JNK
JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.
Found 105 products of "JNK"
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SU3327
CAS:SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).Formula:C5H3N5O2S3Purity:98.39%Color and Shape:SolidMolecular weight:261.3Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormula:C13H8O3Purity:99.45%Color and Shape:SolidMolecular weight:212.2JNK-IN-13
CAS:JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.
Formula:C13H7ClN4SPurity:98.74%Color and Shape:SolidMolecular weight:286.74Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.99%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77NBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Formula:C12H15N3O4SPurity:97.38%Color and Shape:SolidMolecular weight:297.33Metacetamol
CAS:Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.Formula:C8H9NO2Purity:99.76% - 99.90%Color and Shape:Physical Description Light Gray Solid (Ntp 1992)Molecular weight:151.16Tanzisertib
CAS:Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Formula:C21H23F3N6O2Purity:98.66% - 99.28%Color and Shape:SolidMolecular weight:448.44Ref: TM-T14895
1mg39.00€5mg93.00€10mg138.00€25mg268.00€50mg530.00€100mg705.00€200mg973.00€1mL*10mM (DMSO)92.00€Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.
Formula:C11H12Cl2N2O5Purity:99.6% - 99.84%Color and Shape:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidMolecular weight:323.13Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.
Formula:C17H16F6N2OPurity:99.89%Color and Shape:SolidMolecular weight:378.31SP 600125, negative control
CAS:SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125.
Formula:C15H10N2OPurity:≥98%Color and Shape:SolidMolecular weight:234.25JNK-IN-18
JNK-IN-18 (compound 23b) is a potent inhibitor of JNK1, boasting an IC50 of 2 nM. It demonstrates superior efficacy when compared to its IC50 values of 125 nM for JNK2 and 98 nM for BRAF(V600E).Color and Shape:Odour SolidAS601245.2TFA (345987-15-7 free base)
CAS:AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3,Formula:C24H18F6N6O4SPurity:98%Color and Shape:SoildMolecular weight:600.50JNK-1-IN-3
CAS:JNK-1-IN-3 (Compound 9e) downregulates JNK1 and phosphorylated JNK1, reduces c-Jun and c-Fos expression in tumours, and restores p53 activity.Formula:C19H17FN4O3Purity:97.551%Color and Shape:SolidMolecular weight:368.36D-JBD19
CAS:D-JBD19 is a non-permeable peptide with neuroprotective effects.Formula:C99H164N32O28Purity:98%Color and Shape:SolidMolecular weight:2250.597JTP10-△-TATi TFA
JTP10-△-TATi TFA is a selective inhibitor of JNK2 peptide (IC50: 92 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.Formula:C120H213F3N48O28Purity:98%Color and Shape:SolidMolecular weight:2833.28L-JNKI-1
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.Formula:C164H286N66O40Purity:98%Color and Shape:SolidMolecular weight:3822.44JNK3 inhibitor-7
Potent, oral JNK3 inhibitor-7 crosses blood-brain barrier, IC50: 53 nM (JNK3), offers neuroprotection, potential in AD research.Formula:C32H31N7O3Color and Shape:SolidMolecular weight:561.63OVA-E1 peptide
CAS:OVA-E1 peptide, as SIINFEKL variant, triggers similar p38/JNK activation in mutant and normal thymocytes.Formula:C47H76N10O14Color and Shape:SolidMolecular weight:1005.181MAP4K4-IN-6
MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor with an IC50 of 80 nM. It reduces the phosphorylation of c-Jun and exhibits neuroprotective effects. Additionally, MAP4K4-IN-6 enhances the vitality of motor neurons and can be utilized in the study of amyotrophic lateral sclerosis (ALS).Color and Shape:Odour SolidJNK3 inhibitor-8
JNK3 inhibitor-8: potent, selective, oral, BBB-penetrating, IC50: JNK3=21 nM, JNK2=2203 nM, JNK1>10,000 nM; potential in Alzheimer's research.Formula:C32H30FN7O3Color and Shape:SolidMolecular weight:579.62
