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JNK

JNK

JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.

Found 96 products of "JNK"

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  • IQ-1S free acid

    CAS:
    <p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>
    Formula:C15H9N3O
    Purity:97.92% - 99.05%
    Color and Shape:Solid
    Molecular weight:247.25
  • Taurochenodeoxycholic acid sodium

    CAS:
    <p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>
    Formula:C26H44NNaO6S
    Purity:98.23% - 99.45%
    Color and Shape:White To Off-White Powder
    Molecular weight:521.68
  • Fasudil hydrochloride

    CAS:
    <p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>
    Formula:C14H18ClN3O2S
    Purity:99.54% - ≥95%
    Color and Shape:White Solid
    Molecular weight:327.83
  • CC-90001

    CAS:
    <p>CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.</p>
    Formula:C16H27N5O2
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:321.42
  • Esculentoside H

    CAS:
    <p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>
    Formula:C48H76O21
    Purity:98.04% - 99.3%
    Color and Shape:Solid
    Molecular weight:989.1
  • TCS JNK 5a

    CAS:
    <p>TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).</p>
    Formula:C20H16N2OS
    Purity:99.22% - 99.51%
    Color and Shape:Solid
    Molecular weight:332.42
  • Ginsenoside Re

    CAS:
    <p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>
    Formula:C48H82O18
    Purity:99.12% - >99.99%
    Color and Shape:White Powder
    Molecular weight:947.15
  • Juglanin

    CAS:
    <p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>
    Formula:C20H18O10
    Purity:98.8% - 99.33%
    Color and Shape:Solid
    Molecular weight:418.35
  • Tomatidine

    CAS:
    <p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>
    Formula:C27H45NO2
    Purity:99.94% - 99.98%
    Color and Shape:Solid
    Molecular weight:415.65
  • Sesamolin

    CAS:
    <p>Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.</p>
    Formula:C20H18O7
    Purity:98.77% - 99.04%
    Color and Shape:Solid
    Molecular weight:370.35
  • Pamapimod

    CAS:
    <p>Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.</p>
    Formula:C19H20F2N4O4
    Purity:99.52% - 99.99%
    Color and Shape:Solid
    Molecular weight:406.38
  • SX 011

    CAS:
    <p>SX 011 is a p38α inhibitor.</p>
    Formula:C26H27ClFN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:483.96
  • TOPK-p38/JNK-IN-1

    CAS:
    <p>TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO</p>
    Formula:C17H15F3N2O4
    Color and Shape:Solid
    Molecular weight:368.31
  • J30-8

    CAS:
    <p>J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used to study neurodegenerative diseases such as Alzheimer's disease.</p>
    Formula:C17H9ClFN3O2S
    Purity:99.90%
    Color and Shape:Solid
    Molecular weight:373.79
  • JNK3 inhibitor-4

    CAS:
    <p>JNK3 inhibitor-4: potent, selective JNK3 blocker (IC50=1.0nM), neuroprotective, BBB-permeable.</p>
    Formula:C28H27N7O
    Color and Shape:Solid
    Molecular weight:477.56
  • JNK-1-IN-1

    CAS:
    <p>JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM.</p>
    Formula:C24H22N6S
    Color and Shape:Solid
    Molecular weight:426.54
  • SR 3576

    CAS:
    <p>JNK3 inhibitor, potent and selective</p>
    Formula:C27H27N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:501.53
  • SR-3306

    CAS:
    <p>SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values ​​of 67 nM, 283 nM, 159 nM.Cost-effective and quality-assured.</p>
    Formula:C28H26N8O
    Purity:99.38% - 99.71%
    Color and Shape:Solid
    Molecular weight:490.56
  • SR-3737

    CAS:
    <p>SR-3737 is potent both JNK3 and p38 inhibitor.</p>
    Formula:C29H25FN4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:512.53
  • BSJ-04-122

    CAS:
    <p>BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM &amp; 181 nM, used in cancer research.</p>
    Formula:C15H12ClN5O
    Purity:97.61%
    Color and Shape:Solid
    Molecular weight:313.74