilast
CAS:Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.Formula:C30H30Cl2F2N2O8SPurity:99.18%Color and Shape:SolidMolecular weight:687.54CCR4 antagonist 4
CAS:CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].Formula:C24H27Cl2N7OColor and Shape:SolidMolecular weight:500.42MLN-3897
CAS:MLN-3897 is an oral CCR1 antagonist, Ki 2.3 nM, blocks 125I-MIP-1α binding, and inhibits Akt signaling in MM cells.Formula:C30H31ClN2O4Purity:98.62%Color and Shape:SolidMolecular weight:519.03
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