JNK
JNKs are a subgroup of the MAPK family that respond to stress stimuli, such as cytokines, ultraviolet irradiation, and heat shock, and are involved in controlling apoptosis, inflammation, and immune responses. JNK signaling is crucial for the regulation of cellular stress responses and has been implicated in various diseases, including neurodegenerative disorders, cancer, and inflammatory conditions. At CymitQuimica, we provide a range of JNK pathway modulators to support your research in stress signaling, apoptosis, and disease pathology.
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DB07268
CAS:929007-72-7
DB07268 is a potent and selective JNK1 inhibitor.
Formula:
C17H15N5O2
Purity:
98.2% - 98.91%
Color and Shape:
Solid
Molecular weight:
321.33
Ref: TM-T3200
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 618.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
SP600125
CAS:129-56-6
SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 …
Formula:
C14H8N2O
Purity:
97.63% - 99.58%
Color and Shape:
Solid
Molecular weight:
220.23
Ref: TM-T3109
| 10mg | 48.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 80.00 € | ||
| 200mg | 90.00 € | ||
| 500mg | 144.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
BI-78D3
CAS:883065-90-5
BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays >100 fold …
Formula:
C13H9N5O5S2
Purity:
100% - 97.89%
Color and Shape:
Solid
Molecular weight:
379.37
Ref: TM-T6784
| 2mg | 38.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 401.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Anisomycin
CAS:22862-76-6
Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.
Formula:
C14H19NO4
Purity:
98.87% - 99.81%
Color and Shape:
White Crystalline Solid
Molecular weight:
265.3
Ref: TM-T6758
| 10mg | 55.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 160.00 € | ||
| 200mg | 215.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Loureirin B
CAS:119425-90-0
Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.
Formula:
C18H20O5
Purity:
99.33% - 99.86%
Color and Shape:
Solid
Molecular weight:
316.35
Ref: TM-T3876
| 1mg | 52.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 604.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
TOMATIDINE HYDROCHLORIDE
CAS:6192-62-7
Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not …
Formula:
C27H46ClNO2
Purity:
99.75% - ≥95%
Color and Shape:
Solid
Molecular weight:
452.11
Ref: TM-T4592
| 5mg | 49.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Actein
CAS:18642-44-9
Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and …
Formula:
C37H56O11
Purity:
≥98%
Color and Shape:
Brown Powder
Molecular weight:
676.83
Ref: TM-T7190
| 1mg | 142.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 460.00 € | ||
| 25mg | 736.00 € | ||
| 50mg | 994.00 € | ||
| 1mL*10mM (DMSO) | 415.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Polyphyllin I
CAS:50773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression …
Formula:
C44H70O16
Purity:
98% - 99.5%
Color and Shape:
Solid
Molecular weight:
855.02
Ref: TM-T3895
| 5mg | 56.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 369.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Ezatiostat hydrochloride
CAS:286942-97-0
Ezatiostat HCl (TLK199) inhibits glutathione S-transferase, GSTP1-1 specifically, and may treat cytopenias.
Formula:
C27H36ClN3O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
566.11
Ref: TM-T22776
| 2mg | 58.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 515.00 € | ||
| 200mg | 771.00 € | ||
| 500mg | 1,158.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Guggulsterone
CAS:95975-55-6
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
Formula:
C21H28O2
Purity:
99.40%
Color and Shape:
Light Yellow Powder
Molecular weight:
312.45
Ref: TM-T5574
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 399.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
JNK-IN-7
CAS:1408064-71-0
JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM).
Formula:
C28H27N7O2
Purity:
99.53% - 99.58%
Color and Shape:
Solid
Molecular weight:
493.56
Ref: TM-T3598
| 1mg | 96.00 € | ||
| 2mg | 155.00 € | ||
| 5mg | 221.00 € | ||
| 10mg | 285.00 € | ||
| 25mg | 514.00 € | ||
| 50mg | 736.00 € | ||
| 100mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 244.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
CC-401 Hydrochloride
CAS:1438391-30-0
CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) …
Formula:
C22H25ClN6O
Purity:
99.53% - ≥95%
Color and Shape:
Solid
Molecular weight:
424.93
Ref: TM-T5833
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 470.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Bentamapimod
CAS:848344-36-5
Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.
Formula:
C25H23N5O2S
Purity:
95.21% - 99.92%
Color and Shape:
Solid
Molecular weight:
457.55
Ref: TM-T2675
| 1g | 2,033.00 € | ||
| 2g | 2,739.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 159.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 344.00 € | ||
| 500mg | 1,131.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Astragaloside IV
CAS:84687-43-4
Astragaloside IV suppresses ERK1/2, JNK, MMP-2/9 in breast cancer; inhibits adenovirus and protects cardiovascular, immune, …
Formula:
C41H68O14
Purity:
99% - 99.84%
Color and Shape:
Hydroscopic Brown Or Yellow Powder
Molecular weight:
784.97
Ref: TM-T2973
| 5mg | 38.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 198.00 € | ||
| 500mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
JNK-IN-8
CAS:1410880-22-6
JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).
Formula:
C29H29N7O2
Purity:
100% - 99.24%
Color and Shape:
Solid
Molecular weight:
507.59
Ref: TM-T2668
| 2mg | 46.00 € | ||
| 5mg | 75.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 340.00 € | ||
| 100mg | 498.00 € | ||
| 200mg | 707.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
JNK-IN-11
CAS:676594-38-0
JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.
Formula:
C12H11NO3S2
Purity:
98.82%
Color and Shape:
Liquid
Molecular weight:
281.35
Ref: TM-T60534
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 578.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
SR-3306
CAS:1128096-91-2
SR-3306 is a brain-penetrant and selective pan-JNK (JNK1/2/3) inhibitor with IC50 values of 67 nM, …
Formula:
C28H26N8O
Purity:
99.50% - 99.81%
Color and Shape:
Solid
Molecular weight:
490.56
Ref: TM-T16927
| 1mg | 52.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 862.00 € | ||
| 500mg | 1,726.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
BSJ-04-122
CAS:2513289-74-0
BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM & 181 nM, used in cancer research.
Formula:
C15H12ClN5O
Purity:
97.58%
Color and Shape:
Odour Color
Molecular weight:
313.74
Ref: TM-T73182
| 1mg | 41.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 581.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
J30-8
CAS:2366255-71-0
J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used …
Formula:
C17H9ClFN3O2S
Purity:
99.90%
Color and Shape:
Solid
Molecular weight:
373.79
Ref: TM-T11702
| 1mg | 38.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
JAK2/FLT3-IN-1
CAS:2387765-27-5
Potent, orally active JAK2/FLT3-IN-1: Anti-cancer, dual JAK2/FLT3 inhibitor with low IC50s for JAK2/FLT3/JAK1/JAK3.
Formula:
C25H34FN7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
467.58
Ref: TM-T11707
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Monday 27 Jan 2025
