STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
Found 110 products for "STAT".
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ML116
CAS:ML116 is a potent and selective STAT3 inhibitor.Formula:C18H19N3SPurity:99.49%Color and Shape:SolidMolecular weight:309.429Corylifol A
CAS:1.Formula:C25H26O4Purity:97.19% - 99.5%Color and Shape:SolidMolecular weight:390.4715AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purity:98.6% - 99.85%Color and Shape:Yellow SolidMolecular weight:294.3Alantolactone
CAS:Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.Formula:C15H20O2Purity:99.02% - 99.66%Color and Shape:SolidMolecular weight:232.32Angoline
CAS:Angoline hydrochloride: IL6/STAT3 inhibitor, IC50: 11.56 μM, blocks STAT3 phosphorylation and cancer cell growth.Formula:C22H21NO5Purity:99.43% - 99.96%Color and Shape:SolidMolecular weight:379.4058Mogrol
CAS:Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.Formula:C30H52O4Purity:99.85% - 99.95%Color and Shape:Yellow SolidMolecular weight:476.7315Colivelin
CAS:Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).Formula:C119H206N32O35Purity:99.65%Color and Shape:SolidMolecular weight:2645.1Curculigoside
CAS:1.Formula:C22H26O11Purity:99.84% - 99.85%Color and Shape:SolidMolecular weight:466.4352SC-43
CAS:SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.795BP-1-102
CAS:BP-1-102 is an orally active, effective and specific STAT3 inhibitor.Formula:C29H27F5N2O6SPurity:99.25% - 99.44%Color and Shape:White SolidMolecular weight:626.591SH-4-54
CAS:SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.Formula:C29H27F5N2O5SPurity:98% - 99.12%Color and Shape:SolidMolecular weight:610.592SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:Yellow SolidMolecular weight:336.148Pimozide
CAS:Pimozide: antipsychotic that blocks type 2 dopamine, alpha-adrenergic, and 5-HT2 receptors, reducing tics and delusions.Formula:C28H29F2N3OPurity:99.63% - >99.99%Color and Shape:SolidMolecular weight:461.55WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formula:C17H14BrN3OPurity:98.59% - 99.73%Color and Shape:SolidMolecular weight:356.217Cucurbitacin I
CAS:Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.Formula:C30H42O7Purity:96.69% - 99.8%Color and Shape:SolidMolecular weight:514.65RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormula:C17H20N4O2Purity:99.30%Color and Shape:SolidMolecular weight:312.3663Cryptotanshinone
CAS:Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.Formula:C19H20O3Purity:97.94% - ≥95%Color and Shape:Orange SolidMolecular weight:296.36Scutellarin
CAS:Scutellarin from Scutellaria inhibits RANKL in osteoclasts and STAT3/Girdin/Akt in HCC cells.Formula:C21H18O12Purity:98.64% - 99.75%Color and Shape:SolidMolecular weight:462.3604Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purity:99.97% - >99.99%Color and Shape:SolidMolecular weight:346.4174AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:99.40% - >99.99%Color and Shape:White SolidMolecular weight:405.241
