cAMP
cAMP is a second messenger important in many biological processes, including the regulation of metabolism, gene expression, and cell growth. In the MAPK signaling pathway, cAMP can modulate the activity of various kinases, including PKA, which in turn influences the MAPK cascade. Dysregulation of cAMP signaling is implicated in various diseases, including cancer and cardiovascular disorders. At CymitQuimica, we offer a variety of cAMP modulators to support your research in signal transduction, metabolism, and disease pathology.
Found 47 products of "cAMP"
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HJC0197
CAS:<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Formula:C19H21N3OSPurity:98.05%Color and Shape:SolidMolecular weight:339.45Bithionol
CAS:<p>Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to</p>Formula:C12H6Cl4O2SPurity:99.04%Color and Shape:White Or Grayish-White Crystalline Powder Phenolic Odor (Ntp 1992)Molecular weight:356.05CE3F4
CAS:<p>CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively).</p>Formula:C11H10Br2FNOPurity:97.15% - 98.06%Color and Shape:SolidMolecular weight:351.01Bucladesine sodium
CAS:<p>Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.</p>Formula:C18H23N5NaO8PPurity:96.56% - 99.76%Color and Shape:White PowderMolecular weight:491.37A-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22ESI-05
CAS:<p>ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.</p>Formula:C16H18O2SPurity:97.22%Color and Shape:SolidMolecular weight:274.38JNJ-39758979
CAS:<p>JNJ-39758979: selective H4 receptor antagonist, Kis 12.5/5.3/25 nM (human/mouse/monkey), blocks histamine cAMP inhibition (pA2 7.9).</p>Formula:C11H19N5Purity:98.33% - 99.62%Color and Shape:SolidMolecular weight:221.3MR-L2
CAS:<p>MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).</p>Formula:C19H16Cl3FN4OPurity:98.09% - 98.94%Color and Shape:SolidMolecular weight:441.71Mirabegron
CAS:<p>Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.</p>Formula:C21H24N4O2SPurity:99.64%Color and Shape:Light Yellow To Yellow SolidMolecular weight:396.51Adenosine 3'-monophosphate (sodium salt hydrate)
<p>Adenosine 3'-monophosphate (sodium salt hydrate) (3'-AMP) is a nucleotide and cAMP-generating agonist that elevates cAMP levels in NG108-15 cells.</p>Formula:C10H15N5NaO8PColor and Shape:SolidMolecular weight:387.22MRS-1706
CAS:<p>MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.</p>Formula:C27H29N5O5Purity:99.00%Color and Shape:SolidMolecular weight:503.55BC 11-38
CAS:<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Formula:C15H16N2OS2Purity:98.95% - 99.28%Color and Shape:SolidMolecular weight:304.432-PCCA hydrochloride
CAS:<p>2-PCCA hydrochloride, a racemate, is a potent and selective GPR88 receptor agonist showing inhibition of GPR88-mediated cAMP production in HEK293 cells with an</p>Formula:C30H39Cl2N3OPurity:97.54% - 99.36%Color and Shape:SoildMolecular weight:528.56OX04528
CAS:<p>OX04528 is an orally active and potent GPR84 biased agonist.OX04528 inhibits cAMP signaling and may be useful in cancer research.</p>Formula:C16H13F6NO2Purity:99.74%Color and Shape:SoildMolecular weight:365.27GLP-1R modulator L7-028
CAS:<p>GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.</p>Formula:C24H28N2O3Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:392.49Anti-Cathelicidin/Camp Polyclonal Antibody
<p>Antibody Type: Rabbit Polyclonal<br><br>Application: IHC-P,IHC-Fr,ICC/IF,IF,ELISA<br><br>Reactivity: (predicted:Mouse,Rat)</p>Color and Shape:LiquidMolecular weight:Theoretical: 19 kDa.Taprenepag
CAS:<p>Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).</p>Formula:C24H22N4O5SPurity:98.89% - 99.15%Color and Shape:SolidMolecular weight:478.52PSN 375963
CAS:<p>PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.</p>Formula:C17H23N3OPurity:99.63%Color and Shape:SolidMolecular weight:285.38Ro 20-1724
CAS:<p>Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1</p>Formula:C15H22N2O3Purity:98.82% - 99.79%Color and Shape:SolidMolecular weight:278.35(S)-(+)-Rolipram
CAS:<p>(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the</p>Formula:C16H21NO3Purity:99.14%Color and Shape:SolidMolecular weight:275.34Cyclic AMP
CAS:<p>cAMP and vitamin C treat viral myocarditis in children, enhancing cardiac and immune functions.</p>Formula:C10H12N5O6PPurity:98.01% - >99.99%Color and Shape:SolidMolecular weight:329.21SAX-187
CAS:<p>SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.</p>Formula:C15H13ClN4O2S2Purity:97.82% - 98%Color and Shape:SolidMolecular weight:380.87ESI-09
CAS:<p>ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 μM, respectively.</p>Formula:C16H15ClN4O2Purity:97.24% - 99.57%Color and Shape:SolidMolecular weight:330.77Glaucine
CAS:<p>Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.</p>Formula:C21H25NO4Purity:99.42% - 99.56%Color and Shape:SolidMolecular weight:355.43RS-25344 hydrochloride
CAS:<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Formula:C19H14ClN5O4Purity:99.25%Color and Shape:SolidMolecular weight:411.8Setipiprant
CAS:<p>Setipiprant (ACT-129968) is an oral CRTH2 antagonist for asthma/allergy, targeting PGD2-induced inflammation (IC50: 6.0 nM).</p>Formula:C24H19FN2O3Purity:99.16%Color and Shape:SolidMolecular weight:402.42Piclamilast
CAS:<p>Piclamilast (RP 73401) is a PDE4 inhibitor.</p>Formula:C18H18Cl2N2O3Purity:98.28% - 99.57%Color and Shape:SolidMolecular weight:381.25Pinoresinol 4-O-β-D-glucopyranoside
CAS:<p>(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia.</p>Formula:C26H32O11Purity:99.32% - >99.99%Color and Shape:SolidMolecular weight:520.53Forskolin
CAS:<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Formula:C22H34O7Purity:98.83% - 99.96%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.5HJC0350
CAS:<p>HJC0350 is an effective and specific EPAC2 inhibitor (IC50: 0.3 μM), and no inhibition of Epac1.</p>Formula:C15H19NO2SPurity:99.27% - 99.65%Color and Shape:SolidMolecular weight:277.38Enoximone
CAS:<p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>Formula:C12H12N2O2SPurity:98.53%Color and Shape:SolidMolecular weight:248.3LY404039
CAS:<p>LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).</p>Formula:C7H9NO6SPurity:99% - 99.92%Color and Shape:SolidMolecular weight:235.22Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
<p>Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.</p>Color and Shape:Lyophilized PowderMolecular weight:24.7 kDa (predicted)Uliledlimab
CAS:<p>Uliledlimab, a humanized monoclonal antibody against CD73, reduces extracellular adenosine production and modulates immunosuppressive pathways.</p>Purity:95% - 95%Color and Shape:LiquidI942
CAS:<p>I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical</p>Formula:C20H19NO4SPurity:99.75%Color and Shape:SolidMolecular weight:369.43ESI-08
CAS:<p>ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.</p>Formula:C20H23N3OSPurity:97.17%Color and Shape:SolidMolecular weight:353.48EPAC 5376753
CAS:<p>EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.</p>Formula:C15H8Cl2N2O3SPurity:97.48%Color and Shape:SolidMolecular weight:367.21Rp-cAMPS sodium
CAS:<p>Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a PKA inhibitor and cAMP antagonist that inhibits cAMP-dependent protein kinases.</p>Formula:C10H11N5NaO5PSPurity:99.71%Color and Shape:SolidMolecular weight:367.25KI-7
CAS:<p>KI-7 is an adenosine A2B receptor positive allosteric modulator.</p>Formula:C23H18N2O2Purity:98.33%Color and Shape:SolidMolecular weight:354.4UNC0006
CAS:<p>UNC0006 is a β-arrestin-biased dopamine D2 ligand.</p>Formula:C24H29Cl2N3O2Purity:99.35% - 99.97%Color and Shape:SolidMolecular weight:462.41Torbafylline
CAS:<p>Torbafylline is a xanthine-based PDE inhibitor reducing protein breakdown via PDE4/cAMP/EPAC/PI3K/Akt in rats with burns, cancer, or sepsis.</p>Formula:C16H26N4O4Purity:98.66% - 99.13%Color and Shape:SoildMolecular weight:338.4CJ-42794
CAS:<p>CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4).</p>Formula:C22H17ClFNO4Purity:99.92%Color and Shape:SolidMolecular weight:413.83NCGC00229600
CAS:<p>NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.</p>Formula:C30H29N3O3Purity:99.31%Color and Shape:SolidMolecular weight:479.57CW 008
CAS:<p>CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.</p>Formula:C21H14F2N6O2Purity:97.39%Color and Shape:SolidMolecular weight:420.37TP-10
CAS:<p>TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.</p>Formula:C26H19F3N4OPurity:99.21%Color and Shape:SolidMolecular weight:460.45LGD-6972
CAS:<p>LGD-6972 is an antagonist of glucagon receptor.</p>Formula:C43H46N2O5SPurity:98.8% - 99.62%Color and Shape:SolidMolecular weight:702.9Vidupiprant
CAS:<p>Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.</p>Formula:C28H27Cl2FN2O6SPurity:98.88%Color and Shape:SolidMolecular weight:609.49
