JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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RO8191
CAS:691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Formula:
C14H5F6N5O
Purity:
98.85% - ≥98%
Color and Shape:
Solid
Molecular weight:
373.21
Ref: TM-T22142
| 1mg | 46.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 710.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ZM39923 hydrochloride
CAS:1021868-92-7
ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and …
Formula:
C23H25NO·HCl
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
367.91
Ref: TM-T6145
| 5mg | 59.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
JANEX-1
CAS:202475-60-3
JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.
Formula:
C16H15N3O3
Purity:
98% - 99.73%
Color and Shape:
Solid
Molecular weight:
297.31
Ref: TM-T2045
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 444.00 € | ||
| 100mg | 652.00 € | ||
| 500mg | 1,378.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Peficitinib
CAS:944118-01-8
Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
Formula:
C18H22N4O2
Purity:
98.67% - 99.4%
Color and Shape:
Solid
Molecular weight:
326.39
Ref: TM-T6933
| 2mg | 40.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 439.00 € | ||
| 200mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Protosappanin A
CAS:102036-28-2
Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV …
Formula:
C15H12O5
Purity:
100% - 99.42%
Color and Shape:
Solid
Molecular weight:
272.25
Ref: TM-TJS1779
| 1mg | 87.00 € | ||
| 5mg | 216.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 582.00 € | ||
| 50mg | 825.00 € | ||
| 100mg | 1,111.00 € | ||
| 1mL*10mM (DMSO) | 197.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Cerdulatinib
CAS:1198300-79-6
Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.
Formula:
C20H27N7O3S
Purity:
98.74% - 99.49%
Color and Shape:
Solid
Molecular weight:
445.54
Ref: TM-T2487
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 432.00 € | ||
| 200mg | 605.00 € | ||
| 500mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Upadacitinib
CAS:1310726-60-3
Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.
Formula:
C17H19F3N6O
Purity:
98.96% - 99.93%
Color and Shape:
Solid
Molecular weight:
380.37
Ref: TM-T7503
| 1mg | 47.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 130.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 434.00 € | ||
| 200mg | 662.00 € | ||
| 500mg | 1,169.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Momelotinib
CAS:1056634-68-4
Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT …
Formula:
C23H22N6O2
Purity:
97.47% - 99.56%
Color and Shape:
Solid
Molecular weight:
414.46
Ref: TM-T1849
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 406.00 € | ||
| 200mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
LFM-A13
CAS:244240-24-2
LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other …
Formula:
C11H8Br2N2O2
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
360
Ref: TM-T6217
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 167.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 398.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Itacitinib
CAS:1334298-90-6
Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic …
Formula:
C26H23F4N9O
Purity:
96.4% - 99.01%
Color and Shape:
Solid
Molecular weight:
553.51
Ref: TM-T3998
| 1mg | 49.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 780.00 € | ||
| 500mg | 1,549.00 € | ||
| 1mL*10mM (DMSO) | 137.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Tofacitinib
CAS:477600-75-2
Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of …
Formula:
C16H20N6O
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
312.37
Ref: TM-T6321
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 65.00 € | ||
| 50mg | 85.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 144.00 € | ||
| 500mg | 261.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Ruxolitinib
CAS:941678-49-5
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.
Formula:
C17H18N6
Purity:
100% - 99.99%
Color and Shape:
Solid
Molecular weight:
306.36
Ref: TM-T1829
| 5mg | 58.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 116.00 € | ||
| 100mg | 155.00 € | ||
| 200mg | 245.00 € | ||
| 500mg | 414.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Fosifidancitinib
CAS:1237168-58-9
Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.
Formula:
C21H21FN5O7P
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
505.39
Ref: TM-T38624
| 1mg | 87.00 € | ||
| 2mg | 124.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 284.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 867.00 € | ||
| 200mg | 1,159.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Oclacitinib maleate
CAS:1640292-55-2
Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with …
Formula:
C15H23N5O2S·C4H4O4
Purity:
99.17%
Color and Shape:
Solid
Molecular weight:
453.51
Ref: TM-T6914
| 1mg | 39.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Oclacitinib
CAS:1208319-26-9
Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not …
Formula:
C15H23N5O2S
Purity:
98% - 98.12%
Color and Shape:
White To Off-White Solid
Molecular weight:
337.44
Ref: TM-T2012
| 5mg | 47.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 274.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
AZD-1480
CAS:935666-88-9
AZD1480: JAK2 inhibitor, IC50 0.26 nM; selective vs Tyk2, JAK3; less on JAK1. Used in …
Formula:
C14H14ClFN8
Purity:
97.5% - 98.55%
Color and Shape:
Solid
Molecular weight:
348.77
Ref: TM-T3069
| 5mg | 57.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
JAK-IN-5 hydrochloride
CAS:2751323-21-2
JAK-IN-5 hydrochloride is a JAK inhibitor [1].
Formula:
C27H32ClFN6O
Color and Shape:
Liquid
Molecular weight:
511.03
Ref: TM-T11710L
| 25mg | 1,539.00 € | ||
| 50mg | 2,005.00 € | ||
| 100mg | 2,992.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
NVP-BSK805
CAS:1092499-93-8
NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
Formula:
C27H28F2N6O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
490.55
Ref: TM-T5049
| 1mg | 63.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 210.00 € | ||
| 25mg | 410.00 € |
Estimated delivery in United States, on Tuesday 6 May 2025
JAK3/BTK-IN-1
CAS:2674036-91-8
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 …
Formula:
C25H28N8O
Purity:
97.89%
Color and Shape:
Liquid
Molecular weight:
456.54
Ref: TM-T9814
| 1mg | 235.00 € | ||
| 5mg | 587.00 € | ||
| 10mg | 835.00 € | ||
| 25mg | 1,264.00 € | ||
| 50mg | 1,634.00 € | ||
| 100mg | 2,460.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
JAK-IN-28
CAS:2445500-22-9
JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of …
Formula:
C20H18ClN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
407.86
Ref: TM-T79116
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
