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CCR

CCR

C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.

Found 136 products of "CCR"

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  • PNU-177864 hydrochloride
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    PNU-177864 hydrochloride

    CAS:
    <p>PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.</p>
    Formula:C18H22ClF3N2O3S
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:438.89

    Ref: TM-T12510

  • PNU-177864
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    PNU-177864

    CAS:
    <p>PNU-177864 is a selective dopamine D3 receptor antagonist.</p>
    Formula:C18H21F3N2O3S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:402.43

    Ref: TM-T23167

  • BMS-457
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    BMS-457

    CAS:
    <p>BMS-457 is a potent, CCR1-selective antagonist.</p>
    Formula:C24H35ClN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451

    Ref: TM-T26849

  • AZD-1678
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    AZD-1678

    CAS:
    <p>AZD-1678 is a potent CCR4 receptor antagonist.</p>
    Formula:C11H8Cl2FN3O3S
    Color and Shape:Solid
    Molecular weight:352.17

    Ref: TM-T26713

  • MLN3126
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    MLN3126

    CAS:
    <p>MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.</p>
    Formula:C21H19ClN2O5S
    Color and Shape:Solid
    Molecular weight:446.9

    Ref: TM-T62660

  • JNJ-27141491
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    JNJ-27141491

    CAS:
    <p>JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.</p>
    Formula:C17H15F2N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:379.38

    Ref: TM-T27674

  • TAK-220
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    TAK-220

    CAS:
    <p>TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).</p>
    Formula:C31H41ClN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:553.14

    Ref: TM-T16973

  • C-021 dihydrochloride
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    C-021 dihydrochloride

    CAS:
    <p>C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.</p>
    Formula:C27H43Cl2N5O2
    Purity:98.67%
    Color and Shape:Solid
    Molecular weight:540.57

    Ref: TM-T10639

  • CCR1 antagonist 6
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    CCR1 antagonist 6

    CAS:
    <p>CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).</p>
    Formula:C21H23ClN4O3S
    Purity:99.02% - 99.15%
    Color and Shape:Solid
    Molecular weight:446.95

    Ref: TM-T10708

  • Ancriviroc
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    Ancriviroc

    CAS:
    <p>Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.</p>
    Formula:C28H37BrN4O3
    Purity:99.76% - 99.82%
    Color and Shape:Solid
    Molecular weight:557.52

    Ref: TM-T30047

  • BMS CCR2 22
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    BMS CCR2 22

    CAS:
    <p>BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.</p>
    Formula:C28H34F3N5O4S
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:593.66

    Ref: TM-T14688

  • CCR2 antagonist 5
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    CCR2 antagonist 5

    CAS:
    <p>JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation &amp; diabetes.</p>
    Formula:C22H25F3N4O3S
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:482.52

    Ref: TM-T27682

  • BMS-817399
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    BMS-817399

    CAS:
    <p>BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.</p>
    Formula:C23H36ClN3O4
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:454

    Ref: TM-T26861

  • SB 328437
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    SB 328437

    CAS:
    <p>SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).</p>
    Formula:C21H18N2O5
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:378.38

    Ref: TM-T23321

  • Cosalane
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    Cosalane

    CAS:
    <p>Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.</p>
    Formula:C45H60Cl2O6
    Purity:99.53% - 99.78%
    Color and Shape:Solid
    Molecular weight:767.86

    Ref: TM-T23910

  • GSK2239633A
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    GSK2239633A

    CAS:
    <p>GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.</p>
    Formula:C24H25ClN4O5S2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:549.06

    Ref: TM-T11481

  • VCH-286
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    VCH-286

    CAS:
    <p>VCH-286 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist.</p>
    Formula:C34H50F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:600.78

    Ref: TM-T29100

  • PF-04634817 succinate
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    PF-04634817 succinate

    CAS:
    <p>PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.</p>
    Formula:C29H42F3N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:629.67

    Ref: TM-T12419

  • CCR2 antagonist 4
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    CCR2 antagonist 4

    CAS:
    <p>CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM</p>
    Formula:C21H21ClF3N3O2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:439.86

    Ref: TM-T13114

  • CCR4 antagonist 4
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    CCR4 antagonist 4

    CAS:
    <p>CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].</p>
    Formula:C24H27Cl2N7O
    Color and Shape:Solid
    Molecular weight:500.42

    Ref: TM-T84701