JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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JAK2-IN-6
CAS:353512-04-6
JAK2-IN-6: A potent JAK2-specific inhibitor (IC50=22.86μg/mL), blocks JAK2 signaling, has anticancer properties, and is inactive …
Formula:
C14H10ClN3OS2
Purity:
99.38%
Color and Shape:
Liquid
Molecular weight:
335.83
Ref: TM-T40443
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 208.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | 462.00 € | ||
| 500mg | 1,008.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
JAK-IN-33
JAK-IN-33 (Compound 3 (R)) is a selective inhibitor of the Janus kinase (JAK) family [1].
Purity:
98%
Ref: TM-T82018
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
JAK/HDAC-IN-2
JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations.
Formula:
C28H38N6O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
570.7
Ref: TM-T78708
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Povorcitinib phosphate
CAS:1637677-33-8
Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the …
Formula:
C23H25F5N7O5P
Purity:
97.71%
Color and Shape:
Liquid
Molecular weight:
605.45
Ref: TM-T39113L
| 1mg | 65.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 695.00 € | ||
| 200mg | 937.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Cerdulatinib hydrochloride
CAS:1369761-01-2
Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others …
Formula:
C20H28ClN7O3S
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
482
Ref: TM-T6104
| 2mg | 37.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 117.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 259.00 € | ||
| 200mg | 369.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
GS-829845
CAS:1257705-09-1
GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which …
Formula:
C17H19N5O2S
Purity:
99.78%
Color and Shape:
Liquid
Molecular weight:
357.43
Ref: TM-T67905
| 5mg | 47.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 126.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
WHI-P180 Hydrochloride
CAS:153437-55-9
Formula:
C16H15N3O3·HCl
Purity:
>97.0%(T)(HPLC)
Color and Shape:
White to Light gray to Light yellow powder to crystal
Molecular weight:
333.77
Ref: 3B-W0021
| 25mg | 169.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
WHI-P154
CAS:211555-04-3
Formula:
C16H14BrN3O3
Purity:
>98.0%(HPLC)
Color and Shape:
White to Yellow to Orange powder to crystal
Molecular weight:
376.21
Ref: 3B-W0013
| 10mg | 70.00 € | ||
| 50mg | 238.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
DTP3
CAS:1809784-29-9
DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
Formula:
C26H35N7O5
Color and Shape:
Solid
Molecular weight:
525.6
Ref: TM-T22319
| 2mg | 84.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 216.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Momelotinib sulfate
CAS:1056636-06-6
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity …
Formula:
C23H26N6O10S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
610.62
Ref: TM-T15038
| 2mg | 50.00 € | ||
| 5mg | 85.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Tyrphostin AG 490
CAS:133550-30-8
Formula:
C17H14N2O3
Purity:
>98.0%(T)(HPLC)
Color and Shape:
White to Light yellow powder to crystal
Molecular weight:
294.31
Ref: 3B-T2962
| 1g | 756.00 € | ||
| 20mg | 46.00 € | ||
| 100mg | 128.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
CHZ868
CAS:1895895-38-1
CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence …
Formula:
C22H19F2N5O2
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
423.42
Ref: TM-TQ0061
| 2mg | 73.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Ifidancitinib
CAS:1236667-40-5
Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.
Formula:
C20H18FN5O3
Purity:
98.05%
Color and Shape:
Liquid
Molecular weight:
395.39
Ref: TM-T38623
| 1mg | 146.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Decernotinib
CAS:944842-54-0
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki …
Formula:
C18H19F3N6O
Purity:
100% - 99.45%
Color and Shape:
Solid
Molecular weight:
392.38
Ref: TM-T2636
| 2mg | 69.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 133.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 653.00 € | ||
| 200mg | 922.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
G5-7
CAS:939681-36-4
G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.
Formula:
C22H19F2NO3
Purity:
97.30%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T8742
| 1mg | 50.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 374.00 € | ||
| 100mg | 523.00 € | ||
| 200mg | 710.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
(E/Z)-Zotiraciclib
CAS:937270-47-8
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 …
Formula:
C23H24N4O
Purity:
97% - 98.03%
Color and Shape:
Solid
Molecular weight:
372.46
Ref: TM-T21503
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 507.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
FLLL32
CAS:1226895-15-3
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
Formula:
C28H32O6
Purity:
96.39% - 97.90%
Color and Shape:
Solid
Molecular weight:
464.55
Ref: TM-T6838
| 2mg | 46.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 350.00 € | ||
| 500mg | 840.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
GDC-0214
CAS:1831144-46-7
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
Formula:
C28H28ClF2N9O3
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
612.03
Ref: TM-T9826
| 1mg | 87.00 € | ||
| 5mg | 192.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 867.00 € | ||
| 200mg | 1,159.00 € | ||
| 1mL*10mM (DMSO) | 259.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Baricitinib
CAS:1187594-09-7
Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. …
Formula:
C16H17N7O2S
Purity:
100% - 99.79%
Color and Shape:
Solid
Molecular weight:
371.42
Ref: TM-T2485
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 115.00 € | ||
| 100mg | 144.00 € | ||
| 200mg | 188.00 € | ||
| 500mg | 311.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Pyridone 6
CAS:457081-03-7
Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 …
Formula:
C18H16FN3O
Purity:
97.10% - 98.74%
Color and Shape:
Solid
Molecular weight:
309.34
Ref: TM-T3080
| 1mg | 82.00 € | ||
| 2mg | 106.00 € | ||
| 5mg | 162.00 € | ||
| 10mg | 221.00 € | ||
| 25mg | 449.00 € | ||
| 50mg | 658.00 € | ||
| 100mg | 939.00 € | ||
| 500mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 177.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
