STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
Found 110 products for "STAT".
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Atranorin
CAS:Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.Formula:C19H18O8Purity:98.76% - 99.57%Color and Shape:White SolidMolecular weight:374.3414CMD178 TFA
CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.Formula:C48H60F3N9O9Purity:>99.99%Color and Shape:SolidMolecular weight:964.05HO-3867
CAS:HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.Formula:C28H30F2N2O2Purity:91.18% - 99.21%Color and Shape:SolidMolecular weight:464.5468S3I-201
CAS:S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.Formula:C16H15NO7SPurity:97.83%Color and Shape:SolidMolecular weight:365.36Morusin
CAS:Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.Formula:C25H24O6Purity:98.68% - 99.8%Color and Shape:Yellow SolidMolecular weight:420.4545STAT5-IN-1
CAS:STAT5-IN-1 (STAT5 Inhibitor) is a cell-permeable inhibitor which suppresses Stat5 via binding to the SH2 domain.Formula:C16H11N3O3Purity:99.92% - ≥95%Color and Shape:White SolidMolecular weight:293.2768Balsalazide disodium dihydrate
CAS:Balsalazide sodium hydrate treats mild-to-moderate ulcerative colitis; higher doses enhance remission maintenance; it's safe and effective.Formula:C17H17N3Na2O8Purity:98.95% - 99.71%Color and Shape:SolidMolecular weight:437.31Napabucasin
CAS:Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.Formula:C14H8O4Purity:98.43% - 99.85%Color and Shape:SolidMolecular weight:240.21Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Formula:C19H24O5Purity:96.66% - 99.93%Color and Shape:White SolidMolecular weight:332.3909RO8191
CAS:RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formula:C14H5F6N5OPurity:98.15% - 98.85%Color and Shape:Yellow SolidMolecular weight:373.2128ZDZ-553
ZDZ-553 is an orally active STAT1 inhibitor with an IC50 value of 0.87 μM. It modulates the STAT1 signaling pathway, influencing downstream lipid metabolism and inflammatory pathways. In mouse models of non-alcoholic steatohepatitis (NASH), ZDZ-553 reduces liver steatosis and decreases inflammatory responses. ZDZ-553 also has distinct safety features and is suitable for research related to NASH.SBT-100
SBT-100 is a human monoclonal antibody (mAb) that targets STAT3. It inhibits IL-6-mediated nuclear translocation of P-STAT3 in HEp-2 and PANC-1 cells and demonstrates tumor growth inhibition in MDA-MB-231.MMPP
CAS:MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.Formula:C17H18O3Purity:98.87% - 99.83%Color and Shape:White SolidMolecular weight:270.32STAT3-IN-39
CAS:STAT3-IN-39 (compound 10K) is an orally active inhibitor of STAT3, demonstrating effective inhibition of STAT3 phosphorylation with an IC50 of 0.47 μM in NIH-3T3 cells. It hinders TGF-β1-induced fibrotic responses and prevents epithelial-mesenchymal transition in A549 cells. STAT3-IN-39 is applicable for research related to idiopathic pulmonary fibrosis.Formula:C20H17F3N2O3SColor and Shape:SolidMolecular weight:422.42NTZ-24
CAS:NTZ-24 is a selective STAT3 inhibitor for cervical cancer and oncogenic signaling pathway research.Formula:C10H5Cl2N3O3SPurity:99.50%Color and Shape:SolidMolecular weight:318.14inS3-54-A26
CAS:inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.Formula:C25H19ClN2O2Purity:99.57%Color and Shape:SolidMolecular weight:414.884inS3-54A18
CAS:inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.Formula:C23H16ClNO2Purity:99.68%Color and Shape:SolidMolecular weight:373.832STAT6-IN-3
CAS:STAT6-IN-3 (Compound 18a) serves as an inhibitor of STAT6 with an IC50 value of 44 nM, specifically targeting the Src Homology 2 (SH2) domain.Formula:C32H35IN3O7PPurity:98%Color and Shape:SolidMolecular weight:731.51ML115
CAS:ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.Formula:C15H15ClN2O4Purity:99.97%Color and Shape:SolidMolecular weight:322.744Antitumor agent-73
CAS:Antitumor Agent-73, derived from Diosgenin, blocks STAT3 and activates Pdia3, showing strong cancer cell line efficacy.Formula:C50H82BrO4PPurity:98%Color and Shape:SolidMolecular weight:858.06
