
JNK
JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.
Found 96 products of "JNK"
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IQ-1S free acid
CAS:<p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>Formula:C15H9N3OPurity:97.92% - 99.05%Color and Shape:SolidMolecular weight:247.25Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83CC-90001
CAS:<p>CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.</p>Formula:C16H27N5O2Purity:99.96%Color and Shape:SolidMolecular weight:321.42Esculentoside H
CAS:<p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1TCS JNK 5a
CAS:<p>TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).</p>Formula:C20H16N2OSPurity:99.22% - 99.51%Color and Shape:SolidMolecular weight:332.42Ginsenoside Re
CAS:<p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>Formula:C48H82O18Purity:99.12% - >99.99%Color and Shape:White PowderMolecular weight:947.15Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Formula:C20H18O10Purity:98.8% - 99.33%Color and Shape:SolidMolecular weight:418.35Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.65Sesamolin
CAS:<p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Pamapimod
CAS:<p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>Formula:C19H20F2N4O4Purity:99.52% - 99.99%Color and Shape:SolidMolecular weight:406.38SX 011
CAS:<p>SX 011 is a p38α inhibitor.</p>Formula:C26H27ClFN3O3Purity:98%Color and Shape:SolidMolecular weight:483.96TOPK-p38/JNK-IN-1
CAS:<p>TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO</p>Formula:C17H15F3N2O4Color and Shape:SolidMolecular weight:368.31J30-8
CAS:<p>J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used to study neurodegenerative diseases such as Alzheimer's disease.</p>Formula:C17H9ClFN3O2SPurity:99.90%Color and Shape:SolidMolecular weight:373.79JNK3 inhibitor-4
CAS:<p>JNK3 inhibitor-4: potent, selective JNK3 blocker (IC50=1.0nM), neuroprotective, BBB-permeable.</p>Formula:C28H27N7OColor and Shape:SolidMolecular weight:477.56JNK-1-IN-1
CAS:<p>JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM.</p>Formula:C24H22N6SColor and Shape:SolidMolecular weight:426.54SR 3576
CAS:<p>JNK3 inhibitor, potent and selective</p>Formula:C27H27N5O5Purity:98%Color and Shape:SolidMolecular weight:501.53SR-3306
CAS:<p>SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values of 67 nM, 283 nM, 159 nM.Cost-effective and quality-assured.</p>Formula:C28H26N8OPurity:99.38% - 99.71%Color and Shape:SolidMolecular weight:490.56SR-3737
CAS:<p>SR-3737 is potent both JNK3 and p38 inhibitor.</p>Formula:C29H25FN4O4Purity:98%Color and Shape:SolidMolecular weight:512.53BSJ-04-122
CAS:<p>BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM & 181 nM, used in cancer research.</p>Formula:C15H12ClN5OPurity:97.61%Color and Shape:SolidMolecular weight:313.74
