JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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JAK3-IN-1
CAS:1805787-93-2
JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune …
Formula:
C26H30ClN7O2
Color and Shape:
Solid
Molecular weight:
508.02
Ref: TM-T15607
| 5mg | 216.00 € | ||
| 25mg | 727.00 € | ||
| 50mg | 947.00 € | ||
| 100mg | 1,320.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
Lorpucitinib
CAS:2230282-02-5
Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal …
Formula:
C22H28N6O2
Purity:
99.72%
Color and Shape:
Liquid
Molecular weight:
408.5
Ref: TM-T62053
| 1mg | 216.00 € | ||
| 5mg | 543.00 € | ||
| 10mg | 868.00 € | ||
| 25mg | 1,644.00 € | ||
| 50mg | 2,650.00 € | ||
| 100mg | 3,581.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK1-IN-8
CAS:1973485-18-5
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Formula:
C22H23FN4O3S
Purity:
98.36%
Color and Shape:
Liquid
Molecular weight:
442.51
Ref: TM-T35899
| 5mg | 47.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 424.00 € | ||
| 200mg | 568.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
Izencitinib
CAS:2051918-33-1
Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative …
Formula:
C22H26N8
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
402.50
Ref: TM-T35898
| 1mg | 88.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 298.00 € | ||
| 25mg | 597.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,510.00 € | ||
| 200mg | 2,072.00 € | ||
| 1mL*10mM (DMSO) | 207.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK3i
CAS:1918238-72-8
JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T …
Formula:
C18H15FN4O3
Purity:
98.61% - 99.81%
Color and Shape:
Solid
Molecular weight:
354.34
Ref: TM-T27650
| 1mg | 333.00 € | ||
| 5mg | 787.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,510.00 € | ||
| 50mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 662.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK-IN-11
CAS:916742-11-5
JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the …
Formula:
C23H22FN5O4S
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
483.52
Ref: TM-T12549
| 1mg | 284.00 € | ||
| 5mg | 568.00 € | ||
| 10mg | 924.00 € | ||
| 25mg | 1,681.00 € | ||
| 50mg | 2,262.00 € | ||
| 1mL*10mM (DMSO) | 645.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK-IN-10
CAS:916741-98-5
JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye …
Formula:
C20H18FN5O3S
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
427.45
Ref: TM-T13571
| 1mg | 87.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 260.00 € | ||
| 25mg | 429.00 € | ||
| 50mg | 605.00 € | ||
| 100mg | 815.00 € | ||
| 500mg | 1,624.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK-STAT-IN-1
CAS:1236666-76-4
JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.
Formula:
C21H21N5O2
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
375.42
Ref: TM-T78607
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € | ||
| 100mg | 1,872.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
Momelotinib Mesylate
CAS:1056636-07-7
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity …
Formula:
C24H26N6O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
510.57
Ref: TM-T15037
| 25mg | 1,444.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JBJ-04-125-02
CAS:2060610-53-7
JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.
Formula:
C29H26FN5O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
543.61
Ref: TM-T11714
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
SD-1029
CAS:118372-34-2
SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation …
Formula:
C25H32Br2Cl2N2O3
Color and Shape:
Solid
Molecular weight:
639.25
Ref: TM-T24774
| 1mg | 120.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
Jaspamycin
CAS:22242-96-2
Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα.
Formula:
C12H12N4O5
Color and Shape:
Solid
Molecular weight:
292.25
Ref: TM-T11711
| 5mg | 283.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,293.00 € | ||
| 100mg | 1,768.00 € | ||
| 1mL*10mM (DMSO) | 303.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK-IN-30
CAS:2891469-99-9
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with …
Formula:
C19H26N8S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
398.53
Ref: TM-T79235
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK3/BTK-IN-2
CAS:2674036-93-0
JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:
C25H32N8O2
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
476.57
Ref: TM-T9813
| 1mg | 235.00 € | ||
| 5mg | 587.00 € | ||
| 10mg | 835.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK2-IN-9
CAS:2568842-26-0
Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 …
Formula:
C20H24N6O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
412.51
Ref: TM-T79581
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK1-IN-4
CAS:2091134-35-7
JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in …
Formula:
C26H32FN9O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
521.59
Ref: TM-T15606
| 25mg | 1,586.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,660.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
JAK-IN-27
CAS:2673176-36-6
JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS …
Formula:
C20H21F2N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
413.42
Ref: TM-T79110
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
JAK1-IN-11
CAS:2427608-43-1
JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations …
Formula:
C26H36N6O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
528.67
Ref: TM-T79079
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
JAK2-IN-4
CAS:1438284-00-4
JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM …
Formula:
C23H27N5O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
469.56
Ref: TM-T11708
| 25mg | 1,872.00 € | ||
| 50mg | 2,452.00 € | ||
| 100mg | 3,230.00 € |
Estimated delivery in United States, on Friday 27 Jun 2025
DPP
CAS:2668267-47-6
DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast …
Formula:
C36H40Cl2N2O10Pt
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
926.7
Ref: TM-T79608
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 27 Jun 2025
