CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
Found 154 products for "CCR".
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AZD-4818
CAS:AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C27H32Cl2N2O7Purity:99.01%Color and Shape:SolidMolecular weight:567.46ZK 756326
CAS:ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.Formula:C21H28N2O3Purity:99.43%Color and Shape:White SolidMolecular weight:356.46PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purity:98.85% - 99.47%Color and Shape:SolidMolecular weight:568.59RS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Formula:C21H21F3N2O2Purity:97.64% - 99.80%Color and Shape:SolidMolecular weight:390.4Vercirnon
CAS:Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.Formula:C22H21ClN2O4SPurity:99.23%Color and Shape:SolidMolecular weight:444.93Ref: TM-T17225
1mg100.00€5mg245.00€1mL*10mM (DMSO)269.00€10mg385.00€25mg645.00€50mg888.00€100mg1,234.00€500mg2,457.00€Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formula:C29H41F2N5OPurity:97.13% - 99.59%Color and Shape:SolidMolecular weight:513.67Ref: TM-T6016
5mg49.00€1mL*10mM (DMSO)56.00€10mg90.00€25mg152.00€50mg259.00€100mg465.00€200mg600.00€500mg945.00€C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purity:99.74% - 99.90%Color and Shape:White SolidMolecular weight:467.65Ref: TM-T21870
1mg49.00€2mg67.00€5mg90.00€1mL*10mM (DMSO)90.00€10mg144.00€25mg286.00€50mg444.00€100mg622.00€RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Formula:C20H16Cl2N4Purity:99.60% - 99.87%Color and Shape:White SolidMolecular weight:383.27Vicriviroc maleate
CAS:Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.Formula:C32H42F3N5O6Purity:98.16% - 98.37%Color and Shape:White SolidMolecular weight:649.7CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Formula:C21H22Cl2F3N3O2Color and Shape:SolidMolecular weight:476.327,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:White SolidMolecular weight:254.24Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColor and Shape:SolidMolecular weight:467.92Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Formula:C41H52N4O4SPurity:97.87%Color and Shape:Yellow SolidMolecular weight:696.94Ref: TM-TQ0297
1mg63.00€2mg90.00€5mg133.00€1mL*10mM (DMSO)200.00€10mg212.00€25mg423.00€50mg550.00€100mg715.00€200mg964.00€AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Formula:C11H9Cl2N3O3SPurity:99.80% - 99.94%Color and Shape:SolidMolecular weight:334.18Ref: TM-T4300
1mg34.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg105.00€25mg217.00€50mg334.00€100mg502.00€500mg1,063.00€DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Formula:C35H56N10O15Purity:>99.99%Color and Shape:White SolidMolecular weight:856.88BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Formula:C25H40N8O2Purity:99.66% - 99.79%Color and Shape:SolidMolecular weight:484.64Ref: TM-T4584
1mg59.00€5mg130.00€1mL*10mM (DMSO)138.00€10mg177.00€25mg324.00€50mg537.00€100mg767.00€500mg1,558.00€RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purity:98.64% - 99.68%Color and Shape:SolidMolecular weight:417.5Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Formula:C28H38F3N5O2Color and Shape:SolidMolecular weight:533.63Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purity:98.35% - 98.55%Color and Shape:SolidMolecular weight:324.37Ref: TM-T6413
1mg35.00€2mg50.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg110.00€25mg178.00€50mg314.00€100mg492.00€200mg710.00€SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Formula:C18H18N2O5Purity:99.59%Color and Shape:White SolidMolecular weight:342.35BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Formula:C21H24ClFN4O3Purity:98% - 99.98%Color and Shape:SolidMolecular weight:434.89Ref: TM-T2375
1mg35.00€5mg86.00€1mL*10mM (DMSO)95.00€10mg117.00€25mg200.00€50mg313.00€100mg489.00€200mg740.00€R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Formula:C21H27NO4Purity:99.03% - 99.16%Color and Shape:Yellow SolidMolecular weight:357.44Ref: TM-T24700
1mg40.00€2mg52.00€5mg80.00€1mL*10mM (DMSO)90.00€10mg117.00€25mg207.00€50mg333.00€100mg495.00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purity:97.81% - 99.46%Color and Shape:SolidMolecular weight:520.54Carlumab
CAS:Carlumab is a high-affinity human monoclonal antibody that targets CCL2, suppressing the recruitment of monocytes/macrophages in the tumour microenvironment.Purity:95%Color and Shape:Transparent LiquidMolecular weight:144.87 kDaAnti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5)
Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is a monoclonal antibody targeting mouse/human/rat CCL2/MCP-1, capable of blocking the CCL2 signalling pathway.Purity:99% - 99%Color and Shape:Transparent LiquidMolecular weight:150 kDaTivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFormula:C24H27Cl2F3N6OPurity:99.88%Color and Shape:SolidMolecular weight:543.41Ref: TM-T69834
1mg158.00€5mg385.00€1mL*10mM (DMSO)462.00€10mg625.00€25mg1,251.00€50mg2,008.00€100mg2,790.00€Lanerkitug
Lanerkitug is a humanized IgG1λ2 antibody that targets CCR8, with HumanIgG1lambda2, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidNebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidDenikitug
Denikitug is a chimeric antibody of the IgG1κ type that targets CCR8, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Color and Shape:Odour LiquidDenrakibart
Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.Color and Shape:Odour LiquidAzirkitug
Azirkitug is a humanized IgG1κ antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidCafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidYM022
CAS:YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.Formula:C32H28N4O3Purity:98%Color and Shape:SolidMolecular weight:516.59TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Formula:C31H41ClN4O3Purity:98%Color and Shape:SolidMolecular weight:553.14CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Formula:C21H24ClN5O3SPurity:98%Color and Shape:SolidMolecular weight:461.96CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Formula:C20H16FN5O3SPurity:99.13%Color and Shape:SolidMolecular weight:425.44Ref: TM-T10710
1mg94.00€5mg222.00€1mL*10mM (DMSO)245.00€10mg371.00€25mg682.00€50mg982.00€100mg1,431.00€AZ760
CAS:AZ760 is a CCR8 antagonist that demonstrates excellent potency, good lipophilicity, and a high free fraction in blood, but exhibits unacceptable hERG inhibition [1].Formula:C29H33N3O4Molecular weight:487.59GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Formula:C21H24Cl2N4O3Purity:98.77%Color and Shape:White SolidMolecular weight:451.35CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Formula:C22H22ClN7O2Purity:99.43% - 99.44%Color and Shape:SolidMolecular weight:451.91BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purity:98%Color and Shape:SolidMolecular weight:451PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.Formula:C18H22ClF3N2O3SPurity:99.95%Color and Shape:SolidMolecular weight:438.89PNU-177864
CAS:PNU-177864 is a selective dopamine D3 receptor antagonist.Formula:C18H21F3N2O3SPurity:99.92%Color and Shape:SolidMolecular weight:402.43RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Formula:C27H34Cl3N5O2Color and Shape:SolidMolecular weight:566.95JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Formula:C17H15F2N3O3SPurity:98%Color and Shape:SolidMolecular weight:379.38CCR4 antagonist 3-1
CAS:CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.Formula:C14H12N2SPurity:99.87%Color and Shape:SolidMolecular weight:240.32MLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Formula:C21H19ClN2O5SColor and Shape:SolidMolecular weight:446.9CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Formula:C17H25FN2O2Purity:99.87%Color and Shape:SolidMolecular weight:308.39Ref: TM-T10712
1mg66.00€5mg147.00€1mL*10mM (DMSO)161.00€10mg225.00€25mg398.00€50mg532.00€100mg745.00€200mg982.00€C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Formula:C27H43Cl2N5O2Purity:98.67%Color and Shape:White SolidMolecular weight:540.57APC-3316 tosylate
CAS:APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.Formula:C39H46N4O7S2Color and Shape:SolidMolecular weight:746.94
