STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
Found 98 products of "STAT"
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Saikosaponin D
CAS:<p>Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.</p>Formula:C42H68O13Purity:98.34% - 99.73%Color and Shape:White PowderMolecular weight:780.98Protosappanin A
CAS:<p>Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.</p>Formula:C15H12O5Purity:99.42% - 99.82%Color and Shape:SolidMolecular weight:272.25AS1517499
CAS:<p>AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!</p>Formula:C20H20ClN5O2Purity:98.27% - 98.7%Color and Shape:SolidMolecular weight:397.86BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Formula:C14H13N3OSPurity:99.02%Color and Shape:SolidMolecular weight:271.34Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84AS1810722
CAS:<p>AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM.</p>Formula:C25H25F2N7OPurity:99.13%Color and Shape:SolidMolecular weight:477.511-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Formula:C21H13ClF3N3O2Purity:99.41%Color and Shape:SolidMolecular weight:431.8Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.3C188-9
CAS:<p>C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.</p>Formula:C27H21NO5SPurity:98.07% - >99.99%Color and Shape:SolidMolecular weight:471.52Casticin
CAS:<p>Casticin combats vascular inflammation by blocking ROS-NF-κB and could lead in prostate cancer treatment.</p>Formula:C19H18O8Purity:99.37% - ≥95%Color and Shape:SolidMolecular weight:374.34Fraxinellone
CAS:<p>1.</p>Formula:C14H16O3Purity:99.35% - 99.92%Color and Shape:SolidMolecular weight:232.27Corylifol A
CAS:<p>1.</p>Formula:C25H26O4Purity:97.19% - 99.5%Color and Shape:SolidMolecular weight:390.47AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formula:C17H14N2O3Purity:98.6% - 99.39%Color and Shape:Yellow SolidMolecular weight:294.3Alantolactone
CAS:<p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>Formula:C15H20O2Purity:99.02% - 99.66%Color and Shape:Crystalline PowderMolecular weight:232.32Angoline
CAS:<p>Angoline hydrochloride: IL6/STAT3 inhibitor, IC50: 11.56 μM, blocks STAT3 phosphorylation and cancer cell growth.</p>Formula:C22H21NO5Purity:99.43% - 99.96%Color and Shape:SolidMolecular weight:379.41Mogrol
CAS:<p>Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.</p>Formula:C30H52O4Purity:99.85% - 99.90%Color and Shape:SolidMolecular weight:476.73Colivelin
CAS:<p>Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).</p>Formula:C119H206N32O35Purity:96.56%Color and Shape:SolidMolecular weight:2645.1Curculigoside
CAS:<p>1.</p>Formula:C22H26O11Purity:99.85%Color and Shape:SolidMolecular weight:466.44Stafia-1
CAS:<p>Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.</p>Formula:C24H27O10PPurity:98.08%Color and Shape:SolidMolecular weight:506.44Ochromycinone
CAS:<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Formula:C19H14O4Purity:99.21%Color and Shape:SolidMolecular weight:306.31
