Nrf2
Nrf2 is a transcription factor that regulates the expression of antioxidant proteins and detoxification enzymes, playing a pivotal role in cellular defense against oxidative stress and inflammation. Activation of Nrf2 signaling provides protection against various diseases, including cancer, neurodegeneration, and cardiovascular disorders. Nrf2 modulators are being explored for their potential therapeutic applications in reducing oxidative damage and inflammation. At CymitQuimica, we provide a range of high-quality Nrf2 pathway modulators to support your research in oxidative stress, inflammation, and disease prevention.
Found 84 products for "Nrf2".
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Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormula:C21H24O10Purity:97.16%Color and Shape:SolidMolecular weight:436.4093AT 14 acetate
TAT 14 acetate, a 14-mer peptide, activates Nrf2, has anti-inflammatory effects, and targets Keap1 without altering Nrf2 mRNA.Formula:C139H234N48O41Purity:96.9%Color and Shape:SolidMolecular weight:3233.64AEM1
CAS:AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.Formula:C20H14FN3O2SPurity:98.37% - 99.88%Color and Shape:SolidMolecular weight:379.407ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurity:98.42% - 99.55%Color and Shape:SolidMolecular weight:477.403Brusatol
CAS:Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Formula:C26H32O11Purity:99.35% - 99.95%Color and Shape:SolidMolecular weight:520.5257Diroximel fumarate
CAS:Diroximel fumarate (Diroximel Fumarete), a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.Formula:C11H13NO6Purity:99.8% - 99.88%Color and Shape:SolidMolecular weight:255.224Kinsenoside
CAS:Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formula:C10H16O8Purity:99.2% - 99.92%Color and Shape:SolidMolecular weight:264.2292Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Formula:C15H20O5Purity:99.58%Color and Shape:SolidMolecular weight:280.3163CBR-470-1
CAS:CBR-470-1 is a glycolytic phosphoglycerate kinase 1 inhibitor and Nrf2 activator that exhibits neuroprotective activity by activating the Keap1-Nrf2 cascade.Formula:C14H20ClNO4S2Purity:98.87%Color and Shape:SolidMolecular weight:365.9Nrf2 activator-4
CAS:Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.Formula:C23H24ClF3N2O3Purity:98.53% - 98.89%Color and Shape:SolidMolecular weight:468.896Nrf2-Activator-12G
CAS:Nrf2-Activator-12G is a potent Nrf-2 activator.Formula:C15H13ClO3SPurity:99.92%Color and Shape:White SolidMolecular weight:308.78MSU38225
CAS:MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.Formula:C21H19N3Color and Shape:SolidMolecular weight:313.4(+)-DHMEQ
CAS:(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.Formula:C13H11NO5Color and Shape:SolidMolecular weight:261.2301MIND4-17
CAS:MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.Formula:C20H15N5O3SColor and Shape:SolidMolecular weight:405.43Keap1-Nrf2-IN-12
CAS:eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.Formula:C26H28N2O10S2Color and Shape:SolidMolecular weight:592.64Keap1-Nrf2-IN-13
CAS:Keap1-Nrf2-IN-13 is a Keap1-Nrf2 PPI inhibitor (IC₅₀ = 0.15 µM) that binds Keap1 polar residues (Asn414, Arg415, Arg483, Gln530).Formula:C28H32N2O10S2Color and Shape:SolidMolecular weight:620.69Nrf2 activator-5
CAS:Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.Formula:C25H30Cl2O6Color and Shape:SolidMolecular weight:497.41Keap1-Nrf2-IN-14
CAS:Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.Formula:C30H29NO8SColor and Shape:SolidMolecular weight:563.62NXPZ-2
CAS:NXPZ-2 is an orally active Keap1-Nrf2 PPI inhibitor (Kᵢ = 95 nM, EC₅₀ = 120–170 nM) that upregulates Nrf2 and alleviates Aβ-induced cognitive impairment.Formula:C27H27N5O7S2Color and Shape:SolidMolecular weight:597.66SPC-180002
CAS:SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 μM for SIRT1 and SIRT3, respectively.Formula:C18H23NO4Purity:98%Color and Shape:SolidMolecular weight:317.38
