JAK
JAK (Janus kinase) inhibitors are compounds that target the JAK-STAT signaling pathway, which is involved in cell growth, immune response, and angiogenesis. By inhibiting JAK, these compounds can reduce the signaling that leads to the formation of new blood vessels in tumors, thereby inhibiting tumor growth. JAK inhibitors are important in the treatment of cancers and inflammatory diseases. At CymitQuimica, we offer a diverse range of high-quality JAK inhibitors to support your research in oncology, immunology, and angiogenesis.
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Pyridone 6
CAS:457081-03-7
Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 …
Formula:
C18H16FN3O
Purity:
97.10% - 98.74%
Color and Shape:
Solid
Molecular weight:
309.34
Ref: TM-T3080
| 1mg | 81.00 € | ||
| 2mg | 105.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 648.00 € | ||
| 100mg | 918.00 € | ||
| 500mg | 1,838.00 € | ||
| 1mL*10mM (DMSO) | 176.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WHI-P97
CAS:211555-05-4
WHI-P97 is a rationally designed potent inhibitor of JAK-3.
Formula:
C16H13Br2N3O3
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
455.1
Ref: TM-T4657
| 5mg | 51.00 € | ||
| 10mg | 76.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 186.00 € | ||
| 100mg | 277.00 € | ||
| 200mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BD750
CAS:892686-59-8
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 …
Formula:
C14H13N3OS
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
271.34
Ref: TM-T8546
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 382.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Formula:
C16H13Cl2N3O2
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
350.2
Ref: TM-T22338
| 1mg | 60.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 611.00 € | ||
| 100mg | 852.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Deucravacitinib
CAS:1609392-27-9
Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.
Formula:
C20H19D3N8O3
Purity:
100% - 99.43%
Color and Shape:
Solid
Molecular weight:
425.46
Ref: TM-T14687
| 1mg | 69.00 € | ||
| 5mg | 149.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 625.00 € | ||
| 100mg | 892.00 € | ||
| 200mg | 1,205.00 € | ||
| 500mg | 1,784.00 € | ||
| 1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WHI-P154
CAS:211555-04-3
WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
Formula:
C16H14BrN3O3
Purity:
98% - 99.6%
Color and Shape:
Solid
Molecular weight:
376.2
Ref: TM-T1985
| 2mg | 46.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 532.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AT9283
CAS:896466-04-9
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, …
Formula:
C19H23N7O2
Purity:
99.87% - 99.98%
Color and Shape:
Solid
Molecular weight:
381.43
Ref: TM-T3068
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 488.00 € | ||
| 100mg | 711.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gandotinib
CAS:1229236-86-5
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).
Formula:
C23H25ClFN7O
Purity:
99.16% - 99.86%
Color and Shape:
Solid
Molecular weight:
469.94
Ref: TM-T2638
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 290.00 € | ||
| 100mg | 460.00 € | ||
| 500mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CEP-33779
CAS:1257704-57-6
CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.
Formula:
C24H26N6O2S
Purity:
98.81% - ≥95%
Color and Shape:
Solid
Molecular weight:
462.57
Ref: TM-T6122
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 372.00 € | ||
| 100mg | 553.00 € | ||
| 500mg | 1,194.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Filgotinib
CAS:1206161-97-8
Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and …
Formula:
C21H23N5O3S
Purity:
98.03% - ≥95%
Color and Shape:
Solid
Molecular weight:
425.5
Ref: TM-T1929
| 1mg | 38.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 241.00 € | ||
| 100mg | 318.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Baricitinib phosphate
CAS:1187595-84-1
Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.
Formula:
C16H20N7O6PS
Purity:
98.87% - 99.68%
Color and Shape:
Solid
Molecular weight:
469.41
Ref: TM-T2360
| 5mg | 47.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 113.00 € | ||
| 100mg | 142.00 € | ||
| 500mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.
Formula:
C16H14Br2ClN3O3
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
491.56
Ref: TM-T4657L
| 1mg | 41.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 194.00 € | ||
| 50mg | 267.00 € | ||
| 100mg | 381.00 € | ||
| 200mg | 542.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ritlecitinib
CAS:1792180-81-4
Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity …
Formula:
C15H19N5O
Purity:
98.82% - 99.92%
Color and Shape:
Solid
Molecular weight:
285.34
Ref: TM-T5382
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 485.00 € | ||
| 200mg | 690.00 € | ||
| 500mg | 1,047.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Abrocitinib
CAS:1622902-68-4
Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for …
Formula:
C14H21N5O2S
Purity:
99.09% - 99.91%
Color and Shape:
Solid
Molecular weight:
323.41
Ref: TM-TQ0037
| 1mg | 83.00 € | ||
| 2mg | 106.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 278.00 € | ||
| 25mg | 456.00 € | ||
| 50mg | 677.00 € | ||
| 100mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Atractylenolide I
CAS:73069-13-3
Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to …
Formula:
C15H18O2
Purity:
97.55%
Color and Shape:
Solid
Molecular weight:
230.3
Ref: TM-T5S0167
| 1mg | 42.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 414.00 € | ||
| 100mg | 579.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
XL019
CAS:945755-56-6
XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold …
Formula:
C25H28N6O2
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
444.53
Ref: TM-T3072
| 5mg | 74.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 515.00 € | ||
| 200mg | 439.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WP1066
CAS:857064-38-1
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in …
Formula:
C17H14BrN3O
Purity:
98.92% - 99.73%
Color and Shape:
Solid
Molecular weight:
356.22
Ref: TM-T2156
| 5mg | 52.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 293.00 € | ||
| 500mg | 714.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZ960
CAS:905586-69-8
AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).
Formula:
C18H16F2N6
Purity:
96.02% - 98.51%
Color and Shape:
Solid
Molecular weight:
354.36
Ref: TM-T6309
| 1mg | 77.00 € | ||
| 2mg | 94.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 534.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mollugin
CAS:55481-88-4
Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and …
Formula:
C17H16O4
Purity:
98.31% - ≥95%
Color and Shape:
Solid
Molecular weight:
284.31
Ref: TM-T3673
| 5mg | 46.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 276.00 € | ||
| 500mg | 681.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Prim-O-glucosylcimifugin
CAS:80681-45-4
Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion …
Formula:
C22H28O11
Purity:
99.47% - 99.92%
Color and Shape:
Solid
Molecular weight:
468.45
Ref: TM-T3805
| 1mg | 60.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 516.00 € | ||
| 100mg | 733.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
