JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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WHI-P97
CAS:211555-05-4
WHI-P97 is a rationally designed potent inhibitor of JAK-3.
Formula:
C16H13Br2N3O3
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
455.1
Ref: TM-T4657
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 190.00 € | ||
| 100mg | 284.00 € | ||
| 200mg | 400.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
BD750
CAS:892686-59-8
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 …
Formula:
C14H13N3OS
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
271.34
Ref: TM-T8546
| 5mg | 51.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 389.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Formula:
C16H13Cl2N3O2
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
350.2
Ref: TM-T22338
| 1mg | 50.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 722.00 € | ||
| 200mg | 938.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Solcitinib
CAS:1206163-45-2
Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.
Formula:
C22H23N5O2
Purity:
99.61% - 99.82%
Color and Shape:
Solid
Molecular weight:
389.45
Ref: TM-T3620
| 5mg | 50.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 117.00 € | ||
| 100mg | 187.00 € | ||
| 200mg | 301.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
WHI-P154
CAS:211555-04-3
WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
Formula:
C16H14BrN3O3
Purity:
98% - 99.6%
Color and Shape:
Solid
Molecular weight:
376.2
Ref: TM-T1985
| 2mg | 42.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 331.00 € | ||
| 100mg | 538.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
AT9283
CAS:896466-04-9
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, …
Formula:
C19H23N7O2
Purity:
99.83% - 99.98%
Color and Shape:
Solid
Molecular weight:
381.43
Ref: TM-T3068
| 1mg | 47.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 723.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Gandotinib
CAS:1229236-86-5
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).
Formula:
C23H25ClFN7O
Purity:
99.33% - 99.86%
Color and Shape:
Solid
Molecular weight:
469.94
Ref: TM-T2638
| 5mg | 51.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 296.00 € | ||
| 100mg | 469.00 € | ||
| 500mg | 1,035.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
CEP-33779
CAS:1257704-57-6
CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.
Formula:
C24H26N6O2S
Purity:
98.81% - ≥95%
Color and Shape:
Solid
Molecular weight:
462.57
Ref: TM-T6122
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 245.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 560.00 € | ||
| 500mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Filgotinib
CAS:1206161-97-8
Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and …
Formula:
C21H23N5O3S
Purity:
98.03% - ≥95%
Color and Shape:
Solid
Molecular weight:
425.5
Ref: TM-T1929
| 1mg | 39.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 329.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Baricitinib phosphate
CAS:1187595-84-1
Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.
Formula:
C16H20N7O6PS
Purity:
98.87% - 99.68%
Color and Shape:
Solid
Molecular weight:
469.41
Ref: TM-T2360
| 5mg | 48.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 115.00 € | ||
| 100mg | 144.00 € | ||
| 500mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.
Formula:
C16H14Br2ClN3O3
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
491.56
Ref: TM-T4657L
| 1mg | 42.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 395.00 € | ||
| 200mg | 562.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Ritlecitinib
CAS:1792180-81-4
Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity …
Formula:
C15H19N5O
Purity:
98.82% - 99.92%
Color and Shape:
Solid
Molecular weight:
285.34
Ref: TM-T5382
| 2mg | 47.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 495.00 € | ||
| 200mg | 705.00 € | ||
| 500mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Abrocitinib
CAS:1622902-68-4
Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for …
Formula:
C14H21N5O2S
Purity:
99.09% - 99.91%
Color and Shape:
Solid
Molecular weight:
323.41
Ref: TM-TQ0037
| 1mg | 85.00 € | ||
| 2mg | 107.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 467.00 € | ||
| 50mg | 692.00 € | ||
| 100mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Atractylenolide I
CAS:73069-13-3
Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to …
Formula:
C15H18O2
Purity:
97.55% - 99.83%
Color and Shape:
Solid
Molecular weight:
230.3
Ref: TM-T5S0167
| 1mg | 43.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 592.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
XL019
CAS:945755-56-6
XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold …
Formula:
C25H28N6O2
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
444.53
Ref: TM-T3072
| 5mg | 74.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
WP1066
CAS:857064-38-1
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in …
Formula:
C17H14BrN3O
Purity:
98.92% - 99.73%
Color and Shape:
Solid
Molecular weight:
356.22
Ref: TM-T2156
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 213.00 € | ||
| 100mg | 299.00 € | ||
| 500mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
AZ960
CAS:905586-69-8
AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
Formula:
C18H16F2N6
Purity:
96.02% - 98.51%
Color and Shape:
Solid
Molecular weight:
354.36
Ref: TM-T6309
| 1mg | 73.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 197.00 € | ||
| 25mg | 363.00 € | ||
| 50mg | 540.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SHR0302
CAS:1445987-21-2
SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity …
Formula:
C18H22N8O2S
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
414.48
Ref: TM-T9195
| 1mg | 160.00 € | ||
| 5mg | 393.00 € | ||
| 10mg | 620.00 € | ||
| 25mg | 1,035.00 € | ||
| 50mg | 1,483.00 € | ||
| 100mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 455.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
AG490
CAS:133550-30-8
AG490 inhibits EGFR (0.1 μM IC50), 135x >selective than ErbB2, blocks JAK2, spares Lyn, Lck, …
Formula:
C17H14N2O3
Purity:
98.6% - 99.39%
Color and Shape:
Yellow Solid
Molecular weight:
294.3
Ref: TM-T2600
| 10mg | 50.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 160.00 € | ||
| 500mg | 283.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Fedratinib hydrochloride hydrate
CAS:1374744-69-0
Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active …
Formula:
C27H40Cl2N6O4S
Purity:
98.96% - 99.46%
Color and Shape:
Solid
Molecular weight:
615.61
Ref: TM-T9251
| 5mg | 47.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 86.00 € | ||
| 50mg | 100.00 € | ||
| 100mg | 119.00 € | ||
| 200mg | 187.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
