JNK
JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.
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Polyphyllin I
CAS:50773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression …
Formula:
C44H70O16
Purity:
98% - 99.5%
Color and Shape:
Solid
Molecular weight:
855.02
Ref: TM-T3895
| 5mg | 57.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 226.00 € | ||
| 100mg | 378.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Pamapimod
CAS:449811-01-2
Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.
Formula:
C19H20F2N4O4
Purity:
97.63% - 99.99%
Color and Shape:
Solid
Molecular weight:
406.38
Ref: TM-T6927
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 378.00 € | ||
| 50mg | 605.00 € | ||
| 100mg | 852.00 € | ||
| 500mg | 1,700.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Taurochenodeoxycholic Acid
CAS:516-35-8
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
Formula:
C26H45NO6S
Purity:
99.69% - 99.86%
Color and Shape:
Solid
Molecular weight:
499.7
Ref: TM-T2A2481
| 25mg | 47.00 € | ||
| 50mg | 65.00 € | ||
| 100mg | 87.00 € | ||
| 200mg | 126.00 € | ||
| 500mg | 208.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Friday 2 May 2025
JNK Inhibitor VIII
CAS:894804-07-0
JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase …
Formula:
C18H20N4O4
Purity:
98.93%
Color and Shape:
Solid
Molecular weight:
356.38
Ref: TM-T7677
| 1mg | 60.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 490.00 € | ||
| 100mg | 700.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Isovitexin
CAS:38953-85-4
1.
Formula:
C21H20O10
Purity:
98.24% - 99.79%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-T6S1371
| 1mg | 52.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 411.00 € | ||
| 100mg | 597.00 € | ||
| 500mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Friday 2 May 2025
IQ-3
CAS:312538-03-7
IQ3 inhibits JNK3 (Kd 66 nM), JNK1/2, NF-κB/AP1 in THP1-Blue cells (IC50 1.4 μM), and …
Formula:
C20H11N3O3
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
341.32
Ref: TM-T8477
| 1mg | 40.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 522.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Indirubin-3′-oxime
CAS:667463-82-3
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role …
Formula:
C16H11N3O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
277.28
Ref: TM-T9138
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 562.00 € | ||
| 200mg | 815.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Friday 2 May 2025
IQ-1S free acid
CAS:23146-22-7
IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits …
Formula:
C15H9N3O
Purity:
97.92% - 99.05%
Color and Shape:
Solid
Molecular weight:
247.25
Ref: TM-T3627
| 5mg | 47.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 304.00 € | ||
| 200mg | 454.00 € | ||
| 500mg | 733.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Friday 2 May 2025
AS601245
CAS:345987-15-7
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.
Formula:
C20H16N6S
Purity:
98% - 99.02%
Color and Shape:
Solid
Molecular weight:
372.45
Ref: TM-T2343
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 605.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Taurochenodeoxycholic acid sodium
CAS:6009-98-9
Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).
Formula:
C26H44NNaO6S
Purity:
98.23% - 99.45%
Color and Shape:
White To Off-White Powder
Molecular weight:
521.68
Ref: TM-TN2215
| 100mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Fasudil hydrochloride
CAS:105628-07-7
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki …
Formula:
C14H18ClN3O2S
Purity:
100% - ≥95%
Color and Shape:
White Solid
Molecular weight:
327.83
Ref: TM-T3060
| 50mg | 42.00 € | ||
| 100mg | 49.00 € | ||
| 200mg | 74.00 € | ||
| 500mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 2 May 2025
CC-90001
CAS:1403859-14-2
CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over …
Formula:
C16H27N5O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
321.42
Ref: TM-T9688
| 1mg | 157.00 € | ||
| 5mg | 323.00 € | ||
| 10mg | 510.00 € | ||
| 25mg | 825.00 € | ||
| 50mg | 1,130.00 € | ||
| 100mg | 1,510.00 € | ||
| 1mL*10mM (DMSO) | 354.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Esculentoside H
CAS:66656-92-6
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H …
Formula:
C48H76O21
Purity:
98.04% - 99.3%
Color and Shape:
Solid
Molecular weight:
989.1
Ref: TM-T3S1641
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 329.00 € | ||
| 50mg | 490.00 € | ||
| 100mg | 700.00 € | ||
| 500mg | 1,406.00 € |
Estimated delivery in United States, on Friday 2 May 2025
TCS JNK 5a
CAS:312917-14-9
TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
Formula:
C20H16N2OS
Purity:
97.88% - 99.5%
Color and Shape:
Solid
Molecular weight:
332.42
Ref: TM-T2234
| 5mg | 47.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 283.00 € | ||
| 500mg | 692.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Ginsenoside Re
CAS:52286-59-6
Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.
Formula:
C48H82O18
Purity:
100% - 99.78%
Color and Shape:
White Powder
Molecular weight:
947.15
Ref: TM-T2872
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 145.00 € | ||
| 100mg | 207.00 € | ||
| 500mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Juglanin
CAS:5041-67-8
Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis …
Formula:
C20H18O10
Purity:
98.8% - 99.33%
Color and Shape:
Solid
Molecular weight:
418.35
Ref: TM-TQ0089
| 1mg | 111.00 € | ||
| 5mg | 274.00 € | ||
| 10mg | 406.00 € | ||
| 25mg | 662.00 € | ||
| 50mg | 919.00 € |
Estimated delivery in United States, on Friday 2 May 2025
IMM-H007
CAS:1221412-23-2
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
Formula:
C22H23N5O8
Purity:
97.73%
Color and Shape:
Solid
Molecular weight:
485.45
Ref: TM-T9010
| 1mg | 40.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 320.00 € | ||
| 100mg | 434.00 € | ||
| 200mg | 602.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Friday 2 May 2025
WHI-P258
CAS:21561-09-1
WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.
Formula:
C16H15N3O2
Purity:
99.64% - 99.95%
Color and Shape:
Solid
Molecular weight:
281.31
Ref: TM-T2035
| 5mg | 34.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 144.00 € | ||
| 100mg | 239.00 € | ||
| 200mg | 349.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Friday 2 May 2025
JNK-IN-11
CAS:676594-38-0
JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.
Formula:
C12H11NO3S2
Purity:
98.82%
Color and Shape:
Liquid
Molecular weight:
281.35
Ref: TM-T60534
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 592.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
J30-8
CAS:2366255-71-0
J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used …
Formula:
C17H9ClFN3O2S
Purity:
99.90%
Color and Shape:
Solid
Molecular weight:
373.79
Ref: TM-T11702
| 1mg | 38.00 € |
Estimated delivery in United States, on Friday 13 Jun 2025
