TGF-beta/Smad
TGF-beta/Smad inhibitors are compounds that interfere with the TGF-beta (Transforming Growth Factor-beta) signaling pathway, which is mediated by Smad proteins. This pathway is involved in the regulation of cell growth, differentiation, apoptosis, and stem cell function. Dysregulation of TGF-beta/Smad signaling is associated with cancer, fibrosis, and other diseases. Inhibitors of this pathway are important tools for studying these conditions and developing potential therapies. At CymitQuimica, we provide TGF-beta/Smad inhibitors to support your research in cell signaling, oncology, and tissue repair.
Found 68 products for "TGF-beta/Smad".
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P17 Peptide
CAS:P17 Peptide, a human TGF-β1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-β1.Formula:C95H139N27O21Color and Shape:SolidMolecular weight:1995.29Cirevetmab
CAS:Cirevetmab (ZTS-00521426), a caninized monoclonal antibody targeting Canis lupus familiaris TGFB1, is classified as an immunoglobulin G2-kappa.Color and Shape:LiquidEmugrobart
Emugrobart is a humanized IgG1κ antibody targeted at GDF8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidRilogrotug
CAS:Rilogrotug is a humanized IgG1κ monoclonal antibody targeting GDF15, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Color and Shape:SoildLerdelimumab
CAS:Lerdelimumab (CAT-152) is an IgG4 monoclonal antibody targeting TGF-β2, used in glaucoma scarring research.Color and Shape:LiquidBintrafusp alfa
CAS:Bintrafusp alfa (M7824) is a protein consisting of the extracellular structural domain of TGF-βRII with a monoclonal antibody to human immunoglobulin G1.Purity:96.1% (SDS-PAGE); 99.2% (SEC-HPLC) - 96.1% (SDS-PAGE); 99.2% (SEC-HPLC)Color and Shape:LiquidMolecular weight:177.25 kDaAlantolactone
CAS:Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.Formula:C15H20O2Purity:99.02% - 99.66%Color and Shape:SolidMolecular weight:232.32Trimethylamine N-oxide dihydrate
CAS:TMANO Dihydrate, from trimethylamine oxidation, stabilizes proteins against sharks' urea.Formula:C3H13NO3Purity:98.75%Color and Shape:White CrystalMolecular weight:111.14BMP signaling agonist sb4
CAS:BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)Formula:C14H10BrNOSPurity:99.48% - 99.80%Color and Shape:SolidMolecular weight:320.2Ref: TM-T7799
5mg44.00€1mL*10mM (DMSO)48.00€10mg57.00€25mg94.00€50mg119.00€100mg177.00€200mg268.00€500mg465.00€BMS986260
CAS:BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).Formula:C18H12ClFN6OPurity:97.67%Color and Shape:SolidMolecular weight:382.78BIO-013077-01
CAS:BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.Formula:C17H13N5Purity:99.87%Color and Shape:SolidMolecular weight:287.32Ref: TM-T8330
1mg48.00€5mg96.00€1mL*10mM (DMSO)131.00€10mg133.00€25mg259.00€50mg371.00€100mg527.00€200mg713.00€SD-208
CAS:SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.Formula:C17H10ClFN6Purity:98.72% - 99.65%Color and Shape:SolidMolecular weight:352.75SRI-011381
CAS:SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H31N3OPurity:98.64%Color and Shape:SolidMolecular weight:329.48Asiaticoside
CAS:Asiaticoside, in Centella asiatica, may treat wounds/burns.Formula:C48H78O19Purity:98% - 99.96%Color and Shape:Red SolidMolecular weight:959.12LY3200882
CAS:LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).Formula:C24H29N5O3Purity:99.46% - 99.63%Color and Shape:SolidMolecular weight:435.52R-268712
CAS:R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formula:C20H18FN5OPurity:99.61%Color and Shape:SolidMolecular weight:363.39Ref: TM-T16708
1mg44.00€1mL*10mM (DMSO)92.00€5mg93.00€10mg130.00€25mg250.00€50mg378.00€100mg537.00€200mg762.00€(E)-SIS3
CAS:(E)-SIS3 (SIS3) is a Smad3 inhibitor (IC50=3 μM) selective.inhibits the differentiation of fibroblasts into myofibroblasts via TGF-β1. High-Quality, Low-Cost!Formula:C28H27N3O3·HClPurity:95.64% - 98%Color and Shape:SolidMolecular weight:489.99Ref: TM-T3636
1mg40.00€2mg54.00€5mg105.00€1mL*10mM (DMSO)114.00€10mg164.00€25mg326.00€50mg485.00€100mg692.00€500mg1,395.00€SRI-011381 hydrochloride
CAS:SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H32ClN3OPurity:99.32% - 99.41%Color and Shape:SolidMolecular weight:365.94Ref: TM-T5129
1mg34.00€2mg44.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg105.00€25mg215.00€50mg334.00€100mg497.00€200mg755.00€SJ000291942
CAS:SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.Formula:C16H15FN2O4Purity:99.66%Color and Shape:SolidMolecular weight:318.3Ref: TM-T4662
1mg34.00€2mg44.00€5mg63.00€1mL*10mM (DMSO)71.00€10mg100.00€25mg205.00€50mg349.00€100mg557.00€200mg790.00€Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Formula:C41H32O27Purity:98.91% - 99.71%Color and Shape:SolidMolecular weight:956.68Ref: TM-TQ0184
1mg66.00€5mg145.00€10mg203.00€1mL*10mM (DMSO)215.00€25mg409.00€50mg595.00€100mg833.00€
