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JNK

JNK

JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.

Found 96 products of "JNK"

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  • SU3327
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    SU3327

    CAS:
    <p>SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).</p>
    Formula:C5H3N5O2S3
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:261.3

    Ref: TM-T13018

  • Urolithin B
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    Urolithin B

    CAS:
    <p>Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical</p>
    Formula:C13H8O3
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:212.2

    Ref: TM-T13265

  • Mefloquine
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    Mefloquine

    CAS:
    <p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>
    Formula:C17H16F6N2O
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:378.31

    Ref: TM-T0860L

  • Tanzisertib
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    Tanzisertib

    CAS:
    <p>Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.</p>
    Formula:C21H23F3N6O2
    Purity:98.66% - 99.28%
    Color and Shape:Solid
    Molecular weight:448.44

    Ref: TM-T14895

  • NBDHEX
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    NBDHEX

    CAS:
    <p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>
    Formula:C12H15N3O4S
    Purity:97.38%
    Color and Shape:Solid
    Molecular weight:297.33

    Ref: TM-T12189

  • Metacetamol
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    Metacetamol

    CAS:
    <p>Metacetamol, a non-toxic acetaminophen derivative, is an OTC analgesic/antipyretic and synthesis intermediate.</p>
    Formula:C8H9NO2
    Purity:99.76% - 99.90%
    Color and Shape:Physical Description Light Gray Solid (Ntp 1992)
    Molecular weight:151.16

    Ref: TM-T0914

  • Mefloquine hydrochloride
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    Mefloquine hydrochloride

    CAS:
    <p>Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.</p>
    Formula:C17H17ClF6N2O
    Purity:99% - 99.74%
    Color and Shape:Off-White To Yellow Solid
    Molecular weight:414.77

    Ref: TM-T0860

  • JNK-IN-13
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    JNK-IN-13

    CAS:
    <p>JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in the study of diabetes, inflammation, and neurological disorders.</p>
    Formula:C13H7ClN4S
    Purity:98.74%
    Color and Shape:Solid
    Molecular weight:286.74

    Ref: TM-T77694

  • Chloramphenicol
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    Chloramphenicol

    CAS:
    <p>Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.</p>
    Formula:C11H12Cl2N2O5
    Purity:99.6% - 99.84%
    Color and Shape:Needles Or Elongated Plates From Water Or Ethylene Dichloride Solid
    Molecular weight:323.13

    Ref: TM-T1205

  • SP 600125, negative control
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    SP 600125, negative control

    CAS:
    <p>SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125.</p>
    Formula:C15H10N2O
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:234.25

    Ref: TM-T38260

  • CymitQuimica logo
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    JNK-IN-18

    <p>JNK-IN-18 (compound 23b) is a potent inhibitor of JNK1, boasting an IC50 of 2 nM. It demonstrates superior efficacy when compared to its IC50 values of 125 nM for JNK2 and 98 nM for BRAF(V600E).</p>
    Color and Shape:Odour Solid

    Ref: TM-T200732

  • AS601245.2TFA (345987-15-7 free base)
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    AS601245.2TFA (345987-15-7 free base)

    CAS:
    <p>AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3,</p>
    Formula:C24H18F6N6O4S
    Purity:98%
    Color and Shape:Soild
    Molecular weight:600.50

    Ref: TM-T8661

  • JNK-1-IN-3
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    JNK-1-IN-3

    CAS:
    <p>JNK-1-IN-3 (Compound 9e) downregulates JNK1 and phosphorylated JNK1, reduces c-Jun and c-Fos expression in tumours, and restores p53 activity.</p>
    Formula:C19H17FN4O3
    Purity:97.551%
    Color and Shape:Solid
    Molecular weight:368.36

    Ref: TM-T200221

  • D-JBD19
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    D-JBD19

    CAS:
    <p>D-JBD19 is a non-permeable peptide with neuroprotective effects.</p>
    Formula:C99H164N32O28
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2250.597

    Ref: TM-TP2162

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    L-JNKI-1

    <p>L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.</p>
    Formula:C164H286N66O40
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3822.44

    Ref: TM-TP1353

  • CymitQuimica logo
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    JNK3 inhibitor-7

    <p>Potent, oral JNK3 inhibitor-7 crosses blood-brain barrier, IC50: 53 nM (JNK3), offers neuroprotection, potential in AD research.</p>
    Formula:C32H31N7O3
    Color and Shape:Solid
    Molecular weight:561.63

    Ref: TM-T74817

  • OVA-E1 peptide
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    OVA-E1 peptide

    CAS:
    <p>OVA-E1 peptide, as SIINFEKL variant, triggers similar p38/JNK activation in mutant and normal thymocytes.</p>
    Formula:C47H76N10O14
    Color and Shape:Solid
    Molecular weight:1005.181

    Ref: TM-T39017

  • CymitQuimica logo
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    MAP4K4-IN-6

    <p>MAP4K4-IN-6 (Compound 15f) is a MAP4K4 inhibitor with an IC50 of 80 nM. It reduces the phosphorylation of c-Jun and exhibits neuroprotective effects. Additionally, MAP4K4-IN-6 enhances the vitality of motor neurons and can be utilized in the study of amyotrophic lateral sclerosis (ALS).</p>
    Color and Shape:Odour Solid

    Ref: TM-T200733

  • CymitQuimica logo
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    JNK3 inhibitor-8

    <p>JNK3 inhibitor-8: potent, selective, oral, BBB-penetrating, IC50: JNK3=21 nM, JNK2=2203 nM, JNK1&gt;10,000 nM; potential in Alzheimer's research.</p>
    Formula:C32H30FN7O3
    Color and Shape:Solid
    Molecular weight:579.62

    Ref: TM-T74818

  • CC-401
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    CC-401

    CAS:
    <p>CC-401 is a specific inhibitor of JNK (Ki: 25-50nM).</p>
    Formula:C22H24N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:388.47

    Ref: TM-T22639