Pim
Pim kinases are a family of serine/threonine kinases that play a key role in cell survival, proliferation, and apoptosis. These kinases are downstream effectors in the JAK/STAT signaling pathway and are involved in various physiological processes, including immune responses and hematopoiesis. Overexpression of Pim kinases has been associated with the development of cancer, making them important targets for therapeutic intervention. At CymitQuimica, we offer a variety of high-quality Pim kinase inhibitors and modulators to support your research in oncology, cell biology, and signal transduction.
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Uzansertib phosphate
CAS:2088852-47-3
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, …
Formula:
C26H29F3N5O7P
Purity:
98% - 99.75%
Color and Shape:
Solid
Molecular weight:
611.51
Ref: TM-T12477
| 1mg | 94.00 € | ||
| 5mg | 275.00 € | ||
| 10mg | 410.00 € | ||
| 25mg | 677.00 € | ||
| 50mg | 922.00 € | ||
| 100mg | 1,290.00 € |
Estimated delivery in United States, on Monday 23 Sep 2024
Pim-1 kinase inhibitor 8
CAS:916038-47-6
Pim-1 kinase inhibitor 8 is a Pim-1 kinase inhibitor with anticancer activity that inhibits cell …
Formula:
C14H17N3O3
Purity:
99.81%
Color and Shape:
Soild
Molecular weight:
275.3
Ref: TM-T83627
| 1mg | 61.00 € | ||
| 5mg | 133.00 € | ||
| 10mg | 206.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 664.00 € | ||
| 100mg | 1,045.00 € | ||
| 500mg | 2,116.00 € |
Estimated delivery in United States, on Wednesday 25 Sep 2024
CX-6258 hydrochloride
CAS:1353859-00-3
CX-6258 hydrochloride (Pim-Kinase Inhibitor X) is an effective, orally efficacious Pim1/2/3 kinase inhibitor (IC50: 5/25/16 …
Formula:
C26H24ClN3O3·HCl
Purity:
96.03% - 98.00%
Color and Shape:
Solid
Molecular weight:
498.4
Ref: TM-T6148
| 1mg | 42.00 € | ||
| 1ml | 87.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 249.00 € | ||
| 50mg | 415.00 € | ||
| 100mg | 601.00 € | ||
| 500mg | 1,236.00 € |
Estimated delivery in United States, on Wednesday 25 Sep 2024
Pim-1/2 kinase inhibitor 1
CAS:6320-51-0
Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.
Formula:
C11H9NO3S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
235.26
Ref: TM-T9229
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 553.00 € | ||
| 500mg | 1,160.00 € |
Estimated delivery in United States, on Wednesday 25 Sep 2024
(2R)-Octyl-α-hydroxyglutarate
CAS:1391194-67-4
(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.
Formula:
C13H24O5
Color and Shape:
Solid
Molecular weight:
260.33
Ref: TM-T19611
| 1ml | 130.00 € | ||
| 2mg | 91.00 € |
Estimated delivery in United States, on Wednesday 25 Sep 2024
TP-3654
CAS:1361951-15-6
TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).
Formula:
C22H25F3N4O
Purity:
97.72% - 99.95%
Color and Shape:
Solid
Molecular weight:
418.46
Ref: TM-T4523
| 1ml | 57.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 148.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 345.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
HJ-PI01
CAS:6192-43-4
HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in …
Formula:
C14H11NO2
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
225.24
Ref: TM-T9583
| 1mg | 52.00 € | ||
| 1ml | 114.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 626.00 € | ||
| 100mg | 891.00 € | ||
| 500mg | 1,789.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
Hispidulin
CAS:1447-88-7
Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor …
Formula:
C16H12O6
Purity:
97.54% - 98.53%
Color and Shape:
Solid
Molecular weight:
300.26
Ref: TM-TQ0201
| 1ml | 69.00 € | ||
| 10mg | 88.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
TCS-PIM-1-4a
CAS:327033-36-3
SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).
Formula:
C11H6F3NO2S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
273.23
Ref: TM-T4215
| 1ml | 55.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 315.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
SMI-16a
CAS:587852-28-6
SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive …
Formula:
C13H13NO3S
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
263.31
Ref: TM-T3989
| 1mg | 35.00 € | ||
| 1ml | 92.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 346.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
Quercetagetin
CAS:90-18-6
Quercetagetin, a flavonoid from Citrus unshiu, inhibits pim-1 kinase (IC50: 0.34 μM), cell-permeable.
Formula:
C15H10O8
Purity:
99.65% - 99.76%
Color and Shape:
Solid
Molecular weight:
318.24
Ref: TM-T8114
| 1mg | 87.00 € | ||
| 1ml | 213.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 297.00 € | ||
| 25mg | 498.00 € | ||
| 50mg | 719.00 € | ||
| 100mg | 975.00 € | ||
| 500mg | 1,941.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
AZD1208
CAS:1204144-28-4
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency …
Formula:
C21H21N3O2S
Purity:
97.24% - 98.87%
Color and Shape:
Solid
Molecular weight:
379.48
Ref: TM-T2300
| 1ml | 57.00 € | ||
| 2mg | 38.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 210.00 € | ||
| 100mg | 370.00 € | ||
| 200mg | 487.00 € | ||
| 500mg | 778.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
SGI-1776
CAS:1025065-69-3
SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, …
Formula:
C20H22F3N5O
Purity:
100% - 99.84%
Color and Shape:
Solid
Molecular weight:
405.42
Ref: TM-T3078
| 1ml | 98.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 428.00 € | ||
| 100mg | 549.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
(Z)-SMI-4a
CAS:438190-29-5
(Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of …
Formula:
C11H6F3NO2S
Purity:
97.66% - 99.44%
Color and Shape:
Solid
Molecular weight:
273.23
Ref: TM-T3058
| 1ml | 52.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 318.00 € | ||
| 200mg | 479.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
Pim1/AKK1-IN-1
CAS:1093222-27-5
Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.
Formula:
C20H13N5O
Purity:
97.84% - 98.69%
Color and Shape:
Solid
Molecular weight:
339.35
Ref: TM-T5093
| 1mg | 88.00 € | ||
| 1ml | 201.00 € | ||
| 2mg | 129.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 479.00 € | ||
| 50mg | 697.00 € | ||
| 100mg | 978.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
TCS PIM-1 1
CAS:491871-58-0
TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an …
Formula:
C18H11BrN2O2
Purity:
97% - 99.64%
Color and Shape:
Solid
Molecular weight:
367.2
Ref: TM-T2253
| 1ml | 96.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 339.00 € | ||
| 100mg | 501.00 € |
Estimated delivery in United States, on Monday 30 Sep 2024
K00135
CAS:869650-21-5
K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in …
Formula:
C18H18N4O
Purity:
97.88%
Color and Shape:
Solid
Molecular weight:
306.36
Ref: TM-T27704
| 1mg | 182.00 € | ||
| 1ml | 413.00 € | ||
| 2mg | 272.00 € | ||
| 5mg | 417.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,291.00 € | ||
| 100mg | 1,746.00 € | ||
| 500mg | 3,509.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
CX-6258
CAS:1202916-90-2
CX-6258 is an orally valid Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor. It has good …
Formula:
C26H24ClN3O3
Purity:
95.88%
Color and Shape:
Solid
Molecular weight:
461.94
Ref: TM-T1834
| 1mg | 40.00 € | ||
| 1ml | 87.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 386.00 € | ||
| 100mg | 548.00 € | ||
| 200mg | 796.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
M-110
CAS:1395048-49-3
M-110 selectively targets PIM kinases, best at PIM-3 (IC50=47nM), and inhibits prostate cancer cell growth …
Formula:
C22H28ClN5O3
Purity:
98.30%
Color and Shape:
Solid
Molecular weight:
445.94
Ref: TM-T15830
| 1ml | 64.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 12 Nov 2024
PIM-IN-2
CAS:1006699-45-1
PIM-IN-2 (Pim-2) is a potent inhibitor of Pim kinases, demonstrating an inhibition concentration half-maximal (IC50) …
Formula:
C19H22N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
338.4
Ref: TM-T81460
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
PIM1-IN-4
CAS:2762767-48-4
PIM1-IN-4: strong PIM1 inhibitor, also blocks SGK-1, PKA, CaMK-1, GSK3β, MSK1; promising for cancer studies.
Formula:
C27H25BrCl2CuN6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
663.88
Ref: TM-T73247
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
PIM1-IN-1
CAS:1417630-95-5
PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it …
Formula:
C25H30N8O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
474.56
Ref: TM-T12474
| 25mg | 1,058.00 € | ||
| 50mg | 1,385.00 € | ||
| 100mg | 2,258.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
GNE-955
CAS:1527523-39-2
GNE-955 is a potent and orally active inhibitor of pan Pim kinase (Kis: 0.018, 0.11, …
Formula:
C22H24N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
416.48
Ref: TM-T15406
| 25mg | 1,822.00 € | ||
| 50mg | 2,413.00 € | ||
| 100mg | 3,180.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
HS94
CAS:1892594-93-2
HS94 (DAPK3 inhibitor HS94) is a selective and potent DAPK3 inhibitor with a Ki value …
Formula:
C15H15N5O2S
Purity:
95.04%
Color and Shape:
Solid
Molecular weight:
329.38
Ref: TM-T77777
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 224.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 494.00 € | ||
| 500mg | 1,058.00 € |
Estimated delivery in United States, on Monday 25 Nov 2024
Pim-1 kinase inhibitor 5
CAS:2928606-67-9
Pim-1 kinase inhibitor 5 (Compound 4c), with an IC50 of 0.61 μM, exhibits cytotoxicity against …
Formula:
C22H13Cl2N3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.26
Ref: TM-T78980
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
FD1024
CAS:1422456-47-0
FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, …
Formula:
C21H20F2N4O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
430.47
Ref: TM-T79456
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 25 Nov 2024
GDC-0339
CAS:1428569-85-0
GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - …
Formula:
C20H22F3N7OS
Color and Shape:
Solid
Molecular weight:
465.5
Ref: TM-T15376
| 25mg | 1,531.00 € | ||
| 50mg | 2,013.00 € | ||
| 100mg | 3,491.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
